scholarly journals DEVELOPMENT OF EXTRACTIVE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF IRON (III) WITH SCHIFF BASE 2-[(2-HYDROXYPHENYLIMINO) METHYL]-4-NITROPHENOL

2016 ◽  
Vol 8 (4) ◽  
pp. 89 ◽  
Author(s):  
Datta B. Mandhare ◽  
Vasant D. Barhate
Keyword(s):  
Aqueous Solution ◽  
Schiff Base ◽  
Spectrophotometric Method ◽  
Molar Absorptivity ◽  
Maximum Absorption ◽  
Ratio Method ◽  
Pharmaceutical Samples ◽  
Mole Ratio Method ◽  
Ph Range

Objective: A simple spectrophotometric method has been developed for the determination of Iron (III) by using Schiff base 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP].Methods: HPIMNP extracts Fe (III) quantitatively (99.95%) into chloroform from an aqueous solution of pH range 4.0-6.0.Results: The chloroform extracts show maximum absorption at 510 nm (λ max). Beer’s Law is obeyed over the Fe (III) concentration range of 0.5 to 20.0 µg/ml. The Molar absorptivity and Sandell’s sensitivity for Fe–HPIMNP system is 5000 L mol ˉ1 cmˉ1 and 0.011 µg cmˉ2respectively. The composition of extracted species is found to be 1: 3 [Fe-HPIMNP] by Job’s continuous variation and Mole-ratio method. Interference by various ions has been studied.Conclusion: The proposed method is rapid, sensitive, reproducible and accurate and it has been satisfactory applied for the determination of Iron in Pharmaceutical Samples.

scholarly journals Spectrophotometric method for the determination of Captopril in pharmaceutical formulations

2013 ◽  
Vol 10 (3) ◽  
pp. 965-970
Author(s):  
Baghdad Science Journal
Keyword(s):  
Aqueous Solution ◽  
Spectrophotometric Method ◽  
Pharmaceutical Formulations ◽  
Molar Absorptivity ◽  
Maximum Absorption ◽  
Neutral Medium ◽  
Pharmaceutical Tablets ◽  
Colored Product ◽  
Sensitive Spectrophotometric Method

A simple, rapid and sensitive spectrophotometric method has been developed for the determination of captopril in aqueous solution. The method is based on reaction of captopril with 2,3-dichloro 1,4- naphthoquinon(Dichlone) in neutral medium to form a stable yellow colored product which shows maximum absorption at 347 nm with molar absorptivity of 5.6 ×103 L.mole-1. cm-1. The proposed method is applied successfully for determination of captopril in commercial pharmaceutical tablets.

scholarly journals Development of Extractive Spectrophotometric Determination of Rhodium (III) using Schiffs Base as An Analytical Reagent

2021 ◽  
pp. 1101-1105
Author(s):  
Mrs. Ritika Makhijani
Keyword(s):  
Aqueous Solution ◽  
Elemental Analysis ◽  
Spectrophotometric Method ◽  
Molar Absorptivity ◽  
Amyl Alcohol ◽  
Schiff’S Base ◽  
Analytical Reagent ◽  
Ph Range ◽  
Method Show

Rh (III) was determined by simple, sensitive & feasible spectrophotometric method by using analytical reagent N - (o - methoxy benzaldehyde) 2-aminophenol (NOMBAP) . Elemental analysis was used to characterize synthesized Schiff’s base NOMBAP. Rh (III) is extracted quantitatively (99.66%) by NOMBAP into carbon tetra chloride from an aqueous solution having pH range 5.1 – 5.9. An intense peak at 480 nm (λ max) was observed in the extract of n-amyl alcohol. Beer’s law is obeyed over the concentration range 1.0 – 10.0 µg/ml for Rh (III). The molar absorptivity and Sandel’s sensitivity for Rh - NOMBAP system is 8248.23 dm3 mole-1cm-1and 0.08332 μgcm-2 respectively. Mole Ratio & Job’s Continuous Variation and Method show that the extracted species has composition 1:3 (Rh-NOMBAP). Study has been done for interference by various ions. For determination of Rh (III) in alloy the proposed method has been used.

