scholarly journals THE EFFECT OF REMIFENTANIL ON INTUBATION CONDITIONS IN PATIENTS UNDERGOING CAESAREAN DELIVERY UNDER GENERAL ANESTHESIA: COMPARISON OF TWO DOSING REGIMENS

2019 ◽  
pp. 070
Author(s):  
Marija Kutlešić ◽  
Ranko Kutlešić ◽  
Tatjana Ilić-Mostić ◽  
Danka Mostić Stanišić
Keyword(s):  
Cesarean Section ◽  
General Anesthesia ◽  
Endotracheal Intubation ◽  
Neonatal Outcome ◽  
Skin Incision ◽  
Elective Cesarean Section ◽  
Controlled Study ◽  
Intubating Conditions ◽  
Number Of Patients ◽  
Dosing Regimens

The objective of our study was to compare the effects of two remifentanil dosing regimens, used during induction-delivery period of cesarean section, and of remifentanil-free control on maternal intubating conditions and hemodynamic response to endotracheal intubation as well as on neonatal outcome. Seventy seven ASA physical status I-II women with singleton term pregnancy, who were scheduled for elective cesarean section in general anesthesia and have given written informed consent, were enrolled in this prospective, randomized controlled study and divided in three groups: A - 31 patient received 1 µg/kg remifentanil bolus before the induction of anesthesia, followed by 0.15 µg/kg/min remifentanil infusion that was stopped after the skin incision; B - 27 patients received only 1 µg/kg remifentanil bolus; C - 19 patients did not receive remifentanil until the delivery of the baby. Intubating conditions were qualified as excellent, good or poor. Group A had significantly higher number of patients with excellent intubating conditions (p = 0.011); majority of patients with good intubating conditions were in group C (p = 0.017). Systolic, diastolic, main arterial pressure and heart rate raised significantly in group C compared to A and B (p < 0.001). Neonatal outcome did not differ between groups – all neonates were vital with first minute Apgar scores ≥ 8. In conclusion, our dosing regimen of remifentanil 1µg/kg bolus given immediately before the induction followed by 0.15 µg/kg/min interrupted after skin incision provided the best compromise between the achievement of excellent intubating conditions, attenuation of maternal hemodynamic stress response to endotracheal intubation and avoidance of neonatal respiratory depression.

scholarly journals Remifentanil at induction of general anesthesia for cesarean section: Double blind, randomized clinical trial

2013 ◽  
pp. 87-91 ◽  
Author(s):  
Shokoufeh Behdad ◽  
Vida Ayatollahi ◽  
Hamid Harrazi ◽  
Naderali Nazemian ◽  
Najemh Heiranizadeh ◽  
...  
Keyword(s):  
Cesarean Section ◽  
General Anesthesia ◽  
Obstetric Anesthesia ◽  
Skin Incision ◽  
Assisted Ventilation ◽  
Elective Cesarean Section ◽  
Control Group ◽  
Double Blind ◽  
Duration Of Action ◽  
Hemodynamic Variables

Introduction: Remifentanil, with its rapid activity onset and short duration of action, may be more effective than other opioids for providing hemodynamic stability during obstetric anesthesia. However, there is some evidence of adverse effects on neonatal respiratory function. We investigated maternal and fetal effects of remifentanil during cesarean section surgery. Methods: Eighteen women with singleton term pregnancies, and physical class status of I or II as defined by the American Society of Anesthesia (ASA), who were undergoing general anesthesia for semi-elective cesarean section were randomized into two groups (40 in each group) that received either and intravenous bolus of 0.5 µg/kg remifentanil or the same dose of saline as a placebo. Maternal hemodynamic variables and neonatal umbilical artery pH and Apgar score at first and fifth min were evaluated in both groups. Results: Systolic and diastolic blood pressure were significantly lower after tracheal intubation and skin incision in the remifentanil group as compared with the control group (p<0.05). There were no significant differences regarding heart rate between groups at any time (p>0.05). Apgar scores at first and fifth min were not significantly different among groups (p>0.05). No neonate required assisted ventilation or naloxan administration. Conclusion: Remifentanil may be a safe and effective drug for the induction of general anesthesia and surgical stimulation without subsequent neonatal depression.

