scholarly journals Cultural dermatoses: A review

2021 ◽  
Vol 0 ◽  
pp. 1-7
Author(s):  
Reshma Kunhi Kannan
Keyword(s):  
Child Abuse ◽  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Correct Diagnosis ◽  
Religious Practices ◽  
Cultural Perception ◽  
Acupuncture And Moxibustion ◽  
And Migration ◽  
Allergic Contact ◽  
The Impact

The impact of globalization and migration is reflected in cultural dermatoses which in earlier times were localized to specific regions. Therapeutic, cosmetic, and religious practices can lead to dermatoses. Therapeutic practices such as cupping, coining, acupuncture, and moxibustion may cause purpura and ecchymoses which are sometimes mistaken for child abuse. Cultural perception of beauty is often the motivation behind practices such as threading, use of bleaching agents, henna, bindi, and hair oils, which, in turn, can cause irritant and allergic contact dermatitis as well as a host of other dermatoses. Prayer nodules and turban dermatoses may manifest as outcomes of culture specific religious practices. A knowledge of these conditions can help the dermatologist to offer a correct diagnosis and treatment.

Nickel Allergy of the Skin and Beyond

2020 ◽  
Vol 20 (7) ◽  
pp. 1003-1009
Author(s):  
Malena Gergovska ◽  
Razvigor Darlenski ◽  
Jana Kazandjieva
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Contact Allergy ◽  
Correct Diagnosis ◽  
Large Population ◽  
Modern World ◽  
Nickel Allergy ◽  
Positive Skin ◽  
Diagnostic Potential ◽  
Allergic Contact

Background: Hypersensitization to nickel is one of the most common contact allergies in the modern world and it is considered to be a major cause of contact dermatitis, especially for hand eczema. Objective: The aim of this paper is to describe many faces of the nickel allergy and to find out different diagnostic, potential strategies for treatment and prevention in hypersensitized patients. A personal clinical experience with practical clinical cases of contact dermatitis to nickel has also been presented. Methods: Electronic databases on this topic was carried out using PubMed-Medline. Results: The literature review identified many articles reporting for nickel contact allergy and pointing the metal as number one allergen in the frequency of positive skin patch test reactions in a large population worldwide. Herein, a summary of the current understanding and evidence on nickel allergy with practical approach and proposed recommendations to the dermatologist, general practitioner, and the allergist were prepared. Conclusions: The prevalence of nickel allergy represents an important socio-economical and health issue. Metal is one of the most common sensitizing agents worldwide. The morbidity due to this metal represents the allergic contact dermatitis and it is constantly growing in many countries. There are also cases of systemic allergic contact dermatitis, where they could be easily misdiagnosed as adverse drug reactions, which lead to delay of the correct diagnosis and inappropriate treatment.

scholarly journals Contact dermatitis as a result of the aggression of the environment. How to treat?

2015 ◽  
Vol 12 (5) ◽  
pp. 76-81
Author(s):  
Y K Kuznetsova
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Mometasone Furoate ◽  
Scale Assessment ◽  
Allergic Contact ◽  
The Impact ◽  
Global Data ◽  
Over Time

Background. To estimate the efficiency, tolerability of mometasone furoate cream «Momat» in treating of allergic contact dermatitis. Methods. There were involved 42 patients suffering from allergic contact dermatitis. The patients were applying mometasone furoate cream 1 time per day during 2-3 weeks according to the submitted written instructions. Index SCOREPI (SCOre de Reparation de l’EPIderme) and 5D-scale assessment of pruritus (index shows changes in the sensation of pruritus over time) have been used as the methods of estimation of the efficiency of therapy. Results. In 98% of participants compliance with prescribed therapy was achieved. This corresponds to a global data about the impact of various factors on adherence of patients suffering from allegic contact dermatitis. Researchers evaluated the tolerability of «Momat» cream as «good» in the majority of cases and «very good» or «excellent» in 93% of patients. Conclusion. According to the study it can be concluded that application of «Momat» cream once a day during 2 weeks is effective and safe.

scholarly journals NLRP3 Inflammasome and Allergic Contact Dermatitis: A Connection to Demystify

