Recurrent miscarriage is one of the main problems of obstetrics, gynecology and reproductive medicine. The incidence of recurrent misscarriage is fairly high, with most cases of abortion occurring at I trimester, and the true cause is difficult to establish. The aim of the work is to find out the predictors of early reproductive losses in women with a history of habitual miscarriage. The study included 88 women with a habitual miscarriage (the main group) and 50 women with a physiological course of I trimester of gestation (control group). The study was carried out on the basis of the Vinnitsa maternity hospital No. 2. The following research methods were used: clinical, instrumental, mathematical-statistical. Methods of research: clinical, laboratory, biochemical, instrumental, fluorescence spectroscopy, mathematical and statistical methods. According to the results of the retrospective analysis of women with the usual miscarriage during the period from 2009 to 2016 it was found that their number is approximately the same every year. Although in 2015, the proportion of non-pregnancy cases was the smallest (10.68%) compared with 2013 (18.29%) (p=0.008), the share of women with this pathology continued to increase. During the ultrasound assessment of the blood flow in the uterine vessels, it was found that the index of resistance and pulsation index in women of the main group was lower than that of control group women. It was also found that there was a strong direct correlation between certain blood flow parameters in uterine arteries and spiral arteries. So, conducting an ultrasound study for all women with a history of unexplained pregnancy and detecting changes in the blood flow in the uterine vessels will enable us to predict the pathology of placenta in the early stages, and to timely correct the findings.
Estimation of the blood flow in the uterine vessels and extraembryo structures in early gestation