Extractive Spectrophotometric Method for the Determination of Glibenclamide by Ion-Pair Complex in Pure Form and Pharmaceutical Formulation

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
RUAA MUAYAD MAHMOOD ◽  
HAMSA MUNAM YASSEN ◽  
SAMAR , NAJWA ISSAC ABDULLA AHMED DARWEESH ◽  
NAJWA ISSAC ABDULLA
Keyword(s):  
Spectrophotometric Method ◽  
Molar Absorptivity ◽  
Ion Pair ◽  
Pharmaceutical Formulation ◽  
Ratio Method ◽  
Colored Complex ◽  
Colored Product ◽  
Method Of Continuous Variation ◽  
Job's Method

Simple, rapid and sensitive extractive spectrophotometric method is presented for the determination of glibenclamide (Glb) based on the formation of ion-pair complex between the Glb and anionic dye, methyl orange (MO) at pH 4. The yellow colored complex formed was quantitatively extracted into dichloromethane and measured at 426 nm. The colored product obeyed Beer’s law in the concentration range of (0.5-40) μg.ml-1. The value of molar absorptivity obtained from Beer’s data was found to be 31122 L.mol-1.cm-1, Sandell’s sensitivity value was calculated to be 0.0159 μg.cm-2, while the limits of detection (LOD) and quantification (LOQ) were found to be 0.1086 and 0.3292 μg.ml-1, respectively. The stoichiometry of the complex created between the Glb and MO was 1:1 as determined via Job’s method of continuous variation and mole ratio method. The method was successfully applied for the analysis of pharmaceutical formulation.

scholarly journals Spectrophotometric determination of phosphorus in coal and coal ash using bismuth-phosphomobybdate complex

2003 ◽  
Vol 68 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Randjel Mihajlovic ◽  
Natasa Ignjatovic ◽  
Marija Todorovic ◽  
Ivanka Holclajtner-Antunovic ◽  
Vesna Kaljevic
Keyword(s):  
Aqueous Solution ◽  
Ascorbic Acid ◽  
Acid Medium ◽  
Spectrophotometric Method ◽  
Methyl Ketone ◽  
Coal Ash ◽  
Molar Absorptivity ◽  
Stable Complex ◽  
Tolerance Limits

A modified spectrophotometric method using the bismuth phosphomolybdate complex for the determination of phosphorus in coal and coal ash is suggested. Bismuth together with phosphate and molybdate forms a very stable complex in acid medium which turns blue ("molibdenum blue") by reduction with ascorbic acid. The apparent molar absorptivity of PBiMo is 1.66x104 dm3 mol-1cm-1 at 720 nm and 2.10x104 dm3 mol-1cm-1 at 670 nm isobutyl methyl ketone (MIBK). Interference caused by the ions present are within the tolerance limits (?2 %). Beer?s law is obeyed in the for concentration range to 0.6 ?g/mL (aqueous solution) and to 1.2 ?g/mL P (MIBK). The sensitivity of the proposed method is 0.0078 ?g/mL (aqueous solution) and 0.0066 ?g/mL (MIBK).

scholarly journals Sensitive Spectrophotometric Determinations of Paracetamol and Protriptyline HCl Using 3-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Kumble Divya ◽  
Badiadka Narayana ◽  
Majal Sapnakumari
Keyword(s):  
Charge Transfer ◽  
Spectrophotometric Method ◽  
Charge Transfer Complex ◽  
Limit Of Detection ◽  
Pharmaceutical Formulations ◽  
Molar Absorptivity ◽  
Pharmaceutical Samples ◽  
Chromogenic Reagent ◽  
Detection And Quantification

A new spectrophotometric method is developed for the determination of Paracetamol (PCT) and protriptyline HCl (PTP) in pure forms and in pharmaceutical formulations. The experiment involves the use of 3-chloro-7-hydroxy-4-methyl-2H-chromen-2-one as a novel chromogenic reagent for the determination of PCT and PTP. The method is based on the formation of charge transfer complex between the drugs and chromogenic reagent. Beer's law is obeyed in the concentration ranges 10.00–60.00 µg mL−1 for PCT at 545 nm and 40.00–160.00 µg mL−1 for PTP at 468 nm. The molar absorptivity, Sandell, sensitivity, and limit of detection and quantification are also calculated. The method has been successfully applied for the determination of both PCT and PTP in pharmaceutical samples with acceptable results.

