scholarly journals A clinical case of the retroperitoneal fibrosis (Ormond's disease) in rheumatology practice

2021 ◽  
Vol 11 (1) ◽  
pp. 42-49
Author(s):  
S.А. Trypilka ◽  
Ye.D. Yehudina
Keyword(s):  
Clinical Case ◽  
Retroperitoneal Fibrosis ◽  
Abdominal Cavity ◽  
Fibrous Tissue ◽  
Malignant Neoplasms ◽  
Immunoglobulin G4 ◽  
Iliac Arteries ◽  
Pathogenetic Therapy ◽  
Clinical Interest ◽  
Rheumatology Practice

Retroperitoneal fibrosis (RPF) is a rare disease cha­racterized by the proliferation of inflammatory and fibrous tissue in the retroperitoneum. These masses are commonly loca­lized around the infrarenal part of the abdominal aorta and iliac arteries, often covering the ureters or other organs of the abdominal cavity; idiopathic diseases accounting for 70 % of cases. RPF may be associated with immunoglobulin G4 (IgG4), which accounts for two-thirds of idiopathic RPF cases. Secondary RPF may develop due to infections, malignant neoplasms, medication, retroperitoneal bleeding, or various other diseases. A cli­nical case of idiopathic RPF, probably associated with IgG4, was described in a patient who had undergone a symptomatic surgical treatment in an urological clinic and continued being trea­ted by a rheumatologist, given pathogenetic therapy (methylpredni­solone and mycophenolate mofetil) with a significant improvement. For rheumatologists, this pathology is of an undoubted clinical interest, since these changes are based on processes si­milar to those occurring in systemic diseases of the connective tissue, and the RPF is extremely rare, ranging from 0.1 to 1.3 cases per 100,000 patients per year. However, more often than not, such patients are referred to the doctors of ancillary specialties (urologists, nephrologists, surgeons, vascular surgeons). All of the abovementioned facts emphasize the importance of analyzing such a clinical case.

Retroperitoneal fibrosis

2015 ◽  
Author(s):  
Muhammad M. Yaqoob ◽  
Katherine Bennett-Richards ◽  
Islam Junaid
Keyword(s):  
Abdominal Aorta ◽  
Retroperitoneal Fibrosis ◽  
Fibrous Tissue ◽  
Histological Diagnosis ◽  
Iliac Arteries ◽  
Large Sample ◽  
Regular Monitoring ◽  
Ureteric Stents ◽  
Secondary Causes ◽  
Inflammatory Tissue

Retroperitoneal fibrosis (RPF) is a rare but multifaceted disease which encompasses a range of conditions characterized by the presence of a fibro-inflammatory tissue, which usually surrounds the abdominal aorta, iliac arteries, and extends into the retroperitoneum to entrap ureters with resultant unilateral or bilateral obstruction, usually at the junction between the middle and lower thirds of the ureter. The condition is progressive: initially, the fibrous tissue is fairly cellular, later becoming relatively acellular. The mechanism by which obstruction occurs is probably due to loss of peristalsis. A histological diagnosis should be obtained if at all possible, and laparotomy is required in order to obtain a sufficiently large sample to differentiate between idiopathic and secondary causes of RPF. Treatment of idiopathic RPF is by corticosteroids in the first instance with ureteric stents or ureterolysis initially and requires regular monitoring.

Clinical case of lung lesions in patient with newly diagnosed systemic lupus erythematosus

2019 ◽  
Vol 1 (9) ◽  
pp. 53-57
Author(s):  
T. N. Gavva ◽  
L. V. Kuzmenkova ◽  
Yu. N. Fedulaev ◽  
T. V. Pinchuk ◽  
D. D. Kaminer ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Lung Damage ◽  
Newly Diagnosed ◽  
Systemic Lupus ◽  
Lung Lesions ◽  
Laboratory Parameters ◽  
Clinical Interest

A case of lung damage in systemic lupus erythematosus (SLE) in a 33-year-old woman is described. This case is of clinical interest due to the complexity of diagnosis due to the fact that SLE is a disease with diverse clinical manifestations involving many organs and systems, which often makes it difficult to timely recognize the onset of the disease. SLE still remains a challenge and requires special attention to the patient s history, clinical and laboratory parameters of the patient, as well as specific immunological examinations.

