Efficacy of Haridradwayadi Rasakriyanjana in Shushkakshipaka w.s.r to Dry Eye Syndrome- A Case Report

Tear secretion is an integral component of the ocular surface physiology; when compromised (quantitatively or qualitatively) lead to Dry eye syndrome with several ocular symptoms and ultimately the patient may end up in corneal blindness. The symptoms of Dry eye syndrome are similar to the disease Shushkakshipaka (ocular surface inflammatory syndrome) in Ayurveda. Vata & Pitta vitiation as per Ayurveda viewpoint are the major contributing pathological factors in its manifestation. Although a number of researches have been carried out and are still continuing, no curative treatment has been achieved yet. This paper aims to establish the efficacy of Haridradwayadi Rasakriyanjana during the clinical observation of a 55 years old female subject who was diagnosed with Shushkakshipaka. She was administered with the drug Haridradwayadi Ghrita in the form of Rasakriyanjana (semi-solid collyrium) drops topically for 30 days, by using subjective and objective assessment criteria which showed a significant result. After the treatment, majority of the symptoms reduced considerably and during the follow up concluded that there was no aggravation of the same.

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Dry Eye Syndrome: Severe Ocular Surface Inflammatory Syndrome Post LASIK Caused by Blepharitis

Difficult and Complicated Cases in Refractive Surgery ◽

10.1007/978-3-642-55238-0_46 ◽

2014 ◽

pp. 213-215

Author(s):

Jorge L. Alió ◽

Dominika Wróbel ◽

Alessandro Abbouda

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Dry Eye Syndrome ◽

Inflammatory Syndrome

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Efficacy of cyclosporine 0.05% in patients with dry eye syndrome

International Journal of Community Medicine and Public Health ◽

10.18203/2394-6040.ijcmph20193451 ◽

2019 ◽

Vol 6 (8) ◽

pp. 3339

Author(s):

Jitender Phogat ◽

Ritesh Verma ◽

Manisha Rathi ◽

Sumit Sachdeva ◽

Latika Pandey

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Tear Film ◽

Dry Eye Syndrome ◽

Paper Test ◽

Inflammatory Reactions ◽

Ocular Symptoms ◽

Body Sensation ◽

Ocular Discomfort ◽

Breakup Time

Background: An even and smooth ocular surface is vital for the functioning and comfort of the eyes. Dry eye is a group of disorders of the tear film which is due to either decreased production or increased evaporation and is associated with symptoms of ocular discomfort. Smoking and drugs have been suggested as risk factors in various studies. Cyclosporine has been shown to reduce the cell-mediated inflammatory reactions associated with the inflammatory ocular surface disease.Methods: 50 eyes of 25 patients suffering from dry-eye syndrome were included in this study. Three major ocular symptoms of dry eye i.e., ocular pain, burning, and foreign body sensation were studied in this study. Each symptom was given a score from 0 to 1 so that the ocular symptoms were given a score from 0 to 3.Results: There was a significant reduction in ocular symptoms score (OSS) 2.25 before treatment to 0.6 after 3 months of treatment (p=0.01). In addition, the Schirmer's paper test scores improved from 1.23 mm to 5.91 mm, which is significantly different (p=0.001). The tear film breakup time also improved from 5.49s to 9.86s.Conclusions: Cyclosporine 0.05% has been established to be effective and safe in our study.

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Ayurvedic Management of Severe Dry Eye Syndrome & Complications: A Case Study

AYUSHDHARA ◽

10.47070/ayushdhara.v8i5.815 ◽

2021 ◽

pp. 3542-3546

Author(s):

Preeti Pahwa ◽

Ashu Vinaik ◽

Priya Patel ◽

Jasmine Kaur

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Tear Film ◽

Dry Eye Syndrome ◽

Industrialized Countries ◽

Ocular Symptoms ◽

Film Instability ◽

Surface Disorder ◽

Ocular Surface Inflammation

Dry eye syndrome (DES) is a common condition that causes pain and can lead to vision problems. Modern living has given rise to a massive increase in the incidence of vision threatening dry eye disease, around 10-30% of population living in industrialized countries suffer from dry eye syndrome (DES). According to Second International Dry Eye Workshop (DEWS II) in 2017 offered dry eye as it is a multifactorial ocular surface disorder defined by a loss of tear film homeostasis and ocular symptoms, in which tear film instability and hyperosmolarity, as well as ocular surface inflammation and injury, play a part in the etiology. If it is not controlled with in time it can lead to corneal blindness. Ayurveda proposes a comprehensive systemic & topical strategy in the treatment of dry eye syndrome, in contrast to the available modern medical treatment. In this publication, a case study of a Shushkakshipaka with many complications who was treated with dynamic Ayurvedic treatments & after continuous efforts patient got very significant results is being discussed here.

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Ocular Comorbidities in Rosacea: A Case-Control Study Based on Seven Institutions

Journal of Clinical Medicine ◽

10.3390/jcm10132897 ◽

2021 ◽

Vol 10 (13) ◽

pp. 2897

Author(s):

Yu Ri Woo ◽

Minah Cho ◽

Hyun Jeong Ju ◽

Jung Min Bae ◽

Sang Hyun Cho ◽

...

