Improving motor recovery after cortical stroke using cerebellar non-invasive transcranial stimulation

2021 ◽  
Vol 112 (3) ◽  
Author(s):  
Rebeca B. CECATTO ◽  
Linamara R. BATTISTELLA
2019 ◽  
Vol 30 (8) ◽  
pp. 821-837 ◽  
Author(s):  
Sharon Israely ◽  
Gerry Leisman

Abstract Individuals post-stroke sustain motor deficits years after the stroke. Despite recent advancements in the applications of non-invasive brain stimulation techniques and Deep Brain Stimulation in humans, there is a lack of evidence supporting their use for rehabilitation after brain lesions. Non-invasive brain stimulation is already in use for treating motor deficits in individuals with Parkinson’s disease and post-stroke. Deep Brain Stimulation has become an established treatment for individuals with movement disorders, such as Parkinson’s disease, essential tremor, epilepsy, cerebral palsy and dystonia. It has also been utilized for the treatment of Tourette’s syndrome, Alzheimer’s disease and neuropsychiatric conditions such as obsessive-compulsive disorder, major depression and anorexia nervosa. There exists growing scientific knowledge from animal studies supporting the use of Deep Brain Stimulation to enhance motor recovery after brain damage. Nevertheless, these results are currently not applicable to humans. This review details the current literature supporting the use of these techniques to enhance motor recovery, both from human and animal studies, aiming to encourage development in this domain.


2012 ◽  
Vol 55 ◽  
pp. e151-e152
Author(s):  
I. Loubinoux ◽  
L. Vaysse ◽  
A. Béduer ◽  
F. Seichepine ◽  
E. Flahaut ◽  
...  

2010 ◽  
Vol 5 (2) ◽  
pp. 67
Author(s):  
Rüdiger J Seitz ◽  
Robert Lindenberg ◽  
Gottfried Schlaug ◽  
◽  
◽  
...  

Human ischaemic stroke is a multistage disorder with various routes of recovery. Neuroimaging allows researchers to explore the pathophysiology and recovery mechanismsin vivo. Based on these findings, motor recovery and chronic motor impairment after stroke have been linked to structural alterations of grey and white matter as well as functional changes in the perilesional tissue. Parameters derived from diffusion tensor imaging and functional magnetic resonance imaging can be used as surrogate markers of chronic motor impairment and predictors of functional potential for motor recovery. These parameters have the potential to tailor individual rehabilitation and stratify patients for experimental therapy studies such as invasive and non-invasive brain stimulation alone or in combination with other facilitators.


US Neurology ◽  
2010 ◽  
Vol 06 (02) ◽  
pp. 105 ◽  
Author(s):  
Rüdiger J Seitz ◽  
Robert Lindenberg ◽  
Gottfried Schlaug ◽  
◽  
◽  
...  

Human ischemic stroke is a multistage disorder with various routes of recovery. Neuroimaging allows researchers to explore the pathophysiology and recovery mechanismsin vivo. Based on these findings, motor recovery and chronic motor impairment after stroke have been linked to structural alterations of grey and white matter as well as functional changes in the perilesional tissue. Parameters derived from diffusion tensor imaging and functional magnetic resonance imaging can be used as surrogate markers of chronic motor impairment and predictors of functional potential for motor recovery. These parameters have the potential to tailor individual rehabilitation and stratify patients for experimental therapy studies such as invasive and non-invasive brain stimulation alone or in combination with other facilitators.


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