scholarly journals The Influence of Glycemic Control on Heart Rate Variability and Blood Pressure in Adult Patients with the Type 1 Diabetes

2018 ◽  
Vol 25 (1) ◽  
pp. 67-75
Author(s):  
Nataliia Pertseva ◽  
Iryna Tyshchenko ◽  
Kateryna Moshenets
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Diastolic Pressure ◽  
Low Frequency ◽  
Rr Intervals ◽  
Area Index

AbstractBackground and aims: to identify heart rate variability (HRV) and blood pressure (BP) in patients with type 1 diabetes depending on the duration of disease and glycemic control.Materials and methods: 43 patients were examined. All patients were divided into 2 groups according to the level of НвА1с: group 1 (n=21) with НвА1с ≤ 7.5% and group 2 (n=22) with НвА1с > of 7.5%. All patients underwent daily monitoring of electrocardiogram Holter and ambulatory BP monitoring within 24 hours in parallel with long term monitoring of blood glucose.Results: Hyppoglycemia is characterized by significant decrease root mean square difference between adjacent RR intervals (RMSSD) (r = −0.531; p = 0.003) and number of consecutive RR intervals, the difference between them is more than 50 ms expressed as a percentage of total number of RR-intervals (pNN50%) (r = the −0.503; p = 0.005) and increase of Low Frequency/High Frequency Ratio (LF/HF) (r = 0552; p = 0.002). Patients with hypoglycemia had significantly higher daily diastolic pressure area index (DPAI24) (p = 0.016), and daily diastolic pressure time index DPTI24 (p = 0.025).Conclusion: our findings demonstrate the need to reduce the frequency of hypoglycemia episodes in patients with T1DM.

scholarly journals Impact of Glycemic Control on Heart Rate Variability in Youth with Type 1 Diabetes: The SEARCH CVD Study

2013 ◽  
Vol 15 (12) ◽  
pp. 977-983 ◽  
Author(s):  
Mamta Jaiswal ◽  
Tasha E. Fingerlin ◽  
Elaine M. Urbina ◽  
R. Paul Wadwa ◽  
Jennifer W. Talton ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Glycemic Control

scholarly journals Association of cardiac autonomic modulation with physical and clinical features of young people with type 1 diabetes

2016 ◽  
Vol 27 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Anne K. F. Silva ◽  
Diego G. D. Christofaro ◽  
Franciele M. Vanderlei ◽  
Marianne P. C. R. Barbosa ◽  
David M. Garner ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Standard Deviation ◽  
Young Patients ◽  
Frequency Component ◽  
Parasympathetic Activity ◽  
High Frequency Component ◽  
Rr Intervals

ObjectiveThe objective of this study was to verify possible associations between heart rate variability indices and physical activity, body composition, and metabolic and cardiovascular parameters in individuals with type 1 diabetes.MethodA total of 39 young patients with type 1 diabetes were included. Body composition, physical activity, cardiovascular parameters, and metabolic parameters were assessed. For the heart rate variability analysis, heart rate was recorded beat-by-beat using a Polar S810i heart rate monitor for 30 minutes, with the volunteers in the supine position; subsequently, the following indices were considered: standard deviation of all normal RR intervals; root-mean square of differences between adjacent normal RR intervals in a time interval; percentage of adjacent RR intervals with a difference of duration >50 ms; high frequency component in milliseconds squared; high frequency component in normalised units; standard deviation of the instantaneous variability beat-to-beat; and standard deviation of the long-term variability. The association between the heart rate variability indices and independent variables was verified through linear regression in unadjusted and adjusted models (considering gender and age). The statistical significance was set at 5% and the confidence interval at 95%.ResultsHigh values of at-rest heart rate were associated with reduced parasympathetic activity and global heart rate variability, and higher values of waist-to-hip ratio were related to lower parasympathetic activity, independent of age or gender.ConclusionFor young patients with type 1 diabetes, increases in at-rest heart rate values are associated with reduced parasympathetic activity and global heart rate variability, whereas higher waist-to-hip ratio values are related to lower parasympathetic activity, both independent of age and gender.

