scholarly journals KOMPOSISI PROKSIMAT DAN INDEKS GLIKEMIK NIRA AREN

Biospecies ◽  
2020 ◽  
Vol 13 (2) ◽  
pp. 1-9
Author(s):  
Margaretha Solang ◽  
Yurnia Ningsih N. Ismail ◽  
Wirnangsih D. Uno
Keyword(s):  
Capillary Blood ◽  
Finger Prick

Penelitian ini bertujuan untuk mengevaluasi komposisi proksimat dan nilai indeks glikemik nira aren. Analisis kadar air menggunakan metode oven, protein menggunakan metode semimikro kjeldhal, kadar abu menggunakan metode thermografimetri, dan lemak menggunakan metode ekstruksi langsung dengan alat soxhlet, karbohidrat menggunakan metode by difference, dan gula mengunakan metode Luff schoorl . Analisis indeks glikemik menggunakan perhitungan luas area dibawah kurva menggunakan metode finger-prick capillary blood. Pengukuran kadar glukosa darah pada 10 orang responden yang diberi glukosa murni dan nira aren. Hasil penelitian menunjukkan nira aren mengandung 91,1% air, 0,28% kadar abu, 0,41% protein, 0% lemak, 8,21% karbohidrat dan 0,67% jumlah gula. Rata-rata glukosa darah responden setelah mengkonsumsi glukosa murni dan nira aren pada menit ke-0, 30, 60, 90, 120 yaitu sebagai berikut 93,2 mg/dL, 155,4 mg/dL, 124,2 mg/dL, 93,8 mg/dL, 79,1 mg/dL, dan 81,8 mg/dL, 118,6 mg/dL, 92,6  mg/dL, 74,1 mg/dL, dan 63,7 mg/dL. Nilai indeks glikemik nira aren adalah 35,56 berada pada kategori rendah, sehingga nira aren merupakan minuman alternatif untuk menjaga kadar gula darah.

Ferritin concentrations in plasma from capillary (finger prick) blood and venous blood compared.

1983 ◽  
Vol 29 (5) ◽  
pp. 871-873 ◽  
Author(s):  
L A Mejía ◽  
F E Viteri
Keyword(s):  
Blood Plasma ◽  
Close Association ◽  
Venous Blood ◽  
Capillary Blood ◽  
Ferritin Concentration ◽  
Antecubital Vein ◽  
Finger Prick ◽  
Adults And Children ◽  
Venous Plasma

Abstract Investigating the feasibility and validity of determining plasma ferritin concentration in blood obtained by finger prick, we studied 29 adults (ages 21-49 years) and 35 children (ages 14-66 months). Blood was sampled simultaneously in the same subject from both the antecubital vein (venous blood) and by finger pricking (capillary blood). The plasma was obtained by centrifugation. Ferritin concentration was determined by immunoradiometric analysis. Ferritin concentration in plasma from capillary blood was significantly higher than in venous plasma (p less than 0.01). This difference was more marked in children. The correlation between ferritin from the two blood sources was highly significant (r2 = 0.945 and 0.994 for samples from adults and children, respectively), and the slopes of the respective regression lines in both children and adults were significantly different from 1 (p less than 0.0001). We conclude that, despite the close association between the two procedures, the determination of ferritin concentration in capillary blood plasma overestimates the concentration of ferritin in venous blood plasma.

scholarly journals P342 Correlation of the first lateral flow-based Point of Care test to quantify infliximab and anti-infliximab antibodies in a finger prick sample with the reference ELISA technique

2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S366-S366
Author(s):  
M B Ruiz-Argüello ◽  
J Pascual ◽  
L Del Río ◽  
A Urigoitia ◽  
C Balo Farto ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Point Of Care ◽  
Pearson Correlation ◽  
Capillary Blood ◽  
Lateral Flow ◽  
Real Point ◽  
Infliximab Treatment ◽  
Serum Samples ◽  
Finger Prick ◽  
Elisa Technique

Abstract Background The goal of this study was to validate the use of capillary blood in a real point-of-care (POC) setting for patients under infliximab treatment by using Promonitor Quick lateral flow (LF) tests. Results were compared to the Promonitor ELISA reference technique in serum samples used by centralised laboratories. Methods A prospective, observational study was designed to evaluate the performance of a rapid LF test (Promonitor Quick IFX, Progenika, Spain). 160 infliximab treated rheumatology consecutive patients (400 samples) were recruited in two hospitals in Galicia, Spain. Prior to the infusion, a finger prick sample was obtained and analysed. Anti-infliximab antibodies were also determined with Promonitor Quick ANTI-IFX1-4. Results were read with the automated portable PQreader instrument. Additionally, a serum sample was collected for subsequent comparative analysis with either LF or ELISA tests. Qualitative (positive (PPA) and negative (NPA) agreements) and quantitative (Pearson correlation and bias) performance of the LF test was compared to ELISA, as well as between different specimens following CLSI EP09-A3. Results Overall agreement between Promonitor Quick IFX finger prick and ELISA test was 91% (88% PPA; 100% NPA). The quantitative comparison showed a good correlation (Pearson correlation coefficient: 0.85 and observed bias: 25%) (Table 1). Similar results were also observed when serum was used with either the LF or the ELISA tests (98% overall agreement, 0.91 correlation coefficient; 6% bias) (Table 1). Overall agreements for visual and automated (PQreader) interpretations with Promonitor Quick ANTI-IFX were 99% and 100% for finger prick and serum specimens, respectively (Table 2). Conclusion Promonitor Quick can be used to reliably quantify infliximab in capillary blood samples and results are comparable to those obtained with the reference ELISA technique. The use of the rapid POC test with finger prick will allow clinicians to monitor their patients in a fully decentralized mode to aid in the decision making process. PQreader is a sensitive portable equipment to report drug as well as antibody levels in the patient samples. References

