Motor Activity in Vitro of Rat Small Intestine Following Whole-Body X-Irradiation

1970 ◽  
Vol 42 (3) ◽  
pp. 565 ◽  
Author(s):  
Martin F. Kagnoff
Keyword(s):  
Small Intestine ◽  
Motor Activity ◽  
Whole Body ◽  
Rat Small Intestine ◽  
X Irradiation

Whole-Body Irradiation and Active Transport in the Rat Small Intestine in Vitro

1966 ◽  
Vol 29 (4) ◽  
pp. 597 ◽  
Author(s):  
A. D. Perris
Keyword(s):  
Small Intestine ◽  
Active Transport ◽  
Whole Body ◽  
Rat Small Intestine

scholarly journals Effect of Whole-body X-irradition on Glucose Oxidation by Rat Small Intestine Mucosa in Vitro

1959 ◽  
Vol 234 (7) ◽  
pp. 1634-1640
Author(s):  
Robert E. Kay ◽  
Cecil Entenman
Keyword(s):  
Small Intestine ◽  
Glucose Oxidation ◽  
Whole Body ◽  
Rat Small Intestine ◽  
Intestine Mucosa

scholarly journals Absorption of lactulose from mammalian gastrointestinal tract

1979 ◽  
Vol 41 (1) ◽  
pp. 47-51 ◽  
Author(s):  
D. F. Evered ◽  
F. Sadoogh-Abasian
Keyword(s):  
Small Intestine ◽  
Calcium Ions ◽  
Clinical Evidence ◽  
Buccal Cavity ◽  
Rat Small Intestine ◽  
Sodium Ions ◽  
Mode Of Transport ◽  
Poor Absorption

1. The disaccharide lactulose (galactosyl-β-1,4-fructose) was poorly absorbed from rat small intestine in vitro and human mouth in vivo.2. These results confirm indirect clinical evidence of poor absorption from the intestine.3. The presence of calcium ions, or absence of sodium ions, had no effect on lactulose absorption from the buccal cavity.4. The presence of ouabain, or absence of Na+, did not decrease the absorption of lactulose from small intestine.5. It is thought that the mode of transport, in both instances, is by passive diffusion with the concentration gradient.

Pyruvate transport across mucosa of rat small intestine in vitro

1986 ◽  
Vol 14 (2) ◽  
pp. 299-300
Author(s):  
JOHN E. LAWRENCE ◽  
DEREK F. EVERED
Keyword(s):  
Small Intestine ◽  
Rat Small Intestine

scholarly journals Biochemical Studies on Oral Toxicity of Ricin. Part III. Interaction of Toxic Lection Ricin with Epithelial Cells of Rat Small Intestine in Vitro.

1992 ◽  
Vol 40 (2) ◽  
pp. 441-445 ◽  
Author(s):  
Masatsune ISHIGURO ◽  
Hidemi NAKASHIMA ◽  
Shuichi TANABE ◽  
Ryozo SAKAKIBARA
Keyword(s):  
Small Intestine ◽  
Epithelial Cells ◽  
Rat Small Intestine ◽  
Oral Toxicity ◽  
Biochemical Studies

Demonstration and modification of intervillous pH profiles in rat small intestine in vitro

1989 ◽  
Vol 257 (4) ◽  
pp. G489-G495 ◽  
Author(s):  
H. Daniel ◽  
C. Fett ◽  
A. Kratz
Keyword(s):  
Small Intestine ◽  
Low Ph ◽  
Rat Small Intestine ◽  
Ph Profile ◽  
Subsequent Increase ◽  
Alkaline Secretion ◽  
Alkaline Fluid ◽  
Ph Profiles

The intervillous pH profiles along the crypt villus axis in different regions of the rat small intestine were measured in vitro by using pH-sensitive liquid ion-exchanger microelectrodes. A characteristic pH profile was observed in the duodenum and jejunum. A region of low pH was detected in the upper parts of the villi (pH 6.65 +/- 0.06 to 6.85 +/- 0.07), whereas pH at the villus base was always higher. In the ileum no gradient was observed (pH 7.26 +/- 0.05 to 7.31 +/- 0.05). Preincubation of the tissue in situ with 10 mM theophylline for 1 h caused an increase in the villus base pH in the jejunum (pH 7.24 +/- 0.04) and ileum (7.44 +/- 0.04) followed by a subsequent increase of the pH in the upper part of the villi. These results indicate that the low pH in the upper intervillous space may be related to H+ secretion occurring from the mature enterocytes, whereas the crypt cells may secrete a rather neutral or slightly alkaline fluid. Alkaline secretion from the crypts may be increased by theophylline, which changes the levels of cyclic nucleotides in the mucosa.

Uptake and compartmental distribution of fatty acid by rat small intestine in vivo

1975 ◽  
Vol 228 (5) ◽  
pp. 1409-1414
Author(s):  
S Mishkin ◽  
M Yalovsky ◽  
JI Kessler
Keyword(s):  
Fatty Acids ◽  
Small Intestine ◽  
Fatty Acid ◽  
Entire Length ◽  
Rat Small Intestine ◽  
Pass Through

The uptake and esterification of micellar [3-H]oleate and [14-C] palmitate were uniform along the entire length of the small intestine in vivo. Fatty acids (FA) radioactivity taken up by the small intestine could be described in terms of four functionally distinct compartments analogous to those described in vitro. The KRP-extractable compartment (KEC) and albumin-extractable compartment (AEC) contained reversibly adherent unesterified FA radioactivity, while the tissue free and esterified FA compartments contained irreversibly bound radioactivity. Wheras 27% and 63% of FA uptake were reversibly bound in the KEC and AEC by the most proximal and most distal regions of the small intestine in vitro (15), less than 10% was contained in these compartments in vivo, independent of location. Linear inverse relationships were found betweeen tissue FA esterification and proportion of FA radioactivity present in the KEC,AEC, and the tissue free FA compartment in vivo. These observations allow for the possibility that FA molecules pass through these compartments prior to esterification.

scholarly journals Distribution of glucose-6-phosphatase activity in mice studied by in vitro whole-body autoradiography.

1983 ◽  
Vol 31 (12) ◽  
pp. 1426-1429 ◽  
Author(s):  
M Watanabe ◽  
H Goto ◽  
M Matsushima ◽  
R Shimono ◽  
T Kihara
Keyword(s):  
Small Intestine ◽  
Phosphatase Activity ◽  
Enzyme Activities ◽  
Whole Body ◽  
Skeletal System ◽  
Whole Body Autoradiography ◽  
G6pase Activity ◽  
High Radioactivity

The distribution of the glucose-6-phosphatase (G6Pase) activities was demonstrated by in vitro whole-body autoradiography. Relatively high activities were observed in the liver, kidney, and small intestine of mice. However, these organs did not exhibit uniform activity throughout. The activity of the liver was found heterogeneous, but that of the duodenum and jejunum were higher than for those of other parts of the intestine. G6Pase activity was higher in the cortex of the kidney than in the medulla. In addition to these observations, it was also found that the skeletal system had high radioactivity. These results were similar to those from biochemical experiments. This method of in vitro whole-body autoradiography would seem to be of value in studying macroscopic distributions of other enzyme activities in organs as well as in whole-body.

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