scholarly journals Etiologies of Hemodynamically Significant Aortic Regurgitation and Coronary Cusp Bending: Evaluation by Transesophageal Echocardiography

2021 ◽  
Author(s):  
Naoki Hoshino ◽  
Akira Yamada ◽  
Meiko Hoshino ◽  
Yuka Kawada ◽  
Sayuri Yamabe ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Transesophageal Echocardiography ◽  
Aortic Regurgitation ◽  
Older Patients ◽  
The Elderly ◽  
Bicuspid Valve ◽  
Aging Society ◽  
Number Of Patients ◽  
Coronary Cusp ◽  
Right Coronary Cusp

Background: While the number of patients with aortic regurgitation (AR) has been increasing in the aging society, its etiologies remain to be fully elucidated. Methods: We studied consecutive 126 patients with chronic moderate or severe AR who underwent TEE. After the study subjects were divided into 2 groups by the age of 65 years, AR etiology was examined in each group. Results: In the older group (n = 85), cusp bending was the most frequent cause of AR (48.2%), and right coronary cusp (RCC) was the most common (90.2%). In the younger group (n=41), bicuspid valve was the most frequent cause (36.5%), and cusp bending was less frequent (16.5%). Multivariate analysis revealed that age was the only factor associated with cusp bending. Conclusion: Cusp bending of RCC was the most frequent etiology of AR in the elderly. Because AR caused by cusp bending has a possibility to be mended by aortic plasty, it is important to detect it by TEE especially in the older patients.

scholarly journals Doubly committed subarterial ventricular septal defect with prolapsed right coronary cusp with moderate aortic regurgitation

2017 ◽  
Vol 10 (4) ◽  
pp. 240
Author(s):  
Redoy Ranjan ◽  
Asit Baran Adhikary ◽  
Mohammad Rashal Chowdhury ◽  
Md. Kabiruzzaman ◽  
Md. Mushfiqur Rahman
Keyword(s):  
Ventricular Septal Defect ◽  
Aortic Regurgitation ◽  
Septal Defect ◽  
Systolic Pressure ◽  
Failure To Thrive ◽  
Ventricular Outflow Tract ◽  
Left Ventricular ◽  
Pulmonary Artery Systolic Pressure ◽  
Coronary Cusp ◽  
Right Coronary Cusp

<p>A 4 year old girl was presented with the respiratory tract infection, breathlessness after taking meal, failure to thrive, abnormal movement of the chest on left side overlying the area of heart and systolic murmur. She developed these symptoms gradually for the last 3.5 years. Echocardiography revealed doubly committed subarterial ventricular septal defect with moderate aortic regurgitation. The size of the ventricular septal defect was 7 x 9 mm at the left ventricular outflow tract. The right coronary cusp of the aortic valve was prolapsed. Left atrium and left ventricle were dilated. The pulmonary artery systolic pressure was 35 mm Hg. The ventricular septal defect was closed with the standard surgical procedure using cardiopulmonary bypass followed by aortotomy and right atriotomy. Immediate post-operative period of this case was uneventful and the patient was discharged on 9<sup>th</sup> post-operative day. Follow-up echocardiography showed no residual ventricular septal defect or aortic regurgitation and the ventricular function was good.</p>

scholarly journals Pathologic and Clinical Characteristics of Elderly Patients With Breast Cancer: A Retrospective Analysis of a Multicenter Study (Anatolian Society of Medical Oncology)

2014 ◽  
Vol 99 (1) ◽  
pp. 2-7 ◽  
Author(s):  
Ali İnal ◽  
Tulay Akman ◽  
Sebnem Yaman ◽  
Selcuk Cemil Ozturk ◽  
Caglayan Geredeli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Retrospective Study ◽  
Elderly Patients ◽  
Older Patients ◽  
The Elderly ◽  
Lymph Node Involvement ◽  
Axillary Lymph ◽  
Breast Cancer Patients ◽  
Number Of Patients ◽  
Er Positive