AB1377 Clinical interest of bone marrow examination in rheumatology practice: An observationnal study of 257 patients

2013 ◽  
Vol 71 (Suppl 3) ◽  
pp. 716.12-716
Author(s):  
P. Ornetti ◽  
A. Loctin ◽  
C. Fortunet ◽  
J.-F. Maillefert ◽  
C. Tavernier
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Examination ◽  
Clinical Interest ◽  
Rheumatology Practice

CLINICAL CASE: STEROID-RESISTANT NEPHROTIC SYNDROME

2021 ◽  
pp. 13-17
Author(s):  
А.Е. Турсын
Keyword(s):  
Quality Of Life ◽  
Nephrotic Syndrome ◽  
Arterial Hypertension ◽  
Clinical Case ◽  
Steroid Resistant ◽  
Steroid Resistant Nephrotic Syndrome ◽  
Moderate Severity ◽  
Syndrome Diagnosis ◽  
Pathogenetic Therapy

Описан клинический случай пациент с нефротическим синдромом, стероид резистентный вариант, с артериальной гипертензией, осложненный полисерозитом (гидроторакс, асцит, плеврит). Пациент поступил в клинику в состоянии средней степени тяжести, с массивными отеками, полисерозитом, артериальной гипертензией и выраженным нефротическим синдромом. Диагноз: Гломерулярная болезнь. Нефротический синдром, стероид резистентный вариант. Функция почек снижена (СКФ- 84мл/мин по Шварцу). Двухсторонний экссудативный плеврит. Гидроторакс. Полисерозит (в рамках нефротического синдрома) был установлен на основании выраженного нефротического синдрома. Пациенту была проведена патогенетическая терапия. Отмечено улучшение состояния больного, в виде снижения отеков, нормализаций артериального давления, что в свою очередь поспособствовало сохранению и улучшению качества жизни пациента. A clinical case of a patient with nephrotic syndrome, steroidresistant variant, with arterial hypertension complicated by polyserositis (hydrothorax, ascites, pleurisy) is described. The patient was admitted to the clinic in a state of moderate severity, with massive edema, polyserositis, arterial hypertension, and severe nephrotic syndrome. Diagnosis: Glomerular disease. Nephrotic syndrome, steroidresistant variant. The kidney function is reduced (GFR - 84 ml/min according to Schwartz). Bilateral exudative pleurisy. Hydrothorax. Polyserositis (within the framework of nephrotic syndrome) was established based on the severe nephrotic syndrome. The patient underwent pathogenetic therapy. An improvement in the patient's condition was noted, in the form of a decrease in edema, normalization of blood pressure, which in turn contributed to the preservation and improvement of the patient's quality of life.

scholarly journals Variations in the aortic - common iliac bifurcation in man - a cadaveric study

2013 ◽  
Vol 02 (02) ◽  
pp. 056-060
Author(s):  
Maneesha Sharma ◽  
Tripta Sharma ◽  
Richhpal Singh
Keyword(s):  
Abdominal Aorta ◽  
Abdominal Cavity ◽  
Lumbar Vertebra ◽  
Anatomical Variations ◽  
Iliac Arteries ◽  
Medical College ◽  
Great Vessels ◽  
Exact Position ◽  
Vertebral Bodies ◽  
Common Iliac Arteries

Abstract Background and aims: The abdominal aorta usually terminates at the level of L4 vertebral body into common iliac arteries. With the present day advancements in vascular surgery and neurological surgeries involving approach to lumbar vertebral bodies, we need to know any variations from this normal course. So, the present study aimed at knowing the anatomical variations in the termination of abdominal aorta and in common iliac arteries which might prove to be of some help in some of such surgeries. Material and methods: The study was conducted on 35 adult (29 males and 6 females) embalmed cadavers obtained from anatomy departments of Govt. Medical college, Amritsar and Gian Sagar Medical college, Ramnagar, Punjab. The abdominal cavity was opened, peritoneum stripped off from aorta at its bifurcation, variations in its termination, common iliac arteries and their branches were carefully observed and recorded. Results: In 54.29% cases the level of aortic bifurcation was found opposite 4th Lumbar vertebra, in the rest it was variable between L3 and L5 vertebra. Conclusions: These variations may lead to some trouble during vertebral surgeries, making it essential to investigate and locate the exact position of great vessels before the commencement of surgery.

