scholarly journals Radiochemical Separation of 161Tb from Gd/Tb Matrix Using Ln Resin Column

2018 ◽  
Vol 16 (3) ◽  
pp. 283 ◽  
Author(s):  
Azmairit Aziz ◽  
Widya Tania Artha
Keyword(s):  
Optimum Condition ◽  
Radiochemical Separation ◽  
Resin Column ◽  
Chromatography Method ◽  
Hno3 Solution ◽  
Radionuclide Purity ◽  
Γ Rays ◽  
Ge Detector ◽  
Preliminary Study ◽  
Ln Resin

Terbium-161 (161Tb) is a potential radiolanthanide due to its favorable properties for treatment small size of cancer. Preliminary study on radiochemical separation of 161Tb from Gd/Tb matrix using Ln resin column based on extraction chromatography method has been carried out. 161Tb radionuclide was produced by irradiation of natural Gd2O3 target through neutron thermal bombardment at G.A. Siwabessy Multipurpose Reactor. Fractions eluted from the column containing Gd/Tb matrix of irradiated natural Gd2O3 target were identified and quantified using a γ-rays spectrometer with HP-Ge detector coupled to a multichannel analyzer. The results show that the optimum condition on 161Tb separation from irradiated Gd2O3 target with radionuclide purity 99.27 ± 0.30% was obtained using HNO3 solution with concentration of 0.8 and 3 N to separate gadolinium and terbium isotope, respectively. The yield of 161Tb obtained from the separation was 61.21 ± 2.05% and Gd recovered was 97.15 ± 2.23%. Based on this experiment, 161Tb has been separated from irradiated natural gadolinium oxide target with high radionuclide purity.

The branching ratio in the decay of 7Be

1984 ◽  
Vol 62 (11) ◽  
pp. 1139-1144 ◽  
Author(s):  
H. C. Evans ◽  
I. P. Johnstone ◽  
J. R. Leslie ◽  
W. McLatchie ◽  
H.-B. Mak ◽  
...  
Keyword(s):  
Axial Vector ◽  
Branching Ratio ◽  
Experimental Result ◽  
Vector Coupling ◽  
A Value ◽  
Axial Vector Coupling ◽  
Absolute Efficiency ◽  
Γ Rays ◽  
Ge Detector ◽  
The Absolute

A measurement of the branching ratio for electron capture (EC) decay of 7Be to the 478-keV level in 7Li is reported. The reaction 10B(p, α)7Be was used and the 7Be recoils were detected and stopped in a particle detector thin enough to transmit the protons. The absolute γ-ray emission rate of 478-keV γ rays from the implanted detector was determined with a well-shielded intrinsic Ge detector. The absolute efficiency of the Ge detector was established with 22Na, 137Cs, and 88Y standard sources. A value of 11.4 ± 0.7% was obtained for the EC branch to the 478-keV state. Calculations suggest that the axial vector coupling constant GA must be reduced by a factor of 0.94 ± 0.02 to obtain agreement with the experimental result.

METHOD OF QUANTITATIVE ANALYSIS OF FLUORINE IN ENVIRONMENTAL SAMPLES USING A PURE-Ge DETECTOR

2004 ◽  
Vol 14 (01n02) ◽  
pp. 9-18 ◽  
Author(s):  
K. SERA ◽  
K. TERASAKI ◽  
Y. SAITOH ◽  
J. ITOH ◽  
S. FUTATSUGAWA ◽  
...  
Keyword(s):  
Quantitative Analysis ◽  
Environmental Samples ◽  
Present Method ◽  
Domestic Animals ◽  
Measuring System ◽  
X Rays ◽  
Efficiency Curve ◽  
Elemental Concentrations ◽  
Γ Rays ◽  
Ge Detector