scholarly journals 2-Hydroxy-4-n-propoxy-5-bromoacetophenone oxime as an Analytical Reagent for Gravimetric Determination of V(V)

2009 ◽  
Vol 6 (2) ◽  
pp. 303-307 ◽  
Author(s):  
Ambily P. Nair ◽  
J. Christine
Keyword(s):  
Molar Absorptivity ◽  
Ratio Method ◽  
Gravimetric Determination ◽  
Pentavalent Vanadium ◽  
Analytical Reagent ◽  
Gibb’S Free Energy ◽  
The Stability ◽  
Ph Range ◽  
Job's Method

2-Hydroxy-4-n-propoxy-5-bromoacetophenone oxime (HnPBAO) was developed as a new analytical reagent for the gravimetric determination of pentavalent vanadium ion. In the pH range 4.0-6.0, the reagent gave a brown coloured precipitate with V(V). Job’s method and Mole ratio method revealed that the stoichiometry of the complex is 1:1 (metal: ligand). Beer’s law is obeyed up to 20.38 ppm of V(V). Molar absorptivity and Sandells sensitivity at 450 nm were found to be 10.22 × 102L/mol/cm and 0.049 µg/cm2respectively. The stability constant of V(V)-HnPBAO complex is found to be 1.195 × 106. Gibb’s free energy change for complex formation reaction was found to be –8.34 kcal/mol. The reagent can be used for the analysis of vanadium in ferro-vanadium alloys.

scholarly journals Determination of Chromium in Tannery Effluent and Study of Adsorption of Cr (VI) on Saw dust and Charcoal from Sugarcane Bagasses

1970 ◽  
Vol 23 ◽  
pp. 93-101 ◽  
Author(s):  
T. P. Dhungana ◽  
P. N. Yadav
Keyword(s):  
Waste Water ◽  
Aqueous Solution ◽  
Spectrophotometric Method ◽  
Chromium Content ◽  
Chemical Society ◽  
Tannery Effluent ◽  
Saw Dust ◽  
Ph Values ◽  
Ph Range

Spectrophotometric method using diphenylcarbazide as a colour developing reagent has been used to analyze the chromium content in tannery effluent located in Bara and Parsa districts of Nepal and Sirsiya River which is an ultimate drainage of these waste water streams. The adsorption of hexavalent chromium from aqueous solution onto formaldehyde treated sawdust and charcoal of sugarcane begasses has been investigated at various Cr(VI) concentrations of 5-40 mg/L and pH values. From the experimental observations, it has been found that chromium can be removed quantitatively at the equilibrium pH range of around 1 and the adsorption behavior revealed to follow Langmuir and Freundlich adsorption isotherms.Keywords : chromium, diphenylcarbazide, adsorption.DOI: 10.3126/jncs.v23i0.2102Journal of Nepal Chemical Society, Vol. 23, 2008/2009 Page; 93-101

scholarly journals A Rapid and Direct Sensitive Spectrophotometric Method for the Determination of Molybdenum(VI) using Gallacetophenone Phenylhydrazone with Application to Alloy Steel Samples

2011 ◽  
Vol 8 (3) ◽  
pp. 1362-1370 ◽  
Author(s):  
D. Venkataramana Reddy ◽  
P. V. Chalapathi ◽  
A. Varada Reddy
Keyword(s):  
Alloy Steel ◽  
Spectrophotometric Method ◽  
Room Temperature ◽  
Molar Absorptivity ◽  
Analysis Method ◽  
Slope Analysis ◽  
Relative Standard ◽  
Analytical Reagent ◽  
Ph Range

