scholarly journals Hypothermia as the cause of death in forensic pathology: Autopsy study

2010 ◽  
Vol 138 (7-8) ◽  
pp. 467-472 ◽  
Author(s):  
Slobodan Nikolic ◽  
Magdalena Zivkovic ◽  
Vladimir Zivkovic ◽  
Fehim Jukovic

Introduction. The body cooling process goes through few clinical phases. These are followed by some morphological thanatological changes such as frost erythema and Wischnewsky's spots, which are used in diagnosis of death due to hypothermia. In such cases there is no any specific autopsy finding. Objective. To establish the frequency of hypothermia as the cause of death for a ten-year-period, and to analyze the sample according to gender and age, risk factors and autopsy findings of subjects. Methods. A retrospective autopsy study was performed for a ten-year-period (total of 12,765 forensic autopsies). The relevant data were collected from autopsy records, police reports and heteroanamnestic interviews. The sample was analyzed according to gender, age, scene of death, blood alcohol concentration, risk factors, and autopsy findings of all observed subjects. Results. The sample included 67 subjects, 42 males and 25 females (?2=4.31; p<0.05), of average age 63.9?14.7 years (min=27, max=92; med=65, mod=55). Nineteen of subjects were found at in-door places. In 13 subjects blood alcohol concentration ranged from 0.50 to 3.32 promille (average 1.81?0.93). The younger the observed subject was, the higher the blood alcohol concentration (?=-0.251; p=0.04). One third of the observed subjects were chronic alcohol abusers. Thirteen persons had psychiatric diseases. In 43 observed subjects the concomitant appearance of frost erythema and Wischniewsky's spots were established (?2=49.59; df=3; p<0.001). Conclusion. In the analyzed ten-year period hypothermia was not often the cause of death; it was disclosed only in 0.5% of the total number of the studied autopsies. The most of the deceased were older males with cardiovascular problems found in unprotected open-air places. The most frequent thanatological findings in the analyzed subjects were frost erythema and Wischnewsky's spots.

2010 ◽  
Vol 138 (9-10) ◽  
pp. 590-594 ◽  
Author(s):  
Vladimir Zivkovic ◽  
Borislav Miletic ◽  
Slobodan Nikolic ◽  
Fehim Jukovic

Introduction. Sudden natural death occurs unexpectedly in apparently healthy subjects, or in persons during an apparent benign phase in the course of disease. The most common cause is sudden cardiac death, which is sometimes the first and last manifestation of coronary heart disease. Alcohol directly influences excitation of myocytes, and therefore provokes arrhythmias and possibly, sudden cardiac death. Objective. To establish the frequency of sudden cardiac death in cases of acute alcohol intoxication, to determine blood alcohol concentration at the moment of death, and to determine frequency and level of ethanol intoxication in chronic alcohol abusers, as well as causes of sudden death in those cases. Method. Retrospective autopsy study was performed for a three-year-period. We analyzed cases of sudden natural death, in relation to age and gender, cause of death, and blood alcohol concentration (at least 0.5 g/L). We considered the person to be a chronic alcoholic abuser if gross examination of organs during autopsy showed changes typical for excessive and habitual alcohol consumption. Results. Our sample consisted of 997 cases: 720 men and 277 women, average age 62.0?15.2 years (min=11; max=98). Total of 753 of them died of sudden cardiac death: much more men (?2=167.364; p=0.000), significantly younger than women (t=6.203; p=0.000). We determined acute alcohol intoxication in 73 persons - average blood alcohol concentration 1.85?1.01 g/L (min=0.55; max=3.85), and 61 of them died of cardiovascular diseases (?2=236.781; df=5; p=0.000). Conclusion. In our observed sample, not many persons were under acute alcohol intoxication (around 7%). Most commonly, they were chronic alcohol abusers who died due to exacerbation of chronic heart disease, mildly or moderately intoxicated - the younger, the drunker.


2017 ◽  
Vol 62 (6) ◽  
pp. 1506-1511 ◽  
Author(s):  
Danica Cvetković ◽  
Vladimir Živković ◽  
Vera Lukić ◽  
Slobodan Nikolić

2021 ◽  
Author(s):  
Antonio Oliver Gelabert

A theoretical model based on mass conservation is proposed to predict blood alcohol concentration (BAC) over time. The proposed model takes as input the body parameters, the data timing for each drink, as well as his alcoholic strength and ingested amount. Three test cases with variations are presented and discussed. The results given are obtained by solving numerically the equation proposed. The solution predicts a well located alcohol peak and a reasonable time of alcohol body cleaning. This model represents a first order approach to a complex problem. Similar scenarios, like, for instance, drug concentrations can be modelled by using the same concept. The proposed model has been implemented on easy-to-use program COGORZA, which source code is available online at https://github.com/tonibois/Cogorza.


