scholarly journals Ipsilateralna operacija primarnog pterigijuma, senzorne ezotropije i konjuktivalni autotransplatant u istom aktu

2003 ◽  
Vol 50 (4) ◽  
pp. 143-145
Author(s):  
Dusica Risovic ◽  
Lj. Nikolic
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Vascular Diseases ◽  
Rectus Muscle ◽  
Bulbar Conjunctiva ◽  
Cytostatic Drugs ◽  
Collagen Vascular Diseases ◽  
Conjunctival Autograft ◽  
The Right

The purpose of this study was to find out whether a conjunctival autograft over the recessed bulbomotor muscle can prevent a recidive of an inflamatory internal pterygium associated with strabismus. The fast growing internal pterygium (crossing corneoscleral limbus of the right eye 3-4mm towards the centre of the cornea) in a 42 years old patient, was removed by superficial keratectomy, while strabismus was corrected by the recession of the internal rectus muscle and covered with an autograft of the upper bulbar conjunctiva. Neither collagen vascular diseases, nor dry eye were present. Horizontal deviation was lessened from +12 to +6, after surgery, and the regrowth of the inflamatory pterygium was not observed during a five years follow up. The risk of the reapperance of pterygium at the site of muscle surgery for strabismus might have been avoided by creating a smooth ocular surface over a thin conjunctival autograft without Tenon's capsule. We believe that conjunctival autograft in such eyes, carrying a higher risk for pterygium regrowth, may help in the avoidance of the use of cytostatic drugs and on their untoward effects.

scholarly journals Tectonic DSAEK for the Management of Impending Corneal Perforation

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Enrique O. Graue-Hernandez ◽  
Isaac Zuñiga-Gonzalez ◽  
Julio C. Hernandez-Camarena ◽  
Martha Jaimes ◽  
Patricia Chirinos-Saldaña ◽  
...  
Keyword(s):  
Dry Eye ◽  
Amniotic Membrane ◽  
Ocular Surface ◽  
Autologous Serum ◽  
Lamellar Keratoplasty ◽  
Corneal Perforation ◽  
Structural Support ◽  
History Of ◽  
The Right ◽  
Corneal Thinning

Purpose. To report a case of severe corneal thinning secondary to dry eye treated with a tectonic Descemet stripping automated lamellar keratoplasty (DSAEK) and amniotic membrane graft.Methods. A 72-year-old man with a history of long standing diabetes mellitus type 2 and dry eye presented with 80% corneal thinning and edema on the right eye and no signs of infectious disease, initially managed with topical unpreserved lubrication and 20% autologous serum drops. Eight weeks after, the defect advanced in size and depth until Descemetocele was formed. Thereafter, he underwent DSAEK for tectonic purposes. One month after the procedure, the posterior lamellar graft was well adhered but a 4 mm epithelial defect was still present. A multilayered amniotic membrane graft was then performed.Results. Ocular surface healed quickly and reepithelization occurred over a 2-week period. Eight months after, the ocular surface remained stable and structurally adequate.Conclusion. Tectonic DSAEK in conjunction with multilayered amniotic graft may not only provide structural support and avoid corneal perforation, but may also promote reepithelization and ocular surface healing and decrease concomitant inflammation.

scholarly journals Use of Systemic Corticosteroids for Reasons Other than Asthma in Subjects with Asthma

Respiration ◽  
2021 ◽  
pp. 1-7
Author(s):  
Keisuke Watanabe ◽  
Nobuyuki Horita ◽  
Yu Hara ◽  
Nobuaki Kobayashi ◽  
Takeshi Kaneko
Keyword(s):  
Adverse Events ◽  
Systemic Corticosteroid ◽  
Multivariable Analysis ◽  
Vascular Diseases ◽  
University Hospital ◽  
Eosinophilic Granulomatosis With Polyangiitis ◽  
Collagen Vascular Diseases ◽  
Systemic Corticosteroids ◽  
Asthma Patients