Abstract There is very little information about breast cancer characteristics, treatment choices, and survival among elderly patients. The purpose of this multicenter retrospective study was to examine the clinical, pathologic, and biologic characteristics of 620 breast cancer patients age 70 years or older. Between June 1991 and May 2012, 620 patients with breast cancer, recruited from 16 institutions, were enrolled in the retrospective study. Patients had smaller tumors at diagnosis; only 15% of patients had tumors larger than 5 cm. The number of patients who had no axillary lymph node involvement was 203 (32.7%). Ninety-three patients (15.0%) had metastatic disease at diagnosis. Patients were characterized by a higher fraction of pure lobular carcinomas (75.3%). The tumors of the elderly patients were also more frequently estrogen receptor (ER) positive (75.2%) and progesterone receptor (PR) positive (67.3%). The local and systemic therapies for breast cancer differed according to age. An association between age and overall survival has not been demonstrated in elderly patients with breast cancer. In conclusion, the biologic behavior of older patients with breast cancer differs from younger patients, and older patients receive different treatments.

scholarly journals Epidemiology of senile spinal diseases: a study based on the Health Insurance Review & Assessment Service database

2021 ◽  
Vol 64 (3) ◽  
pp. 178-184
Author(s):  
Sung Hyun Noh
Keyword(s):  
Health Insurance ◽  
The Elderly ◽  
Spinal Diseases ◽  
Disc Disease ◽  
Fusion Surgery ◽  
Aging Society ◽  
Number Of Patients ◽  
Quitting Smoking ◽  
Aged Society ◽  
Flat Back

According to the Statistics Korea in 2020, the elderly population aged 65 or older accounted for 15.7% of the total population, and by 2025 it will reach 20.3%, which will enter the super-aged society. In an aging society, many degenerative diseases occur with age. In particular, the spine is a structure that acts as a pillar of our body, and as we age, degenerative changes come. Representative senile spinal diseases include disc disease, spinal stenosis, spinal spondylolisthesis, scoliosis, kyphosis, and flat back syndrome. This study intends to examine the epidemiologic characteristics and trends of senile spinal diseases using Korean Health Insurance Review & Assessment Service database from 2010 to 2019. All of the senile spinal diseases have gradually increased in the number of patients and cost over the last 10 years. In addition, the proportion of those aged 60 and over increased among those diagnosed. And fusion surgery and discectomy also increased in the last 10 years, and the treatment cost and ratio of over 60 years old increased. Korea has already become an aging society. So, in the future, senile diseases will increase further, and among them, senile spinal diseases will steadily increase. As a result, the frequency and cost of surgery will continue to increase. Efforts are needed to understand this trend and to prevent senile spinal diseases. For example, regular exercise, proper posture and habits, adequate nutrition, and efforts such as quitting smoking should be required. When these efforts are made, more healthy old life will be achieved.

scholarly journals Severity Indices of Right Coronary Cusp Prolapse and Aortic Regurgitation Complicating Ventricular Septal Defect in the Outlet Septum

2004 ◽  
Vol 68 (2) ◽  
pp. 139-143 ◽  
Author(s):  
Hideshi Tomita ◽  
Yoshio Arakaki ◽  
Yasuo Ono ◽  
Osamu Yamada ◽  
Toshikatsu Yagihara ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Aortic Regurgitation ◽  
Septal Defect ◽  
Coronary Cusp ◽  
Right Coronary Cusp

scholarly journals Isolated Perforation of Left Coronary Cusp after Blunt Chest Trauma

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Rohit Maini ◽  
Razvan T. Dadu ◽  
Daniel Addison ◽  
Luke Cunningham ◽  
Ihab Hamzeh ◽  
...  
Keyword(s):  
Aortic Regurgitation ◽  
Blunt Chest Trauma ◽  
Chest Trauma ◽  
Motor Vehicle ◽  
Motor Vehicle Accident ◽  
Mechanical Valve ◽  
Severe Aortic Regurgitation ◽  
Vehicle Accident ◽  
Coronary Cusp ◽  
Right Coronary Cusp

Left coronary cusp perforation is an extremely rare consequence of blunt chest trauma. A 22-year-old male presented after a motor vehicle accident with dyspnea. Transthoracic echocardiogram (TTE) and transesophageal echocardiogram (TEE) showed moderate to severe aortic regurgitation with prolapsing right coronary cusp. In the operating room he was found to have a left coronary cusp tear near the annulus and an enlarged right cusp. The patient recovered well after successful aortic valve replacement with a mechanical valve. Traumatic aortic regurgitation with left cusp perforation is serious and surgical intervention may be lifesaving if performed timely.

