scholarly journals CORRELATION OF MICROALBUMINURIA WITH AGE, DURATION, GLYCATED HEMOGLOBIN, BLOOD SUGAR LEVELS, BLOOD PRESSURE AND RENAL PARAMETERS OF TYPE 2 DIABETES PATIENTS

Author(s):  
Geetha P ◽  
Shanmugasundaram P

  Objectives: Microalbuminuria is the strongest predictor of diabetic nephropathy, which is the main cause of morbidity and mortality. The aim of the study is to determine the prevalence of microalbuminuria in Type 2 diabetes patients and to evaluate the relation between the microalbuminuria and age, duration, glycated hemoglobin (HbA1c), blood sugar levels, blood pressure (BP), and renal parameters of Type 2 diabetes patients.Methods: The prospective study includes 115 patients with Type 2 diabetes, visiting in outpatient diabetes hospital, Chennai. The case reports of the patients diagnosed with blood sugar, HbA1c level BP and renal parameters of Type 2 diabetes patients were recorded and compared with microalbuminuria. Statistical analysis was carried out using student t-test and Pearson correlation.Results: The study revealed that the prevalence of microalbuminuria in this study was 27.82%. Incidence of microalbuminria increases with age, duration of diabetes, blood sugar levels, and hypertension. There is no association of body mass index and sex on the prevalence of microalbuminuria in Type 2 diabetes mellitus. Creatinine clearance has shown a weak negative correlation with microalbuminuria in our study.Conclusion: The present study showed that there is a weak positive correlation of microalbuminuria with blood sugar levels, duration and systolic BP. There is a weak negative correlation of creatinine shows that impairment in the kidney function.

Author(s):  
Orawit Thinnukool ◽  
Pattaraporn Khuwuthyakorn ◽  
Purida Wientong ◽  
Benjamas Suksati ◽  
Nipawan Waisayanand

<p class="0abstractCxSpFirst">As clinical treatments for type-2 diabetes patients using mobile application on smartphones have become more widely practiced, the technology has enabled patients to easily control and monitor their blood sugar levels themselves. Although, the technology development provides more options to improve type-2 diabetes treatment, not all applications developed are suitable for the real treatment as there might be different situations and treatments for different cases.</p><p class="0abstractCxSpMiddle">Research questions occurred while attempting to develop a diabetes mobile application as a supportive learning and self-monitoring tool. These research questions are the followings: How are patients enabled to use the diabetes mobile application effectively? And what are necessary functions of the mobile application for diabetes? The objective of this research are (1) to analysis, design, and development of a type-2 diabetes mobile application (T2DM) (2) to test the application.</p><p class="0abstractCxSpMiddle">The method starts with collecting users’ requirements from diabetes experts, type-2 diabetes patients and their relatives for using the type-2 diabetes literacy-learning tool. Five qualified diabetes experts and five pairs of diabetes patients with their relatives were investigated for gathering users’ requirements that lead to necessary functions for the development. After the T2DM is completely developed, 18 medical staffs and 20 diabetes patients and patient relatives tested the T2DM by using the application.</p><p class="0abstractCxSpLast">Conclusion: When designing the more effective T2DM, developing of necessary functions by users’ involvement ensures that requirements were analyzed and tested. It has been found that the nutrition function is the most significant piece of information for the T2DM, and also the key point of the development. At the same time, the functions for blood sugar recording and information sending are the most supportive and helpful functions for users.</p>


2018 ◽  
Vol 5 (2) ◽  
pp. 163-171 ◽  
Author(s):  
Erni Setiyorini ◽  
Ning Arti Wulandari ◽  
Ayla Efyuwinta