<b><i>Backgrounds:</i></b> Recent studies have reported increased risks of adverse events from systemic corticosteroids even with only low-dose or short-term use. Some patients with asthma experience complications requiring systemic corticosteroids. However, few studies have examined issues associated with administration of systemic corticosteroids for reasons other than asthma among subjects with asthma. <b><i>Objectives:</i></b> We investigated patterns of systemic corticosteroid exposure for reasons other than asthma in subjects with asthma. <b><i>Method:</i></b> We retrospectively reviewed the records of adult subjects with asthma followed up for &#x3e;1 year at Yokohama City University Hospital from January 1, 2010, to December 31, 2019. We investigated patterns and reasons for systemic corticosteroid use during follow-up. In addition, factors related to systemic corticosteroid use for reasons likely other than asthma were investigated. <b><i>Results:</i></b> Among the 568 subjects with asthma analyzed, 326 (57.4%) had received systemic corticosteroids for some reason. Among those 326 patients, 120 (36.8%) had received systemic corticosteroids for reasons likely other than asthma. Multivariable analysis revealed rheumatoid arthritis, eosinophilic granulomatosis with polyangiitis, other collagen vascular diseases, chronic rhinosinusitis, and malignancy as positively associated with systemic corticosteroid exposure for reasons likely other than asthma in subjects with asthma. <b><i>Conclusions:</i></b> About 40% of systemic corticosteroid use in subjects with asthma was for reasons likely other than asthma. Clinicians should be aware of their asthma patients’ exposures to systemic corticosteroids for nonasthma reasons, to avoid missing adverse events or underestimating the severity of asthma, and to reduce systemic corticosteroid use.

scholarly journals Efficacy of Haridradwayadi Rasakriyanjana in Shushkakshipaka w.s.r to Dry Eye Syndrome- A Case Report

2021 ◽  
pp. 53-57
Author(s):  
Swathi A C ◽  
Naveen B S ◽  
Geetha Kumari ◽  
Ajoy Viswam ◽  
Krishnan Namboodiri
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Clinical Observation ◽  
Objective Assessment ◽  
Dry Eye Syndrome ◽  
Ocular Symptoms ◽  
Corneal Blindness ◽  
Semi Solid ◽  
Inflammatory Syndrome

Tear secretion is an integral component of the ocular surface physiology; when compromised (quantitatively or qualitatively) lead to Dry eye syndrome with several ocular symptoms and ultimately the patient may end up in corneal blindness. The symptoms of Dry eye syndrome are similar to the disease Shushkakshipaka (ocular surface inflammatory syndrome) in Ayurveda. Vata & Pitta vitiation as per Ayurveda viewpoint are the major contributing pathological factors in its manifestation. Although a number of researches have been carried out and are still continuing, no curative treatment has been achieved yet. This paper aims to establish the efficacy of Haridradwayadi Rasakriyanjana during the clinical observation of a 55 years old female subject who was diagnosed with Shushkakshipaka. She was administered with the drug Haridradwayadi Ghrita in the form of Rasakriyanjana (semi-solid collyrium) drops topically for 30 days, by using subjective and objective assessment criteria which showed a significant result. After the treatment, majority of the symptoms reduced considerably and during the follow up concluded that there was no aggravation of the same.

scholarly journals TREATMENT FOR CONJUNCTIVOCHALASIS: A COMBINED APPROACH UTILIZING RADIOFREQUENCY CAUTERIZATION AND THERMALIDTM PROCEDURE

2021 ◽  
Vol 4 (1) ◽  
pp. e1-e10
Author(s):  
Liem Nguyen ◽  
Edward Jaccoma
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Symptomatic Relief ◽  
Retrospective Chart Review ◽  
Signs And Symptoms ◽  
Meibomian Gland ◽  
Significant Clinical Improvement ◽  
Pre Treatment ◽  
Tear Meniscus Height

BackgroundDry Eye Disease (DED) and related ocular surface diseases have multiple etiologies, but two of the most prevalent are Meibomian Gland Dysfunction (MGD) and Conjunctivochalasis (CCH). This study examines a customizable two-step approach utilizing radiofrequency to treat these two commonly coexisting condi-tions and provide patients with relief from DED signs and symptoms. Study DesignAn IRB approved retrospective chart review of 25 consecutively treated patients was conducted. Patients were included if they presented with DED symptoms and were treated with a combination treatment approach to improve both MGD and CCH, with pre- and post-treatment dry eye metrics outlined below. Follow-up visit information was compared to pre-treatment baseline to evaluate the efficacy and safety of treatment. ResultsStatistically significant results were observed in a decrease in symptoms as evaluated by the primary endpoints of the Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire and an increase in the number of Meibomian Glands Yielding Liquid Secretion (MGYLS). Tear Meniscus Height also saw statistically significant improvement while Non-invasive Tear Break-Up Time (NTBUT) and Schirmer’s saw minor progress. Clinical evaluation and ocular surface photographs showed marked improvement in CCH with minimal observed side effects during post-operative follow-up visits. ConclusionA two-step approach utilizing a radiofrequency device to treat dry eye symptoms provides significant clinical improvement and symptomatic relief for a broad spectrum of patients who had received a variety of prior treatments for DED.

scholarly journals Examination for Dry Eyes

2021 ◽  
Author(s):  
Tri Wahyu
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Signs And Symptoms ◽  
Eye Disease ◽  
Initial Examination ◽  
Laboratory Equipment ◽  
Dry Eyes ◽  
Potential Damage

