scholarly journals Anti-Inflammatory and anti-arthritic activity of ethanolic extract of stem bark of saraca asoca

2020 ◽  
Vol 10 (3) ◽  
Keyword(s):  
Ethanolic Extract ◽  
Stem Bark ◽  
Saraca Asoca ◽  
Anti Inflammatory

scholarly journals Antinociceptive and Anti-inflammatory Activities of the Ethanolic Extract, of Fractions and of Epicatechin Isolated from the Stem Bark of Ximenia americana L. (Oleacaceae)

2018 ◽  
Vol 10 (1) ◽  
pp. 86-101
Author(s):  
Thays de L. M. F. Dias ◽  
Gabriela M. A. Melo ◽  
Yolanda K. C. da Silva ◽  
Aline C. de Queiroz ◽  
Henrique F. Goulart ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Stem Bark ◽  
Ximenia Americana ◽  
Anti Inflammatory

scholarly journals Antibacterial, Antioxidant and Anti-Inflammatory Potential of the Different Extracts of Holoptelia Integrifolia

2019 ◽  
Vol 9 (2) ◽  
pp. 5234-5240
Keyword(s):  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Inflammatory Activity ◽  
Diffusion Method ◽  
Albino Rats ◽  
Nitric Oxide Radical ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

Medicinal plants are play significant impact in the personal medicine for most of the people all over the world as an alternative live saving medicines and most of their medicinal properties are well known for anticancer activity. The different extracts of Holoptelea integrifolia (H.integrifolia) leaves, stem bark and fruits were studied as a potent natural source of antimicrobial, antioxidant and wound healing potential. This work was carried out to evaluate antimicrobial, antioxidant and anti-inflammatory activity of different extracts of H.integrifolia. The antimicrobial activity of the H.integrifolia ethanolic extract was studied against five fungal and bacterial strains by utilizing the agar well diffusion method and MIC. Among several strain, the ethanolic extract of fruit has shown higher antimicrobial inhibition zone as 9.25-16 mm compare to other two extracts of stem and leaves as 10- 13.25 mm and 6-10.2 mm respectively. The antioxidant activities for different extract were also determined by DPPH free radical assay, Hydroxyl Radical Scavenging and Nitric Oxide Radical Scavenging Activity method. The anti-inflammatory activity also estimated basedon formalin induced paw edema method on Wistar albino rats. The different extracts of leaves, stem bark and fruit parts of Holoptelea integrifolia were estimated for in vivo anti-inflammatory activity against the animal model of female Wistar albino rats. The results of anti-inflammatory activity revealed that the Ethanol extracts showed vital and dose-dependent anti-inflammatory effects. Our findings revealed that aerial parts of H.integrifolia contais potential antimicrobial, antioxidant and anti-inflammatory compounds, which expose the medicinal potential of the selected plant could be a significant drug candidates against microbial, oxidative and inflammation-related pathological processes as a future alternative medicine.

scholarly journals Antinociceptive and anti-inflammatory effects of a Geissospermum vellosii stem bark fraction

2016 ◽  
Vol 88 (1) ◽  
pp. 237-248 ◽  
Author(s):  
JOSÉLIA A. LIMA ◽  
THIAGO W.R. COSTA ◽  
LEANDRO L. SILVA ◽  
ANA LUÍSA P. MIRANDA ◽  
ANGELO C. PINTO
Keyword(s):  
Formalin Test ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Second Phase ◽  
Murine Models ◽  
Hot Plate Test ◽  
Rat Paw Edema ◽  
Anti Inflammatory ◽  
Rat Paw ◽  
Abdominal Constriction

ABSTRACT Geissospermum vellosii (Pao pereira) is a Brazilian tree whose stem barks are rich in indole alkaloids that present intense anticholinesterase activity. The present study evaluated the effects of a stem bark fraction (PPAC fraction) and ethanolic extract (EE) of Pao pereira in classic murine models of inflammation and pain. The EE and PPAC fraction, both at a dose of 30 mg/kg, significantly reduced mice abdominal constriction induced by acetic acid by 34.8% and 47.5%, respectively. In the formalin test, EE (30 mg/kg) and PPAC fraction (30 and 60 mg/kg) inhibited only the second phase, by 82.8%, 84.9% and 100%, respectively. Compared with indomethacin, similar doses of EE or PPAC fraction were approximately twice as effective in causing antinociception. PPAC fraction was not effective in the hot plate test but reduced the inflammatory response at the second (50.6%) and third (57.8%) hours of rat paw edema induced by carrageenan. Antihyperalgesic activity was observed within 30 min with a peak at 2 h (60.1%). These results demonstrate that compounds in PPAC fraction have anti-inflammatory and antinociceptive activity by a mechanism apparently unrelated to the opioid system. Regardless of similar responses to indomethacin, the effects of PPAC fraction are mainly attributed to acetylcholine actions.