Percutaneous closure of ventricular septal defect using LifeTechTM Konar-MF VSD Occluder: initial and short-term multi-institutional results

2021 ◽  
pp. 1-7
Author(s):  
Masood Sadiq ◽  
Ahmad Usaid Qureshi ◽  
Muhammad Younas ◽  
Sohail Arshad ◽  
Syed Najam Hyder
Keyword(s):  
Ventricular Septal Defect ◽  
Aortic Regurgitation ◽  
Septal Defect ◽  
Defect Closure ◽  
Short Term ◽  
Ventricular Septal Defect Closure ◽  
Coronary Cusp ◽  
The Right ◽  
Right Coronary Cusp

Abstract Background: Transcatheter ventricular septal defect closure remains a complex procedure with potential complications like complete heart block and aortic regurgitation. The ideal device design for such intervention is still evolving. Aim: To assess the safety, efficacy, and short-term outcome of ventricular septal defect closure using LifeTechTM multifunctional (KONAR-MFTM) VSD Occluder. Patients and methods: In a multicenre study, 44 patients with haemodynamically significant, restrictive ventricular septal defects underwent closure with the KONAR-MFTM device from April, 2019 to March, 2020. Clinical, echocardiographic, and angiographic data were collected and reviewed. Patients were followed up at 1, 3, 6, and 12 months. Results: The median age and weight were 8 (1.7–36) years and 20 (11–79) kg. Of 44 patients, 8 (18%) had a high muscular and 36 (82%) had a perimembranous defect, of which 6 had mild prolapse of the right coronary cusp. The median ventricular septal defect size was 8.8 (3.9–13.4) mm. A retrograde approach was adopted in 39 (88.6%) patients. Nine patients (20.5%) had a small residual leak and there was a slight increase in aortic regurgitation in one patient. One device, which embolised to pulmonary artery was retrieved, and the defect was closed with a larger device. At a median follow-up of 13 (5–18) months, the residual leak persisted in 1 (2.3%) patient. Mild aortic regurgitation in one patient remained unchanged. There were no major complications. Conclusion: Percutaneous closure of ventricular septal defect using KONAR-MFTM device is safe and effective in short and midterm follow-up including selected patients with perimembranous defect and mild prolapse of the right coronary cusp.

scholarly journals Diabetes mellitus type 2 in the elderly

2015 ◽  
Vol 125 (1) ◽  
pp. 39-41
Author(s):  
Emilia Rymkiewicz ◽  
Agata Rękas-Wójcik ◽  
Sylwia Milaniuk ◽  
Barbara Mosiewicz ◽  
Grzegorz Dzida
Keyword(s):  
Cardiovascular Events ◽  
Older Patients ◽  
Diabetes Mellitus Type 2 ◽  
Causes Of Death ◽  
Age Groups ◽  
The Elderly ◽  
Advanced Treatment ◽  
Number Of Patients ◽  
Choice Of Treatment

Abstract The number of patients with type 2 diabetes increases along with civilizational development. Advanced treatment methods applied in diabetology and other branches of medicine increase the number of patients. The aim of this work is to present diagnostic and therapeutic problems in elderly people with diabetes. There isa a number of other diseases coexisting with diabetes. These are: hypertension, hyperlipidemia and obesity. The risk of diabetes increases with age and it is related to lowered insulin secretion, worsened absorption and insulin resistance. Diabetes symptoms in older patients differ from those of other age groups. An early diagnosis can minimize the risk of any cardiovascular events, ranked as one of the leading causes of death in elderly patients. The choice of treatment should be adjusted to the particular patient’s needs, avoid any sudden modifications of administered drugs and educating the patients. These are the most important elements of the therapy.

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