scholarly journals Primary leptomeningeal melanocytosis: A case report with an autopsy diagnosis

2012 ◽  
Vol 69 (7) ◽  
pp. 631-634 ◽  
Author(s):  
Nikola Zivkovic ◽  
Dragan Mihailovic ◽  
Zaklina Mijovic ◽  
Maja Jovicic-Milentijevic

Introduction. Primary melanocytosis of the leptomeninges is a rare tumor, most likely originating from the melanocytes in the leptomeninges. The average survival is only about 5 months. Case report. A 61- years-old woman presented with headache, amaurosis and hallucinations lasted for two months, and she had been treated at the Clinic for Psychiatry and Clinic for Infectious Diseases. The cerebrospinal fluid analysis showed a lower level of glucose and a higher level of proteins. Small shaded areas of basal leptomeninges and hydrocephalus were found by computed tomography and magnetic resonance imaging. The autopsy showed a dark brown mass on basal leptomeninges with blurred boundaries. No pigmented skin lesions were found. Histopathological analysis revealed a primary leptomeningeal melanocytosis. Conclusion. Primary leptomeningeal melanocytosis is a rare tumor, difficult to diagnose. This case is being presented for its specificity, since this diagnosis is not frequently seen in practice.

2012 ◽  
Vol 57 (No. 5) ◽  
pp. 270-273
Author(s):  
Z. Adamiak ◽  
A. Pomianowski ◽  
I. Otrocka-Domagala ◽  
M. Jaskolska

A canine patient with osteosarcoma of the sacrum was subjected to low-field magnetic resonance imaging with the following sequences: FSE, SE, 3D HYCE, X BONE, Fast STIR, GE STIR and Gradient Echo. Due to the size and location of the tumour, surgery was not performed, and the patient was euthanized. A histopathological analysis of the tumour revealed telangiectatic osteosarcoma.    


2014 ◽  
Vol 8 (08) ◽  
pp. 1076-1078 ◽  
Author(s):  
Rupali Malik ◽  
Arun Gogna ◽  
Jhasketan Meher ◽  
Kumud Kumar Singh ◽  
Susheel Kumar Sharma

Dengue encephalopathy or dengue hemorrhagic fever (DHF) with neurological involvement was once considered to be one of the rarer presentations of this infectious agent. In recent years, many such clinical cases have been reported, though they still remain isolated. We hereby report a case of confirmed dengue fever with features of encephalopathy with previously unreported cranial magnetic resonance imaging findings suggestive of extensive involvement of the bilateral cerebellar region, brainstem, and thalami along with peculiar rim enhancement but normal cerebrospinal fluid analysis.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Murat Tolga Gulpinar ◽  
Asif Yildirim ◽  
Berrin Gucluer ◽  
Ramazan Gokhan Atis ◽  
Cengiz Canakci ◽  
...  

Primary adrenal leiomyosarcoma is extremely rare tumor. We report a case with adrenal leiomyosarcoma. Our case was a 48-year-old man who presented with lower urinary tract symptoms. Ultrasonography and magnetic resonance imaging revealed approximately 9 cm solid mass originating from right adrenal gland. He underwent right adrenalectomy. Pathology of the specimen showed histologic and immunohistochemical features of adrenal leiomyosarcoma.


2008 ◽  
Vol 14 (7) ◽  
pp. 1003-1006 ◽  
Author(s):  
P Invernizzi ◽  
MA Bonometti ◽  
E Turri ◽  
MD Benedetti ◽  
A Salviati

We present the case of a 36-year-old woman affected with Fabry disease (FD), with neuroradiologic and laboratory tests suggestive of a coexistent inflammatory demyelinating disease. Since the age of 23, she presented recurrent neurologic deficits, such as right limb paresthesias, diplopia, and right leg weakness. Magnetic resonance imaging revealed multiple demyelinating lesions in periventricular areas, corpus callosum, and spinal cord. Cerebrospinal fluid analysis showed the presence of oligoclonal bands, while visual-evoked potentials were delayed with preserved morphology. FD is usually considered as a differential diagnosis of multiple sclerosis, but we think that the best explanation of all pathological features in this case is the coexistence of the two diseases.


1994 ◽  
Vol 24 (2) ◽  
pp. 525-529 ◽  
Author(s):  
M. H. Hotopf ◽  
S. Pollock ◽  
W. A. Lishman

SynopsisTwo male patients who presented with unusual pictures of dementia in the absence of other obvious symptoms or signs are reported. Investigations demonstrated changes highly suggestive of multiple sclerosis (MS) on magnetic resonance imaging, cerebrospinal fluid analysis and electrophysiological tests. We suggest this represents a rare presentation of multiple sclerosis.


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