Diagnostic Performance of Prospectively Assigned Likert Scale Scores to Determine Extraprostatic Extension and Seminal Vesicle Invasion With Multiparametric MRI of the Prostate

2019 ◽  
Vol 212 (3) ◽  
pp. 576-581 ◽  
Author(s):  
Yuval Freifeld ◽  
Alberto Diaz de Leon ◽  
Yin Xi ◽  
Ivan Pedrosa ◽  
Claus G. Roehrborn ◽  
...  
2017 ◽  
Vol 89 (1) ◽  
pp. 71 ◽  
Author(s):  
Mustafa Yuksel ◽  
Kaan Karamık ◽  
Hakan Anıl ◽  
Ekrem Islamoglu ◽  
Mutlu Ates ◽  
...  

Objectives: After radical prostatectomy, surgical margin positivity is an important indicator of biochemical recurrence and progression. In our study we want to compare the surgical margin positivity rates for retropubic radical prostatectomy (RRP) and robotic assisted radical prostatectomy (RALP) and investigate the factors affecting surgical margin positivity in RALP. Materials and methods: Data from 78 RRP and 62 RALP patients operated from 2011 May to 2016 March were retrospectively screened. Patients in both groups were compared in terms of age, postop hematocrit reduction, hospital stay, duration of follow-up, surgical margin positivity, biochemical recurrence and oncologic parameters. In RALP group it was searched the relationship between the surgical margin positivity and prostate specific antigen (PSA), positive biopsy core, biopsy Gleason scoring, pathologic stage and Gleason scoring, lymph node positivity, lymphovascular and perineural invasion, extracapsular extension, seminal vesicle invasion, prostate weight. Results: Patients in the RALP group had lower postop hematocrit reduction and shorter hospital stay (p < 0.001). There was no difference in surgical margin positivity between RALP and RRP groups (37.1% vs. 29.5%, p = 0.341). In RALP group there was a correlation between surgical margin positivity and positive biopsy core number (p = 0.011), pathologic stage (p < 0.001) and Gleason score (p < 0.001), EAU risk classification (p = 0.001), seminal vesicle invasion (p = 0.045), extraprostatic extension (p < 0.001). There was no correlation between prostate weight (p = 0.896), PSA (p = 0.220), biopsy Gleason score (p = 0.266), lymph node positivity (p = 0.140), perineural (p = 0.103) and lymphovascular invasion (p = 0.92) with surgical margin positivity. Conclusions: Positive biopsy core number, pathological stage and Gleason score, EAU risk classification, seminal vesicle invasion and extraprostatic extension are correlated with surgical margin positivity in RALP.


2020 ◽  
Vol 2 (1) ◽  
pp. e190071 ◽  
Author(s):  
Lars A. R. Reisæter ◽  
Ole J. Halvorsen ◽  
Christian Beisland ◽  
Alfred Honoré ◽  
Karsten Gravdal ◽  
...  

В статье представлены три клинических наблюдения, которые демонстрируют полезность ультразвуковой информации, полученной при мультипараметрическом трансректальном ультразвуковом исследовании, в оценке местного распространения рака предстательной железы. Ультразвуковая картина верифицирована данными мультипараметрической магнитно-резонансной томографии и трансректальной мультифокальной системной пункционной биопсии предстательной железы из 12 точек под контролем ультразвукового исследования, дополненной прицельной биопсией из подозрительных на злокачественность очагов, выявленных при мультипараметрическом трансректальном ультразвуковом исследовании. Представлен краткий обзор литературы, который показывает, что на сегодняшний день мультипараметрическая ультразвуковая диагностика не позволяет с приемлемой диагностической точностью выполнить предоперационное стадирование рака предстательной железы. Как и другие методы ультразвуковой диагностики (серошкальная визуализация, 3D-визуа лизация, цветокодированные допплерографические режимы), эластография сдвиговой волной не рассматривается в рутинной практике среди инструментальных методов, осуществляющих стадирование по категории Т. Но в тех случаях, когда врач ультразвуковой диагностики выявляет с помощью эластографии сдвиговой волной (как и с помощью серошкального и цветокодированных допплерографических режимов) признаки экстрапростатического распространения опухоли или прорастания опухоли в семенные пузырьки, он может указать эти данные в протоколе ультразвукового исследования. Ключевые слова: ультразвуковая эластография сдвиговой волной, жесткость, модуль Юнга, предстательная железа, рак предстательной железы, стадирование, экстрапростатическое распространение, инвазия в семенные пузырьки, ultrasound shear wave elastography, stiffness, Young’s modulus, prostate, prostate cancer, staging, extraprostatic extension, seminal vesicle invasion


Radiology ◽  
2019 ◽  
Vol 293 (2) ◽  
pp. 350-358 ◽  
Author(s):  
Urs J. Muehlematter ◽  
Irene A. Burger ◽  
Anton S. Becker ◽  
Khoschy Schawkat ◽  
Andreas M. Hötker ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Wei Li ◽  
Yuan Sun ◽  
Yiman Wu ◽  
Feng Lu ◽  
Hongtao Xu

PurposeTo investigate the diagnostic performance of using quantitative assessment with multiparametric MRI (mpMRI) for prediction of extraprostatic extension (EPE) in patients with prostate cancer (PCa).MethodsWe performed a computerized search of MEDLINE, Embase, Cochrane Library, Web of Science, and Google Scholar from inception until July 31, 2021. Summary estimates of sensitivity and specificity were pooled with the bivariate model, and quality assessment of included studies was performed with the Quality Assessment of Diagnostic Accuracy Studies-2. We plotted forest plots to graphically present the results. Multiple subgroup analyses and meta-regression were performed to explore the variate clinical settings and heterogeneity.ResultsA total of 23 studies with 3,931 participants were included. The pooled sensitivity and specificity for length of capsular contact (LCC) were 0.79 (95% CI 0.75–0.83) and 0.77 (95% CI 0.73–0.80), for apparent diffusion coefficient (ADC) were 0.71 (95% CI 0.50–0.86) and 0.71 (95% CI 059–0.81), for tumor size were 0.62 (95% CI 0.57–0.67) and 0.75 (95% CI 0.67–0.82), and for tumor volume were 0.77 (95% CI 0.68–0.84) and 0.72 (95% CI 0.56–0.83), respectively. Substantial heterogeneity was presented among included studies, and meta-regression showed that publication year (≤2017 vs. >2017) was the significant factor in studies using LCC as the quantitative assessment (P=0.02).ConclusionFour quantitative assessments of LCC, ADC, tumor size, and tumor volume showed moderate to high diagnostic performance of predicting EPE. However, the optimal cutoff threshold varied widely among studies and needs further investigation to establish.


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