Triterpenes involved in the anti-inflammatory effect of ethanolic extract of Pterodon emarginatus Vogel stem bark

2011 ◽  
Vol 66 (1) ◽  
pp. 202-207 ◽  
Author(s):  
Weuller F. de Moraes ◽  
Pablinny Moreira Galdino ◽  
Marcus Vinícius M. Nascimento ◽  
Frederico Argollo Vanderlinde ◽  
Maria Teresa F. Bara ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Stem Bark ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Anti-inflammatory effect of the ethanolic extract from Bowdichia virgilioides H.B.K stem bark

2010 ◽  
Vol 82 (3) ◽  
pp. 609-616 ◽  
Author(s):  
Wander M. Barros ◽  
Vietla S.N. Rao ◽  
Regilane M. Silva ◽  
Joaquim C.S. Lima ◽  
Domingos T.O. Martins
Keyword(s):  
Acetic Acid ◽  
Antinociceptive Effect ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Significant Inhibition ◽  
Second Phase ◽  
Traditional Use ◽  
Inflammatory Conditions ◽  
Folk Remedy ◽  
Anti Inflammatory

Bowdichia virgilioides H.B.K stem bark (Fabaceae), locally known as "sucupira-preta", is a reputed folk-remedy to treat some inflammatory disorders. To validate its traditional claim, the ethanolic extract from B. virgilioides was evaluated in several animal models of inflammation and nociception. The extract at oral doses of 100 to 1000 mg/kg body weight caused a significant inhibition of carrageenan-induced hind paw oedema, suppression of exudate volume and leukocyte immigration in rat pleurisy induced by carrageenan, and reduction of granuloma weights in the model of subcutaneous granulomas promoted by cotton pellets. In addition, the plant extract significantly inhibited the vascular permeability increase induced by intraperitoneal acetic acid. It also showed marked antinociceptive effect in acetic acid-induced writhing test and in the second phase of formalin test in mice. These findings evidence the anti-inflammatory potential of Bowdichia virgilioides bark and supports its traditional use in inflammatory conditions.

scholarly journals Analgesic, anti-inflammatory and antipyretic activities of ethanolic extract of stem bark of Anogeissus latifolia Roxb

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Vikas Chandra Sharma ◽  
Atul Kaushik ◽  
Yadu Nandan Dey ◽  
Bhavana Srivastava ◽  
Manish Wanjari ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Stem Bark ◽  
Anti Inflammatory

Antibacterial, Antioxidant and Anti-Inflammatory Potential of the Different Extracts of Holoptelia Integrifolia

2019 ◽  
Vol 9 (2) ◽  
pp. 5234-5240
Author(s):  
Dr.T.Mohammad Munawar ◽  
◽  
Dr.D.Muralidhara Rao ◽  
Dr. P. Subramanyam ◽  
◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Stem Bark ◽  
Inflammatory Activity ◽  
Diffusion Method ◽  
Albino Rats ◽  
Nitric Oxide Radical ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

Medicinal plants are play significant impact in the personal medicine for most of the people all over the world as an alternative live saving medicines and most of their medicinal properties are well known for anticancer activity. The different extracts of Holoptelea integrifolia (H.integrifolia) leaves, stem bark and fruits were studied as a potent natural source of antimicrobial, antioxidant and wound healing potential. This work was carried out to evaluate antimicrobial, antioxidant and anti-inflammatory activity of different extracts of H.integrifolia. The antimicrobial activity of the H.integrifolia ethanolic extract was studied against five fungal and bacterial strains by utilizing the agar well diffusion method and MIC. Among several strain, the ethanolic extract of fruit has shown higher antimicrobial inhibition zone as 9.25-16 mm compare to other two extracts of stem and leaves as 10- 13.25 mm and 6-10.2 mm respectively. The antioxidant activities for different extract were also determined by DPPH free radical assay, Hydroxyl Radical Scavenging and Nitric Oxide Radical Scavenging Activity method. The anti-inflammatory activity also estimated basedon formalin induced paw edema method on Wistar albino rats. The different extracts of leaves, stem bark and fruit parts of Holoptelea integrifolia were estimated for in vivo anti-inflammatory activity against the animal model of female Wistar albino rats. The results of anti-inflammatory activity revealed that the Ethanol extracts showed vital and dose-dependent anti-inflammatory effects. Our findings revealed that aerial parts of H.integrifolia contais potential antimicrobial, antioxidant and anti-inflammatory compounds, which expose the medicinal potential of the selected plant could be a significant drug candidates against microbial, oxidative and inflammation-related pathological processes as a future alternative medicine.

Sign in / Sign up

Export Citation Format

Share Document