scholarly journals Interpretation of Modified Glucose Tolerance Test among Pregnant Malaysian Women

2020 ◽  
Vol 5 (08) ◽  
pp. 309-313
Author(s):  
Muna Kh. Al-kubaisi ◽  
Saad M. Al-Shibli ◽  
Nilar Win
Keyword(s):  
Glucose Tolerance ◽  
Pregnant Women ◽  
Blood Sample ◽  
Blood Sugar ◽  
Glucose Tolerance Test ◽  
Venous Blood ◽  
Tolerance Test ◽  
Oral Glucose ◽  
The Mean ◽  
Local Protocol

Aim: Is to find the mean and two standard deviation of the serum blood sugar among pregnant women while running the modified oral glucose tolerance test (MOGTT) as screening for gestational diabetes mellitus (GDM) & to compare the readings with other protocols adopted in diagnosing GDM. Method: A cross sectional study among pregnant women running routine MOGTT at 24-28 weeks’ gestation. A total of 149 women participated in 4 months period. The test included 5 ml of venous blood sample taken after fasting for 8 hours and a second blood sample 2 hours after having 200 ml of 75 g glucose solution within 10 minutes. Results: The mean for the fasting blood sugar is 4.32 mmol/L±0.52 making value of 2SD of 5.36 mmol/l. The mean of the 2 hours glucose level was 6.11mmol/l±1.38 making the 2SD value of 8.87 mmol/l. Conclusion: Our results for the 1st reading in MOGTT is near to the value of the local protocol in diagnosing GDM. The 2 hours postprandial reading in the local protocol is fairly low when compared with our findings & with guidelines of nearby communities.

scholarly journals Effects of commonly consumed traditional fortified staple meals on the postprandial blood glucose responses of undergraduate students in Imo State University, Owerri, Imo State, Nigeria: an open-label study

2016 ◽  
Vol 6 (7) ◽  
pp. 414
Author(s):  
Chinagorom Asinobi ◽  
Henritta Uzoagba ◽  
Angela Mba-Anyadioha ◽  
Nnodim Johnkennedy
Keyword(s):  
Blood Glucose ◽  
Blood Sugar ◽  
Undergraduate Students ◽  
Glycemic Index ◽  
Test Meal ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Postprandial Blood Glucose ◽  
Oral Glucose ◽  
The Mean

Background: Diabetics Mellitus a chronic metabolic disorder that prevents the body to utilize glucose completely or partially requires low caloric diets. Unfortunately, Nigerian traditional menu is based on starchy foods. Many diabetic individuals had been ignorantly oriented to consume some staple foods that are believed to have lower calorie than others for low blood glucose response.The study is focused on determining the glycemic index of commonly consumed fortified staple foods as well as determining the extent of their effects on the postprandial blood glucose responses of undergraduate students.Methods: Fifteen volunteered non- diabetic undergraduate students aged 20 – 25yrs on which standard oral glucose tolerate test was performed were selected and were asked to report at the study centre each day after overnight fasting (10 – 12hrs) with certain precautions by 8am for a period of 5days for different prepared test meals from the commonly consumed fortified staple food; namely; beans stew, rice stew, yam stew, unripe plantain stew and garri and stew. Fasting blood samples (2ml each) were collected from the prominent arm veins of each student prior to the eating of one of the test meals on each day. Each test meal contains 50g carbohydrate portion per meal. After the meals had been eaten, 2ml venous blood samples were collected at 30minutes interval for 120 minutes each day from each student and put into the specimen bottles for blood glucose estimations. Also the random sugar was determined 2hours later. A glucometer was used for measuring the blood sugar using test strips. The mean values of postprandial glucose blood sugar for each test meals for the selected students were obtained.Results: The glycemic index of the commonly consumed fortified staple test meals was highest in rice stew (107.7± 8.4), followed by yam stew (102.4±1.8), garri and stew (101.4±11.8), beans stew (86.9±6.7), and unripe plantain stew (81.8±8.4) in that order. The carbohydrate content of the commonly consumed fortified staple test meals was highest in garri with soup (68.2±0.2g) and lowest in unripe plantain stew while the fibre content was highest in plantain stew (5.8±0.4g) and lowest in rice stew (2.8±0.12g). The mean blood oral glucose tolerance test of the students was below 100mg/dl but has the mean peak after an hour interval (112.8±7.3mg/dl) the test food meals were ingested.The highest increase on the postprandial blood glucose after ingestion of the test meals was highest for garri and stew test meal (97.2±14.7mg/dl) but lowest for unripe plantain stew meal (85.574.3±11.6mg/dl) after 60 minutes the test meals were ingested.The random blood sugar test was highest in garri and soup (93.1±2.4mg/dl), followed by beans stew (88.4±4.9mg/dl), and lowest in plantain stew (74.3±11.6mg/dl) test meals after 2hrs the test meals were ingested.Conclusion: Unripe plantain stew meal had the lowest glycemic index response, with lowest postprandial blood glucose response after for the period of time the test meal were ingested.. This could be attributed to the relatively higher level of fibre content of the unripe plantain than other test meals.Key Words: glycemic index, postprandial blood glucose concentrations, glucose tolerance test   

scholarly journals TNFα Dynamics During the Oral Glucose Tolerance Test Vary According to the Level of Insulin Resistance in Pregnant Women