Abstract: Type 2 diabetes is a chronic disease caused by a body that is unable to use insulin effectively. The prevalence of type 2 diabetes increases with age and unhealthy lifestyle. Uncontrolled blood sugar levels type 2 diabetes can trigger a variety of complicationssuch as macroangiopati the complications of large blood vessels that affect blood pressure changes. The purpose of this study was to determine the correlation of blood sugar levels and blood pressure of elderly with Type 2 diabetes. The design of the study was correlation with cross sectional approach. The population was elderly patient with type 2 diabetes which being treated at internal clinic deseases Mardi Waluyo Blitar hospital as much as 300 respondents. The sample was 75 respondents taken by using accidental sampling technique. The statis- tical test used spearman rank. The results of the study showed that the normal blood sugar levels was 41 respondents (54.7%) and normal blood pressure was 42 respondents (56%). Spearman Rank test re- sults indicated there was a significant correlation between blood sugar levels and blood pressure in elderly patients with Type 2 diabetes ( = 0.017) with a coefficient of correlation value was 0.274. There was a correlation between blood sugar levels and blood pressure. The controlled blood sugar levels can maintain blood pressure in the normal range, thus preventing the occurrence of hypertension.Keywords: blood sugar level, blood pressure, elderly, Type 2 diabetesAbstrak: Diabetes melitus tipe 2 merupakan penyakit kronis yang disebabkan oleh tubuh yang tidak mampu menggunakan insulin secara efektif. Prevalensi diabetes tipe 2 meningkat seiring dengan usia dan pola hidup yang tidak sehat. Kadar gula darah diabetes tipe 2 yang tidak terkontrol dapat memicu berbagai macam komplikasi pada penderita diabetes tipe 2, salah satunya terjadi makroangiopati yaitu komplikasi pada pembuluh darah besar sehingga mempengaruhi perubahan tekanan darah. Tujuan dari penelitian ini adalah untuk mengetahui hubungan kadar glukosa darah dengan tekanan darah lansia penderita diabetes tipe 2. Desain dalam penelitian ini adalah korelasi dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah lansia penderita diabetes tipe 2 yang berobat di Poli Penyakit Dalam RSUD Mardi Waluyo Blitar sebanyak 300 responden, sampel yang didapatkan sebanyak 75 responden dengan menggunakan teknik accidental sampling. Uji statistik menggunakan Spearman Rank. Hasil dari penelitian menunjukkan kadar gula darah normal sebanyak 41 responden (54,7%) dan tekanan darah normal sebanyak 42 responden (56%). Hasil uji Spearman Rank menunjukkan terdapat korelasi yang signifikan antara kadar gula darah dan tekanan darah pada lansia penderita diabetes tipe 2 ( = 0.017) dengan koefisien nilai korelasi adalah 0.274. Terdapat hubungan antara kadar gula darah dengan tekanan darah. Kadar gula darah yang terkontrol dapat mempertahankan tekanan darah dalam range normal, sehingga mencegah terjadinya hipertensi.Kata kunci: Kadar gula darah, tekanan darah, lansia, diabetes tipe 2


2020 ◽  
Author(s):  
Kai-Cheng Chang ◽  
Shih-Chieh Shao ◽  
Shihchen Kuo ◽  
Chen-Yi Yang ◽  
Hui-Yu Chen ◽  
...  

Abstract Background Head-to-head comparison of clinical effectiveness between dulaglutide and liraglutide in Asia is limited. This study was aimed to assess the real-world comparative effectiveness of dulaglutide versus liraglutide. Methods We conducted a retrospective cohort study by utilizing multi-institutional electronic medical records to identify real-world type 2 diabetes patients treated with dulaglutide or liraglutide during 2016-2018 in Taiwan and followed up until 2019. Effectiveness outcomes were assessed at every three months in the one-year follow-up. Propensity score techniques were applied to enhance between-group comparability. Significant differences in changes of effectiveness outcomes between treatment groups during the follow-up were examined and further analyzed using mixed-model repeated-measures approaches. Results A total of 1,512 subjects receiving dulaglutide and 1,513 subjects receiving liraglutide were identified. At 12 months, significant HbA1c changes from baseline were found in both treatments (dulaglutide: -1.06%, p<0.001; liraglutide: -0.83%, p<0.001), with a significant between-group difference (-0.23%, 95% confidence interval: -0.38 to -0.08%, p<0.01). Both treatments yielded significant declines in weight, alanine aminotransferase level, and estimated glomerular filtration rate from baseline (dulaglutide: -1.14 kg, -3.08 U/L and -2.08 ml/min/1.73 m2, p<0.01; liraglutide: -1.64 kg, -3.65 U/L and -2.33 ml/min/1.73 m2, p<0.001), whereas only dulaglutide yielded a significant systolic blood pressure reduction (-2.47 mmHg, p<0.001). Between-group differences in changes of weight, blood pressure, and liver and renal functions at 12 months were not statistically significant. Conclusions In real-world T2D patients, dulaglutide versus liraglutide was associated with better glycemic control and comparable effects on changes of weight, blood pressure, and liver and renal functions.


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