Variation in haemoglobin measurement across different HemoCue devices and device operators in rural Cambodia

2017 ◽  
Vol 70 (7) ◽  
pp. 615-618 ◽  
Author(s):  
Aviva I Rappaport ◽  
Susan I Barr ◽  
Timothy J Green ◽  
Crystal D Karakochuk
Keyword(s):  
Blood Sample ◽  
Capillary Blood ◽  
Blood Samples ◽  
Time Points ◽  
Point Of Use ◽  
Finger Prick ◽  
Capillary Blood Sample ◽  
Haemoglobin Measurement ◽  
Registration Number ◽  
Hb Concentration

Point-of-use haemoglobinometers, such as the HemoCue, are a common method to measure haemoglobin (Hb) concentration in field settings as the device is portable, requires only a small finger-prick capillary blood sample and computes an immediate Hb reading. The aim of this study was to compare Hb measurements across different HemoCue devices and across device operators using capillary blood samples collected from women during a trial in rural Cambodia. We compared mean±SD capillary Hb concentration (g/L) across n=12 different HemoCue Hb 301 devices and across n=9 device operators among 2846 Cambodian women. Significant variability in mean Hb concentration was observed across HemoCue devices (means ranged from 117 to 124 g/L) and across device operators (means ranged from 118 to 124 g/L). This variability is of particular concern when a single HemoCue device or device operator is used at different time points in surveys or research trials.Trial registration numberNCT02481375

scholarly journals Validation of hepatitis C virus RNA detection using capillary blood by finger prick (GenXpert system)—Hepatitis C fingerprick study

2020 ◽  
Vol 27 (7) ◽  
pp. 709-714
Author(s):  
Rob Bielen ◽  
Özgür M. Koc ◽  
Dana Busschots ◽  
Rita Verrando ◽  
Frederik Nevens ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Capillary Blood ◽  
Hepatitis C Virus Rna ◽  
Rna Detection ◽  
Virus Rna ◽  
Finger Prick

scholarly journals Glycaemic index and glycaemic load values of commercially available products in the UK

2005 ◽  
Vol 94 (6) ◽  
pp. 922-930 ◽  
Author(s):  
C. Jeya K. Henry ◽  
Helen J. Lightowler ◽  
Caroline M. Strik ◽  
Hamish Renton ◽  
Simon Hails
Keyword(s):  
Blood Glucose ◽  
Glycaemic Index ◽  
Capillary Blood ◽  
Glucose Response ◽  
Data Set ◽  
Test Food ◽  
Glycaemic Load ◽  
Finger Prick ◽  
The Uk ◽  
Serving Size

The objective of this paper is to provide glycaemic index (GI) and glycaemic load (GL) values for a variety of foods that are commercially available in the UK and to compare these with previously published values. Fasted subjects were given isoglucidic (50 or 25 g carbohydrate) servings of a glucose reference at least two to three times, and test foods once, on separate occasions. For each test food, tests were repeated in at least eight subjects. Capillary blood glucose was measured via finger-prick samples in fasting subjects (0 min) and at 15, 30, 45, 60, 90 and 120 min after the consumption of each test food. The GI of each test food was calculated geometrically by expressing the incremental area under the blood glucose response curve (IAUC) of each test food as a percentage of each subject's average IAUC for the reference food. GL was calculated as the product of the test food's GI and the amount of available carbohydrate in a reference serving size. The majority of GI values of foods tested in the current study compare well with previously published values. More importantly, our data set provides GI values of several foods previously untested and presents values for foods produced commercially in the UK.

scholarly journals COVID-19 serological survey using micro blood sampling

2020 ◽  
Author(s):  
Melissa M. Matthews ◽  
Tae Gyun Kim ◽  
Satoshi Shibata ◽  
Noriko Shibata ◽  
Christian Butcher ◽  
...  
Keyword(s):  
Low Cost ◽  
Positive Control ◽  
Cross Reactivity ◽  
Capillary Blood ◽  
Blood Collection ◽  
Serological Testing ◽  
Serological Survey ◽  
Local Hospital ◽  
Serum Pool ◽  
Finger Prick

