Impact of Adherence to a Full Course of Intermittent Preventive Treatment of Malaria in Pregnancy on Pregnancy Outcome in Muyuka Health District: A Cross-Sectional Study

In 2012 the World Health Organisation (WHO) revised the policy on Intermittent Preventive Treatment with Sulphadoxine Pyrimethamine (IPTp-SP) to at least three doses for improved protection against malaria parasitaemia and its associated effects such as anaemia during pregnancy. We assessed the different SP dosage regimen available under the new policy to determine the dose at which women obtained optimal protection against anaemia during pregnancy. A cross-sectional study was conducted among pregnant women who attended antenatal clinic at four different health facilities in Ghana. The register at the facilities served as a sampling frame and simple random sampling was used to select all the study respondents; they were enrolled consecutively as they kept reporting to the facility to receive antenatal care to obtain the required sample size. The haemoglobin level was checked using the Cyanmethemoglobin method. Multivariable logistic regression was performed to generate odds ratios, confidence intervals and p-values. The overall prevalence of anaemia among the pregnant women was 62.6%. Pregnant women who had taken 3 or more doses of IPTp-SP had anaemia prevalence of 54.1% compared to 66.6% of those who had taken one or two doses IPTp-SP. In the multivariable logistic model, primary (aOR 0.61; p = 0.03) and tertiary education (aOR 0.40; p = <0.001) decreased the odds of anaemia in pregnancy. Further, pregnant women who were anaemic at the time of enrollment (aOR 3.32; p = <0.001) to the Antenatal Care clinic and had malaria infection at late gestation (aOR 2.36; p = <0.001) had higher odds of anaemia in pregnancy. Anaemia in pregnancy remains high in the Northern region of Ghana. More than half of the pregnant women were anaemic despite the use of IPTp-SP. Maternal formal education reduced the burden of anaemia in pregnancy. The high prevalence of anaemia in pregnancy amid IPTp-SP use in Northern Ghana needs urgent attention to avert negative maternal and neonatal health outcomes.

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Prevalence of HBsAg and knowledge about hepatitis B in pregnancy in the Buea Health District, Cameroon: a cross-sectional study

BMC Research Notes ◽

10.1186/1756-0500-7-394 ◽

2014 ◽

Vol 7 (1) ◽

pp. 394 ◽

Cited By ~ 33

Author(s):

Andreas A Frambo ◽

Julius Atashili ◽

Peter Fon ◽

Peter Ndumbe

Keyword(s):

Hepatitis B ◽

Cross Sectional Study ◽

Health District ◽

Sectional Study ◽

Cross Sectional ◽

In Pregnancy

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The economic burden of malaria in pregnancy: a cross-sectional study

The Journal of Maternal-Fetal & Neonatal Medicine ◽

10.1080/14767058.2018.1487933 ◽

2018 ◽

Vol 33 (1) ◽

pp. 92-95

Author(s):

Vivian Uchenna Onyia ◽

Maduka Donatus Ughasoro ◽

Obinna Emmanuel Onwujekwe

Keyword(s):

Economic Burden ◽

Cross Sectional Study ◽

Malaria In Pregnancy ◽

Sectional Study ◽

Cross Sectional ◽

In Pregnancy

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Asymptomatic malaria and its effect on parturients who received intermittent preventive treatment, a cross sectional study of the Bekwai District Ghana

GSC Biological and Pharmaceutical Sciences ◽

10.30574/gscbps.2018.4.2.0054 ◽

2018 ◽

Vol 4 (2) ◽

pp. 007-016 ◽

Cited By ~ 3

Author(s):

Gideon Darko Asamoah ◽

Darko Gideon ◽

Fred Jonathan Edzeamey ◽

Richard KD Ephraim ◽

Bernard Berko Sampong ◽

...

Keyword(s):

Intermittent Preventive Treatment ◽

Preventive Treatment ◽

Cross Sectional Study ◽

Asymptomatic Malaria ◽

Sectional Study ◽

Cross Sectional

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Knowledge and Perceived Barriers towards Intermittent Prevention of Malaria in Pregnancy: A Cross-Sectional Study

Open Journal of Internal Medicine ◽

10.4236/ojim.2021.111002 ◽

2021 ◽

Vol 11 (01) ◽

pp. 27-38

Author(s):

Frank Bediako Agyei ◽

Gideon Dzando ◽

Anthony B. Donyi ◽

Elisha A. Nonoh ◽

Rebecca Dordunu ◽

...

Keyword(s):

Cross Sectional Study ◽

Malaria In Pregnancy ◽

Perceived Barriers ◽

Sectional Study ◽

Cross Sectional ◽

In Pregnancy

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Factors Associated with Anemia in Pregnancy in Cascades Region in Burkina Faso

European Journal of Nutrition & Food Safety ◽

10.9734/ejnfs/2015/21018 ◽

2015 ◽

pp. 663-664

Author(s):

Ilboudo Bernard ◽

Savadogo G. Léon Blaise ◽

Kinda Maurice ◽

Guiguemde T. Robert ◽

Dramaix-wilmet Michèle ◽

...

