scholarly journals Melanomas malignos do rebordo alveolar na maxila: apresentação de um caso

Author(s):  
Luiz Kosminsky ◽  
Fernando Amaral ◽  
Ageu De Aquino Sales ◽  
Wellington Macedo

A case of primary malignant melanoma on the upper alveolar ridge is reported in a thirsty six year old white woman. A partiar prohthetic denture acted probably as an irritative agent producing prechange of color of alveolor mucosa. Radiumtherapy was done as a palliative treatment. The death due to general metastasis occurred in les e than one yeer. The surgical treatment should be done preferently.

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Shahzad Ahmad ◽  
Mahmoud Abdelghany ◽  
Curtis Goldblatt ◽  
Owen Stark ◽  
Nicholas Masciotra

Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.


2004 ◽  
Vol 171 (2) ◽  
pp. 765-767 ◽  
Author(s):  
DAVID S. DiMARCO ◽  
CONNIE S. DiMARCO ◽  
HORST ZINCKE ◽  
MAURICE J. WEBB ◽  
GARY L. KEENEY ◽  
...  

1991 ◽  
Vol 1 (2) ◽  
pp. 81-87 ◽  
Author(s):  
K. Blessing ◽  
N. M. Kernohan ◽  
I. D. Miller ◽  
A. I. Al Nafussi

From the files of the Scottish Melanoma Group, we have identified 41 cases of vulval malignant melanoma, which represents 1.7% of all the melanomas occurring in women in Scotland, during the period 1979–1989. Thirty-seven were aged 50 years or older with the mean age being 70 years. The average Breslow depth of the lesions was 6.0 mm, with 29 being greater than 3.0 mm in depth. Nineteen cases were polypoidal and 37 were ulcerated. Six patients had radical vulvectomy with lymph node dissection, three had biopsy and palliative treatment, and the majority of the remaining patients had local excision only, with surgical margins of less than 2 cm. The 5-year survival rate (available for 23 patients) is 21.7%, compared to 72% for cutaneous melanoma in females, in general, in the same population. In this series, the survival rate is poor, as the lesions occurred in elderly women and the melanomas were thick at presentation. Surgical treatment appears to have been rather conservative in those who were dead from their disease at 5 years.


2021 ◽  
Vol 161 (1) ◽  
pp. 294-302 ◽  
Author(s):  
Liang Dai ◽  
Zi-Ming Wang ◽  
Zhi-Qiang Xue ◽  
Ming He ◽  
Yong Yuan ◽  
...  

1989 ◽  
Vol 103 (9) ◽  
pp. 887-889 ◽  
Author(s):  
V. Calabrese ◽  
M. Cifola ◽  
R. Pareschi ◽  
A. Parma ◽  
A. Sonzogni

AbstractPrimary mucosal melanomas of the upper aero-digestive tract are uncommon and represent only 1.7 to 3 per cent of all primary melanomas. The most frequent localization are the nasal fossae, the paranasal sinuses and the oral cavity where melanomas most often arise from the palate and alveolar ridge, buccal mucosa, lips, tongue and floor of mouth.The authors describe a case of malignant melanoma of the uvula, review the literature and discuss the aetiology, pathology and diagnostic and therapeutic problems.


1999 ◽  
Vol 56 (6) ◽  
pp. 318-323
Author(s):  
Bösch ◽  
Banic

Die frühe Erkennung und vollständige Exzision ist entscheidend für den Krankheitsverlauf des malignen Melanoms der Haut. Der Sicherheitsabstand bei der chirurgischen Resektion ist heute geringer als vor Jahren und liegt abhängig von der Tumordicke zwischen 1 und 3 cm. Die elektive Lymphadenektomie, das heißt die prophylaktische Entfernung der regionalen Lymphknoten gleichzeitig mit der Nachexzision des Primärtumors, ist umstritten. Sie ist mit einer hohen Komplikationsrate behaftet und bringt nur für eine kleine Subgruppe eine Verbesserung der Überlebensrate. Ein neues Konzept, die Sentinellymphknotenexzision, gewinnt zunehmend an Bedeutung. Durch bestimmte Markierungsmethoden wird derjenige Lymphknoten ermittelt, welcher primär den Lymphabfluß aus dem vom Melanom betroffenen Hautbereich erhält. Dieser Lymphknoten ist repräsentativ für den Metastasenstatus seiner Station. Falls er bei der histologischen Untersuchung eine Metastase zeigt, wird eine vollständige Exzision der regionalen Lymphknotenstation vorgenommen. Diese Methode vermag weitere Hinweise auf die Biologie des Melanoms zu geben und dient als Grundlage für die Wahl von adjuvanten Therapien. Ob sie zu einer Verlängerung der Überlebenszeit führt, ist Gegenstand einer laufenden multizentrischen Studie. Systemische Melanommetastasen haben eine schlechte Prognose. Die chirurgische Resektion von solitären Fernmetastasen hat ihre Bedeutung in der palliativen Behandlung des Melanoms, in Kombination mit adjuvanten Therapien.


ORL ro ◽  
2016 ◽  
Vol 3 (1) ◽  
pp. 44-49
Author(s):  
Bogdan Mocanu ◽  
Daniel Mirea ◽  
Silviu Oprescu ◽  
Anca Vișan ◽  
Mihai Tușaliu ◽  
...  

Introduction. The primitive malignant melanoma of nasal mucosa and paranasal sinus is a rare tumor of uncertain etiology, with unpredictable biologic behavior and bad prognosis. Unlike skin melanomas, there are no risk factors and the disease is frequently manifested in older patients, whose clinical otorhinolaryngology complaints are normally non-specific and ranges from nasal obstruction to rhinorrhea and epistaxis. Unfortunately, this disease is diagnosed basically in advanced stages which makes the surgery difficult. Objective. To report a case of primitive malignant melanoma of nasal mucosa, ethmoid and frontal sinuses, that was diagnosed in 2015. It was performed a subtotal resection in another hospital in 24.08.2015, with a large local reccurence. Report. Our patient was a 78-year-old woman with bilateral nasal obstruction, light epistaxis and unilateral rhinorrhea. The ENT, CT and  MRI exams showed a tumour with important, invasion of the nasal cavity structures (billateral nasal bones, left frontal process of the maxilla, the superior midpoint of the nasal septum, bilateral middle and superior turbinates, left ethmoid and bilateral frontal sinuses). The patient was submited for surgery: total macroscopic resection in the combined endoscopic approach; transnasal and modified lateral rhinotomy with titaniul plates reconstruction of the external nose architecture. Conclusions. Malignant melanomas of nasal mucosa are, in general, diagnosed in advanced stages. Their histological characteristics in the mucosa makes difficult the surgical treatment, which is one of the most efficient options, because they are resistant to chemo and radiotherapy. The early diagnosis and a good surgical treatment plan are the best option for this tumor nowadays.  


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