scholarly journals Bone Mineral Density of the Tarsals and Metatarsals With Reloading

2008 ◽  
Vol 88 (6) ◽  
pp. 766-779 ◽  
Author(s):  
Mary Kent Hastings ◽  
Judy Gelber ◽  
Paul K Commean ◽  
Fred Prior ◽  
David R Sinacore
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Case Report ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Weight Bearing ◽  
Quantitative Computed Tomography ◽  
Case Description ◽  
Mineral Density ◽  
Lateral Column

Background and PurposeBone mineral density (BMD) decreases rapidly with prolonged non–weight bearing. Maximizing the BMD response to reloading activities after NWB is critical to minimizing fracture risk. Methods for measuring individual tarsal and metatarsal BMD have not been available. This case report describes tarsal and metatarsal BMD with a reloading program, as revealed by quantitative computed tomography (QCT).Case DescriptionA 24-year-old woman was non–weight bearing for 6 weeks after right talocrural arthroscopy. Tarsal and metatarsal BMD were measured with QCT 9 weeks (before reloading) and 32 weeks (after reloading) after surgery. A 26-week progressive reloading program was completed. Change scores were calculated for BMD before reloading and BMD after reloading for the total foot (average of all tarsals and metatarsals), tarsals, metatarsals, bones of the medial column (calcaneus, navicular, cuneiforms 1 and 2, and metatarsal 1), and bones of the lateral column (calcaneus, cuboid, cuneiform 3, and metatarsals 2–5). The percent differences in BMD between the involved side and the uninvolved side were calculated.OutcomesBefore reloading, BMD of the involved total foot was 9% lower than that on the uninvolved side. After reloading, BMD increased 22% and 21% for the total foot, 16% and 14% for the tarsals, 29% and 30% for the metatarsals, 14% and 15% for the medial column bones, and 28% and 26% for the lateral column bones on the involved and uninvolved sides, respectively. After reloading, BMD of the involved total foot remained 8% lower than that on the uninvolved side.DiscussionThe increase in BMD with reloading was not uniform across all pedal bones; the metatarsals showed a greater increase than the tarsals, and the lateral column bones showed a greater increase than the medial column bones.

scholarly journals The Effect of Quantitative Computed Tomography Acquisition Protocols on Bone Mineral Density Estimation

2015 ◽  
Vol 137 (11) ◽  
Author(s):  
Hugo Giambini ◽  
Dan Dragomir-Daescu ◽  
Paul M. Huddleston ◽  
Jon J. Camp ◽  
Kai-Nan An ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Fracture Risk ◽  
Risk Prediction ◽  
Material Property ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Patient Specific ◽  
Mineral Density ◽  
Fracture Risk Prediction

Osteoporosis is characterized by bony material loss and decreased bone strength leading to a significant increase in fracture risk. Patient-specific quantitative computed tomography (QCT) finite element (FE) models may be used to predict fracture under physiological loading. Material properties for the FE models used to predict fracture are obtained by converting grayscale values from the CT into volumetric bone mineral density (vBMD) using calibration phantoms. If there are any variations arising from the CT acquisition protocol, vBMD estimation and material property assignment could be affected, thus, affecting fracture risk prediction. We hypothesized that material property assignments may be dependent on scanning and postprocessing settings including voltage, current, and reconstruction kernel, thus potentially having an effect in fracture risk prediction. A rabbit femur and a standard calibration phantom were imaged by QCT using different protocols. Cortical and cancellous regions were segmented, their average Hounsfield unit (HU) values obtained and converted to vBMD. Estimated vBMD for the cortical and cancellous regions were affected by voltage and kernel but not by current. Our study demonstrated that there exists a significant variation in the estimated vBMD values obtained with different scanning acquisitions. In addition, the large noise differences observed utilizing different scanning parameters could have an important negative effect on small subregions containing fewer voxels.

scholarly journals Experimental investigation of bone mineral density in Thoroughbreds using quantitative computed tomography

2015 ◽  
Vol 26 (3) ◽  
pp. 81-87 ◽  
Author(s):  
Kazutaka YAMADA ◽  
Fumio SATO ◽  
Tohru HIGUCHI ◽  
Kaori NISHIHARA ◽  
Mitsunori KAYANO ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Experimental Investigation ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Mineral Density

Effect of Rheumatoid Arthritis on Volumetric Bone Mineral Density and Bone Geometry, Assessed by Peripheral Quantitative Computed Tomography in Postmenopausal Women Treated with Bisphosphonates

2012 ◽  
Vol 39 (6) ◽  
pp. 1215-1220 ◽  
Author(s):  
SYMEON TOURNIS ◽  
VASILIOS SAMDANIS ◽  
SAVAS PSARELIS ◽  
CHRYSA LIAKOU ◽  
JULIA ANTONIOU ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Computed Tomography ◽  
Bone Mineral Density ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Bone Geometry ◽  
Peripheral Quantitative Computed Tomography ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

Objective.To investigate the effect of rheumatoid arthritis (RA) on volumetric bone mineral density (vBMD) and bone geometry in postmenopausal women treated with bisphosphonates.Methods.Fifty-three postmenopausal women with RA and 87 control subjects, comparable in terms of age, body mass index, and years since menopause, underwent peripheral quantitative computed tomography (pQCT) of the nondominant tibia.Results.At 4% (trabecular site), trabecular bone mineral content (BMC) and vBMD (p < 0.001) were lower in the RA group, while trabecular area was comparable. At 38% (cortical site), cortical BMC (p < 0.01), area (p < 0.05), and thickness (p < 0.001) were lower in the RA group, whereas vBMD was comparable. Endosteal circumference was higher (p < 0.05), whereas periosteal circumference was comparable, indicating cancellization of cortical bone. In the RA group, muscle area was lower (p < 0.001), while at 14% polar stress strength index was significantly lower (p < 0.01) in patients with RA, indicating impairment of bone mechanical properties.Conclusion.RA is associated with negative effects on both cortical and cancellous bone in postmenopausal women treated with bisphosphonates. Cortical geometric properties are also adversely affected mainly by increased endosteal circumference, whereas trabecular geometric properties are generally preserved.

Bone Mineral Density of Cervical Spine Vertebrae Using Quantitative Computed Tomography

2004 ◽  
Author(s):  
Narayan Yoganandan ◽  
Frank A. Pintar ◽  
Recai Aktay ◽  
Glenn Paskoff ◽  
Barry S. Shender
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Cervical Spine ◽  
Bone Mineral ◽  
Cervical Vertebrae ◽  
Quantitative Computed Tomography ◽  
Mineral Density ◽  
Healthy Human ◽  
Computed Tomography Scanning ◽  
And Gender

While numerous studies exist quantifying the bone mineral content of the human lumber vertebrae, such information is not available for the cervical spine. This study determined the bone mineral densities of cervical vertebrae. Adult healthy human volunteers, ages ranging from 18 to 40 years, underwent quantitative computed tomography scanning of the neck. BMD data were divided according to subject weight (above and below 50th percentile, termed low and heavy mass) and gender. Low-mass subjects did not consistently have higher bone mineral density at all levels of the cervical column. Bone mineral were higher (259 ± 6 mg/cc) for females than males (247 ± 8 mg/cc); for the entire ensemble the mean density was 253 ± 9 mg/cc. Altered strength of cervical vertebrae coupled with the increased mobility of the disc at the inferior levels of the neck may explain regional biomechanical differences and subsequent physiologic effects secondary to aging. This study quantifies BMD of the human neck vertebrae and offers explanations to the biomechanical behaviors of the human cervical spine.

Sign in / Sign up

Export Citation Format

Share Document