Keyword(s):

Dry Eye ◽

Case Control Study ◽

Matched Control ◽

Case Control ◽

Dry Eye Syndrome ◽

Data Set ◽

Ocular Symptoms ◽

Inflammatory Dermatosis ◽

Control Study ◽

Surface Changes

Rosacea is a facial inflammatory dermatosis that is linked with various systemic illnesses. With regards to the eye, rosacea patients have been described to manifest ocular surface changes, such as blepharitis and conjunctivitis. However, studies that examine the association of rosacea with a wider array of ocular diseases are limited. Thus, our aim was to identify the range of ocular comorbidities in the Korean patient population and create a reference data set. A multi-institutional, case-control study was conducted, where 12,936 rosacea patients and an equal number of sex- and age-matched control subjects were extracted over a 12-year period. We were able to discover a notable association between rosacea and blepharitis (adjusted odds ratio (aOR) 3.44; 95% confidence interval, 2.71–4.36, p < 0.001), conjunctivitis (aOR 1.65; 95% CI, 1.50–1.82, p < 0.001), glaucoma (aOR 1.93; 95% CI, 1.70–2.20, p < 0.001), dry eye syndrome (aOR 1.89; 95% CI, 1.70–2.09, p < 0.001), and chalazion (aOR 3.26; 95% CI, 1.41–7.57, p = 0.006) from logistic regression analysis. Female subjects and individuals younger than 50 exclusively showed higher odds for chalazion. Our study suggests that ocular comorbidities (i.e., glaucoma, dry eye syndrome, and chalazion as well as blepharitis and conjunctivitis) are more prevalent among Koreans with rosacea. Clinicians should proactively check ocular symptoms in rosacea and employ joint care with an ophthalmologist in cases of need.

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Dry Eye Syndrome-Related Quality of Life in Glaucoma Patients

European Journal of Ophthalmology ◽

10.1177/112067210901900409 ◽

2009 ◽

Vol 19 (4) ◽

pp. 572-579 ◽

Cited By ~ 78

Author(s):

Gemma Caterina Maria Rossi ◽

Carmine Tinelli ◽

Gian Maria Pasinetti ◽

Giovanni Milano ◽

Paolo Emilio Bianchi

Keyword(s):

Quality Of Life ◽

Dry Eye ◽

Ocular Surface ◽

Cross Sectional Study ◽

Dry Eye Syndrome ◽

Control Group ◽

Ocular Surface Disease Index ◽

Symptom Scale ◽

Cross Sectional

Purpose To verify the presence of dry eye syndrome (DES) in treated patients with glaucoma and to analyze DES's impact on the patients' quality of life (QOL) versus the control group. Methods In this observational cross-sectional study, 61 patients were enrolled at a clinical practice. Patients were divided into three groups by number of glaucoma drops instilled per day (G1=1 drop/day, G2=2 drops/day, G3=3 drops/day). A control group of 20 subjects was also selected (G0). All subjects were submitted to a complete ocular examination (including tear function and ocular surface status) and completed the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ), Glaucoma Symptom Scale (GSS) questionnaire, and Ocular Surface Disease Index (OSDI). DES was defined as presence of punctate keratitis and decreased break-up time. Statistical analysis was performed applying the Kruskal-Wallis analysis of variance and Mann-Whitney U tests (to compare median values between groups) as well as the χ2 and Fisher test (to verify significant differences). Results A total of 40% of G3 and 39% of G2 patients presented DES versus 11% of G1 and 5% of G0 (p=0.01). QOL was significantly influenced and altered (NEI-VFQ 25 total mean and GSS total mean and symptoms average: p=0.0085, p=0.006, and p=0.03, respectively). OSDI pointed out differences by group: 26% of G2 and 15% of G3 presented moderate OSDI and 15% of G3 and 8.7% of G2 severe OSDI (p>0.05). Conclusions Patients with topically treated glaucoma present DES more often than a similar control group (p=0.01). The presence of DES negatively influences the patient's QOL. The patients with glaucoma's ocular surface status should be evaluated regularly to ensure the timely detection and treatment of pathologic signs on the ocular surface.

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Changes the Ocular Surface after Corneal Refractive Surgery. Review

Ophthalmology in Russia ◽

10.18008/1816-5095-2020-3-344-350 ◽

2020 ◽

Vol 17 (3) ◽

pp. 344-350

Author(s):

S. V. Trufanov ◽

E. V. Sukhanova ◽

A. A. Tyurina

Keyword(s):

Dry Eye ◽

Ocular Surface ◽

Refractive Surgery ◽

High Efficiency ◽

High Specificity ◽

Functional Results ◽

Dry Eye Syndrome ◽

Specificity And Sensitivity ◽

Surgery Research ◽

Corneal Refractive Surgery

Modern corneal refractive surgery provides high efficiency, safety, predictability and stability of the different ametropia kinds correction’s clinically-functional results. However, in overwhelming percentage of cases, having spent some time after surgery patients complain about discomfort, eyes dryness, burning, feel gritty, redness, blurred and vision instability. Complaints mentioned above are caused by the appearance of transitory dry eye syndrome. Main etiology and pathogenesis factors of this disease are presented in this review. The results of dry eye syndrome classical diagnosis methods have been analyzed, as well as modern techniques, characterized by high specificity and sensitivity, which allow to increase the dry eye’s diagnostics accuracy. The study of the dry syndrome after corneal refractive surgery is devoted to a huge number of works of domestic and foreign authors. However, at present time there is no unique algorithm for assessing the damage of the ocular surface before and after corneal refractive surgery, which would include a set of high-precision and specific techniques for quickly and reliably evaluate the severity of dry eye syndrome, allowing to develop preventive measures and pathogenetically oriented treatment and, thereby, accelerate rehabilitation of patients after surgery. Research continuation is needed in this direction.

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