AbstractDuring August 2020, we carried out a serological survey among students and employees at the Okinawa Institute of Science and Technology Graduate University (OIST), Japan, testing for the presence of antibodies against SARS-CoV-2, the causative agent of COVID-19. We used a FDA-authorized 2-step ELISA protocol developed by the Krammer Lab (1, 2) in combination with at-home self-collection of blood samples using a custom low-cost finger prick-based capillary blood collection kit. Although our survey did not find any COVID-19 seropositive individuals among the OIST cohort, it reliably detected all positive control samples obtained from a local hospital and excluded all negatives controls. Among our controls, we found strong cross-reactivity of antibodies in samples from a serum pool from two MERS patients in the anti-SARS-CoV-2-S ELISA. Here we show that a centralized ELISA in combination with patient-based capillary blood collection using as little as one drop of blood can reliably assess the seroprevalence among communities. Anonymous sample tracking and an integrated website created a stream-lined procedure. Major parts of the workflow were automated on a liquid handler, demonstrating scalability. We anticipate this concept to serve as a prototype for reliable serological testing among larger populations.

scholarly journals Glycemic Index (GI) Values for Major Sources of Dietary Carbohydrates in Iran

2020 ◽  
Vol 18 (3) ◽  
Author(s):  
Fatemeh Kazemi ◽  
Goodarz Danaei ◽  
Farshad Farzadfar ◽  
Vasanti Malik ◽  
Mahboubeh Parsaeian ◽  
...  
Keyword(s):  
Glycemic Index ◽  
Brown Rice ◽  
Capillary Blood ◽  
Capillary Blood Glucose ◽  
Dietary Carbohydrates ◽  
Blood Samples ◽  
White Rice ◽  
Rye Bread ◽  
Finger Prick ◽  
Staple Foods

Background: The glycemic index (GI) values of staple foods are not available in a standardized method in Iran. Objectives: The aim of this study was to measure the GI values of the major carbohydrate sources in a typical Iranian diet. Methods: Using the international standard method, the GI values were determined for four wheat flatbreads, barley and rye bread, white and brown rice, as well as white and brown rice mixed with lentils. Twelve healthy adults were given 50 g anhydrous glucose three times (as the reference carbohydrate) and the test foods once each throughout the study. Using finger-prick blood samples, capillary blood glucose was measured using a reliable glucometer. The GI was calculated using the trapezoidal method. Results: The GI values of the following types of bread were: Barley 66, Lavash 72, Taftoon 79, Sangak 82, rye 84, and Barbari 99. The GI values for brown and white rice were 65 and 71, respectively. The mixture of brown rice with lentils had a GI value of 55, and the mixture of white rice with lentils had a GI of 79. Conclusions: The most common types of bread and white rice consumed in Iran have high GI values. There is potential to reduce the overall GI values in the Iranian diet by encouraging the consumption of barley bread and brown rice.

scholarly journals Potential of Dried Blood Self-Sampling for CyclosporineC2Monitoring in Transplant Outpatients

2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Alexander Benedikt Leichtle ◽  
Uta Ceglarek ◽  
Helmut Witzigmann ◽  
Gábor Gäbel ◽  
Joachim Thiery ◽  
...  
Keyword(s):  
Therapeutic Drug Monitoring ◽  
Venous Blood ◽  
Dried Blood Spots ◽  
Capillary Blood ◽  
Blood Sampling ◽  
Therapeutic Drug ◽  
Blood Collection ◽  
Blood Samples ◽  
Drug Levels ◽  
Finger Prick

Background. Close therapeutic drug monitoring of Cyclosporine (CsA) in transplant outpatients is a favourable procedure to maintain the long-term blood drug levels within their respective narrow therapeutic ranges. Compared to basal levels (C0), CsA peak levels (C2) are more predictive for transplant rejection. However, the application ofC2levels is hampered by the precise time of blood sampling and the need of qualified personnel. Therefore, we evaluated a newC2self-obtained blood sampling in transplant outpatients using dried capillary and venous blood samples and compared the CsA levels, stability, and clinical practicability of the different procedures.Methods. 55 solid organ transplant recipients were instructed to use single-handed sampling of each 50μL capillary blood and dried blood spots by finger prick using standard finger prick devices. We used standardized EDTA-coated capillary blood collection systems and standardized filter paper WS 903. CsA was determined by LC-MS/MS. The patients and technicians also answered a questionnaire on the procedure and sample quality.Results. TheC0andC2levels from capillary blood collection systems (C0[ng/mL]:114.5±44.5;C2:578.2±222.2) and capillary dried blood (C0[ng/mL]:175.4±137.7;C2:743.1±368.1) significantly(P<.01)correlated with the drug levels of the venous blood samples (C0[ng/mL]:97.8±37.4;C2:511.2±201.5). The correlation atC0wasρcap.-ven.= 0.749, andρdried blood-ven= 0.432; atC2:  ρcap.-ven.= 0.861 andρdried blood-ven= 0.711. The patients preferred the dried blood sampling because of the more simple and less painful procedure. Additionally, the sample quality of self-obtained dried blood spots for LC-MS/MS analytics was superior to the respective capillary blood samples.Conclusions.C2self-obtained dried blood sampling can easily be performed by transplant outpatients and is therefore suitable and cost-effective for close therapeutic drug monitoring.

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