Serum hypertriglyceridemia as an important risk factor of chronic allograft failure in post-renal transplant patients

2009 ◽  
Vol 22 (1) ◽  
pp. 115-121
Author(s):  
Elżbieta Kimak ◽  
Magdalena Hałabiś
Keyword(s):  
Risk Factor ◽  
Renal Transplant ◽  
Important Risk Factor ◽  
Transplant Patients ◽  
Allograft Failure ◽  
Renal Transplant Patients

scholarly journals Sleep‐Disordered Breathing and 24‐Hour Ambulatory Blood Pressure Monitoring in Renal Transplant Patients: Longitudinal Study

2020 ◽  
Vol 9 (13) ◽  
Author(s):  
Francesca Mallamaci ◽  
Rocco Tripepi ◽  
Graziella D'Arrigo ◽  
Vincenzo Panuccio ◽  
Giovanna Parlongo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Renal Transplant ◽  
Ambulatory Blood Pressure ◽  
Sleep Disordered Breathing ◽  
Interquartile Range ◽  
Apnea Hypopnea Index ◽  
Transplant Patients ◽  
Renal Transplant Patients

Background Sleep‐disordered breathing ( SDB ) is considered a strong risk factor for hypertension in the general population. This disturbance is common in end‐stage kidney disease patients on long‐term hemodialysis and improves early on after renal transplantation. Whether SDB may be a risk factor for hypertension in renal transplant patients is unclear. Methods and Results We investigated the long‐term evolution of simultaneous polysomnographic and 24‐hour ambulatory blood pressure (BP) monitoring recordings in a cohort of 221 renal transplant patients. Overall, 404 paired recordings were made over a median follow‐up of 35 months. A longitudinal data analysis was performed by the mixed linear model. The apnea‐hypopnea index increased from a median baseline value of 1.8 (interquartile range, 0.6–5.0) to a median final value of 3.6 (interquartile range, 1.7–10.4; P =0.009). Repeated categorical measurements of the apnea‐hypopnea index were directly associated with simultaneous 24‐hour, daytime, and nighttime systolic ambulatory BP monitoring (adjusted analyses; P ranging from 0.002–0.01). In a sensitivity analysis restricted to 139 patients with at least 2 visits, 24‐hour, daytime, and nighttime systolic BP significantly increased across visits ( P <0.05) in patients with worsening SDB (n=40), whereas the same BP metrics did not change in patients (n=99) with stable apnea‐hypopnea index. Conclusions In renal transplant patients, worsening SDB associates with a parallel increase in average 24‐hour, daytime, and nighttime systolic BP . These data are compatible with the hypothesis that the link between SDB and hypertension is causal in nature. Clinical trials are, however, needed to definitively test this hypothesis.

Rabbit Antithymocyte Globulin: A Postoperative Risk Factor for Sirolimus-Treated Renal Transplant Patients?

2005 ◽  
Vol 37 (2) ◽  
pp. 822-826 ◽  
Author(s):  
C. Benavides ◽  
K.H. Mahmoud ◽  
R. Knight ◽  
C. Barcenas ◽  
B.D. Kahan ◽  
...  
Keyword(s):  
Risk Factor ◽  
Renal Transplant ◽  
Antithymocyte Globulin ◽  
Transplant Patients ◽  
Postoperative Risk ◽  
Rabbit Antithymocyte Globulin ◽  
Renal Transplant Patients

ANTI-THYMOCYTE RABBIT IMMUNOGLOBULIN: POSTOPERATIVE RISK FACTOR FOR SIROLIMUS TREATED RENAL TRANSPLANT PATIENTS

2004 ◽  
Vol 78 ◽  
pp. 82-83
Author(s):  
C Benavides ◽  
K H. Mahmoud ◽  
R Knight ◽  
C Barcenas ◽  
B Kahan ◽  
...  
Keyword(s):  
Risk Factor ◽  
Renal Transplant ◽  
Transplant Patients ◽  
Rabbit Immunoglobulin ◽  
Postoperative Risk ◽  
Renal Transplant Patients

scholarly journals Colonization of Resistant Microorganisms in Renal Transplants

2020 ◽  
Vol 41 (S1) ◽  
pp. s174-s175
Author(s):  
Monica Taminato ◽  
Dayana Fram ◽  
Thaís Freitas Teles Rezende ◽  
Cibele Grothe ◽  
Antonio Carlos Pignatari ◽  
...  
Keyword(s):  
At Risk ◽  
Risk Factor ◽  
Renal Transplant ◽  
Multidrug Resistant ◽  
Morbidity And Mortality ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Systemic Complications ◽  
Transplant Patients ◽  
Renal Transplant Patients

