550-P: Unique Associations of Depressive Symptoms and Diabetes Distress with Quality of Life (QoL) in Youth with Type 1 Diabetes (T1D)

Objective To conduct a systematic review to examine associations between hypoglycemia and quality of life (QoL) in children and adolescents with type 1 diabetes. Methods Four databases (Medline, Cochrane Library, CINAHL, PsycINFO) were searched systematically in November 2019 and searches were updated in September 2021. Studies were eligible if they included children and/or adolescents with type 1 diabetes, reported on the association between hypoglycemia and QoL (or related outcomes), had a quantitative design, and were published in a peer-reviewed journal after 2000. A protocol was registered the International Prospective Register of Systematic Reviews (PROSPERO; CRD42020154023). Studies were evaluated using the Joanna Briggs Institute’s critical appraisal tool. A narrative synthesis was conducted by outcome and hypoglycemia severity. Results In total, 27 studies met inclusion criteria. No hypoglycemia-specific measures of QoL were identified. Evidence for an association between SH and (domains) of generic and diabetes-specific QoL was too limited to draw conclusions, due to heterogenous definitions and operationalizations of hypoglycemia and outcomes across studies. SH was associated with greater worry about hypoglycemia, but was not clearly associated with diabetes distress, depression, anxiety, disordered eating or posttraumatic stress disorder. Although limited, some evidence suggests that more recent, more frequent, or more severe episodes of hypoglycemia may be associated with adverse outcomes and that the context in which hypoglycemia takes places might be important in relation to its impact. Conclusions There is insufficient evidence regarding the impact of hypoglycemia on QoL in children and adolescents with type 1 diabetes at this stage. There is a need for further research to examine this relationship, ideally using hypoglycemia-specific QoL measures.

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Health-related quality of life of preschool-aged children with type 1 diabetes in the context of family and maternal functioning

Journal of Child Health Care ◽

10.1177/1367493521995320 ◽

2021 ◽

pp. 136749352199532

Author(s):

Andrea Lukács ◽

Veronika Bettina Zagraj ◽

Anett Bartkóné Kovács ◽

Andrea Soós ◽

András Török ◽

...

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Depressive Symptoms ◽

Family Functioning ◽

Health Related Quality ◽

The Family ◽

Related Quality ◽

Health Related

In this study, generic health-related quality of life (HRQoL) of young children with type 1 diabetes (T1D) was compared to healthy peers taken in consideration of family functioning and psychological well-being of mothers. A total of 113 mothers provided data (28 mothers had a preschool-aged child with T1D). There were no significant differences in background parameters of two investigated groups. No significant differences between children with and without T1D were detected either in HRQoL or in family functioning. Moreover, mothers of children with diabetes reported lower levels of resilience and more depressive symptoms than mothers of healthy peers. In the regression analysis, mothers’ depressive symptoms and the family functioning significantly affected children’s HRQoL regardless of the presence of diabetes. These results suggest that parents of children with T1D handle the burden of diabetes well and integrate into the daily activities of the families. Mothers experience distress, presumably because diabetes management is burdensome; however, the family can function well and the young children can live in a similar way to their healthy peers.

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Adolescents with poorly controlled type 1 diabetes: Psychological flexibility is associated with the glycemic control, quality of life and depressive symptoms

Journal of Contextual Behavioral Science ◽

10.1016/j.jcbs.2020.12.003 ◽

2021 ◽

Vol 19 ◽

pp. 50-56

Author(s):

Alho Iina ◽

Joro Mirka ◽

Juntunen Laura ◽

Muotka Joona ◽

Lappalainen Raimo

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Depressive Symptoms ◽

Glycemic Control ◽

Psychological Flexibility ◽

Control Quality

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Validation of the Healthcare Transition Outcomes Inventory for Young Adults With Type 1 Diabetes

Journal of Pediatric Psychology ◽

10.1093/jpepsy/jsaa051 ◽

2020 ◽

Vol 45 (7) ◽

pp. 767-779

Author(s):

Jessica Pierce ◽

Jobayer Hossain ◽

Anthony Gannon

Keyword(s):

Quality Of Life ◽

Type 1 Diabetes ◽

Young Adults ◽

Glycemic Control ◽

Psychometric Properties ◽

Diabetes Distress ◽

Transition Outcomes ◽

Healthcare Transition

Abstract Objective We recently developed and content validated the Healthcare Transition Outcomes Inventory (HCTOI), a stakeholder vetted, multidimensional measure of the outcomes of the transition from pediatric to adult healthcare for young adults (YA) with type 1 diabetes (T1D). In this study, we aimed to evaluate the psychometric properties of the HCTOI. Methods We collected and analyzed cross-sectional data from 128 YA (18–25 years old) with T1D to evaluate the psychometric properties of the HCTOI. We conducted confirmatory factor analysis (CFA), item analysis, and examined reliability and validity in relation to measures of quality of life, diabetes distress, regimen adherence, and glycemic control. Results CFA supported a five-factor solution: integration of T1D into emerging adult roles, balance of parental support with T1D autonomy, establishing and maintaining continuity of care, forming a collaborative patient–provider relationship, and ownership of T1D. We reduced the HCTOI from 54 to 34 items. The HCTOI demonstrated adequate internal consistency (α’s = 0.62–0.87) and significant correlations demonstrated construct (quality of life, diabetes distress) and criterion validity (adherence, glycemic control). Conclusions The HCTOI demonstrated promising initial psychometric properties. As the first measure of the multiple dimensions of healthcare transition outcomes, the HCTOI provides a means to examine longitudinal relations between transition readiness and outcomes and to assess the efficacy or effectiveness of interventions and programs designed to improve the transition process for YA with T1D.

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