2018 ◽  
Author(s):  
James M Clay ◽  
Matthew O Parker

Rationale: Hazardous drinking presents a global health risk and if chronic, can escalate into an alcohol use disorder. The causal mechanisms for the transition from controlled alcohol use to uncontrolled misuse and dependence are complex, and it is not presently possible to accurately predict those most at-risk of misusing alcohol, or of developing AUD. Objectives: We investigated the feasibility of using ecological momentary assessments, specifically related to daily stress and alcohol use, to study risk factors for hazardous drinking. We tested the hypothesis that in a sample of healthy drinkers, risk-taking would modulate the impact of daily self-reported stress on alcohol use.Methods: We characterised impulsivity/risk-taking in 23 participants (12 female; mean age = 24.59 [SD = 5.34]) using a battery of questionnaires and computer tasks. We then collected daily behavioural and physiological data related to self-reported stress levels and blood alcohol concentration consumption for 30 days.Results: Attrition and missing data rates were low, with an overall response rate of 92.6% We found support for our hypothesis, with higher risk-taking and impulsive participants drinking more following daily stressors. However, the picture was not clear, with participants drinking greater volumes of alcohol at weekends, and the interactions of stress x personality trait often differing on weekdays.Conclusions: This feasibility study demonstrated the potential for was the first to demonstrate that using ecological momentary assessments, such as, digital biomarkers to assess risk factors for alcohol misuse is a viable option for investigating the effects of neurocognitive endophenotypes and stress on alcohol misuse on a longitudinal basis.


2018 ◽  
Vol 69 (9) ◽  
pp. 2407-2410
Author(s):  
Dan Perju Dumbrava ◽  
Carmen Corina Radu ◽  
Sofia David ◽  
Tatiana Iov ◽  
Catalin Jan Iov ◽  
...  

Considering the growing number of requests from the criminal investigations authorities addressed to the institutions of legal medicine, testing of blood alcohol concentration both in the living person and in the corpse, we believe that a presentation of the two methods which are used in our country, is a topic of interest at present. The purpose of this article is to provide the reader with the technical details on how blodd alcohol concentration is realised by means of the gas chromatographic method and the classical one, (Cordebard modified by D. Banciu and I. Droc) respectively. Another purpose of this article is to also show, in a comparative way, the elements that make the gas chromatographic method superior to the former one.


Author(s):  
R. Wade Allen ◽  
Zareh Parseghian ◽  
Anthony C. Stein

There is a large body of research that documents the impairing effect of alcohol on driving behavior and performance. Some of the most significant alcohol influence seems to occur in divided attention situations when the driver must simultaneously attend to several aspects of the driving task. This paper describes a driving simulator study of the effect of a low alcohol dose, .055 BAC (blood alcohol concentration %/wt), on divided attention performance. The simulation was mechanized on a PC and presented visual and auditory feedback in a truck cab surround. Subjects were required to control speed and steering on a rural two lane road while attending to a peripheral secondary task. The subject population was composed of 33 heavy equipment operators who were tested during both placebo and drinking sessions. Multivariate Analysis of Variance showed a significant and practical alcohol effect on a range of variables in the divided attention driving task.


1994 ◽  
Vol 34 (3) ◽  
pp. 265-270 ◽  
Author(s):  
A W Jones

This article describes a drink-driving scenario where a woman was apprehended for driving under the influence (DUI) with a blood alcohol concentration (BAC) of 256mg/dl1 The correctness of this result was vigorously challenged by a medical expert witness for the defence, who was actually a specialist in alcohol diseases. Despite reanalysis to confirm the BAC as well as a DNA profile to prove the identity of the blood specimen, the woman was acquitted of the charge of drunk driving by the lower court. However, she was subsequently found guilty in the High Court of Appeals with a unanimous decision and sentenced to four weeks imprisonment. This case report illustrates some of the problems surrounding the use of expert medical evidence by the defence to challenge the validity of the prosecution evidence based solely on a suspect's BAC. In situations such as these, an expert witness should be called by the prosecution to clarify and, if necessary, rebut medical and/or scientific opinions that might mislead the court and influence the outcome of the trial.


2013 ◽  
Vol 58 (5) ◽  
pp. 1238-1250 ◽  
Author(s):  
Teri L. Martin ◽  
Patricia A. M. Solbeck ◽  
Daryl J. Mayers ◽  
Robert M. Langille ◽  
Yvona Buczek ◽  
...  

2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Karen Hughes ◽  
Zara Quigg ◽  
Mark A Bellis ◽  
Ninette van Hasselt ◽  
Amador Calafat ◽  
...  

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