Some epidemiological characteristics of malignant fibrous histiocytoma in the Province of Vojvodina

BACKGROUND: Malignant fibrous histiocytoma is most common soft tissue sarcoma occurring in late adult life, most in the extremities and in the retroperitoneum, usually developing in deep fascia or skeletal muscle. Because of the aggressive nature of the tumor early and complete surgical removal is indicated. The overall survival rate of patients with malignant fibrous histiocytoma ranges from 36% to 58% at 5 years. Malignant fibrous histiocytoma in Vojvodina is still rare malignancy either in incidence or in mortality in both sexes. The population of Vojvodina is about 2 100 000. METHODS: We used a descriptive epidemiological method to analyze incidence and mortality from malignant fibrous histiocytoma in Vojvodina. This study is based on the Cancer Registry data for the ten-year period from 1993 to 2002. RESULTS: During the observed period 37 cases of malignant fibrous histiocytoma were reported (19 men and 18 women). The average age of patients was 50 years. The body site distribution differed between sexes and malignant fibrous histiocytoma was more common on the trunk (retroperitoneum) in men and on the lower limbs in women. The average annual incidence rate for the observed period was 1.82 per 1 000 000 for both sexes. The incidence rate changed irregularly over the observed period with the peak of 9 cases (4.55 per 1 000 000) in 2001. The overall linear trends of incidence and of mortality showed a slight increasing tendency in both sexes, but not significantly. Concerning mortality, the similar patterns were noticed. The mortality rate was 0.83 per 1 000 000. CONCLUSION: According to epidemiological data we obtained it can be concluded that Province of Vojvodina is not a region with an important risk for malignant fibrous histiocytoma; however, the increase of incidence appearing in both men and women should be taken into account very seriously in future.

Download Full-text

DEDIFFERENTIATED LIPOSARCOMA PAYUDARA (LAPORAN KASUS)

JURNAL BIOMEDIK (JBM) ◽

10.35790/jbm.3.3.2011.877 ◽

2013 ◽

Vol 3 (3) ◽

Author(s):

Poppy M. Lintong ◽

Eddy H. Tambajong

Keyword(s):

Lymph Nodes ◽

Alcian Blue ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Histopathological Examination ◽

Breast Tumors ◽

The Body ◽

Dedifferentiated Liposarcoma ◽

Cystosarcoma Phyllodes ◽

Tumor Tissues

Abstrak: Liposarkoma primer pada payudara termasuk salah satu tumor payudara yang sa-ngat jarang, insidennya kurang dari 1% dari semua tumor ganas payudara. Umumnya liposarkoma pada payudara jarang atau tidak menyebar ke kelenjar getah bening aksila. Gambaran histologik liposarkoma pada payudara sama dengan liposarkoma di ekstrimitas atau tubuh. Suatu liposarkoma yang sejati pada payudara ditegakkan bilamana gambaran cystosarcoma phyllodes tidak ditemukan dalam potongan-potongan jaringan tumor. Satu kasus dilaporkan pada seorang wanita usia 49 tahun dengan tumor payudara besar. Gambaran Dedifferentiated Liposarcoma secara makroskopik menunjukkan massa multinoduler besar, warnanya bervariasi dari kuning, kuning kecoklatan bercampur coklat keabu-abuan. Mikroskopik terdiri dari 2 komponen yaitu lipogenik, menunjukkan gambaran liposarkoma diferensiasi baik; dan nonlipogenik (dedifferentiated). Daerah dedifferentiated menunjukkan gambaran fibrosarkoma, malignant fibrous histiocytoma, dan liposarkoma miksoid. Daerah yang menyerupai malignant fibrous histiocytoma menunjukkan gambaran sitologik pleo-morfisme, arsitektur storiform, dan sel-sel datia. Fokus-fokus liposarkoma miksoid telah dibuat pulasan dengan Alcian blue hasilnya positip. Kata kunci: dedifferentiated liposarcoma, payudara. Abstract: Primary liposarcoma of the breast belongs to very rarely found breast tumors, hav-ing an incidence of less than 1% of all malignant breast tumors. In general, this liposarcoma rarely or does not spread to axillar lymph nodes. Histopathologically, liposarcoma of the breast is similar to liposarcoma in extremities and other parts of the body. A true liposarcoma of the breast is diagnosed if there is no cystosarcoma phyllodes in the tumor tissues. We re-ported a 49-year-old female with a huge breast tumor (21x18x15cm), associated with four lymph nodes in the ipsilateral axilla. Histopathological examination of the tumor tissues showed a dedifferentiated liposarcoma, and of the four lymph nodes, as well as reactive hyperplasia with no metastase. Macroscopically, this dedifferentiated liposarcoma, appeared as large multinodular masses ranging in color from yellow to yellow-tan admixed with firm tan-gray areas. Microscopically, it consisted of two components: lipogenic, a well differen-tiated liposarcoma; and nonlipogenic, dedifferentiated one. These dedifferentiated areas showed a fibrosarcoma, malignant fibrous histiocytoma, and mixoid liposarcoma. Areas of malignant fibrous histiocytoma looked cytologic pleomorphisme, storiform architecture, and multinucleate cells. Foci of mixoid liposarcoma were stained with Alcian blue, and showed positive results. Key words: dedifferentiated liposarcoma, breast.

