Prevalence of Helicobacter pylori infection in adult patients with dyspeptic symptoms in Abdi Waluyo Hospital Jakarta from January 2017 to December 2019

Background: Helicobacter pylori infection is a global public health problem and may be present in more than half of the world’s population Prevalence in developing country higher compared to developed country. However, in Indonesia prevalence of Helicobacter pylori infection is still low compare to other Asian countries. This study aims to determine the prevalence of Helicobacter pylori infection in Abdi Waluyo Hospital Jakarta from January 2017 to December 2019.Method: In this cross sectional study, a total of 772 adult patients were tested using Urea Breath Test-14C for detection of isotopic carbon produced by Helicobacter pylori ability to broke down urea.Results: Prevalence of Helicobacter pylori infection in Abdi Waluyo hospital between January 2017 – December 2019 was 20.98% with endoscopic findings as follows: 17.48% with gastritis, 3.24% with gastric ulcers , 0.26% with gastric cancerConclusion: Increase prevalence of Helicobacter pylori infection every year in Abdi Waluyo hospital. It is suggested to perfom Urea Breath Test for adult patients with dyspeptic symptoms to screened Helicobacter pylori infection.

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DIAGNOSTIC ACCURACY OF UREA BREATH TEST FOR HELICOBACTER PYLORI INFECTION IN CHILDREN WITH DYSPEPSIA IN COMPARISON TO HISTOPATHOLOGY

Arquivos de Gastroenterologia ◽

10.1590/s0004-28032016000200011 ◽

2016 ◽

Vol 53 (2) ◽

pp. 108-112 ◽

Cited By ~ 4

Author(s):

Naser HONAR ◽

Alireza MINAZADEH ◽

Nader SHAKIBAZAD ◽

Mahmood HAGHIGHAT ◽

Forough SAKI ◽

...

Keyword(s):

Helicobacter Pylori ◽

Carbon Isotope ◽

Sensitivity And Specificity ◽

Breath Test ◽

Close Association ◽

Urea Breath Test ◽

Helicobacter Pylori Infection ◽

Cross Sectional ◽

Predictive Values ◽

H Pylori

ABSTRACT Background - Helicobacter pylori infection is the gram negative bacillus with the close association with chronic antral gastritis. Objective - In this study, we evaluate the accuracy of urea breath test (UBT) with carbon isotope 13 in comparison with histopathology of gastric antrum for detection of H. pylori infection in children with dyspepsia. Methods - This cross-sectional study was performed at specialized laboratory of Shiraz Gastroenterohepatology Research Center and Nemazee Hospital, Iran, during a 12-months period. This study investigated the sensitivity, specificity, and positive and negative predictive values of UBT in comparison with biopsy-based tests. We included a consecutive selection of 60 children who fulfilled Rome III criteria for dyspepsia. All children were referred for performing UBT with carbon isotope 13 (C13) as well as endoscopy. Biopsies were taken from antrum of stomach and duodenum. The pathologic diagnosis was considered as the standard test. Results - The mean age of the participants was 10.1±2.6 (range 7-17 years). From our total 60 patients, 28 (46.7%) had positive UBT results and 32 (53.3%) had negative UBT results. Pathologic report of 16 (57.1%) out of 28 patients who had positive UBT were positive for H. pylori and 12 (42.9%) ones were negative. Sensitivity and specificity of C13-UBT for detection of H. pylori infection were 76.2% and 69.2% respectively. Conclusion - Sensitivity and specificity of C13-UBT for detection of H. pylori infection were 76.2% and 69.2% respectively. Another multicenter study from our country is recommended.

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Sex differences in urea breath test results for the diagnosis of Helicobacter pylori infection: a large cross-sectional study

Biology of Sex Differences ◽

10.1186/s13293-017-0161-7 ◽

2018 ◽

Vol 9 (1) ◽

Cited By ~ 9

Author(s):

Ido Eisdorfer ◽

Varda Shalev ◽

Sophy Goren ◽

Gabriel Chodick ◽

Khitam Muhsen

Keyword(s):

Helicobacter Pylori ◽

Sex Differences ◽

Breath Test ◽

Cross Sectional Study ◽

Urea Breath Test ◽

Helicobacter Pylori Infection ◽

Test Results ◽

Sectional Study ◽

Cross Sectional

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Helicobacter pylori Infection in Children with Phenylketonuria Does Not Depend on Metabolic Control and Is Not More Frequent Than in Healthy Subjects—A Cross-Sectional Study

Children ◽

10.3390/children8080713 ◽

2021 ◽

Vol 8 (8) ◽

pp. 713

Author(s):

Marek Walkowiak ◽

Łukasz Kałużny ◽

Renata Mozrzymas ◽

Małgorzata Jamka ◽

Bożena Mikołuć ◽

...

Keyword(s):

Helicobacter Pylori ◽

Metabolic Control ◽

Healthy Subjects ◽

Breath Test ◽

Cross Sectional Study ◽

Urea Breath Test ◽

Helicobacter Pylori Infection ◽

Cross Sectional ◽

Forward Stepwise ◽

13C Urea Breath Test

In a small preliminary study, phenylketonuria and poor metabolic control were suggested as risk factors for Helicobacter pylori infection in children as detected with an antigen stool test. We aimed to determine Helicobacter pylori prevalence in an adequately sized group of individuals with phenylketonuria and healthy subjects using the standard gold test (urea breath test). Further, we correlated Helicobacter pylori infection with metabolic control. The study comprised 103 individuals with phenylketonuria and 103 healthy subjects on whom a 13C urea breath test was performed. Blood phenylalanine levels in the preceding year were analysed. The infection rate did not differ between individuals with phenylketonuria and healthy subjects (10.7% vs 15.5%; p = 0.41). The frequency of testing and phenylalanine concentrations of Helicobacter pylori-positive and Helicobacter pylori-negative patients with phenylketonuria did not differ (p = 0.92 and p = 0.54, respectively). No associations were detected for body mass index or metabolic control. Forward stepwise regression models revealed that age (p = 0.0009–0.0016) was the only independent correlate of Helicobacter pylori infection with a relatively low fraction of the variability of the condition being explained (adjR2 = 0.0721–0.0754; model p = 0.020–0.023). In conclusion, Helicobacter pylori infection in phenylketonuria is not more frequent than in the general population. Moreover, it does not depend on metabolic control.

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