43-LB: Glycemic Control Affects Heart-Rate Variability in Adults with Type 1 Diabetes

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 43-LB
Author(s):  
MINSUN PARK ◽  
MINSEUNG CHU ◽  
YOUNGKWAN SONG ◽  
MERT SEVIL ◽  
ALI CINAR ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Glycemic Control

Poor glycemic control is associated with increased diastolic blood pressure and heart rate in children with Type 1 diabetes

2004 ◽  
Vol 18 (4) ◽  
pp. 220-223 ◽  
Author(s):  
Michael Y Torchinsky ◽  
Ricardo Gomez ◽  
Jay Rao ◽  
Alfonso Vargas ◽  
Donald E Mercante ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Diastolic Blood Pressure ◽  
Poor Glycemic Control

An evaluation of heart rate variability and its modifying factors in children with type 1 diabetes

2013 ◽  
Vol 24 (5) ◽  
pp. 872-879 ◽  
Author(s):  
Senem Özgür ◽  
Özben Ceylan ◽  
Filiz Şenocak ◽  
Utku A. Örün ◽  
Vehbi Doğan ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Low Frequency ◽  
Healthy Control Group ◽  
Control Group ◽  
Haemoglobin A1c ◽  
Very Low Frequency ◽  
Healthy Control

AbstractObjective: To evaluate heart rate variability by Holter monitoring in type 1 diabetic children compared with a healthy control group and determine the factors modifying heart rate variability. Methods: This was designed as a prospective study comparing 28 patients, diagnosed with type 1 diabetes and under follow-up, with 27 healthy control group subjects. Results: The patients were aged 9.9 ± 4.2 years in the diabetic group, including 13 (46.5%) girls and 15 (53.5%) boys. The healthy control group comprised 20 (74%) girls and seven boys (26%) with an average age of 8.6 ± 3.7 years. The search for factors modifying heart rate variability yielded the following correlations: for the time-dependent variables, negative between age and both average and maximal heart rate (r = −0.263 and −0.460, respectively), negative between haemoglobin A1c and percentage of differences between adjacent RR intervals >50 ms, positive between diabetes duration and square root of the mean of the sum of squares of differences between adjacent NN intervals. The average heart rate and percentage of differences between adjacent RR intervals >50 ms was significantly higher in the girls than the boys in all groups. With regard to the frequency-dependent factors affecting heart rate variability, correlations were found between haemoglobin A1c level and both total power and very low frequency (r = −0.751 and −0.644) and between very low frequency and diabetes duration. Conclusion: A reduction in heart rate variability parameters was observed in type 1 diabetes mellitus patients who had a long disease duration or were poorly controlled, as compared with healthy controls.

Abstract 18524: Heart Rate Variability and Cardiovascular Fitness are Lower in Non-hispanic Black versus Non-hispanic White Adolescents With Type 1 Diabetes

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Melissa S Faulkner ◽  
Lauretta Quinn ◽  
Cynthia Fritschi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Heart Association ◽  
Health Care Expenditures ◽  
Cardiovascular Fitness ◽  
Population Projections ◽  
Hispanic White

Type 1 diabetes mellitus (T1D) is growing worldwide with the incidence peaking at puberty. Current population projections indicate that the numbers will nearly triple by 2050 with the prevalence primarily among minority racial/ethnic groups. Future diabetes-related morbidity, mortality and health care expenditures associated with poor cardiovascular (CV) outcomes are of paramount concern. In adolescents with T1D, heart rate variability (HRV) is noted to be lower when compared with healthy control subjects. Current research also supports a level of physical activity for adolescents with T1D that does not meet American Heart Association guidelines of 60 minutes of moderate-to-vigorous intensity per day, leading to decreased levels of physical fitness and elevated HbA1c. T1D Exchange (a large national epidemiological study) found that only 14% of Non-Hispanic Black (NHB) versus 34% Non-Hispanic White (NHW) youth met the American Diabetes Association HbA1c targets of < 7.5%, potentially increasing the odds of poorer outcomes in NHB youth.The hypotheses were that HRV and CV fitness would be lower in NHB versus NHW adolescents with T1D and that those with poorer glycemic control would have lower HRV and CV fitness. Methods: A sample of 96 adolescents with T1D (n = 67 NHW; n = 29 NHB) participated. Using 24-hour holter recordings, both spectral and time domain measures of HRV were obtained. Cardiovascular fitness (V02peak) using a graded exercise test was completed. HbA1c was obtained using the Siemens/Bayer DCA 2000. Findings: There were no significant differences in age (15.4 ± 1.9 vs. 15.0 ± 1.9 years) or duration of diabetes (6.6 ± 3.8 vs. 5.3 ± 3.4 years). Resting diastolic BP, recent and average HbA1c (values averaged over 1 year) were significantly higher (p < 0.05) and measures of HRV and fitness were significantly lower in NHB versus NHW adolescents (p < 0.001). While average HbA1c was associated with lower CV fitness in both NHB and NHW groups (r = -.44 vs. -.25, p < 0.05, respectively), lower measures of HRV were associated with poor glycemic control (HbA1c) only in NHBs (r = -.37 to -.43, p < 0.05). Conclusions: Findings support the importance of early identification of CV health disparities in adolescents with T1D, particularly variation experienced in NHB youth.

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