Download Full-text

Case for diagnosis

Anais Brasileiros de Dermatologia ◽

10.1590/s0365-05962012000400026 ◽

2012 ◽

Vol 87 (4) ◽

pp. 647-648

Author(s):

Mariana Hammerschmidt ◽

Luciana Menezes de Azevedo ◽

Anelisa Ruaro ◽

Betina Werner ◽

Alexandre do Nascimento ◽

...

Keyword(s):

Elderly People ◽

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma ◽

Skin Tumors ◽

The Body ◽

Neoplastic Cells ◽

Atypical Fibroxanthoma ◽

Cutaneous Tumor

Atypical fibroxanthoma is a rare cutaneous tumor found mainly in elderly people on sun-exposed areas of the body. Histologically, atypical fibroxanthoma is considered a malignant fibrous histiocytoma with bizarre neoplastic cells, marked pleomorphism, hyperchromatic nuclei and abundant mitoses. It must be differentiated from other skin tumors, usually by immunohistochemistry, since its diagnosis is made by exclusion.

Download Full-text

Anatomical Findings at Acupuncture Loci

The American Journal of Chinese Medicine ◽

10.1142/s0192415x8000013x ◽

1980 ◽

Vol 08 (01n02) ◽

pp. 170-180 ◽

Cited By ~ 14

Author(s):

J. P. Plummer

Keyword(s):

Subcutaneous Tissue ◽

The Body ◽

Neurovascular Bundle ◽

Lower Limbs ◽

Acupuncture Points ◽

Deep Fascia ◽

Autonomic Nerves ◽

Supporting Evidence ◽

Perforating Veins ◽

Perforating Vein

A number of investigators have noted the presence of neural structures beneath acupuncture loci either in superficial or deep structures only, or else in both superficial and deep structures. The fact the acupuncture loci correspond to motor points and trigger points is also now well recognized. However, the presence of venous structures beneath acupuncture loci is not so well documented. The presence of a "communicating" or "perforating" vein beneath many points, and the apparent correspondence of known common sites of such veins in the lower limbs with acupuncture points in reported. It is proposed that the failure of acupuncture analgesia and acupuncture therapy in a proportion of cases may be due to the irregularity of the sites of the perforating veins, although their sites may be somewhat more fixed than sometimes thought. The absence of acupuncture points in areas where there is also known absence of perforating veins, e.g. bony areas such as the medial subcutaneous surface of the tibia, is also put forward as "negative" supporting evidence for the relationship between acupuncture loci and perforating veins. Moreover the more recent "discovery" of so many new or "strange" acupuncture loci may be due to the irregularity of the sites of these veins in many people. It is proposed that the nature of acupuncture loci is actually two holes, one in the dermis due to a neurovascular bundle or nerve piercing it, and one (or even more) directly beneath it (although separated by subcutaneous tissue) in the deep fascia due to a perforating vein, neurovascular bundle or nerve piercing it. The correspondence of these holes may allow relatively greater passage of biological electrical current from deeper tissues to the surface of the body, and autonomic nerves at these points may thus be involved in monitoring this current for purposes of homeostasis.

