Nature and Clinical Impact of Physiologic Changes Associated with Aging

Mapping Intimacies ◽

10.2310/vasc.2223 ◽

2017 ◽

Author(s):

Omeed Moaven ◽

Carlo M Contreras

Keyword(s):

Perioperative Management ◽

Clinical Impact ◽

Surgical Patients ◽

Key Words Aging ◽

Precipitating Factors ◽

Expert Opinions ◽

Age Related ◽

Clinical Consequences ◽

Consensus Expert ◽

Age Related Changes

This review highlights important age-related changes at the physiologic level and their clinical consequences. Latest societal guidelines and consensus expert opinions on pre- and perioperative management of elderly surgical patients are discussed. Age-related postoperative complications, including precipitating factors and appropriate management, are summarized. The latest advancements in the management of important surgical problems in geriatric populations are outlined. This review contains 4 figures, 8 tables, and 103 references. Key words: aging, elderly patient, immunosenescence

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Nature and Clinical Impact of Physiologic Changes Associated with Aging

DeckerMed Surgery ◽

10.2310/surg.2223 ◽

2017 ◽

Author(s):

Omeed Moaven ◽

Carlo M Contreras

Keyword(s):

Perioperative Management ◽

Clinical Impact ◽

Surgical Patients ◽

Key Words Aging ◽

Precipitating Factors ◽

Expert Opinions ◽

Age Related ◽

Clinical Consequences ◽

Consensus Expert ◽

Age Related Changes

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Drug interactions involving psychotropic drugs

Mental Disorders in Primary Care ◽

10.1093/med/9780198746638.003.0021 ◽

2017 ◽

Author(s):

Subramoniam Madhusoodanan ◽

Marina Tsoy-Podosenin ◽

Leah R. Steinberg ◽

Nitin Tandan

Keyword(s):

Drug Interactions ◽

Patient Participation ◽

Psychotropic Drugs ◽

The Elderly ◽

Herbal Drugs ◽

Over The Counter ◽

Disease States ◽

Age Related ◽

Clinical Consequences ◽

Age Related Changes

This chapter covers the various drug interactions of psychotropic agents with other drugs, over the counter (OTC) medications, food substances, herbals, alcohol, and smoking. The basic mechanisms of pharmacokinetics, pharmacodynamics, and other interactions are discussed. The disease states and age-related changes underlying the drug interactions in the elderly are briefly addressed. Drug interactions discussed have been classified as severe, moderate, or mild, according to the severity of their anticipated clinical consequences. Serious complications including death may occur in severe interactions involving cardiovascular drugs. A thorough understanding of the basis of drug interactions, and patient participation in the treatment are vital. It is also particularly important to compile a list of medications, including OTC and herbal drugs, currently taken by the patient.

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