Comparative Levels of Serum Cardiac Parameters at Different Time Periods of Acute Myocardial Infarction – A Time Frame Study

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
N Girerd ◽  
C Meune ◽  
K Duarte ◽  
V Vercamer ◽  
M Lopez-Sublet ◽  
...  

Abstract Background Despite widespread investigation into the incidence of acute myocardial infarction during the COVID-19 pandemic and associated lockdown, no study has examined the situation's impact on blood pressure (BP) levels. Methods Measurements of BP and heart rate (HR) were obtained from persons living in the Paris urban area using connected home BP monitors (accessible to patients and health providers through a secured server). Three time periods of e-Health recordings were compared: during the pandemic prior to the lockdown, during the lockdown and the same time period in 2019. Results A total of 297,089 BP recordings from 2,273 participants (age 56.3±12.8 years, 81.1% male) were made. During confinement, systolic BP gradually decreased by 3 mmHg (−2.4 to −3.9), and diastolic BP, by 1.5 mmHg (−1.4 to −2.2) (all p<0.001); this decrease was greater for participants with higher BP (p<0.0001 each). No significant variation in HR was noted. Conclusion Among a very large cohort, we observed a significant decrease in home BP measured with e-Health devices during the first lockdown period. This study emphasizes the research potential of e-Health during the Covid crisis. FUNDunding Acknowledgement Type of funding sources: None. Changes in BP during the French Lockdown


2019 ◽  
Vol 25 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Kenan Yalta ◽  
Mehmet Birhan Yilmaz ◽  
Tulin Yalta ◽  
Orkide Palabiyik ◽  
Gokay Taylan ◽  
...  

In the setting of acute myocardial infarction (AMI), adverse myocardial remodeling (AMR) has been universally regarded as an early-onset phenomenon generally arising within the first few weeks (usually within days in the infarct zone) following myocardial injury. On the other hand, onset of cardiac morphological changes in this setting may potentially extend far beyond this time frame (usually beyond several months after the index AMI), suggesting a prolonged latent period in certain cases. In clinical practice, this delayed form of post-AMI remodeling, namely late AMR, has emerged as an interesting and underrecognized phenomenon with poorly understood mechanisms. Notably, systemic inflammation and associated growth factors seem to play a pivotal role in this setting. Accordingly, the present article primarily aims to discuss potential mechanisms and clinical implications of late AMR (in a comparative manner with its classical early counterpart) among AMI survivors along with a particular emphasis on potential benefits of certain anti-inflammatory strategies in this setting.


2007 ◽  
Vol 119 (3) ◽  
pp. 319-325 ◽  
Author(s):  
Ann-Marie Svensson ◽  
Mikael Dellborg ◽  
Putte Abrahamsson ◽  
Thomas Karlsson ◽  
Johan Herlitz ◽  
...  

Author(s):  
Masahiro Ono ◽  
Kaoru Aihara ◽  
Gompachi Yajima

The pathogenesis of the arteriosclerosis in the acute myocardial infarction is the matter of the extensive survey with the transmission electron microscopy in experimental and clinical materials. In the previous communication,the authors have clarified that the two types of the coronary vascular changes could exist. The first category is the case in which we had failed to observe no occlusive changes of the coronary vessels which eventually form the myocardial infarction. The next category is the case in which occlusive -thrombotic changes are observed in which the myocardial infarction will be taken placed as the final event. The authors incline to designate the former category as the non-occlusive-non thrombotic lesions. The most important findings in both cases are the “mechanical destruction of the vascular wall and imbibition of the serous component” which are most frequently observed at the proximal portion of the coronary main trunk.


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