scholarly journals Comparison of Supreme laryngeal mask airway versus endotracheal intubation for airway management during general anesthesia for cesarean section: a randomized controlled trial

2019 ◽  
Author(s):  
Wei Yu Yao ◽  
Shi Yang Li ◽  
Yong Jin Yuan ◽  
Hon Sen Tan ◽  
Nian-Lin Reena Han ◽  
...  
Keyword(s):  
Laryngeal Mask Airway ◽  
Cesarean Section ◽  
Airway Management ◽  
General Anesthesia ◽  
Endotracheal Intubation ◽  
Airway Device ◽  
Elective Cesarean Section ◽  
Randomized Controlled ◽  
Elective Cesarean ◽  
Reduced Time

Abstract Background The obstetric airway is a significant cause of maternal morbidity and mortality. Endotracheal intubation is considered the standard of care but the laryngeal mask airway (LMA) has gained acceptance as a rescue airway and has been incorporated into the obstetric airway management guidelines. In this randomized controlled equivalence trial, we compared the Supreme LMA (SLMA) with endotracheal intubation (ETT) in managing the obstetric airway during cesarean section. Methods Parturients who underwent elective cesarean section under general anesthesia were randomized to receive either an SLMA or ETT as their airway device. Our primary outcome was first-attempt insertion success. Successful insertion was defined as adequate bilateral air entry with auscultation and the presence of end-tidal carbon dioxide on the capnogram. The first-attempt insertion success rate was compared using the Chi-Square test. Secondary outcomes included time-to-ventilation, seal pressure, ventilation/hemodynamic parameters, occurrence of clinical aspiration, fetal outcomes, and maternal side effects associated with the airway device. Results We recruited 920 parturients (460 SLMA, 460 ETT) who underwent elective cesarean section under general anesthesia. Patient characteristics were similar between the groups. First attempt success was similar (Odds Ratio--ORSLMA/ETA: 1.00 (95%CI: 0.25, 4.02), p = 1.0000). SLMA was associated with reduced time to effective ventilation (Mean Difference--MD -22.96; 95%CI: -23.71, -22.21 seconds) compared to ETT group (p<0.0001). Ventilation parameters, maternal and fetal outcomes were similar between the groups, and there was no aspiration. Conclusions SLMA could be an alternative airway management technique for a carefully selected low-risk obstetric population, with similar insertion success rates, reduced time to ventilation and less hemodynamic changes compared with ETT. Our findings are consistent with the airway guidelines in recommending the second-line use of LMA in the management of the obstetric airway.

scholarly journals Comparison of Supreme laryngeal mask airway versus endotracheal intubation for airway management during general anesthesia for Cesarean section: a randomized controlled trial

2019 ◽  
Author(s):  
Wei Yu Yao ◽  
Shi Yang Li ◽  
Yong Jin Yuan ◽  
Hon Sen Tan ◽  
Nian-Lin Reena Han ◽  
...  
Keyword(s):  
Laryngeal Mask Airway ◽  
Cesarean Section ◽  
Airway Management ◽  
General Anesthesia ◽  
Endotracheal Intubation ◽  
Airway Device ◽  
Laryngeal Mask ◽  
Elective Cesarean Section ◽  
Randomized Controlled ◽  
Reduced Time

Abstract Background The obstetric airway is a significant cause of maternal morbidity and mortality. Endotracheal intubation is considered the standard of care but the laryngeal mask airway (LMA) has gained acceptance as a rescue airway and has been incorporated into the obstetric airway management guidelines. In this randomized controlled equivalence trial, we compared the Supreme LMA (SLMA) with endotracheal intubation (ETT) in managing the obstetric airway during cesarean section. Methods Parturients who underwent elective cesarean section under general anesthesia were randomized to receive either an SLMA or ETT as their airway device. Our primary outcome was first-attempt insertion success. Successful insertion was defined as adequate bilateral air entry with auscultation and the presence of end-tidal carbon dioxide on the capnogram. The first-attempt insertion success rate was compared using the Chi-Square test. Secondary outcomes included time-to-ventilation, seal pressure, ventilation/hemodynamic parameters, occurrence of clinical aspiration, foetal outcomes, and maternal side effects associated with the airway device. Results We recruited 920 parturients (460 SLMA, 460 ETT) who underwent elective Caesarean section under general anesthesia. Patient characteristics were similar between the groups. First attempt success was similar (Odds Ratio--ORSLMA/ETA: 1.00 (95%CI: 0.25, 4.02), p = 1.0000). SLMA was associated with reduced time to effective ventilation (Mean Difference--MD -22.96; 95%CI: -23.71, -22.21 seconds) compared to ETT group (p<0.0001). Ventilation parameters, maternal and fetal outcomes were similar between the groups, and there was no aspiration. Conclusions SLMA could be an alternative airway management technique for a carefully selected low-risk obstetric population, with similar insertion success rates, reduced time to ventilation and less hemodynamic changes compared with ETT. Our findings are consistent with the airway guidelines in recommending the second line use of LMA in the management of obstetric airway.