Background: Kidney transplant recipients are a group of patients at risk for healthcare-related infections. The results of this study make an important clinical contribution and contribute to findings options to decrease the infection-related morbidity and mortality that affects this patient population. Objectives: We evaluated the prevalence of colonization by multidrug-resistant bacteria, Klebsiella pneumoniae carbapenemase (KPC)–producing bacteria, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA) in renal transplant patients; we identified the infection rate, morbidity, and mortality in this population. Methods: Prospective cohort study was conducted at the Kidney and Hypertension Hospital from 2012 to 2015. This project was approved by the Unifesp Research Ethics Committee (no. 1630/11) and an informed consent form was obtained from patients included in the study. Study protocol: Data collection was performed in 2 phases: within the first 24 hours after transplantation and 7 days after transplantation. For all included patients, the following data were collected: identification data, clinical data, and laboratory tests of the first day in the study. All included patients (colonized or not) were followed prospectively for 6 months or until treatment change or death. Results: The study included 200 renal transplant patients in accordance with the inclusion and exclusion criteria. We observed that 76 (38%) patients included in our sample were colonized; 8% S. aureus, 11% Enterococcus, and 19% K. pneumoniae. We verified the presence of concomitant colonization of 1 or more of these pathogens. The most prevalent concomitance identified in our population was E. coli and K. pneumoniae. We identified the presence of diabetes and diabetes associated with hypertension as risk factor for colonization. Thus, patients with more systemic complications may be at risk for colonization by multidrug-resistant bacteria. Another risk factor for colonization was antibiotic use in the 6 months prior to transplantation. Transplant-related outcomes were length of stay after transplantation, delayed graft function (ie, dialysis after the transplantation) and postoperative care in an intensive care unit. At the 6-month follow-up, we identified urinary infection and surgical site infection as risk factors. One death occurred due to stroke in the group of colonized patients, unrelated to infectious causes. Conclusions: These results show fundamental aspects for health professionals for bacterial characterization, transmission, and resistance mechanisms and, mainly, tools for prevention and control of multidrug-resistant bacteria from patients colonized under conservative treatment before the complexity of high-risk procedures begins, such as dialysis and transplantation to reduce morbidity and mortality.Funding: FAPESP São Paulo Research Support FoundationDisclosures: None

Tacrolimus Trough Levels as a Risk Factor for Acute Rejection in Renal Transplant Patients

2016 ◽  
Vol 21 ◽  
pp. 105-114 ◽  
Author(s):  
José Manuel Arreola-Guerra ◽  
Marcos Serrano ◽  
Luis E. Morales-Buenrostro ◽  
Mario Vilatobá ◽  
Josefina Alberú
Keyword(s):  
Risk Factor ◽  
Renal Transplant ◽  
Acute Rejection ◽  
Transplant Patients ◽  
Renal Transplant Patients ◽  
Trough Levels

Pulse pressure is an independent risk factor of cardiovascular disease in renal transplant patients

2003 ◽  
Vol 35 (5) ◽  
pp. 1730-1731 ◽  
Author(s):  
G Fernández-Fresnedo ◽  
R Escallada ◽  
E Rodrigo ◽  
A.L.M de Francisco ◽  
S Sanz de Castro ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Risk Factor ◽  
Renal Transplant ◽  
Pulse Pressure ◽  
Independent Risk Factor ◽  
Transplant Patients ◽  
Renal Transplant Patients

Posttransplant diabetes is a cardiovascular risk factor in renal transplant patients

2003 ◽  
Vol 35 (2) ◽  
pp. 700 ◽  
Author(s):  
G Fernández-Fresnedo ◽  
R Escallada ◽  
A.L.M de Francisco ◽  
E Rodrigo ◽  
J.A Zubimendi ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cardiovascular Risk ◽  
Renal Transplant ◽  
Cardiovascular Risk Factor ◽  
Transplant Patients ◽  
Renal Transplant Patients

Evidence that oxidative stress is a risk factor for the development of squamous cell carcinoma in renal transplant patients

2007 ◽  
Vol 43 (9) ◽  
pp. 1328-1334 ◽  
Author(s):  
Marcus S. Cooke ◽  
Joy E. Osborne ◽  
Rajinder Singh ◽  
Vilas Mistry ◽  
Peter B. Farmer ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Renal Transplant ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Transplant Patients ◽  
Renal Transplant Patients
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