scholarly journals Magnetic resonance imaging features of “Proximal” hirayama disease: Case report and literature review

2021 ◽  
Vol 12 ◽  
pp. 622
Author(s):  
Ramakrishna Narra ◽  
Suseel Kumar Kamaraju

Background: Proximal “Hirayama” disease (PHD) is characterized by proximal upper extremity atrophy. It is a rare variant of Hirayama disease (HD) which involves the proximal upper limb. Recognition of PHD’s unique magnetic resonance (MR) findings is critical as the treatment options differ versus classical HD. Case Description: A 17-year-old male presented with gradual progressive upper extremity weakness and atrophy. On MR, PHD was demonstrated by C4-C5 kyphosis with a posterior epidural soft-tissue mass compressing the C4-C5 cord resulting in gliosis. As the patient declined surgery, he was followed for 1 year with a cervical collar during which time his deficit stabilized. Conclusion: PHD, characterized by proximal upper extremity weakness and atrophy, has characteristic MR findings of kyphosis associated with cord compression and ischemia/gliosis. Select patients as the one we described who decline surgery may stabilize radiographically and clinically with the protracted utilization of a cervical collar.

2004 ◽  
Vol 94 (6) ◽  
pp. 587-589 ◽  
Author(s):  
Tuba Karagülle Kendi ◽  
Aziz Erakar ◽  
Olcay Oktay ◽  
H. Yusuf Yildiz ◽  
Yener Saglik

Accessory soleus muscle is an uncommon anatomical variant that may present as a soft-tissue mass in the posteromedial region of the ankle. It is congenital in origin but usually presents in the second or third decade of life. Although it is a rare entity, accessory soleus muscle should be included in the differential diagnosis of soft-tissue swelling of the ankle. Awareness of the clinical presentation and specific findings of computed tomography, magnetic resonance imaging, and electromyography help with diagnosis without surgical exploration. We describe a 30-year-old patient with accessory soleus muscle. Magnetic resonance imaging features of the case are described, and the literature is briefly reviewed. (J Am Podiatr Med Assoc 94(6): 587–589, 2004)


2019 ◽  
Vol 11 (1) ◽  
pp. 106-111 ◽  
Author(s):  
Akira Yokote ◽  
Kousuke Fukuhara ◽  
Jun Tsugawa ◽  
Yoshio Tsuboi

Hirayama disease is a distinct type of cervical myelopathy characterized by juvenile onset of unilateral muscular atrophy of a distal upper extremity. We report herein a case with Hirayama disease-like juvenile muscular atrophy involving proximal muscles in the upper extremities. In this case, in the flexion position of the neck, cervical magnetic resonance imaging revealed that the spinal cord was compressed by expansion of the posterior extradural space with forward displacement of the dura matter. These neuroimaging results are identical to those of Hirayama disease. However, the involved muscles in this case were the proximal muscles, unlike Hirayama disease. Five previous cases have displayed this rare subtype of Hirayama disease. The cause of the unique phenotype may be abnormal cervical column alignment, with upper cervical kyphosis producing a higher apex of the vertebral level in a cervical flexion position, resulting in mid-cervical segmental myelopathy.


2010 ◽  
Vol 128 (3) ◽  
pp. 171-173 ◽  
Author(s):  
Adriana Bastos Conforto ◽  
Jovana Gobbi Marchesi Ciríaco ◽  
Fábio Iuji Yamamoto ◽  
Paulo Puglia Júnior ◽  
Claudia da Costa Leite ◽  
...  

CONTEXT: The aim of this paper was to report on the characteristics that aid in establishing the diagnosis of basilar artery occlusive disease (BAOD) among patients with hemiparesis and few or minor symptoms of vertebrobasilar disease. CASE REPORT: This report describes two cases in a public university hospital in São Paulo, Brazil. We present clinical and imaging findings from two patients with hemiparesis and severe BAOD, but without clinically relevant carotid artery disease (CAD). One patient presented transient ischemic attacks consisting of spells of right hemiparesis that became progressively more frequent, up to twice a week. The neurological examination revealed slight right hemiparesis and right homonymous hemianopsia. Magnetic resonance imaging (MRI) revealed pontine and occipital infarcts. Magnetic resonance angiography and digital subtraction angiography revealed severe basilar artery stenosis. The other patient presented sudden left-side hemiparesis and hypoesthesia. One year earlier, she had reported sudden onset of vertigo that, at that time, was attributed to peripheral vestibulopathy and was not further investigated. MRI showed a right-side pontine infarct and an old infarct in the right cerebellar hemisphere. Basilar artery occlusion was diagnosed. Both patients presented their symptoms while receiving aspirin, and became asymptomatic after treatment with warfarin. CONCLUSIONS: Misdiagnosing asymptomatic CAD as the cause of symptoms in BAOD can have disastrous consequences, such as unnecessary carotid endarterectomy and exposure to this surgical risk while failing to offer the best available treatment for BAOD. Clinical and imaging features provided important clues for diagnosis in the cases presented.


