scholarly journals Dose-Dependent Delay of the Hypoglycemic Effect of Short-Acting Insulin Analogs in Obese Subjects With Type 2 Diabetes: A pharmacokinetic and pharmacodynamic study

Diabetes Care ◽  
2010 ◽  
Vol 33 (12) ◽  
pp. 2502-2507 ◽  
Author(s):  
M. Gagnon-Auger ◽  
P. du Souich ◽  
J.-P. Baillargeon ◽  
E. Martin ◽  
P. Brassard ◽  
...  
2017 ◽  
Vol 10 (1) ◽  
pp. 38 ◽  
Author(s):  
Inayah Inayah ◽  
M. Yulis Hamidy ◽  
Roza Putri Rachma Yuki

Insulin is one of pharmacological treatment of type 2 diabetes mellitus (DM). The aim of this study was to know thepattern of insulin use in hospitalized patients with type 2 diabetes Hospital X Pekanbaru. The type of research wasdescriptive. Data retrieved from 63 the medical records of patients with type 2 diabetes at Hospital X Pekanbaruperiod January - December 2014. The most characteristics of subject was average of age 55.40 (± 10.91) years, theaverage of RBG level 313.37 (± 135.81) mg / dL, female (55.6%), financing with BPJS (49.2%), housewives (49.2%),the diagnosis of type 2 diabetes with complications (38.1 %). The most insulin usage according to duration of actionwas short-acting insulin (46.4%), the number of daily doses was <20 IU from all type of insulin. The most combinationof different insulin types (7.9%) was long-acting insulin with rapid-acting insulin and the most combination of insulinand OHD (6.3%) was a short-acting insulin with gluconeogenesis inhibitor and premixed insulin with gluconeogenesisinhibitor.


Cureus ◽  
2020 ◽  
Author(s):  
Mahmood Thamer Altemimi ◽  
Samih A Odhaib ◽  
Husam J Imran ◽  
Ali Alhamza ◽  
Ammar M Almomin ◽  
...  

2011 ◽  
Vol 14 (4) ◽  
pp. 46-50
Author(s):  
Elena Valer'evna Biryukova

Current possibilities for the use of ultra-short acting insulin analogs are discussed. The importance of control of postprandial hyperglycemia is emphasized.Pharmacological properties of insulin glulisine are described with special reference to its advantage over human ultra-short acting insulin.An important characteristic of glulisine is the possibility of its efficacious use for the treatment of obese patients. The results of GINGER and CHOinternational studies suggest high efficacy and safety of glulisine used for intensive insulin therapy according to both flexible and fixed regimens.


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