scholarly journals EVALUATION OF ANTIOXIDANT, ANTIMICROBIAL, AND ANTIFUNGAL POTENTIAL OF CUCURBITA PEPO VAR. FASTIGATA SEED EXTRACTS

2019 ◽  
pp. 289-293
Author(s):  
ROSHNI RS SONI ◽  
MANOJ BALI
Keyword(s):  
Antibacterial Activity ◽  
Free Radical ◽  
Cucurbita Pepo ◽  
Methanolic Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Seed Extract ◽  
Scavenging Activity ◽  
Antifungal Potential

Objective: The current study aims to study the antioxidant and antimicrobial and antifungal potential of the methanolic extract of Cucurbita pepo var. fastigata seeds (MECS). Methods: Extraction of the seeds has been carried out with solvents of increasing polarity (chloroform, acetone, and methanol) and the phytochemical study of the methanolic extract have been carried out using standard methods. The free radical scavenging activity of all the extracts was evaluated by DPPH and H2O2 methods. Standard disk diffusion method was used to evaluate antibacterial and antifungal activities. Results: Phytochemical evaluation showed the maximum presence of triterpenoids, phenolic compounds, tannins and small amount of Coumarins. Methanolic extract revealed momentous antioxidant activity as compared to chloroform and ethyl acetate extract. Hence, methanolic extract of C. pepo. seeds (MECS) at a dose level of 100, 200 and 300 μg/ml was evaluated for antioxidant potential. Maximum free radical scavenging activity of methanolic seed extract of cucurbita pepo var. fastigata has been found at a dose of 300 μg/ml to be 63±0.16 % by 1,1-diphenyl-2-picryl hydrazyl model and at a value of 78% at 300 μg/ml with H2O2 model. Methanolic extract also showed the presence of antibacterial activity. Conclusion: Presence of phytochemicals in the methanolic extract is responsible for the antioxidant potential. Extracts were investigated for antibacterial activity using the standard disc diffusion assay method against Bacillus subtilis, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa and for the antifungal activities against Aspergillus niger and Candida albicans. The seed extract showed the presence of antibacterial activity, but the antifungal activity was found to be absent in the extract.

scholarly journals COMPARISON OF THREE HERBAL PLANTS FOR BEST FREE RADICAL SCAVENGING ACTIVITY

2017 ◽  
Vol 9 (3) ◽  
pp. 62
Author(s):  
Radha Palaniswamy ◽  
Palghat Raghunathan Padma
Keyword(s):  
Free Radical ◽  
Methanolic Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Oxygen Species ◽  
Leaf Extracts ◽  
Herbal Plants

Objective: Excessive production of reactive oxygen species leads to oxidative stress. Antioxidants can prevent or retard the oxidation caused by free radicals and sufficient intake of antioxidants is supposed to protect against diseases. Candidate play  Methods: The leaf extracts of these plants were exposed to a battery of free radical scavenging assays like DPPH, ABTS, hydrogen peroxide, superoxide and nitric oxide to determine the free radical scavenging activity.Results: It was observed that the Majoranahortensis leaves in methanolic extract showed maximum scavenging activity.Conclusion: Several plants with free radical scavenging activity have been identified, where Majoranahortensis is one such leave.

scholarly journals Antioxidant Screening on the Whole Plant of Cyanthillium cinereum (L) H.Rob

2021 ◽  
Vol 8 (7) ◽  
pp. 458-461
Author(s):  
Mohammed Shihab K. K. ◽  
Rajagopal P. L. ◽  
Nasila K.
Keyword(s):  
Nitric Oxide ◽  
Free Radical ◽  
Methanolic Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Flavonoid Content ◽  
Whole Plant

Methanolic extract of the whole plant of Cyanthillium cinereum (L) H.Robwasevaluated for free radical scavenging activity by using Nitric oxide scavenging activity (NO) and Reduction of 1, 1-Diphenyl -2-Picryl Hydrazyl (DPPH) free radical scavenging activity. Throughout the studies the plant extract showed potent antioxidant activity and the activity was found to be concentration dependent which may be attributed to the high flavonoid content of the plant. Keywords: Cyanthillium cinereum (L) H.Rob, DPPH, NO.

scholarly journals Phytochemical Analysis and Antimicrobial/Antioxidant Activity of Cynodon dactylon (L.) Pers. Rhizome Methanolic Extract

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Samira Savadi ◽  
Mohsen Vazifedoost ◽  
Zohre Didar ◽  
Mohammad Mahdi Nematshahi ◽  
Eisa Jahed
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Cynodon Dactylon ◽  
Methanolic Extract ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Inhibition Zone ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity

A proper use of medicinal plants requires accurate scientific information and understanding of their chemical constituents. The therapeutic effects in the plants are due to the chemical compounds therein. Cynodon dactylon (L.) Pers. of the family Poaceae is a perennial, pan-tropical species of grass which is a well-known traditional medicine and has a renowned position for treatment of many symptoms and diseases. The chemical composition, free radical scavenging activity, and antimicrobial properties of the methanolic extract of C. dactylon rhizomes against selected bacterial and fungal strains were investigated using disk-diffusion method. The results indicated that the major fatty acid structures of C. dactylon methanolic extract were palmitic acid (36.40%), oleic acid (28.26%), and linoleic acid (17.01%). Alpha-tocopherol (151.39 mg·kg−1) and sitosterol (3199.62 mg·kg−1) were the main tocopherols and sterols, respectively. According to the instrumental analysis, the total phenolic compounds of methanolic extract were equal to 917.08 mg·kg−1 and the main compound was hydroquinone (66.89%). Antioxidant activity of the methanolic extract at concentrations of 100–1000 ppm was 9.81–67.87%, which is significantly different from the 200 ppm synthetic antioxidant (BHT) with free radical scavenging activity equal to 48.93% (p<0.05). The antimicrobial study revealed that the methanolic extract of C. dactylon rhizomes was effective against all of the bacterial pathogens and the antibacterial activity increased with an increase in the concentration of extract. Therefore, the largest zone of inhibition was observed against Bacillus cereus (18.3 ± 0.4 mm) and Escherichia coli (16.8 ± 0.5 mm) at 1000 ppm. The highest resistance was observed with Pseudomonas aeruginosa (inhibition zone of 12.8 ± 0.15 mm). Methanolic extract at 200 ppm had no effect against fungus Aspergillus niger. However, at 1000 ppm concentration, an inhibition zone with a diameter of 14.4 ± 0.45 mm was formed.

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