scholarly journals Effect of dehydroepiandrosterone on ovarian morphology and follicular apoptosis following 4-vinylcyclohexene diepoxide induced premature follicle loss in rats Original Article March 2020 259 Views Aim: Chemical-induced depletion of ovarian follicle pool can lead to premature ovarian failure in rats. In the rat model of 4-vinylcyclohexene diepoxide (VCD)- induced ovarian follicular loss, we tested the hypothesis that Dehydroepiandrosterone (DHEA) could be reversed by short and long-term treatment of follicular loss. Material and Method: All rats were divided into groups for study and treated with dimethylsulfoxide… Additional Info Recieved 13.01.2019 Accepted 13.02.2019 Published Online 19.02.2019 Printed 01.03.2020 DOI 10.4328/ACAM.6163 Author Mehmet Caner Özer, Mehmet Kaya, Ahmet Berkız Turp, Cengiz Bal, Nilüfer Erkasap, Didem Turgut Coşan, Hikmet Hassa Identifier Corresponding Author ORCID ID: https://orcid.org/ 0000-0002-4398-9598 Index Page 104-110 Citations in Google Scholar Google Scholar How to Cite Özer MC, Kaya M, Turp AB, Bal C, Erkasap N, Coşan DT, Hassa H. Effect of dehydroepiandrosterone on ovarian morphology and follicular apoptosis following 4-vinylcyclohexene diepoxide induced premature follicle loss in rats. Ann Clin Anal Med 2020;11(2):104-110 Running Title Dehydroepiandrosterone and premature ovarian loss in a rat model Download attachments: 10.4328ACAM.6163.pdf Read more... Late onset hirayama disease: Characteristic magnetic resonance imaging features hirayana disease Case Report March 2020 346 Views Hirayama Disease is a rare benign lower motor neuron disorder which is primarily affecting young males. It is characterized by the progressive weakness of the distal upper extremities followed by spontaneous stabilization of the symptoms. In this paper, we describe a 58 year- old female patient with a complaint of weakness in the right hand and forearm. Magnetic resonance imaging… Additional Info Recieved 09.01.2019 Accepted 25.01.2019 Published Online 05.02.2019 Printed 01.03.2020 DOI 10.4328/ACAM.6154 Author Kemal Murat Haberal, Aynur Yılmaz Avcı, Mert Bayramoğlu, Ahmet Muhteşem Ağıldere Identifier Corresponding Author ORCID ID: https://orcid.org/0000-0002-8211-4065 Index Page 159-161 Citations in Google Scholar Google Scholar How to Cite Haberal KM, Avcı AY, Bayramoğlu M, Ağıldere AM. Late onset hirayama disease: Characteristic magnetic resonance imaging features hirayana disease. Ann Clin Anal Med 2020;11(2): 159-161 Running Title Hirayama disease Download attachments: 10.4328ACAM.6154.pdf Read more... The relationship between serum vitamin D levels and dry eye syndrome in postmenopausal women

2020 ◽  
Vol 11 (2) ◽  
Author(s):  
Ayşegül Arman

Author(s):  
S.H. Naudé ◽  
D.B. Miller

A 6-year-old, male, Collie-cross was presented with a non-weight bearing right thoracic limb lameness, right m.deltoideus, m.infraspinatus and m.supraspinatus atrophy, and severe neck pain with spasm of the cervical epaxial muscles. MRI revealed complete destruction of the 5th and 6th cervical vertebral bodies with lateral extradural spinal cord compression at the level of the 4th and 5th cervical vertebrae. These lesions were very clearly demonstrated on magnetic resonance images, while only subtle changes were seen on survey radiographs. Post mortem investigation revealed a large heart base chemodectoma with multiple smaller tumours in the cranial mediastinum and a single tumour nodule on the thoracic aorta. The 5th cervical vertebral body had necrotic, haemorrhagic and lytic changes. Histopathology of the heart base tumour, the nodules in the cranial mediastinum and on the thoracic aorta and samples from the 5th cervical vertebra confirmed the presence of a malignant aortic or carotid body tumour originating from the chemoreceptor organs. Diagnostic imaging features and post mortem findings are described. To our knowledge, this is the first report of the magnetic resonance features of a metastatic chemodectoma in a dog.


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