scholarly journals Endometriosis as a Reason of Intraabdominal Bleeding in Pregnancy. Clinical Case

2019 ◽  
Vol 23 (3) ◽  
pp. 283-289
Author(s):  
Y. A. Revzoeva ◽  
E. Y. Shakurova
Keyword(s):  
Cesarean Section ◽  
Pregnant Women ◽  
Laboratory Tests ◽  
Clinical Case ◽  
Abdominal Cavity ◽  
Diagnostic Procedures ◽  
Reproductive Period ◽  
Diagnostic Methods ◽  
Dark Blood ◽  
Abdominal Bleeding

The article defines the significance and relevance of the problem of endometriosis during pregnancy. 10% of women in the reproductive period have different localization of endometriosis. 25% of pregnancies with endometriosis are complicated by preterm labor. The article presents a clinical case of intra-abdominal bleeding in a 28-year-old pregnant woman with retrocervical endometriosis at gestation age of 32 weeks and 6 days. The article covers the results of examination and special diagnostic procedures of intra-abdominal bleeding in pregnant women with retrocervical endometriosis. The main diagnostic methods were the study of past medical history, ultrasound examination, and laboratory tests. Due to their infrequency during pregnancy internal bleedings present difficulties in their diagnosis. Ultrasound reliably revealed a large amount of fluid in the abdominal cavity and small pelvis and excluded the presence of intrauterine bleeding. Clinical and laboratory tests indicated the severity of the patient's condition. Symptoms of moderate fetal distress were also identified. Therefore, a decision was made about an emergency delivery by the cesarean section followed by an abdominal revision. During the cesarean section, 500 ml of blood in the form of dark blood clots was found in the abdominal cavity. The condition of the premature newborn was in conformity with his gestational age. The source of bleeding were the of endometriosis on the back wall of the uterus. These focuses most likely caused hemoperitoneum. The revision of the abdominal cavity did not find any other foci of bleeding. The postoperative period was uneventful. The article provides general guidelines for the management of pregnant women with severe forms of endometriosis.

scholarly journals CLINICAL AND EPIDEMIOLOGICAL ANALYSIS OF MALIGNANT NEOPLASMS OF THE ABDOMINAL ORGANS

2021 ◽  
Vol 19 (4) ◽  
Author(s):  
I.A. Malishevsky
Keyword(s):  
Developmental Stages ◽  
Abdominal Cavity ◽  
Malignant Neoplasms ◽  
Newly Diagnosed ◽  
Epidemiological Analysis ◽  
Software Packages ◽  
Abdominal Organs ◽  
Microsoft Office ◽  
Epidemiological Characteristics ◽  
Epidemiological Parameters

Purpose – to determine the statistical and epidemiological parameters of malignantneoplasms of the abdominal cavity organs.Material and methods. The study was carried out on the basis of the Chernivtsi RegionalClinical Oncological Dispensary and covers observation materials during 2019 andstatistical reporting concerning 21259 patients with tumors of various localization. The calculation of indices was carried out using software packages MS Access and MS Excelbased on the Microsoft Office medium.Results. Neoplasms of the abdominal organs account for 32.4%-37.1% of the totalnumber of neoplasms of various localization. The distribution of patients with malignantdiseases of the abdominal organs by developmental stages is relatively uniform, despitesignificant differences in various localizations of neoplasmsConclusions. Malignant neoplasms of the abdominal organs account for 32.4%(registered) and 37.1% of the newly diagnosed of the total number of tumors of variouslocalization, indicating the importance of further research. A significant part of tumors ofthe abdominal cavity organs are diagnosed in the late (III-IV) stages of the pathologicalprocess development (up to 94.7% in the liver and intrahepatic biliary tract). Therevealed significant differences in clinical and epidemiological characteristics requirefurther research.