scholarly journals Comparison of Supreme laryngeal mask airway versus endotracheal intubation for airway management during general anesthesia for cesarean section: a randomized controlled trial

2019 ◽  
Author(s):  
Wei Yu Yao ◽  
Shi Yang Li ◽  
Yong Jin Yuan ◽  
Hon Sen Tan ◽  
Nian-Lin Reena Han ◽  
...  
Keyword(s):  
Laryngeal Mask Airway ◽  
Cesarean Section ◽  
Airway Management ◽  
General Anesthesia ◽  
Endotracheal Intubation ◽  
Airway Device ◽  
Elective Cesarean Section ◽  
Randomized Controlled ◽  
Elective Cesarean ◽  
Reduced Time

Abstract Background The obstetric airway is a significant cause of maternal morbidity and mortality. Endotracheal intubation is considered the standard of care but the laryngeal mask airway (LMA) has gained acceptance as a rescue airway and has been incorporated into the obstetric airway management guidelines. In this randomized controlled equivalence trial, we compared the Supreme LMA (SLMA) with endotracheal intubation (ETT) in managing the obstetric airway during cesarean section. Methods Parturients who underwent elective cesarean section under general anesthesia were randomized to receive either an SLMA or ETT as their airway device. Our primary outcome was first-attempt insertion success. Successful insertion was defined as adequate bilateral air entry with auscultation and the presence of end-tidal carbon dioxide on the capnogram. The first-attempt insertion success rate was compared using the Chi-Square test. Secondary outcomes included time-to-ventilation, seal pressure, ventilation/hemodynamic parameters, occurrence of clinical aspiration, fetal outcomes, and maternal side effects associated with the airway device. Results We recruited 920 parturients (460 SLMA, 460 ETT) who underwent elective cesarean section under general anesthesia. Patient characteristics were similar between the groups. First attempt success was similar (Odds Ratio--ORSLMA/ETA: 1.00 (95%CI: 0.25, 4.02), p = 1.0000). SLMA was associated with reduced time to effective ventilation (Mean Difference--MD -22.96; 95%CI: -23.71, -22.21 seconds) compared to ETT group (p<0.0001). Ventilation parameters, maternal and fetal outcomes were similar between the groups, and there was no aspiration. Conclusions SLMA could be an alternative airway management technique for a carefully selected low-risk obstetric population, with similar insertion success rates, reduced time to ventilation and less hemodynamic changes compared with ETT. Our findings are consistent with the airway guidelines in recommending the second-line use of LMA in the management of the obstetric airway.

Scenario of General Anesthesia for Cesarean Section in Rural Tertiary Care Center in High Altitude Karnali Academy of Health Sciences

2020 ◽  
Vol 16 (3) ◽  
Author(s):  
Ramesh Bhattarai ◽  
Rajiv Shah ◽  
Sita Dhakal ◽  
Pragya Malla ◽  
Srijana Sapkota
Keyword(s):  
Cesarean Section ◽  
General Anesthesia ◽  
High Altitude ◽  
Spinal Anesthesia ◽  
Neonatal Outcome ◽  
Care Center ◽  
Tertiary Care ◽  
Health Sciences ◽  
Tertiary Care Center ◽  
Cord Prolapse