Download Full-text

Stomach Cancer

10.1093/oso/9780190238667.003.0031 ◽

2017 ◽

Cited By ~ 1

Author(s):

Catherine de Martel ◽

Julie Parsonnet

Keyword(s):

Stomach Cancer ◽

Population Aging ◽

Molecular Classification ◽

Absolute Number ◽

The Body ◽

Incident Cancer ◽

Incidence And Mortality ◽

Signet Ring ◽

H Pylori ◽

Epidemiological Characteristics

Stomach cancer is the fifth most common incident cancer worldwide and the third leading cause of cancer death. Almost half of the world’s cases occur in Asia, with 42% in China alone. Although the incidence and mortality rates from stomach cancer are decreasing, the global disease burden remains high. Moreover, the absolute number of cases continues to rise because of population aging. Adenocarcinomas comprise over 90% of gastric malignancies. The adenocarcinomas are further classified according to anatomic location (cardia vs. non-cardia), histology (e.g., intestinal or diffuse, signet ring or non-signet ring) and most recently by molecular classification. Adenocarcinomas in the body and antrum of the stomach are usually caused by chronic infection with Helicobacter pylori (H. pylori); the incidence of these tumors is decreasing worldwide. Cardia tumors have epidemiological characteristics more similar to those of esophageal adenocarcinoma; the incidence of these tumors is increasing, particularly in high-income Western countries.

Download Full-text

Primary Malignant Fibrous Histiocytoma: A Rare Case

Case Reports in Medicine ◽

10.1155/2011/134801 ◽

2011 ◽

Vol 2011 ◽

pp. 1-3 ◽

Cited By ~ 2

Author(s):

Anastasios Katsourakis ◽

George Noussios ◽

Iosif Hadjis ◽

Neofitos Evangelou ◽

Efthimios Chatzitheoklitos

Keyword(s):

Small Intestine ◽

Adjuvant Chemotherapy ◽

Malignant Fibrous Histiocytoma ◽

Rare Case ◽

Fibrous Histiocytoma ◽

Rare Condition ◽

Surgical Removal ◽

High Grade ◽

Biological Behaviour ◽

Pleomorphic Sarcoma

Malignant fibrous histiocytoma (MFH) of the small intestine is an extremely rare condition. It occurs most commonly in the extremities and the trunk. We report a case of a 67-year-old woman who admitted with fever, myalgia, and altered status. After thorough investigation, a tumor of the jejunum was found. The patient underwent complete surgical removal of the tumor. A diagnosis of MFN (undifferentiated high-grade pleomorphic sarcoma) was made. The patient received adjuvant chemotherapy with Gemcitabine. Two years after the operation, the patient died due to recurrence of the disease. MFH of the small intestine is an extremely rare neoplasm with an aggressive biological behaviour. In this paper, pathogenesis, natural history, and treatment are reviewed.

Download Full-text

Primary intracranial malignant fibrous histiocytoma

European Journal of Radiology ◽

10.1016/s0720-048x(03)00060-3 ◽

2003 ◽

Author(s):

P Kosucu

Keyword(s):

Malignant Fibrous Histiocytoma ◽

Fibrous Histiocytoma

Download Full-text

Aspergillus Spondylodiscitis After Spinal Stenosis Surgery: A Case Report

Iranian Journal of Neurosurgery ◽

10.32598/irjns.5.3.9 ◽

2020 ◽

Vol 5 (3 And 4) ◽

pp. 155-160

Author(s):

Mohsen Aghapoor ◽

◽

Babak Alijani Alijani ◽

Mahsa Pakseresht-Mogharab ◽

◽

...

Keyword(s):

Antifungal Drugs ◽

The Body ◽

Lower Limbs ◽

Lumbar Pain ◽

Case Presentation ◽

Delay In Diagnosis ◽

Death Case ◽

Therapeutic Results ◽

History Of ◽

Probable Diagnosis

Background and Importance: Spondylodiscitis is an inflammatory disease of the body of one or more vertebrae and intervertebral disc. The fungal etiology of this disease is rare, particularly in patients without immunodeficiency. Delay in diagnosis and treatment of this disease can lead to complications and even death. Case Presentation: A 63-year-old diabetic female patient, who had a history of spinal surgery and complaining radicular lumbar pain in both lower limbs with a probable diagnosis of spondylodiscitis, underwent partial L2 and complete L3 and L4 corpectomy and fusion. As a result of pathology from tissue biopsy specimen, Aspergillus fungi were observed. There was no evidence of immunodeficiency in the patient. The patient was treated with Itraconazole 100 mg twice a day for two months. Pain, neurological symptom, and laboratory tests improved. Conclusion: The debridement surgery coupled with antifungal drugs can lead to the best therapeutic results.

Download Full-text