scholarly journals Perforated Peptic Ulcer Combined with Posttraumatic Diaphragmatic Hernia in Third Gestation Trimester: a Clinical Case

2021 ◽  
Vol 11 (3) ◽  
pp. 251-255
Author(s):  
V. S. Panteleev ◽  
I. B. Fatkullina ◽  
A. Kh. Mustafin ◽  
R. S. Khalitova ◽  
A. S. Petrov
Keyword(s):  
Peptic Ulcer ◽  
Pregnant Women ◽  
Diaphragmatic Hernia ◽  
Clinical Case ◽  
Abdominal Cavity ◽  
Perforated Peptic Ulcer ◽  
Favourable Outcome ◽  
Duodenal Perforation ◽  
Duodenal Ulcers ◽  
In Pregnancy

Background. Gastric and duodenal ulcers are extremely rare in pregnancy, according to published literature. Peptic ulcer is found in 1 per 4,000 pregnant women, a figure probably underestimated due to its hampered diagnosis in pregnancy. Pregnancy peptic ulcer is considered less expected. Perforated gastric and duodenal ulcers comprise about 1.5 % of total acute abdominal diseases, and the perforation rate in ulcer patients ranges within 5–15 %. This complication afflicts the ages of 20–40 years in men much more frequently than in women. Three perforation types occur: free into abdominal cavity (87 %), contained (9 %), into lesser omentum and retroperitoneal tissue (4 %).Materials and methods. The clinical case describes surgical management of posttraumatic diaphragmatic hernia-comorbid perforated gastric ulcer in a pregnant woman in third trimester. Surgery with postoperative patient management enabled for a favourable outcome.Results and discussion. Perforation-entailing gastric and duodenal ulcers in pregnant women have received negligible attention due to rarity in clinical practice. Paul et al. described 14 cases of duodenal perforation in pregnancy, all fatal.Conclusion. Early diagnosis of surgical pathology during gestation is still difficult contributing to the development of severe complications associated with high mortality. The patient’s admission to a level III interspecialty hospital was key to enable a timely consilium-driven decision of caesarean intervention for saving the child, diagnosing intraoperatively life-threatening complicated surgical diseases and opting for radical surgery that ended in a favourable outcome.

Retroperitoneal fibrosis showing immunoglobulin G4-positive monoclonal B-lymphocytes

2011 ◽  
Vol 52 (11) ◽  
pp. 2179-2181 ◽  
Author(s):  
Masaru Kojima ◽  
Tadashi Motoori ◽  
Masahumi Nishikawa ◽  
Hazuki Matsuda ◽  
Nobuhide Masawa ◽  
...  
Keyword(s):  
B Lymphocytes ◽  
Retroperitoneal Fibrosis ◽  
Immunoglobulin G4

scholarly journals A clinical case of polyneoplasia

2018 ◽  
Vol 99 (2) ◽  
pp. 304-306
Author(s):  
F A Akhmetzyanov ◽  
N A Valiev ◽  
V I Egorov ◽  
D V Burba
Keyword(s):  
Gastrointestinal Tract ◽  
Clinical Case ◽  
Malignant Neoplasms ◽  
Duodenal Papilla ◽  
Single Patient ◽  
Synchronous Tumors ◽  
Multiple Tumors ◽  
Multiple Neoplasms ◽  
Oncologic Patients ◽  
Current Article

Primary multiple neoplasms (polyneoplasia) are among the interesting and insufficiently studied fields of oncology. The term polyneoplasia is usually used for two or more malignant neoplasms in a single patient, which occur synchronously or metachronously. Over the last decade, an increase of primary multiple tumors prevalence has been observed. In 2015 39 195 new cases of primary multiple tumors were registered in Russia and comprised 6.7% of all incident malignant neoplasms. Primary multiple metachronous and primary multiple synchronous tumors with two neoplasms development are observed most often, with three more rarely, and with four or more very rarely. In average, 0.1% of a total number of oncologic patients have at least three malignant neoplasms. Primary multiple tumors of gastrointestinal tract are observed most often. The current article presents a clinical case of four synchronous tumors in a single patient localized in major duodenal papilla, sigmoid, transverse colon and lung.

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