A Case of Subcorneal Pustular Dermatosis in a Patient with Essential Thrombocythemia Accompanied by a High Plasma Level of TNF-alpha

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A 16-year-old woman deliberately took a large, toxic overdose of carbamazepine and recovered despite a high plasma level. During the acute phase the EEG was dominated by occipital delta activity suggestive of a brainstem disorder. Following 24-h treatment with activated charcoal the plasma carbamazepine was cleared and the EEG returned to normal.


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