2014 ◽  
Vol 99 (5) ◽  
pp. 1862-1869 ◽  
Author(s):  
Laetitia Guillemette ◽  
Marilyn Lacroix ◽  
Marie-Claude Battista ◽  
Myriam Doyon ◽  
Julie Moreau ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Pregnant Women ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance

GLUCOSE TOLERANCE, INSULIN AND GROWTH HORMONE IN INFANTS OF GESTATIONAL DIABETIC MOTHERS

PEDIATRICS ◽  
1970 ◽  
Vol 45 (3) ◽  
pp. 394-403
Author(s):  
Harold S. Cole ◽  
Joan H. Bilder ◽  
Rafael A. Camerini-Davalos ◽  
Richard D. Grimaldi
Keyword(s):  
Growth Hormone ◽  
Glucose Tolerance ◽  
Oral Glucose Tolerance Test ◽  
Normal Control ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
The Mean ◽  
Diabetic Mothers

Twelve control and nine gestational diabetic mothers (GDM) and their infants were studied at birth. All GDM were obese. The criteria for selection of control mothers were a negative family history for diabetes, a normal oral glucose tolerance test, and the presence of obesity. The mean birth weights of the infants were not significantly different. All infants received a 3-hour oral glucose tolerance test (OGTT), completed within the first 24 hours of life. Glucose, serum immunoreactive insulin and growth hormone levels were determined. The mean glucose values obtained at the time of delivery revealed no significant differences between the GDM and the control mothers or between the infants of gestational diabetic mothers (IGDM) and the normal control infants. At birth, the mean seruni insulin levels of the GDM and the IGDM were both significantly higher than were their control GDM and IGDM. The OGTT was performed between 0 and 21 hours after birth and after a 4-hour fast. The mean fasting blood glucose level of the IGDM was significantly lower than that of the control infants, p≤.02. However, during the OGTT, the normal control infants showed a disposal of glucose similar to the IGDM. No evidence of hyperinsulinemia was observed in either the control infants or the infants of gestational diabetic mothers. The mean growth hormone values for the infants at the time of delivery revealed no significant differences between the two study groups. During the OGTT, the IGDM had significantly higher mean growth hormone values at both 60 and 120 minutes.

Effects of metformin and insulin therapy regimens on postpartum oral glucose tolerance test results in pregnant women with gestational diabetes mellitus: a comparative study

2020 ◽  
Vol 41 (4) ◽  
Author(s):  
Moghadaseh Jahanshahi ◽  
Arash Rezaei Shahmirzadi ◽  
Elham Kashani ◽  
Reza Alipoor ◽  
Shoreh Vosough
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Glucose Tolerance ◽  
Insulin Therapy ◽  
Pregnant Women ◽  
Glucose Tolerance Test ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Maternal Weight

AbstractObjectivesThe main purpose of this study was to compare the effects of two regimens of metformin and insulin therapy on postpartum oral glucose tolerance test (OGTT) results in pregnant women with gestational diabetes mellitus (GDM).MethodsIn this single-blind randomized clinical trial (RCT), a total number of 60 pregnant women meeting the inclusion criteria were assigned to two groups with a randomized block design (RBD): insulin therapy (IT) group (30 patients) and metformin therapy (MT) group (30 patients). At baseline, the data were comprised of prenatal maternal age, gestational age, GDM diagnosis, and maternal weight/height. During the postpartum period, 5-cc blood samples were taken from the pregnant women concerned to analyze their fasting blood sugar (FBS) levels. Then, the patients were asked to come back four days and six weeks later after delivery to check the OGTT results. At six weeks postpartum, in addition to OGTT, the glycated hemoglobin (HbA1C) test was performed for all mothers. Finally, six weeks after delivery, these mothers were evaluated with regard to weight loss and body mass index (BMI).ResultsSix weeks postpartum, the maternal weight and BMI significantly decreased in the MT group compared with the IT one, while there was no significant difference between both groups at baseline. On the fourth day, the OGTT results in the MT group were significantly lower in comparison with those in the IT group (p=0.012). At sixth weeks postpartum, the OGTT results were comparably lower in the MT group than those reported for the IT one; however, such a difference was not statistically significant (p=0.087).ConclusionsAccording to the study results, metformin could be an effective and safe treatment for pregnant women suffering from GDM instead of insulin therapy.

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