scholarly journals Adverse Drug Reactions Study of Antihypertensive Drugs in Primary Care Settings

2021 ◽  
Vol 10 (4) ◽  
Author(s):  
Yeni Farida ◽  
Kharimah Faizathus Tsalatsatun
Keyword(s):  
Primary Care ◽  
Abdominal Pain ◽  
Medical Records ◽  
Adverse Reactions ◽  
Antihypertensive Drugs ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Primary Care Settings ◽  
High Prevalence

Hypertension is one of the high-prevalence diseases in primary care. Failure to achieve the target of blood pressure is affected by non-compliance due to the antihypertensive adverse reactions. This study aims to determine adverse drug reaction (ADR) of antihypertensive drugs in primary care settings. A cross sectional study was conducted in “Sibela” Primary Care in Surakarta on March 2019. Investigators interviewed patients directly and observed supporting data from medical records. Hypertension patients with antihypertensive drugs at least for a month were eligible in this study.  Then, the data were analyzed by the Liverpool algorithm that interpreted in 4 scales: unlikely, possible, probable, and definite.  A total 70 subject were dominated by female (80%). Monotherapy of antihypertensive drugs prescribed to patient in primary care were amlodipine (80%) and captopril (10%). Nine events of ADR were found in hypertension patient. None ADR were doubtful. Possible ADR of amlodipine was drowsiness (5.4%), whereas probable ADR were nausea (3.4%), diuresis (1.8%), and abdominal pain (1.8 %). Definite ADR of captopril was dry mouth (14.3%) and probable ADR was abdominal pain (14.3%). Further investigation regarding the drowsiness, ADR of amlodipine, was needed.

scholarly journals Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Aliasghar Farazi ◽  
Masoomeh Sofian ◽  
Mansoureh Jabbariasl ◽  
Sara Keshavarz
Keyword(s):  
Social Sciences ◽  
Medical Records ◽  
Adverse Reactions ◽  
Cross Sectional Study ◽  
Close Monitoring ◽  
Questionnaire Data ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Antituberculosis Therapy

Background. Antituberculosis multidrug regimens have been associated with increased incidence of adverse drug reactions (ADRs). This study aimed to determine the incidence and associated factors of ADRs due to antituberculosis therapy.Methods. This is a retrospective cross-sectional study on tuberculosis patients who were treated in tuberculosis clinics in Markazi province in Iran. The information contained in the medical files was extracted and entered into the questionnaire. Data was descriptively analyzed by using statistical package for social sciences (SPSS 18).Results. A total of 940 TB patients of 1240 patients’ medical records available in 10 medical offices were included in this study. Of the 563 ADRs found in this study, 82.4% were considered minor reactions and 17.6% were major reactions. No death from antituberculosis ADR was observed. We found that the risk of major ADRs was higher in females (P  value=0.0241), age >50 y (P  value=0.0223), coinfection with HIV (P  value=0.0323), smoking (P  value=0.002), retreatment TB (P  value=0.0203), and comorbidities (P  value=0.0005).Conclusions. This study showed that severe side effects of anti-TB drugs are common in patients who have risk factors of ADRs and they should be followed up by close monitoring.

scholarly journals Reconciliation of medications upon the admission of patients to the cardiology sector of a university hospital

2020 ◽  
Vol 10 (4) ◽  
pp. 0353
Author(s):  
Lorena S. Miranda ◽  
Ana L. Cavalcante ◽  
Rafael M. Pinheiro ◽  
Dayani Galato ◽  
Emília V. Silva
Keyword(s):  
Medical Records ◽  
Medication Reconciliation ◽  
Adverse Reactions ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Medical Prescription ◽  
Cross Sectional ◽  
Cardiology Department ◽  
The University

Introduction: The reconciliation of medications is an important process that impacts on patient safety during the level of care transition, a moment with high discrepancy rates that can lead to adverse reactions. Objective: To analyze the results of medication reconciliation in order to identify discrepancies between the medical prescription and the medications previously used by the patient. Method: A descriptive, cross-sectional study was conducted between May and November 2017 (until the second fortnight of the month), with patients admitted to the cardiology department of the University Hospital of Brasília. Data was collected through interviews with patients, relatives and/or caregivers, and through consultation of the medical records. The reconciliation of medications was performed daily, from Monday to Friday, within 48 hours of the patient’s admission to the unit, through a medication reconciliation form prepared by the author. Results: 90 patients were included in the study and a total of 297 discrepancies were found, 267 (90%) being intentional and 30 (10%), unintentional. Among the unintentional discrepancies, the most frequent was omission of medication in use by the patient (56%). Of the intentional discrepancies, the dosage modifications were more common in 45% of the cases. Conclusion: The reconciliation of medications was a crucial clinical service for the identification and resolution of unintentional discrepancies between previously used medications and hospital medical prescription.

scholarly journals The value of routine screening for cognitive impairment in a primary care setting: a retrospective cross-sectional study

2021 ◽  
Author(s):  
Hailin Qiu ◽  
Janis Chang ◽  
Chih-Peng Chang
Keyword(s):  
Primary Care ◽  
Cognitive Impairment ◽  
Primary Care Clinic ◽  
Cross Sectional Study ◽  
Routine Screening ◽  
Older Individuals ◽  
Sectional Study ◽  
Cross Sectional ◽  
Care Clinic ◽  
Primary Care Settings

Abstract BACKGROUND Cognitive impairment is not uncommon among older individuals but is often underdiagnosed in the primary care settings. Our objective is to identify the prevalence of varying degrees of cognitive impairment in older adults in urban primary care clinics. METHODS This cross-sectional study was undertaken from May to July 2019. The Montreal Cognitive Assessment (MoCA) was administered to participants 65-year and older who were seen during a routine visit to our primary care clinic. The participants were recruited on a sequential basis. The primary outcomes of the study were the MoCA scores, and the level of cognitive impairment, if any, indicated by the scores. RESULTS Out of the 133 participants, 46 (34.6%) scored below the cut-off of 23 out of 30, indicating certain level of cognitive impairment. The mean MoCA score was 23.24. The average age was 75.19 years. Average years of education was 12.6. In our cohort, higher MoCA scores were associated with increased years of education. MoCA scores were not inversely correlated with age. Language proficiency in the MoCA test version administered had significant impact on the MoCA scores. CONCLUSIONS A relatively high prevalence of cognitive impairment was found in our cohort. Further study is required to accurately assess the prevalence of cognitive impairment in general population. However, the findings attest the value of routine screening for cognitive impairment in primary care settings and warrant routine screening of older individuals to help in early detection of mild cognitive impairment.

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