Contrast-Enhanced Conventional CT in Patients after Surgery for Malignant Tumors. Evaluation of the Optimal Method of the Administration of the Contrast Medium.

In this article, based on two clinical examples, the possibilities of multiparametric ultrasound in the differential diagnosis of metastatic and lymphoproliferative changes in lymph nodes in primary-multiple malignant tumors, including breast cancer and lym - phoma, are evaluated. Multiparameteric ultrasound includes B-mode, color and energy Doppler imaging, strain elastography, shear wave elastography and contrast-enhanced ultrasound (CEUS). Standardization and reproducibility of these ultrasound techniques will allow to objectify the study, obtaining specific indicators of shear wave velocity in the zones of interest and specific signs of contrast enhancement, which can be used as impor tant differential diagnostic tool in oncology.

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New technologies in breast cancer detection – contrast enhanced dual-energy spectral mammography

Medical Visualization ◽

10.24835/1607-0763-2019-2-49-61 ◽

2019 ◽

pp. 49-61

Author(s):

A. V. Chernaya ◽

S. N. Novikov ◽

P. V. Krivorotko ◽

R. Kh. Ulyanova ◽

V. V. Danilov

Keyword(s):

Breast Cancer ◽

Digital Mammography ◽

Predictive Value ◽

New Technologies ◽

Malignant Tumors ◽

Dual Energy ◽

Post Contrast ◽

Morphological Studies ◽

Contrast Enhanced ◽

Sensitivity Specificity

Purpose: to study the possibilities of contrast enhanced dual-energy spectral mammography (CESM) in the diagnostics of malignant tumors in the breast.Material and methods. Forty-seven patients with suspicious for breast cancer (BC) lesions underwent CESM. Digital mammography (MMG) and post-contrast images were correlated with the results of path morphological studies after surgery or puncture biopsy was performed.Results. Sensitivity, specificity and overall accuracy in the diagnostics of breast cancer were 83.3%, 85.7%, 85.1% for digital mammography and 91.6%, 91.4%, 91.4% for CESM, respectively. The positive predictive value was 66.6% for digital MMG and 78.5% for CESM. The negative predictive value (NPV) was 96.9% for the CESM and exceeded NPV of the digital MMG, which was 93.7%.Conclusion. Thus, these findings suggest that CESM is an effective method for the diagnostics of malignant tumors in the breast.

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Contrast-enhanced angiographic cone-beam computed tomography without pre-diluted contrast medium

Neuroradiology ◽

10.1007/s00234-015-1570-0 ◽

2015 ◽

Vol 57 (11) ◽

pp. 1121-1126 ◽

Cited By ~ 3

Author(s):

K. I. Jo ◽

S. R. Kim ◽

J. H. Choi ◽

K. H. Kim ◽

P. Jeon

Keyword(s):

Computed Tomography ◽

Contrast Medium ◽

Cone Beam Computed Tomography ◽

Cone Beam ◽

Contrast Enhanced

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Use-fullness of dynamic contrast-enhanced MR imaging and diffusion weighted MR imaging for differentiation of benign and malignant parotid tumors

10.36879/jcmi.18.000101 ◽

2018 ◽

pp. 1-6

Keyword(s):

Mr Imaging ◽

Malignant Tumors ◽

Dce Mri ◽

Dynamic Contrast Enhanced ◽

Parotid Tumors ◽

Contrast Enhanced ◽

Type C ◽

Sensitivity Specificity ◽

And Diffusion ◽

Malignant Parotid Tumors

Objectives: To evaluate the usefullness of dynamic contrast-enhanced MR Imaging (DCE-MRI) and diffusion weighted imaging (DWI) for differentiating benign from malignant parotid tumors. Methods: Prospectively,DCE-MRI and DWI were performed in 112 patients, with 148 confirmed parotid masses. The differential optimal thresholds were determined. Results: WConsidering tumors with time-intensity curve (TIC) Type C as malignant, sensitivity, specificity, accuracy were 95%, 76%, 79%, respectively. Considering ADC threshold values 0.709×10-3mm2 /s<ADC<0.948×10-3mm2 /s as malignant, sensitivity, specificity, accuracy were 75%, 78%, 78%, respectively. Considering TIC Type C and ADC values 0.709×10-3mm2 /s<ADC<0.948×10-3mm2 /s as malignant, sensitivity, specificity, accuracy were 75%, 91%, 89%, respectively. With threshold Kep<1.118 min-1 and Ve >0.315 between Warthin and malignant tumors, threshold Kep>0.555 min-1 and Ve <0.605 between pleomorphic adenomas and malignant tumors, sensitivity, specificity, accuracy for malignancy were 70% vs 90%, 96% vs 74%, 92% vs 80%, respectively. Conclusion: DCE-MRI and DWI provide more information in differentiating benign from malignant parotid tumors.

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Nephrotoxic Polypharmacy and Risk of Contrast Medium–Induced Nephropathy in Hospitalized Patients Undergoing Contrast-Enhanced CT

American Journal of Roentgenology ◽

10.2214/ajr.15.14329 ◽

2015 ◽

Vol 205 (4) ◽

pp. 703-708 ◽

Cited By ~ 5

Author(s):

Yunn-Fang Ho ◽

Kun-Lin Hsieh ◽

Fan-Lu Kung ◽

Fe-Lin Lin Wu ◽

Ling-Ling Hsieh ◽

...