We recently developed and reported a three-detector measuring system making use of a pure-Ge detector combined with two Si ( Li ) detectors. The efficiency curve of the pure-Ge detector was determined as relative efficiencies to those of the existing Si ( Li ) detectors and accuracy of it was confirmed by analyzing a few samples whose elemental concentrations were known. It was found that detection of fluorine becomes possible by analyzing prompt γ-rays and the detection limit was found to be less than 0.1 ppm for water samples. In this work, a method of quantitative analysis of fluorine has been established in order to investigate environmental contamination by fluorine. This method is based on the fact that both characteristic x-rays from many elements and 110 keV prompt γ-rays from fluorine can be detected in the same spectrum. The present method is applied to analyses of a few environmental samples such as tealeaves, feed for domestic animals and human bone. The results are consistent with those obtained by other methods and it is found that the present method is quite useful and convenient for investigation studies on regional pollution by fluorine.

Decay properties of 181Ir

1978 ◽  
Vol 56 (3) ◽  
pp. 321-326 ◽  
Author(s):  
I. M. Ladenbauer-Bellis ◽  
P. Sen ◽  
H. Bakhru
Keyword(s):  
Half Life ◽  
Decay Scheme ◽  
Heavy Ion ◽  
Heavy Ion Reactions ◽  
X Ray ◽  
Decay Properties ◽  
Helium Jet ◽  
Γ Rays ◽  
Ge Detector ◽  
Γ Ray

181Ir activity was produced via the following heavy-ion reactions: 169Tm (16O,4n)181Ir and 169Tm(19F,7n)181Pt (51 s) decaying to 181Ir. The half-life of 181Ir was found to be 4.90 ± 0.15 min. Singles and coincidence γ-ray measurements were performed using 30–40 cm3 Ge(Li) detectors. X-Ray measurements were carried out using an intrinsic Ge-detector. Additionally the helium jet system was used to study the properties of this isotope. The following γ rays were found to belong to the decay of 181Ir: 19.6, 65.3, 93.8, 107.6, 117.9, 123.5, 184.6, 189.9, 227.0, 231.6, 239.2, 309.0, 318.9, 350.5, 352.8, 375.2, 576.5, 700.1, 871.2, 1182.3, 1192.6, 1347.1, 1381.0, 1528.8, 1545.0, 1565.6, 1593.4, 1639.6, 1646.4, 1652.5, and 1714.9 keV. A tentative decay scheme is proposed for 181Ir, verifying levels in l8lOs that have been obtained by reaction work. The proposed decay scheme as well as spin and parity assignments of some of the 181Os levels are discussed.

scholarly journals Production of the 103Pd via Cyclotron and Preparation of the Brachytherapy Seed

2020 ◽  
Author(s):  
Pooneh Saidi ◽  
Mahdi Sadeghi
Keyword(s):  
Optimum Condition ◽  
Nuclear Reaction ◽  
Experimental Measurement ◽  
Radiochemical Separation ◽  
Beam Current ◽  
Published Data ◽  
Excitation Functions ◽  
Resin Beads ◽  
Data Production ◽  
Mev Protons

This study will briefly explain the production of 103Pd via cyclotron for brachytherapy use. The excitation functions of 103Rh(p,n)103Pd and 103Rh(d,2n)103Pd reactions were calculated using ALICE/91, ALICE/ASH, and TALYS-1.2 codes and compared with published data. Production of 103Pd was done via 103Rh(p,n)103Pd nuclear reaction. The target was bombarded with 18 MeV protons at 200 μA beam current for 15 h. After irradiation and radiochemical separation of the electroplated rhodium target, at the optimum condition, 103Pd was absorbed into Amberlite®IR-93 resin. The preparation of the brachytherapy seed, which is loaded by the resin beads, has also been presented. At least, the method to determine the dosimetric parameters for the seed by experimental measurement has been presented.

scholarly journals KARAKTERISTIK PEMISAHAN RADIOLUTESIUM-177/177mLu DAN RADIOITERBIUM-169/175Yb PADA KOLOM RESIN LN-EICHROM

