scholarly journals Assessment of bronchodilator response by forced oscillation technique in preterm infants with evolving bronchopulmonary dysplasia

2021 ◽  
Author(s):  
Camilla Rigotti ◽  
Emanuela Zannin ◽  
Abedulrhman Abdelfattah ◽  
Maria Luisa Ventura ◽  
Raffaele Dellaca'
Keyword(s):  
Airway Obstruction ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Forced Oscillation ◽  
Lung Mechanics ◽  
Forced Oscillation Technique ◽  
Noninvasive Method ◽  
Bronchodilator Response ◽  
Patient Cooperation ◽  
First Time

Inhaled bronchodilators are often given in preterm infants with evolving or established bronchopulmonary dysplasia. However, it is unclear which patients may benefit from it and when it is the best time to start treatment. The forced oscillation technique (FOT) is a noninvasive method for assessing lung mechanics that proved sensitive to airway obstruction reversibility in children and adults. FOT does not need patient cooperation, which is ideal for infants. Bedside tools for applying FOT in infants during spontaneous breathing and different respiratory support modes are becoming available. This case report illustrates for the first time that FOT has potential value in assessing airway obstruction reversibility in preterm infants, informing which infants may manifest a clinical benefit from the treatment with bronchodilators.

scholarly journals Longitudinal assessment of the lung mechanics of very low birth weight preterm infants with and without bronchopulmonary dysplasia

2015 ◽  
Vol 133 (5) ◽  
pp. 401-407 ◽  
Author(s):  
Rosane Reis de Mello ◽  
Kátia Silveira da Silva ◽  
Anniele Medeiros Costa ◽  
José Roberto de Moraes Ramos
Keyword(s):  
Tidal Volume ◽  
Preterm Infants ◽  
Bronchopulmonary Dysplasia ◽  
Very Low Birth Weight ◽  
Statistical Tests ◽  
Pulmonary Function Tests ◽  
Invasive Mechanical Ventilation ◽  
Lung Compliance ◽  
Lung Mechanics ◽  
Longitudinal Assessment

ABSTRACT CONTEXT AND OBJECTIVE: Prematurity has been correlated with altered lung mechanics. Some infants develop lung injury as a consequence of lung immaturity, invasive mechanical ventilation and exposure to oxygen, thus resulting in bronchopulmonary dysplasia. The aim here was to compare the lung mechanics of preterm infants with and without bronchopulmonary dysplasia during the first year of life. DESIGN AND SETTING: Prospective cohort study in a tertiary-level hospital. METHODS: This study included premature infants at a public hospital who underwent two pulmonary function tests: one at discharge and the other at the corrected age of 4 to 8 months. Tidal volume, lung compliance and lung resistance were measured. Statistical tests were used for comparisons between infants with and without bronchopulmonary dysplasia. RESULTS: 102 children with mean gestational age of 29 ± 2.0 weeks were studied; 17 with bronchopulmonary dysplasia. Lung compliance (0.84 ± 0.29 versus 1.28 ± 0.46; P < 0.001) and tidal volume (6.1 ± 0.94 versus 7.2 ± 1.43; P < 0.01) at discharge were significant lower in children with bronchopulmonary dysplasia than in those without the disease, but no differences were observed at the second test (compliance: 1.53 ± 0.77 versus 1.94 ± 1.01; P = 0.12; and tidal volume: 6.9 ± 1.4 versus 7.3 ± 1.6; P = 0.42). CONCLUSION: Differences in lung mechanics were observed between infants with and without bronchopulmonary dysplasia at hospital discharge but these differences were no longer detected at the final follow-up. The lung mechanics of all the infants improved over this period of time.

Respiratory reactance (Xrs) by Forced Oscillation Technique (FOT) during the first 24h of life in non-intubated preterm infants

2019 ◽  
Author(s):  
Anna Lavizzari ◽  
Chiara Veneroni ◽  
Valeria Ottaviani ◽  
Beretta Francesco ◽  
Claudia Fumagalli ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Forced Oscillation ◽  
Forced Oscillation Technique

scholarly journals Usefulness of the forced oscillation technique in assessing the therapeutic result of tracheobronchial central airway obstruction

2018 ◽  
Vol 56 (3) ◽  
pp. 222-229 ◽  
Author(s):  
Masanori Yasuo ◽  
Yoshiaki Kitaguchi ◽  
Fumiya Kinota ◽  
Makoto Kosaka ◽  
Kazuhisa Urushihata ◽  
...  
Keyword(s):  
Airway Obstruction ◽  
Forced Oscillation ◽  
Forced Oscillation Technique ◽  
Therapeutic Result ◽  
Central Airway Obstruction ◽  
Central Airway

Assessing regional lung mechanics by combining electrical impedance tomography and forced oscillation technique

2018 ◽  
Vol 63 (6) ◽  
pp. 673-681 ◽  
Author(s):  
Chuong Ngo ◽  
Sarah Spagnesi ◽  
Carlos Munoz ◽  
Sylvia Lehmann ◽  
Thomas Vollmer ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Electrical Impedance Tomography ◽  
High Frequency ◽  
Electrical Impedance ◽  
Forced Oscillation ◽  
Pulmonary Function Tests ◽  
Lung Mechanics ◽  
Forced Oscillation Technique ◽  
Impedance Tomography ◽  
Regional Lung

Abstract There is a lack of noninvasive pulmonary function tests which can assess regional information of the lungs. Electrical impedance tomography (EIT) is a radiation-free, non-invasive real-time imaging that provides regional information of ventilation volume regarding the measurement of electrical impedance distribution. Forced oscillation technique (FOT) is a pulmonary function test which is based on the measurement of respiratory mechanical impedance over a frequency range. In this article, we introduce a new measurement approach by combining FOT and EIT, named the oscillatory electrical impedance tomography (oEIT). Our oEIT measurement system consists of a valve-based FOT device, an EIT device, pressure and flow sensors, and a computer fusing the data streams. Measurements were performed on five healthy volunteers at the frequencies 3, 4, 5, 6, 7, 8, 10, 15, and 20 Hz. The measurements suggest that the combination of FOT and EIT is a promising approach. High frequency responses are visible in the derivative of the global impedance index $\Delta {Z_{{\text{eit}}}}(t,{f_{{\text{os}}}}).$ The oEIT signals consist of three main components: forced oscillation, spontaneous breathing, and heart activity. The amplitude of the oscillation component decreases with increasing frequency. The band-pass filtered oEIT signal might be a new tool in regional lung function diagnostics, since local responses to high frequency perturbation could be distinguished between different lung regions.

Sign in / Sign up

Export Citation Format

Share Document