Keyword(s):

Burkina Faso ◽

Pregnant Women ◽

Intermittent Preventive Treatment ◽

Preventive Treatment ◽

Cross Sectional Study ◽

Cross Sectional ◽

Factors Associated ◽

Anemia In Pregnancy ◽

Prevalence Of Anemia ◽

In Pregnancy

Objectives: To analyze the factors associated with anemia in pregnancy in the Cascades region in Burkina Faso. Methods: A cross-sectional study was carried out in antenatal clinics of the Cascades region in Burkina Faso during one month from May to June 2012. We collected data on socio-demographics and health characteristics of pregnant women attending these clinics. Hemoglobin was measured to assess anemia. Factors associated with anemia were identified through a multivariate analysis. Results: A total of 1763 pregnant women, irrespectively of pregnancy stage, were enrolled. The mean (SD) hemoglobin level was 10.6 (1.4) g/dl. The prevalence of anemia in pregnancy was 58.9%, 3.2% of them being severe. Factors associated with anemia were the absence of intermittent preventive treatment of malaria with sulfadoxin-pyrimetamin (OR = 1.3, 95% CI: 1.0-1.7), number of pregnancies >6 (OR = 1.4, 95% CI: 1.1-1.9). Moderate consumption of local alcohol extracted from Palmyra was associated with a lower prevalence of anemia (OR = 0.7, 95% CI: 0.5-0.9). Surprisingly, anemia was not associated with supplementation with folic acid + iron (p = 0.60). Conclusions: Interventions which aim to reduce the prevalence of anemia in pregnancy in Burkina Faso should improve the coverage of the intermittent preventive treatment of malaria and support the limitation of births.

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Factors Influencing Adherence to the New Intermittent Preventive Treatment of Malaria in Pregnancy Policy in Keta District of the Volta Region, Ghana

10.21203/rs.2.11602/v3 ◽

2019 ◽

Author(s):

Alren O. Vandy ◽

Nana Yaw Peprah ◽

Joseph Yaw Jerela ◽

Perfect Titiati ◽

Abubakar Manu ◽

...

Keyword(s):

Intermittent Preventive Treatment ◽

Preventive Treatment ◽

Malaria In Pregnancy ◽

World Health ◽

Categorical Variables ◽

Chi Square ◽

Cross Sectional ◽

Factors Influencing ◽

Volta Region ◽

In Pregnancy

Abstract Background About 25% of pregnant women in malaria endemic areas are infected with malaria and this accounts for about 15% of maternal death globally. Intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is one of the main strategies for prevention of malaria in pregnancy. A new recommendation was made by World Health Organization (WHO) that at least three doses of IPTp-SP should be administered before delivery. This study sought to determine the factors influencing adherence to the new IPTp-SP policy in Keta District, Volta region, Ghana. Methods A cross-sectional quantitative study among 375 nursing mothers at four selected health facilities in Keta district, Ghana was conducted using a structured questionnaire to interview participants. Data was analyzed using STATA 15. Chi-square was used to test bivariate association between categorical variables and adherence. Logistic regression analysis was used to examine sociodemographic, individual and institutional factors influencing adherence to IPTp-SP. Result About 82.1% of participants adhered to the WHO policy recommendations of at least three doses of IPTp-SP. However, only 17.1% received Ghana’s five dose coverage recommendation. The proportion of IPTp-SP coverage for IPTp1 was 98.9%; IPTp2 95.5%; IPTp3 80.8%; IPTp4 39.5%; IPTp5 17.1%. Conclusion Adherence to IPTp-SP was satisfactory according to WHO’s policy recommendation, however, majority of the participants had less than the five doses recommended in Ghana. Number of ANC visits and knowledge of malaria were the main determinants of adherence to IPTp-SP.

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Factors Associated with Uptake of Intermittent Preventive Treatment of Malaria in Pregnancy: A Cross-Sectional Study in Private Health Facilities in Tema Metropolis, Ghana

Journal of Tropical Medicine ◽

10.1155/2019/9278432 ◽

2019 ◽

Vol 2019 ◽

pp. 1-11 ◽

Cited By ~ 5

Author(s):

Selina Amankwah ◽

Francis Anto

Keyword(s):

Antenatal Care ◽

Intermittent Preventive Treatment ◽

Preventive Treatment ◽

Health Facilities ◽

Malaria In Pregnancy ◽

Second Trimester ◽

Cross Sectional ◽

Factors Associated ◽

Postnatal Women ◽

In Pregnancy

Introduction. Intermittent preventive treatment of malaria in pregnancy with sulfadoxine pyrimethamine (IPTp-SP) is effective in preventing the adverse consequences of malaria on birth outcomes. Methods. A cross-sectional survey was carried out among antenatal and postnatal women and midwives at private health facilities in Tema using the mixed method to investigate factors associated with uptake of IPTp-SP. Antenatal and postnatal women were consecutively enrolled and data on their sociodemographic characteristics and antenatal service utilization collected using a questionnaire and review of antenatal care (ANC) records. In-depth interviews involving attending midwives were conducted and data on ANC service delivery collected. The interviews were manually analyzed. Bivariate and multiple logistic regression analyses were done to determine factors associated with uptake of SP. Results. Of the 382 respondents, 178 (46.6%) took ≥ 3 doses of SP. Uptake was similar for those who had delivered and those yet to deliver (χ2 =2.94, p > 0.05). Ninety-seven of the 176 (55.1%) women who initiated antenatal visit during the first trimester received ≥ 3 doses of SP whilst 42.0% (76/181) of those who started during the second trimester received ≥ 3 doses (χ2 = 5.64, p = 0.02). Those who initiated ANC during the second trimester received more doses compared to those who started during the third trimester (χ2 = 4.43, p = 0.04). Respondents who attended ANC > 5 times increased their uptake by 83% compared to those who attended < 5 times (OR 0.2, 95% C.I 0.12-0.31). There was poor adherence to directly observed treatment and low knowledge of midwives on IPTp-SP protocol. Conclusion. Early initiation and regular visit to antenatal care centres promoted uptake of optimal doses of SP.

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