Dry eye disease (DED) is a multifactorial disease of tears and ocular surface that results in various symptoms with the potential damage to the ocular surface. It can range from mild to severe signs and symptoms and may affect patient’s quality of life. Various techniques and methods have been developed to evaluate DED for initial examination or regular follow up. The simple evaluations that can be performed in clinic include eyelid examination, tear break-up time, and ocular surface stainings; while the advanced ones may require certain devices or laboratory equipment. Careful and thorough examinations are important to guide the clinician to assess and evaluate dry eye.

scholarly journals Isolated bilateral congenital lacrimal gland agenesis presenting as dry eye in childhood: a rare entity

2020 ◽  
Vol 17 (1) ◽  
pp. 74-77
Author(s):  
Anitha Venugopal ◽  
Sowmya Peri ◽  
Ravi Chandra ◽  
Meenakshi Ravindran ◽  
Rengappa Ramakrishnan
Keyword(s):  
Salivary Glands ◽  
Dry Eye ◽  
Lacrimal Gland ◽  
Ocular Surface ◽  
Vitamin Supplementation ◽  
Bulbar Conjunctiva ◽  
Eye Drops ◽  
Rare Entity ◽  
Permanent Occlusion ◽  
Functional Vision

We report the case of a 1-year-old child who presented with complaints of redness and defective vision since birth. The child had no systemic abnormalities. On examination, complete keratinization of the bulbar conjunctiva and cornea was noted with dry, lustreless and irregular surface. Corneal sensation was intact. Orbital MRI revealed bilateral agenesis of the lacrimal gland with normal salivary glands. The child was given vitamin supplementation, cyclosporine eye drops along with lubricants and tape tarsorrhaphy in the night. Permanent occlusion of both the lower puncta was done. There was decreased ocular surface congestion, with frequent wetting of the ocular surface, which continued in the months to follow. We present a case of isolated bilateral lacrimal gland agenesis with normal salivary glands, a rare cause of dry eye in children. An early diagnosis and conservative management can help in maintaining functional vision in such cases.

scholarly journals Isolated rectus muscle rupture following trauma

2016 ◽  
Vol 7 (2) ◽  
pp. 182-185 ◽  
Author(s):  
Halil Hüseyin Çağatay ◽  
Metin Ekinci ◽  
Şendoğan Ulusal ◽  
Mehmet Ersin Oba ◽  
Zeliha Yazar
Keyword(s):  
Treatment Options ◽  
Rectus Muscle ◽  
Inferior Rectus ◽  
Primary Position ◽  
Initial Surgery ◽  
Muscle Rupture ◽  
The Right ◽  
Periorbital Swelling ◽  
Cover Test

Background: Isolated rectus muscle ruptures are rare ophthalmic emergencies which may result in permanent diplopia. Objective: To highlight updates on clinical features, surgical treatment options and potential complications for isolated inferior rectus ruptures. Case: A 39-year-old man came to our emergency department complaining of diplopia and upward deviation of the right eye after experiencing an animal injury. Extraocular movements were limited in the right eye in the downgaze position. The alternate prism and cover test, both at distance and near testing, showed hypertropia of 40 prism diopters (PD) of the right eye. The right eye had periorbital swelling and conjunctival haematoma. An inferior rectus rupture repair was performed under local anesthesia and monitored sedation. Follow-up examination revealed a 20 PD hypertropia, causing diplopia in all gazes. A second surgical intervention was planned six months after the initial surgery, an inferior rectus 6 mm resection was performed, after which orthophoria was achieved in the primary position both at distance and near testing. 

Pterygium Surgery with Conjunctival Autograft Fixation Using Bipolar Electrocauterization

2020 ◽  
pp. 112067212096548
Author(s):  
Fernando Quadros Costa ◽  
Ricardo Quadros Costa ◽  
José Bonifácio Barbosa ◽  
José Álvaro Pereira Gomes
Keyword(s):  
Outcome Measure ◽  
Intraoperative Complications ◽  
Case Series ◽  
Bulbar Conjunctiva ◽  
Complication Rates ◽  
Safe Procedure ◽  
Conjunctival Autograft ◽  
Pterygium Surgery ◽  
The Mean