2015 ◽  
Vol 16 (1) ◽  
pp. 1
Author(s):  
Triani Widyaningrum ◽  
Mr Triyanto ◽  
Endang Sarmini ◽  
Umi Nur Sholikhah ◽  
Sunarhadijoso Soenarjo
Keyword(s):  
Nuclear Reaction ◽  
Column Chromatography ◽  
Mobile Phase ◽  
Specific Activity ◽  
High Specific Activity ◽  
Spectrometric Analysis ◽  
Separation Procedure ◽  
Resin Column ◽  
Hno3 Solution ◽  
Separation Characteristic

ABSTRAK KARAKTERISTIK PEMISAHAN RADIOLUTESIUM- 177/177mLu DAN RADIOITERBIUM-169/175Yb PADA KOLOM RESIN LN-EICHROM. Radiolutesium-177Lu keradioaktifan jenis tinggi merupakan salah satu radiolantanida yang banyak digunakan untuk menangani berbagai kasus kanker, namun di Indonesia penggunaan radiofarmaka bertanda 177Lu belum dapat dijanjikan karena teknik produksi radioisotop primernya belum dikuasai. Prospek produksi 177Lu melalui reaksi inti 176Yb (n,g) 177Yb* à 177Lu* + β– dipelajari melalui metode pemisahan matrik 177/177mLu-169/175Yb/176Yb dalam sistem kromatografi kolom resin LN-Eichrom. Profil fraksinasi dan karakteristik pemisahan dipelajari dengan pemeriksaan keradioaktifan dan analisis spektro-metri-g terhadap hasil elusi larutan sasaran pasca iradiasi. Bahan sasaran digunakan 176Yb2O3 alam dan 176Lu2O3 diperkaya. Hasil penelitian menunjukkan bahwa radiolutesium-177/177mLu dapat dipisahkan dari matrik radioiterbium-169/175Yb/natYb melalui sistem kromatografi kolom dengan fase diam resin LN-Eichrom dan fase gerak larutan HNO3, dengan konsentrasi antara 1,5 – 4 M untuk mendapatkan pemisahan yang efektif, selektif dan kuantitatif. Reaksi inti 176Yb(n,g) 177Yb* à 177Lu + β– merupakan model reaksi inti yang perlu dipertimbangkan walau-pun harus melibatkan tahapan pemisahan produk 177Lu dari matrik sasaran Yb pasca iradiasi. Prosedur pemisahan yang dilakukan masih perlu diperbaiki melalui pemilihan jenis dan konsentrasi fase gerak pengelusi yang lebih tepat. ABSTRACT SEPARATION CHARACTERISTIC OF RADIOLUTETIUM-177/177mLu AND RADIOY-TTERBIUM-169/175Yb ON LN-EICHROM RESIN COLUMN. High specific activity radiolutetium-177Lu is one of radiolanthanides that is widely used to handle variety of cancer cases, but in Indonesia the use of 177Lu-labeled-radiopharmaceutical can not be promised yet as the primary radioisotope production techniques have not been mastered.  The  prospect of 177Lu production based on the nuclear reaction of 176Yb (n,g) 177Yb * ® 177Lu * + β– in the BATAN’s G.A. Siwabessy reactor was learned through the separation characteristics of 177/177mLu-169/175Yb /176Yb process matrices in the LN-Eichrom resin column chromatography. The separation and fractionation profiles were characterized by radioactivity measurement as well as g-spectrometric analysis of the eluting post-irradiated target solution. The target materials used were natural 176Yb2O3 and enriched 176Lu2O3. The results showed that radiolutetium-177/177mLu can be separated from the radioiterbium-169/175Yb/natYb matrix by column chromatography system with a stationary phase of LN-Eichrom resin using HNO3 solution as the mobile phase, but the concentration of HNO3 used is a critical variable, between 1.5 - 4 M, to obtain an effective separation selectively and quantitatively. The nuclear reaction of 176Yb (n,g) 177Yb* ® 177Lu + β– using natural Yb2O3 is considered to be better, although it must involve 177Lu product separation stage from the post-irradiated natural Yb target matrix. The presented separation procedure still needs to be improved through the selection of the type and the concentration of the mobile phase used to gain more appropriate elution solvent.

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