Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

Natalie Lefort; Brian Glancy; Benjamin Bowen; Wayne T. Willis; Zachary Bailowitz; Elena A. De Filippis; Colleen Brophy; Christian Meyer; Kurt Højlund; Zhengping Yi; Lawrence J. Mandarino

doi:10.2337/db10-0174

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

Diabetes ◽

10.2337/db10-0174 ◽

2010 ◽

Vol 59 (10) ◽

pp. 2444-2452 ◽

Cited By ~ 103

Author(s):

Natalie Lefort ◽

Brian Glancy ◽

Benjamin Bowen ◽

Wayne T. Willis ◽

Zachary Bailowitz ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Skeletal Muscle ◽

Mitochondrial Respiration ◽

Complex I ◽

Reactive Oxygen Species Production ◽

Human Skeletal Muscle ◽

Carnitine Palmitoyltransferase ◽

Oxygen Species ◽

Insulin Resistant ◽

Species Production

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Effects of acute hyperinsulinemia on skeletal muscle mitochondrial function, reactive oxygen species production, and metabolism in premenopausal women

Metabolism ◽

10.1016/j.metabol.2017.08.004 ◽

2017 ◽

Vol 77 ◽

pp. 1-12 ◽

Cited By ~ 4

Author(s):

Jonathan L. Warren ◽

Sule Bulur ◽

Fernando Ovalle ◽

Samuel T. Windham ◽

Barbara A. Gower ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Skeletal Muscle ◽

Mitochondrial Function ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Premenopausal Women ◽

Oxygen Species ◽

Species Production

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Reactive oxygen species production in cardiac mitochondria after complex I inhibition: Modulation by substrate-dependent regulation of the NADH/NAD+ ratio

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2016.04.002 ◽

2016 ◽

Vol 96 ◽

pp. 22-33 ◽

Cited By ~ 18

Author(s):

Paavo Korge ◽

Guillaume Calmettes ◽

James N. Weiss

Keyword(s):

Reactive Oxygen Species ◽

Complex I ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Oxygen Species ◽

Cardiac Mitochondria ◽

Species Production

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Do semiquinones formed by mitochondrial complex I contribute to reactive oxygen species production?

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/j.bbabio.2010.04.201 ◽

2010 ◽

Vol 1797 ◽

pp. 61-62

Author(s):

Kenneth R. Pryde ◽

Judy Hirst

Keyword(s):

Reactive Oxygen Species ◽

Complex I ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Mitochondrial Complex I ◽

Oxygen Species ◽

Mitochondrial Complex ◽

Species Production

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Site of Mitochondrial Reactive Oxygen Species Production in Skeletal Muscle of Chronic Obstructive Pulmonary Disease and Its Relationship with Exercise Oxidative Stress

American Journal of Respiratory Cell and Molecular Biology ◽

10.1165/rcmb.2011-0382oc ◽

2012 ◽

Vol 47 (3) ◽

pp. 358-362 ◽

Cited By ~ 36

Author(s):

Luis Puente-Maestu ◽

Alberto Tejedor ◽

Alberto Lázaro ◽

Javier de Miguel ◽

Luis ÁLvarez-Sala ◽

...

Keyword(s):

Oxidative Stress ◽

Reactive Oxygen Species ◽

Chronic Obstructive Pulmonary Disease ◽

Skeletal Muscle ◽

Reactive Oxygen Species Production ◽

Chronic Obstructive ◽

Oxygen Species ◽

Mitochondrial Reactive Oxygen Species ◽

Obstructive Pulmonary Disease ◽

Species Production

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The impact of a short-term high-fat diet on mitochondrial respiration, reactive oxygen species production, and dynamics in oxidative and glycolytic skeletal muscles of young rats

Physiological Reports ◽

10.14814/phy2.13548 ◽

2018 ◽

Vol 6 (4) ◽

pp. e13548 ◽

Cited By ~ 13

Author(s):

Jean-Philippe Leduc-Gaudet ◽

Olivier Reynaud ◽

François Chabot ◽

Jocelyne Mercier ◽

David E. Andrich ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Mitochondrial Respiration ◽

High Fat Diet ◽

Skeletal Muscles ◽

Reactive Oxygen Species Production ◽

Oxygen Species ◽

High Fat ◽

Short Term ◽

Species Production ◽

The Impact

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Reactive Oxygen Species Production by Escherichia coli Respiratory Complex I

Biochemistry ◽

10.1021/acs.biochem.5b00160 ◽

2015 ◽

Vol 54 (18) ◽

pp. 2799-2801 ◽

Cited By ~ 7

Author(s):

Klaudia Frick ◽

Marius Schulte ◽

Thorsten Friedrich

Keyword(s):

Escherichia Coli ◽

Reactive Oxygen Species ◽

Complex I ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Oxygen Species ◽

Respiratory Complex ◽

Respiratory Complex I ◽

Species Production

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Increased reactive oxygen species production down-regulates peroxisome proliferator-activated a pathway in C2C12 skeletal muscle cells

Clínica e Investigación en Arteriosclerosis ◽

10.1016/s0214-9168(02)78885-2 ◽

2002 ◽

Vol 14 (6) ◽

pp. 318-319

Author(s):

A. Cabrero ◽

M. Alegret ◽

Rosa M. Sánchez ◽

T. Adzet ◽

A. Pascual ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Skeletal Muscle ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Muscle Cells ◽

Skeletal Muscle Cells ◽

Peroxisome Proliferator ◽

Oxygen Species ◽

C2c12 Skeletal Muscle Cells ◽

Species Production

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Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1111308108 ◽

2011 ◽

Vol 108 (35) ◽

pp. 14608-14613 ◽

Cited By ~ 275

Author(s):

E. Jing ◽

B. Emanuelli ◽

M. D. Hirschey ◽

J. Boucher ◽

K. Y. Lee ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Skeletal Muscle ◽

Insulin Signaling ◽

Reactive Oxygen Species Production ◽

Muscle Metabolism ◽

Oxygen Species ◽

Sirtuin 3 ◽

Skeletal Muscle Metabolism ◽

Mitochondrial Oxidation ◽

Species Production

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Eliminating Nox2 reactive oxygen species production protects dystrophic skeletal muscle from pathological calcium influx assessedin vivoby manganese-enhanced magnetic resonance imaging

The Journal of Physiology ◽

10.1113/jp272907 ◽

2016 ◽

Vol 594 (21) ◽

pp. 6395-6405 ◽

Cited By ~ 10

Author(s):

James A. Loehr ◽

Gary R. Stinnett ◽

Mayra Hernández-Rivera ◽

Wesley T. Roten ◽

Lon J. Wilson ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Reactive Oxygen Species ◽

Skeletal Muscle ◽

Magnetic Resonance ◽

Reactive Oxygen Species Production ◽

Calcium Influx ◽

Reactive Oxygen ◽

Oxygen Species ◽

Resonance Imaging ◽

Species Production

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Mitochondrial NADH redox potential impacts the reactive oxygen species production of reverse Electron transfer through complex I

Journal of Bioenergetics and Biomembranes ◽

10.1007/s10863-018-9767-7 ◽

2018 ◽

Vol 50 (5) ◽

pp. 367-377 ◽

Cited By ~ 8

Author(s):

Hervé Dubouchaud ◽

Ludivine Walter ◽

Michel Rigoulet ◽

Cécile Batandier

Keyword(s):

Reactive Oxygen Species ◽

Electron Transfer ◽

Redox Potential ◽

Complex I ◽

Reactive Oxygen Species Production ◽

Reactive Oxygen ◽

Oxygen Species ◽

Reverse Electron Transfer ◽

Species Production

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