Two Cases With Cavity Formation Followed by Infection After CT-guided Radiofrequency Ablation for Unresectable Lung Metastases From Colorectal Cancers

138 Background: Radiofrequency ablation (RFA) is increasingly being used for the treatment of intrathoracic malignancies. Although RFA has been found to be promising in the treatment of lung metastases from some types of neoplasms, little is known concerning its clinical significance in the treatment of pulmonary metastasis from esophageal squamous cell carcinoma (ESCC). This retrospective study evaluated the feasibility, safety, and effectiveness of computed tomography-guided RFA for pulmonary metastasis from ESCC. Methods: Of 322 patients with ESCC underwent esophagectomy at Kumamoto University Hospital between January 2007 and May 2015, 23 cases had pulmonary recurrence. Selection criteria for CT-guided RFA for pulmonary metastasis were as follows: (i) there were no distant metastases except for pulmonary lesions, when there were extrapulmonary recurrences that had to be controlled by additional therapies; (ii) there were up to three pulmonary tumors; (iii) the number of pulmonary tumors did not increase over a certain period while receiving pre-RFA chemotherapy; (iv) the metastatic lesions were not adjacent to major pulmonary vessels, major bronchi, or the heart. 17 patients who underwent CT-guided RFA for metachronous pulmonary metastasis from ESCC were included in this study. Results: Correct placement of the ablation device into the target tumor proved to be feasible in all tumors (100%). The mean visual analog scale score, with values that ranged from 0 (no pain) to 10 (worst pain possible), was 1. This suggested that this procedure was well tolerated. No procedure-related deaths occurred. A pneumothorax needing drainage was a major complication in two patients. 6 patients died of recurrent disease. The predicted 1- and 2-year overall survival rates after lung RFA were 78.8% and 46.7%, respectively. Conclusions: Percutaneous computed tomography-guided RFA yielded relatively high levels of local control in patients with pulmonary metastases from ESCC and was associated with an acceptable level of complications. It was concluded that a prospective study will be necessary to evaluate the effectiveness of a combination of systemic therapy and RFA for ESCC lung metastases.

Download Full-text

CT-guided percutaneous radiofrequency ablation for lung metastases from colorectal cancer

International Journal of Clinical Oncology ◽

10.1007/s10147-018-1357-5 ◽

2018 ◽

Vol 24 (3) ◽

pp. 288-295 ◽

Cited By ~ 2

Author(s):

Yukiharu Hiyoshi ◽

Yuji Miyamoto ◽

Yuki Kiyozumi ◽

Hiroshi Sawayama ◽

Kojiro Eto ◽

...

Keyword(s):

Colorectal Cancer ◽

Radiofrequency Ablation ◽

Lung Metastases ◽

Percutaneous Radiofrequency Ablation ◽

Ct Guided

Download Full-text

Long-term Survival Following Radiofrequency Ablation of Lung Metastases in an Elderly Patient With Calcaneal Osteosarcoma: a Case Report and Review of the Literature

10.21203/rs.3.rs-285306/v1 ◽

2021 ◽

Author(s):

Hiroyuki Futani ◽

Haruyuki Takaki ◽

Tatsuo Sawai ◽

Junichi Taniguchi ◽

Yasukazu Kako ◽

...

Keyword(s):