Pharmaceutics ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 867
Author(s):  
Ana Isabel Sebastião ◽  
Isabel Ferreira ◽  
Gonçalo Brites ◽  
Ana Silva ◽  
Bruno Miguel Neves ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Nlrp3 Inflammasome ◽  
Molecular Mechanisms ◽  
Alternative Methods ◽  
Inflammasome Activation ◽  
Pyrin Domain ◽  
And Migration ◽  
Novel Therapeutic Strategies ◽  
Allergic Contact

Allergic contact dermatitis is a common occupational disease that manifests as a cell-mediated hypersensitivity reaction following skin exposure to small reactive chemicals termed haptens. Haptens penetrate the stratum corneum and covalently modify proteins in the epidermis, inducing intracellular stress, which further leads to the release of damage-associated molecular patterns (DAMPs), such as uric acid, reactive oxygen species, hyaluronic acid fragments and extracellular adenosine triphosphate (ATP). These DAMPs are recognized by pattern recognition receptors (PRRs) in innate immune cells, namely dendritic cells (DCs), leading to their maturation and migration to the draining lymph nodes where they activate naïve T lymphocytes. Among all PRRs, several studies emphasize the role of NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome on the allergic contact dermatitis (ACD) sensitization phase. However, skin allergens—danger signals—NLRP3 inflammasome axis is yet to be completely elucidated. Therefore, in this review, we sought to discuss the molecular mechanisms underlying DAMPs release and NLRP3 inflammasome activation triggered by skin allergens. The elucidation of these key events might help to identify novel therapeutic strategies for ACD, as well as the development of nonanimal alternative methods for the identification and potency categorization of skin sensitizers.

scholarly journals Occupational Allergic Contact Dermatitis Caused by Epoxy Resin in the Centre of Portugal

2019 ◽  
Vol 77 (3) ◽  
pp. 221-225
Author(s):  
Mariana Ferreira Bastos ◽  
Ricardo Batista ◽  
Diogo Laertes ◽  
Joana Calvão ◽  
Margarida Gonçalo
Keyword(s):  
Contact Dermatitis ◽  
Epoxy Resin ◽  
Allergic Contact Dermatitis ◽  
Patch Test ◽  
Epoxy Resins ◽  
Occupational Exposures ◽  
Positive Patch Test ◽  
Test Reactions ◽  
Allergic Contact ◽  
The Impact

Introduction. Occupational Allergic Contact Dermatitis is a very common occupational disease and epoxy resins are among its main causes. The aim of this study was to characterize patients with positive patch test reactions to epoxy resin detected in the Coimbra Hospital and University Center between 2012 and 2018 and compare with the results of patients patch tested between 1999 and 2008 at the same Institution. Method and Materials.  Within aretrospective analysis of the files of patients with positive patch test reactions (1+ or more intense) to epoxy resin of bisfenol A tested at 1% pet. within the Baseline Series between 2012 and 2018, we characterized demographic and clinical data of reactive patients, evaluated the relevance of the reaction, sources of exposure to epoxy resin with particular attention to occupational exposures, other positive reactions and the impact of the results of the tests in the work conditions of these patients. Lastly, we compared these results with a previous study performed in the same Hospital between 1999 and 2008. Results. Among 2363 patch tested patients during the study period we found 23 patients (0.97%), 17 males and 6 females, who developed contact allergy to epoxy resins. In 22 cases we identified a relevant occupational exposure: 9 from construction industry; 9 workers from wind-mill turbines factory for Eolic energy; 2 from fiberglass factories; 1 from a chemical factory and 1 from a Wastewater Treatment Plant. In 1 patient (a teacher) no relevance was found. Of these 22 workers, 9 (39.1%) had both hand and airborne lesions, while 8 (34.8%) had lesions exclusively on the hands and 5 (21.7%) had predominately airborne dermatitis. Four of the 23 (17.4%) reacted exclusively to the epoxy resin, and 11 of 18 (61.1%) also reacted to 0.25% hexanediol diglycidyl ether. Avoidance resulted in a significant improvement of symptoms. Compared to the previous period (1999-2008), there are no significative changes apart from a slight increase in the frequency of the allergic reactions to epoxy resins and its main source of exposure. Conclusions. The prevalence of allergic contact dermatitis to epoxy resin has slightly increased in this Portuguese Center mostly due to workers from wind-mill turbines factory for Eolic energy, a recent industry implanted in this region. This allergen still causes almost exclusively occupational dermatitis, either hand, airborne, or both.

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