217-LB: A Novel GPR119 Agonist, DA-1241, Improves Hepatic Inflammation and Fibrosis in ob-NASH Mice

216-LB: A Novel GPR119 Agonist, DA-1241, Reduces Hepatic Inflammation and Fibrosis in Preestablished Diet-Induced NASH Mice

Diabetes ◽

10.2337/db20-216-lb ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 216-LB

Author(s):

HANSU PARK ◽

SEUNG HO LEE ◽

MI-KYUNG KIM

Keyword(s):

Hepatic Inflammation ◽

Gpr119 Agonist

Hepatic steatosis induces induction of the chemokine RANTES in the absence of significant hepatic inflammation

10.1055/s-0029-1246351 ◽

2010 ◽

Vol 48 (01) ◽

Author(s):

G Kirovski ◽

C Dorn ◽

TS Weiss ◽

D Schacherer ◽

H Wobser ◽

...

Keyword(s):

Hepatic Steatosis ◽

Impaired intestinal defensin production leads to bacterial translocation and subsequently aggravates hepatic inflammation and fibrogenesis in an experimental NASH model – a new second hit

10.1055/s-0030-1263834 ◽

2010 ◽

Vol 48 (08) ◽

Author(s):

E Gäbele ◽

K Dostert ◽

R Wiest ◽

J Schölmerich ◽

C Hellerbrand ◽

...

Keyword(s):

Bacterial Translocation ◽

Hepatic Inflammation ◽

Second Hit ◽

Nash Model

BMP6 protects against hepatic inflammation and fibrosis in experimental NASH models

10.1055/s-0031-1295731 ◽

2012 ◽

Vol 50 (01) ◽

Author(s):

S Arndt ◽

E Wacker ◽

M Saugspier ◽

C Dorn ◽

C Hellerbrand ◽

...

Keyword(s):

The liver regeneration associated factor ALR attenuates IL-6 induced acute-phase reactants during hepatic inflammation

10.1055/s-0036-1597450 ◽

2016 ◽

Vol 54 (12) ◽

pp. 1343-1404

Author(s):

R Dayoub ◽

L Bürger ◽

S Ibrahim ◽

M Melter ◽

TS Weiss

Keyword(s):

Liver Regeneration ◽

Acute Phase ◽

Hepatic Inflammation ◽

Acute Phase Reactants ◽

Associated Factor

Loss of bile salt export pump (Bsep/Abcb11) aggravates lipopolysaccharide induced hepatic inflammation in mice

10.1055/s-0039-1691935 ◽

2019 ◽

Author(s):

J Remetic ◽

V Mlitz ◽

V Kunczer ◽

H Scharnagl ◽

T Stojakovic ◽

...

Keyword(s):

Bile Salt ◽

Bile Salt Export Pump ◽

1887-P: The GLP-1 Receptor Agonist Liraglutide Improves Hepatic Inflammation and Fibrosis in a Mouse Model of NASH

Diabetes ◽

10.2337/db19-1887-p ◽

2019 ◽

Vol 68 (Supplement 1) ◽

pp. 1887-P

Author(s):

SOPHIE A. MONTANDON ◽

EMMANUEL SOMM ◽

CLAUDIO DE VITO ◽

FRANÇOIS R. JORNAYVAZ

Keyword(s):

Mouse Model ◽

Receptor Agonist ◽

Faculty Opinions recommendation of Synergistic Effects of a GPR119 Agonist with Metformin on Weight Loss in Diet-Induced Obese Mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725388785.793506701 ◽

2015 ◽

Author(s):

John Imig

Keyword(s):

Weight Loss ◽

Synergistic Effects ◽

Obese Mice ◽

Gpr119 Agonist

569 Downregulation of Adiponectin /Adipor2 Is Associated with Hepatic Inflammation and Steatosis in Obese Mice

Gastroenterology ◽

10.1016/s0016-5085(08)63987-6 ◽

2008 ◽

Vol 134 (4) ◽

pp. A-851

Author(s):

Yanhua Peng ◽

Drew A. Rideout ◽

Steven S. Rakita ◽

Mini Sajan ◽

Robert Farese ◽

...

Keyword(s):

Obese Mice ◽

Lycium barbarum polysaccharide combined with aerobic exercise ameliorated nonalcoholic fatty liver disease through restoring gut microbiota, intestinal barrier and inhibiting hepatic inflammation

International Journal of Biological Macromolecules ◽

10.1016/j.ijbiomac.2021.05.066 ◽

2021 ◽

Author(s):

Lu-Lu Gao ◽

Jia-Min Ma ◽

Yan-Na Fan ◽

Yan-Nan Zhang ◽

Rui Ge ◽

...

Keyword(s):

Liver Disease ◽

Gut Microbiota ◽

Fatty Liver ◽

Nonalcoholic Fatty Liver Disease ◽

Fatty Liver Disease ◽

Intestinal Barrier ◽

Hepatic Inflammation ◽

Lycium Barbarum ◽

Nonalcoholic Fatty Liver ◽

Lycium Barbarum Polysaccharide