Purpose: To report a case series of pterygium surgery with conjunctival autograft fixation using bipolar electrocautery. Design: A noncomparative, retrospective, interventional case series of pterygium surgery with follow-up longer than 12 months to assess recurrence and other complication rates. Participants: Fifty-six eyes of 37 patients were treated between April 2011 and January 2018, either for primary ( n = 53 cases) or recurrent ( n = 3 cases) pterygia. Intervention: After pterygium excision, free conjunctival grafts from the inferior bulbar conjunctiva of the same eye were harvested and fixated with the use of bipolar electrocautery. Main outcome measure: Recurrence of the pterygium and complications. Results: The mean follow-up was 41 months (range 12 to 81 months). There were no intraoperative complications. Recurrence of the lesion was seen in three eyes (5.36%). There were no other postoperative complications such as graft detachment, or formation of dellen or granulomas. Conclusion: Conjunctival autograft fixation using bipolar electrocautery seems to be a fast, costly and safe procedure that can be applied in most cases of pterygium surgery.

scholarly journals The Influence of Work Environment Factors on the OcularSurface in a One-Year Follow-Up Prospective Clinical Study

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 392
Author(s):  
Edyta Chlasta-Twardzik ◽  
Aleksandra Górecka-Nitoń ◽  
Anna Nowińska ◽  
Edward Wylęgała
Keyword(s):  
Clinical Study ◽  
Dry Eye ◽  
Ocular Surface ◽  
Negative Impact ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Prospective Clinical Study ◽  
Air Humidity ◽  
Relative Air Humidity

The purpose of this study was to assess the effect of environmental working conditions on the symptoms and signs of dry eye disease and to examine whether and how those conditions impact the ocular surface. Methods: This single-center, prospective clinical study with a 1-year follow-up included 150 patients. The following parameters were evaluated: non-invasive keratograph break-up time (NIKBUT), tear meniscus height (TMH), and conjunctival and limbal hyperemia. We also performed staining of the surface of the eye for simulated fluorescein images, Schirmer’s test I, assessment of Meibomian gland dysfunction (MGD), and an Ocular Surface Disease Index (OSDI) questionnaire. Results: In the OW (office workers) group, in people working > 4 h at the computer, the NIKBUT before work and the Schirmer test results were statistically significantly lower than in people working <4 h. The conjunctival hyperemia result before work was statistically significantly higher for people working >4 h at a computer in both groups and after work in the MW (medical workers) group. Low relative air humidity in the building and air-conditioned rooms negatively affects the tear film, causing the symptoms of dry eye disease. At the 1-year follow-up, there was a statistically significant reduction in conjunctival and limbal hyperemia in the OW group as well as a statistically significant reduction in TMH at the first examination before and after work, and in the second examination after 1 year in both groups. Conclusions: Environmental factors such as reduced relative air humidity, increased air temperature, and decreased illumination have a negative impact on the ocular surface.

Should we care about the ocular surface in the anophthalmic patient?

2021 ◽  
pp. 112067212110488
Author(s):  
Giulio Volpe ◽  
Maria De Piano ◽  
Giacomilde Mazzone ◽  
Alessandra Micera ◽  
Stefano Bonini ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Dry Eye ◽  
Ocular Surface ◽  
Bulbar Conjunctiva ◽  
Type I ◽  
Ocular Prosthesis ◽  
Fellow Eye ◽  
Markers Of Inflammation ◽  
Conjunctival Inflammation ◽  
Anophthalmic Socket

Purpose: To assess clinical and biomolecular changes of the conjunctival epithelium in anophthalmic patients wearing an ocular prosthesis. Methods: Thirty-five unilateral anophthalmic patients were enrolled. Patients with blepharitis, lid abnormalities, and topical/systemic medication affecting the ocular surface were excluded. Symptom Assessment in Dry Eye (SANDE) questionnaire and tear function test (Schirmer Test Type I) were recorded. Conjunctival inflammation and meibomian gland dysfunction (MGD) were graded in the anophthalmic side and fellow eye. Impression cytology sampling of the upper, lower tarsal, and posterior/bulbar conjunctiva from the anophthalmic socket were collected and compared to healthy controls. Results: Patients had significantly higher SANDE ( p < 0.001), Schirmer I test ( p = 0.004), conjunctival inflammation ( p < 0.001), and MGD scores ( p < 0.001) on the anophthalmic side compared to the fellow eye. Mucin 5AC, inflammatory markers (MMP-9, ICAM-1) expression ( p < 0.001), and response to oxidative stress (NRF2-KEAP1 signaling pathway) ( p < 0.05) were significantly upregulated in the posterior conjunctival surface in the anophthalmic socket. Conclusions: Anophthalmic patients complained of more pronounced dry eye symptoms and presented more significant signs of inflammation and MGD on the anophthalmic side. The bulbar conjunctiva, behind the prosthesis, showed more significant hyperexpression of mucins, markers of inflammation, and increased response to oxidative stress compared to the tarsal conjunctiva. Patients wearing ocular prosthesis had signs of inflammation resembling dry eye disease.

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