Background: General anesthesia for cesarean section is being less popular for cesarean section in present days but sometime general anesthesia is inevitable. The aim of the study is to assess the trends of general anesthesia, indications, clinical outcome in mother and fetus in high altitude setting of tertiary care center of Nepal. Methods: We conducted descriptive cross-sectional study all cases of cesarean section in Karnali Academy of health Sciences (KAHS) located at high altitude over three years period   in our institute. Data were retrieved from the hospital records during three fiscal year (Jan 1st 2017 to Jan Dec 31st 2019). The record of all the patients who underwent cesarean section under general anesthesia was reviewed for demographic details, indication of general anesthesia, trends for general and spinal anesthesia and maternal and neonatal outcome. Results: Out of total deliveries 2175, 309 (14.2%) cases account for cesarean section. Among them, 52 (17%) required general anesthesia . Eclampsia 19(36%) remain the major indication for General Anesthesia in cesarean section followed by failure of spinal anesthesia number 14 (26%) , cord prolapse six (12%), antepartam haemorrhage five (10%), spinal site infection four (8%), Khiphoscoliosis two(4%), Patients request  two (4%). Use for general anesthesia technique was consistent for three years with slow rise in use of spinal anesthesia . There was no any anesthesia related maternal mortality and nine intraoperative neonatal   Conclusions:  General anesthesia practices are consistently required in rural high-altitude setup. Eclampsia is the commonest indication followed by failure of spinal anesthesia and cord prolapse. Neonatal outcome is still not good.  

To Compare Frequency of Sore Throat in Early Postop period in General Anesthesia and Endotracheal Intubation for Abdominal Surgeries who are given Dexamethasone and Normal Saline

2021 ◽  
Vol 15 (6) ◽  
pp. 1227-1229
Author(s):  
R. Farooqi ◽  
T. Iqbal ◽  
M. S. Mehmood ◽  
Z. Y. Bhatti ◽  
F. Liaquat
Keyword(s):  
General Anesthesia ◽  
Sore Throat ◽  
Endotracheal Intubation ◽  
Normal Saline ◽  
Controlled Study ◽  
Control Group ◽  
Chi Square ◽  
Group I ◽  
Chi Square Test ◽  
Group Ii

Aim: To Compare frequency of sore throat in early post operative period among patients undergoing general anaesthesia and endotracheal intubation for abdominal surgeries who are given dexamethasone and normal saline. Study Design: Randomized controlled study Setting: Department of Anesthesia/ ICU, Sheikh Zayed Hospital, Lahore Duration of study: Six months i.e. 25-09-2009 to 25-03-2010. Methodology: 120 patients undergoing elective general surgery on abdomen were selected. They were divided into two groups. Group I received dexamethasone 8mg (2ml) I/V pre-operatively and group II received 2ml normal saline I/V pre-operatively. Chi square test was used. Visual analogue (VAS) scale was used for recording sore throat. The VAS score ≤4 was considered as no sore throat and VAS scores>4 were considered as the sore throat. Results: Frequency of post-operative sore throat after the first 24 hours following GA and endotracheal intubation was lower in group (I) as compared to the control group (II). Eleven (20%) patients with dexamethasone had post-operative sore throat compared to thirty one (56.3%) patients in control group. (p<0.01). Conclusion: Pre-operative use of dexamethasone was associated with decreased incidence of post-operative sore throat. Keywords: Visual analogue scale (VAS), Post-operative sore throat, general anesthesia

Maternal Hypotension During Elective Cesarean Section and Short-term Neonatal Outcome

2010 ◽  
Vol 30 (3) ◽  
pp. 163-164
Author(s):  
A. Maayan-Metzger ◽  
I. Schushan-Eisen ◽  
L. Todris ◽  
A. Etchin ◽  
J. Kuint
Keyword(s):  
Cesarean Section ◽  
Neonatal Outcome ◽  
Elective Cesarean Section ◽  
Short Term ◽  
Elective Cesarean

scholarly journals Impact of Prophylactic Betamethasone Indication on the Neonatal Outcome in 38-Week Pregnancies Prior to Elective Cesarean Section

2020 ◽  
Vol 10 (10) ◽  
pp. 1396-1401
Author(s):  
Enrique Valdés Rubio ◽  
Pamela Socías ◽  
Javiera Urquieta ◽  
Enrique Valdés M ◽  
Alvaro Sepúlveda-Martínez
Keyword(s):  
Cesarean Section ◽  
Neonatal Outcome ◽  
Elective Cesarean Section ◽  
Elective Cesarean
Sign in / Sign up

Export Citation Format

Share Document