A rapid, sensitive and fairly selective spectrophotometric method has been developed for the determination of molybdenum(VI) using gallacetophenone phenylhydrazone (GPPH) as an analytical reagent. The GPPH forms an orange red species of molybdenum(VI) at a pH range of 3.0-4.0 and the complex is soluble in 20% ethanol. The Mo(VI)-GPPH complex shows maximum absorbance at 375 nm with molar absorptivity and Sandellʼs sensitivity being 1.539x104L/mol cm and 1.5x10-3μg cm-2respectively. The system obeys Beerʼs law in the range of 1.0-6.0 μg/mL. The repeatability of the method was checked by finding the relative standard deviation. The composition of the Mo(VI)-GPPH complex is established as 1:2 by slope analysis method. The instability constant of the complex calculated from Edmond and Birnbaumʼs method is 6.785x10-8at room temperature. The interfering effect of various cations and anions has also been studied. The method has been applied for the determination of Mo(VI) in alloy steel samples.

scholarly journals Spectrophotometric Method for the Determination of Copper (II) in Leafy Vegetable, Soil, Alloys and Pharmaceutical Samples Using 3-Methylthiophene-2-Carbaxaldehyde-3-Thiosemicarbazone (3-MTAT)

2015 ◽  
Vol 51 ◽  
pp. 105-114
Author(s):  
G. Sreenivasula Reddy ◽  
P. Raveendra Reddy
Keyword(s):  
Spectrophotometric Method ◽  
Molar Absorptivity ◽  
Leafy Vegetable ◽  
Pharmaceutical Samples ◽  
Vegetable Soil ◽  
Relative Standard ◽  
Beer's Law ◽  
Beer’S Law ◽  
Determination Of Copper

A highly sensitive spectrophotometric method has been developed for the determination of copper (II) using 3-methylthiophene-2-carbaxaldehyde-3-thilosemicarbazone (3-MTAT) as an analytical reagent. The 3-MTAT forms reddish brown species of copper (II) at a pH range of 5.0-7.0. The Cu (II)-3-MTAT complex shows maximum absorbance at 430 nm, with molar absorptivity and Sandell’s sensitivity being 1.6 x 104 L Mol-1 Cm-1 and 3.6 x 10-3 μg cm-2 respectively. The system obeys Beer’s law in the range of 0.35-3.53mg/L. The regression coefficient of the Beer’s law straight line is 0.338, and the correlation coefficient is 0.999. The detection limit of the method is 0.021 μg mL-1. Most of the common metal ions generally found associated with copper do not interfere. The repeatability of the method was checked by finding the relative standard deviation. The developed method has been successfully employed for the determination of copper (II) in leafy vegetable and pharmaceutical samples and this method was inter comparison of experimental values using AAS.

scholarly journals Determination of paracetamol in pharmaceutical samples by spectrophotometric method

2020 ◽  
Vol 45 (3) ◽  
pp. 37-46
Author(s):  
Chand Pasha
Keyword(s):  
Azo Dyes ◽  
Spectrophotometric Method ◽  
Coupling Agent ◽  
Molar Absorptivity ◽  
Pharmaceutical Samples ◽  
Diazonium Ion ◽  
Hydrolysis Of ◽  
Optimal Reaction ◽  
Basic Standard

It is described the use of 1,3 dinitrobenzene or 2,4 dinitrophenyl hydrazine is used as coupling agent for the spectrophotometric determination of paracetamol. This method is easy and simple based on the reaction of acid hydrolysis of paracetamol to produce p-aminophenol, which in turn reacts with nitrite in acidic standard to form diazonium ion, which is coupled with coupling agent in basic standard to produce azo dyes. The formed dyes follow Beer’s law in the range of 0.8-20.5 mg mL-1 of paracetamol with 1, 3 dinitrobenzene or 0.5-18.4 mg mL-1 of paracetamol with 2,4 dinitrophenyl hydrazine with absorption maxima at 429 nm or 430 nm. The molar absorptivity and Sandell’s sensitivity of paracetamol with 1,3 dinitrobenzene or paracetamol with 2,4 dinitrophenyl hydrazine azo dyes were 1.965×104 L mol-1 cm-1 or 2.776×104 L mol-1 cm-1, and 7.692×10-3 mg cm-2 or 5.698×10-3 mg cm-3 respectively. The dyes formed are stable for more than 12 h. The optimal reaction circumstances and other analytical parameters are evaluated. Interference due to foreign organic compounds have been studied. The method has been effectively applied to the determination of paracetamol in pharmaceutical samples.

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