The impact of mammography screening on breast cancer incidence

2013 ◽  
Vol 2 (2) ◽  
pp. 113-116 ◽  
Author(s):  
Adri C Voogd
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
The Impact

Absence of sustained breast cancer incidence inflation in a national mammography screening programme

2018 ◽  
Vol 26 (1) ◽  
pp. 26-34 ◽  
Author(s):  
Stephen Morrell ◽  
Marli Gregory ◽  
Kerry Sexton ◽  
Jessica Wharton ◽  
Nisha Sharma ◽  
...  
Keyword(s):  
Breast Cancer ◽  
New Zealand ◽  
Cancer Incidence ◽  
Invasive Breast Cancer ◽  
Mammography Screening ◽  
Screening Programme ◽  
Breast Cancer Incidence ◽  
Age Groups ◽  
Incidence Trends ◽  
The Impact

Objective To investigate the impact of population mammography screening on breast cancer incidence trends in New Zealand. Methods Trends in age-specific rates of invasive breast cancer incidence (1994–2014) were assessed in relation to screening in women aged 50–64 from 1999 and 45–69 following the programme age extension in mid-2004. Results Breast cancer incidence increased significantly by 18% in women aged 50–64 compared with 1994–98 (p<0.0001), coinciding with the 1999 introduction of mammography screening, and remained elevated for four years, before declining to pre-screening levels. Increases over 1994–99 incidence occurred in the 45–49 (21%) and 65–69 (19%) age groups following the 2004 age extension (p<0.0001). Following establishment of screening (2006–10), elevated incidence in the screening target age groups was compensated for by lower incidence in the post-screening ⩾70 age groups than in 1994–98. Incidence in women aged ⩾45 was not significantly higher (+5%) after 2006 than in 1994–98. The cumulated risk of breast cancer in women aged 45–84 for 1994–98 was 10.7% compared with 10.8% in 2006–10. Conclusions Increases in breast cancer incidence following introduction of mammography screening in women aged 50–64 did not persist. Incidence inflation also occurred after introduction of screening for age groups 45–49 and 65–69. The cumulated incidence for women aged 45–84 over 2006–10 after screening was well established, compared with 1994–98 prior to screening, shows no increase in diagnosis. Over-diagnosis is not inevitable in population mammography screening programmes.

scholarly journals Divergent Patterns and Trends in Breast Cancer Incidence, Mortality and Survival Among Older Women in Germany and the United States

Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2419
Author(s):  
Lina Jansen ◽  
Bernd Holleczek ◽  
Klaus Kraywinkel ◽  
Janick Weberpals ◽  
Chloé Charlotte Schröder ◽  
...  
Keyword(s):  
Breast Cancer ◽  
United States ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
Relative Survival ◽  
The United States ◽  
The Us ◽  
The Impact

Background: Breast cancer treatment has changed tremendously over the last decades. In addition, the use of mammography screening for early detection has increased strongly. To evaluate the impact of these developments, long-term trends in incidence, mortality, stage distribution and survival were investigated for Germany and the United States (US). Methods: Using population-based cancer registry data, long-term incidence and mortality trends (1975–2015), shifts in stage distributions (1998–2015), and trends in five-year relative survival (1979–2015) were estimated. Additionally, trends in five-year relative survival after standardization for stage were explored (2004–2015). Results: Age-standardized breast cancer incidence rates were much higher in the US than in Germany in all periods, whereas age-standardized mortality began to lower in the US from the 1990s on. The largest and increasing differences were observed for patients aged 70+ years with a 19% lower incidence but 45% higher mortality in Germany in 2015. For this age group, large differences in stage distributions were observed, with 29% (Germany) compared to 15% (US) stage III and IV patients. Age-standardized five-year relative survival increased strongly between 1979–1983 and 2013–2015 in Germany (+17% units) and the US (+19% units) but was 9% units lower in German patients aged 70+ years in 2013–2015. This difference was entirely explained by differences in stage distributions. Conclusions: Overall, our results are in line with a later uptake and less extensive utilization of mammography screening in Germany. Further studies and efforts are highly needed to further explore and overcome the increased breast cancer mortality among elderly women in Germany.

scholarly journals Radiation-Induced Breast Cancer Incidence and Mortality From Digital Mammography Screening

2016 ◽  
Vol 164 (4) ◽  
pp. 205 ◽  
Author(s):  
Diana L. Miglioretti ◽  
Jane Lange ◽  
Jeroen J. van den Broek ◽  
Christoph I. Lee ◽  
Nicolien T. van Ravesteyn ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Digital Mammography ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
Incidence And Mortality ◽  
Radiation Induced

scholarly journals Redefining the impact of nutrition on breast cancer incidence: is epigenetics involved?

2012 ◽  
Vol 25 (1) ◽  
pp. 68-95 ◽  
Author(s):  
Dorothy Teegarden ◽  
Isabelle Romieu ◽  
Sophie A. Lelièvre
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Dna Methylation ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Incidence ◽  
Breast Cancer Incidence ◽  
Dietary Factors ◽  
Transcription Control ◽  
The Impact

Breast cancer incidence is rising worldwide with an increase in aggressive neoplasias in young women. Possible factors involved include lifestyle changes, notably diet that is known to make an impact on gene transcription. However, among dietary factors, there is sufficient support for only greater body weight and alcohol consumption whereas numerous studies revealing an impact of specific diets and nutrients on breast cancer risk show conflicting results. Also, little information is available from middle- and low-income countries. The diversity of gene expression profiles found in breast cancers indicates that transcription control is critical for the outcome of the disease. This suggests the need for studies on nutrients that affect epigenetic mechanisms of transcription, such as DNA methylation and post-translational modifications of histones. In the present review, a new examination of the relationship between diet and breast cancer based on transcription control is proposed in light of epidemiological, animal and clinical studies. The mechanisms underlying the impact of diets on breast cancer development and factors that impede reaching clear conclusions are discussed. Understanding the interaction between nutrition and epigenetics (gene expression control via chromatin structure) is critical in light of the influence of diet during early stages of mammary gland development on breast cancer risk, suggesting a persistent effect on gene expression as shown by the influence of certain nutrients on DNA methylation. Successful development of breast cancer prevention strategies will require appropriate models, identification of biological markers for rapid assessment of preventive interventions, and coordinated worldwide research to discern the effects of diet.

Breast cancer incidence and mortality in the Nordic capitals, 1970–1998. Trends related to mammography screening programmes

2006 ◽  
Vol 45 (5) ◽  
pp. 528-535 ◽  
Author(s):  
Sven Törnberg ◽  
Levent Kemetli ◽  
Elsebeth Lynge ◽  
Anne Helene Olsen ◽  
Solveig Hofvind ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Incidence ◽  
Mammography Screening ◽  
Breast Cancer Incidence ◽  
Incidence And Mortality
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