Elderly Patient ◽

Radiofrequency Ablation ◽

Elderly Patients ◽

Lung Metastases ◽

Invasive Technique ◽

Term Survival ◽

Ct Guided ◽

Initial Surgery ◽

Alive With Disease ◽

High Grade Osteosarcoma

Abstract Background: Lung metastases are the primary cause of death from osteosarcomas. Complete resection of lung metastases can prolong the survival. However, complete surgical resection in elderly patients is often difficult due to high risk of peri-operative complications. Radiofrequency ablation (RFA) is a minimally invasive technique to destroy tumor nodules using heat. Here, we present an elderly patient with osteosarcoma in calcaneus a scapular osteochondroma, who metachoronusly developed multiple lung metastases. Subsequently, he has been surviving a relatively long period by the use of percutaneous computed tomography (CT)-guided lung RFA against his lung metastases.Case presentation: A 74-year-old male presented with 1-year history of heel pain. Imaging analysis demonstrated a mixture of osteolytic and osteosclerotic lesions in the calcaneus with extraskeletal lesions. The histology of the biopsy specimen showed osteoid matrix with malignant spindle cells, which was diagnosed as a conventional high-grade osteosarcoma. Below-knee amputation was performed. However, 6 lung metastases were found in both lungs 1 year after surgery. During 4.5 years from the initial percutaneous CT-guided lung RFA, 18 lung metastases were treated in 8 procedures. Lung RFA was performed under moderate sedation and local anesthesia. The most frequent complication was pneumothoraxes in 3 procedures followed by pleuritis with pneumothorax in 1 procedure. Chest tube drainage was required in 2 of 8 (25%) lung RF procedures. Mean duration of hospital stay for lung RFA was 5.3 ± 2.1 days (range, 3-10 days). The patient has been alive with disease for 5.5 years after initial surgery. Conclusion: Our experience indicates that lung RFA is effective for elderly patients with lung metastases of osteosarcoma without serious complications.

Download Full-text

Myoglobinemia After CT-Guided Radiofrequency Ablation of a Hepatic Metastasis

American Journal of Roentgenology ◽

10.2214/ajr.178.2.1780359 ◽

2002 ◽

Vol 178 (2) ◽

pp. 359-361 ◽

Cited By ~ 14

Author(s):

Sridhar Shankar ◽

Kemal Tuncali ◽

Eric vanSonnenberg ◽

Julian L. Seifter ◽

Stuart G. Silverman

Keyword(s):

Radiofrequency Ablation ◽

Hepatic Metastasis ◽

Ct Guided

Download Full-text

Novel strategy to treat lung metastases: Hybrid therapy involving surgery and radiofrequency ablation

Thoracic Cancer ◽

10.1111/1759-7714.14041 ◽

2021 ◽

Author(s):

Takaaki Hasegawa ◽

Hiroaki Kuroda ◽

Noriaki Sakakura ◽

Yozo Sato ◽

Shohei Chatani ◽

...

Keyword(s):

Radiofrequency Ablation ◽

Lung Metastases ◽

Hybrid Therapy ◽

Novel Strategy

Download Full-text

A CT-free protocol to treat osteoid osteoma of the hip region in childhood and adolescence by percutaneous drilling and by hip arthroscopy

Hip International ◽

10.1177/1120700021996269 ◽

2021 ◽

pp. 112070002199626

Author(s):

Oliver Eberhardt ◽

Thekla von Kalle ◽

Rebecca Matthis ◽

Richard Doepner ◽

Thomas Wirth ◽

...

Keyword(s):

Radiofrequency Ablation ◽

Minimally Invasive ◽

Hip Joint ◽

Hip Arthroscopy ◽

Standard Form ◽

Childhood And Adolescence ◽

Ct Guided ◽

Contrast Enhanced ◽

Mri Guided ◽

Mri Diagnostics

Introduction: It is often difficult to clinically and radiologically diagnose intra-articular osteoid osteomas and osteoid osteomas of the hip joint. Treatment can also be difficult due to complex locational relationships. CT-guided radiofrequency ablation is currently the standard form of treatment. In this paper we report on a minimally-invasive concept for treating osteoid osteomas near the hip joint in children and adolescents which does not involve using computed tomography. Material and method: 10 patients with an average age of 12.1 years underwent treatment for osteoid osteomas in the hip joint region. The diagnosis was made using a contrast-enhanced MRI. The osteoid osteomas were marked percutaneously using x-ray and MRI guidance. MRI-guided drilling/curettage was performed in 4 cases and arthroscopic resection in 6 cases. Results: All lesions were successfully treated using the MRI-guided method. All patients were free of pain after the treatment. There was no instance of recurrence during the follow-up period, which averaged 10 months. The effective dose for marking the lesion was between 0.0186 mSv and 0.342 mSV (mean 0.084 mSV). Conclusions: Our MRI diagnostics protocol, the MRI-guided drilling and the minimally invasive hip arthroscopy represent an alternative to CT-guided radiofrequency ablation in the treatment of osteoid osteomas. Radiation exposure can thereby be significantly reduced. Hip arthroscopy can also be used to treat secondary pathologies such as femoroacetabular impingement.

Download Full-text