Keyword(s):

Contrast Medium ◽

Hospitalized Patients ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct

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Contrast-enhanced computed tomography of the liver, gall bladder and urogenital tract in female red-eared terrapins (Trachemys scripta elegans)

Veterinární Medicína ◽

10.17221/73/2017-vetmed ◽

2017 ◽

Vol 62 (No. 12) ◽

pp. 674-680 ◽

Cited By ~ 2

Author(s):

V. Sochorcova ◽

P. Proks ◽

E. Cermakova ◽

Z. Knotek

Keyword(s):

Computed Tomography ◽

Gall Bladder ◽

Contrast Medium ◽

Bladder Wall ◽

Post Contrast ◽

Contrast Medium Administration ◽

Contrast Enhanced ◽

Enhanced Computed Tomography ◽

Contrast Enhanced Computed Tomography ◽

Contrast Studies

The aim of the present study was to evaluate the feasibility of contrast-enhanced computed tomography for organ morphology and perfusion in five captive terrapins. Native scans were performed and afterwards an iodinated non-ionic contrast media was manually administered through the jugular vein catheter. Post-contrast CT scans were taken 20 (T20), 60 (T60) and 180 (T180) seconds after the contrast medium administration. Maximum contrast enhancement of the kidneys and the liver was detected at T20 and T60, respectively. The gall bladder content, the urinary bladder content and ovarian follicles were all without contrast enhancement in all five terrapins. Gall bladder wall thickness was 0.9 mm in all terrapins. Enhancement of the gall bladder wall in post-contrast studies was considered excellent, good or poor in two terrapins, two terrapins and one terrapin, respectively, with a mean score of 1.8 ± 0.84 over all contrast studies. Enhancement of the ureters in post-contrast studies was considered excellent in all terrapins in all contrast studies. Peak aortic enhancement was reached 20 seconds after contrast medium administration with the peak enhancement of 213.5 ± 41 HU in four terrapins and 560 HU in one terrapin. Peak hepatic vein enhancement after contrast medium administration was recorded 20 and 60 seconds in two and three terrapins, respectively. In conclusion, contrast-enhanced computed tomography proved to be a valuable method for clinical examination of the liver, gall bladder, kidneys, ureters, urinary bladder and ovarian follicles in red-eared terrapins.

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Image artifacts due to a time-varying contrast medium concentration in 3D contrast-enhanced MRA

Journal of Magnetic Resonance Imaging ◽

10.1002/(sici)1522-2586(199912)10:6<919::aid-jmri3>3.0.co;2-w ◽

1999 ◽

Vol 10 (6) ◽

pp. 919-928 ◽

Cited By ~ 41

Author(s):

Jonas Svensson ◽

J. Stefan Petersson ◽

Freddy St�hlberg ◽

Elna-Marie Larsson ◽

Peter Leander ◽

...

Keyword(s):

Contrast Medium ◽

Image Artifacts ◽

Time Varying ◽

Medium Concentration ◽

Contrast Enhanced ◽

Contrast Medium Concentration

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Values of thoracic contrast‑enhanced computed tomography in detecting incidental pulmonary thromboembolism in patients with malignant tumors

Oncology Letters ◽

10.3892/ol.2018.9578 ◽

2018 ◽

Author(s):

Lijuan Dai ◽

Gaofeng Shi ◽

Yang Li ◽

Bo Zhao

Keyword(s):

Computed Tomography ◽

Pulmonary Thromboembolism ◽

Malignant Tumors ◽

Contrast Enhanced ◽

Enhanced Computed Tomography ◽

Contrast Enhanced Computed Tomography

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Small Subcutaneous Soft Tissue Tumors (<5 cm) Can Be Sarcomas and Contrast-Enhanced Ultrasound (CEUS) Is Useful to Identify Potentially Malignant Masses

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17238868 ◽

2020 ◽

Vol 17 (23) ◽

pp. 8868

Author(s):

Armanda De Marchi ◽

Simona Pozza ◽

Lorena Charrier ◽

Filadelfo Cannone ◽

Franco Cavallo ◽

...

Keyword(s):

Soft Tissue ◽

Malignant Tumors ◽

Univariate Analysis ◽

Soft Tissue Tumors ◽

Deep Fascia ◽

Contrast Enhanced Ultrasound ◽

Predictive Values ◽

Contrast Enhanced ◽

Potentially Malignant ◽

Sensitivity Specificity

Subcutaneous masses smaller than 5 cm can be malignant, in contrast with the international guidelines. Ultrasound (US) and magnetic resonance imaging (MRI) are useful to distinguish a potentially malignant mass from the numerous benign soft tissue (ST) lesions. Contrast-enhanced ultrasound (CEUS) was applied in ST tumors, without distinguishing the subcutaneous from the deep lesions. We evaluated CEUS and MRI accuracy in comparison to histology in differentiating malignant from nonmalignant superficial ST masses, 50% smaller than 5 cm. Sensitivity, specificity, and positive and negative predictive values (PPV, NPV) with their 95% confidence intervals (CI) were calculated. Of malignant cases, 44.4% measured ≤5 cm. At univariate analysis, no statistically significant differences emerged between benign and malignant tumors in relation with clinical characteristics, except for relationship with the deep fascia (p = 0.048). MRI accuracy: sensitivity 52.8% (CI 37.0, 68.0), specificity 74.1% (CI 55.3, 86.8), PPV 73.1% (CI 53.9, 86.3), and NPV 54.1% (CI 38.4, 69.0). CEUS accuracy: sensitivity 75% (CI 58.9, 86.3), specificity 37% (CI 21.5, 55.8), PPV 61.4% (CI 46.6, 74.3), and NPV 52.6% (CI 31.7, 72.7). CEUS showed a sensitivity higher than MRI, whereas PPV and NPV were comparable. Also, masses measuring less than 5 cm can be malignant and referral criteria for centralization could be revised.

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