Comparative evaluation of the results of simultaneous and two-stage surgical treatment of patients with advanced proliferative diabetic retinopathy and complicated incipient cataract.

Author(s):  
K.I. Konovalova ◽  
◽  
M.M. Shishkin ◽  

Aim. Undertake a comparative analysis of the results two-stage or simultaneously vitreoretinal surgery with phacoemulsification of PDR patients. Material and methods. 52 cases of surgery treatment of patients with PDR and complicated primary cataract were analyzed. These patients were divided into three groups. In the 1st group patients were subjected to a two–step surgical procedure: vitreoretinal surgery with gas tamponade performed as the 1st step in their treatment; followed by the 2d step, phacoemulsification surgery and the IOL implantation. In the 2d group phacoemulsification performed simultaneously with vitreoretinal surgery: phacoemulsification, IOL implantation, vitreoretinal surgery with gas tamponade. Results. Outcomes of the preliminary studies suggest that it is more viable to perform phacoemulsification surgery sometime later along on PDR patients with complicated primary cataract. Conclusions. This sequence of treatment procedure ensures a more gentle approach to the anatomic structures of the eye during the first stage (vitreoretinal surgery) and contributes to the reduction in the number of intraoperative and postoperative complications. Key words: diabetic retinopathy, cataract, vitreoretinal surgery.

Author(s):  
K.I. Konovalova ◽  
◽  
M.M. Shishkin ◽  

Purpose. To compare and evaluate long-term results of two-stage surgical treatment of patients with advanced proliferative diabetic retinopathy and complicated incipient cataract. Material and methods. 73 patients with advanced proliferative diabetic retinopathy and complicated incipient cataract performed by vitrectomy from 2016 to 2020 were analyzed. In the 1st group patients were subjected to a two-step surgical procedure: vitreoretinal surgery with silicone oil tamponade performed as the 1st step in their treatment; followed by the 2d step, phacoemulsification surgery and silicone oil removal, and the IOL implantation, respectively. In the 2d group phacoemulsification performed simultaneously with vitreoretinal surgery: phacoemulsification, IOL implantation, vitreoretinal surgery with silicone oil tamponade. The second step differed in the removal of silicone oil from the vitreous cavity. Results. Visual functions improved in 88.8% of cases in group 1, and in 51.3% in group 2. Conclusion. Outcomes of the studies suggest that it is more viable to perform phacoemulsification surgery sometime later along with silicone oil removal on PDR patients with complicated primary cataract. This sequence of treatment procedure ensures a more gentle approach to the anatomic structures of the eye during the first stage (vitreoretinal surgery) and contributes to the reduction in the number of intraoperative and postoperative complications. Key words: diabetic retinopathy, cataract, vitreoretinal surgery.


2020 ◽  
Vol 12 (4) ◽  
pp. 43-48
Author(s):  
Karina I. Konovalova ◽  
Mikhail M. Shishkin

The literature review compares the combined (vitreoretinal surgery with silicone tamponade and phacoemulsification of incipient cataract with intraocular lens implantation) and two-stage (phacoemulsification with intraocular lens implantation as a second step, simultaneously with the silicon oil removal, after vitreoretinal surgery) surgical treatment of patients with advanced proliferative diabetic retinopathy and complicated incipient cataract. Modern concepts of treatment tactics of this disease, its efficacy are analyzed. Benefits and drawbacks of each of the discussed surgical treatment methods are specified.


2020 ◽  
Vol 9 (3) ◽  
pp. 369-376
Author(s):  
N. G. Doronin ◽  
S. N. Khoroshkov ◽  
M. V. Naumenko

The aim of the study is the comparative analysis of the long-term results of treatment of extra-articular fractures of the long bones in HIV-infected and non-HIV-infected patients.Material and methods. In the presented study, a comparative analysis of the results of surgical treatment of 90 HIV-infected and 112 HIV-uninfected patients with extra-articular fractures of the long bones of the extremities aged from 23 to 54 years was performed.Results. HIV-infected patients are mainly characterized by non-infectious complications from the postoperative wound (formation of seromas, hematomas, dehiscence of the edges of wounds, delayed healing), aseptic loosening and migration of fixators, and delayed consolidation of fractures. The presence of statistically significant relationships between the factors characterizing the course of HIV infection (stage of the disease, the number of CD4 + lymphocytes, the ratio of CD4/CD8 + lymphocytes, viral load) and the risk of postoperative complications was revealed.Conclusion. Thus, the use of standard algorithms for determining the tactics and method of treatment of extra-articular fractures of the long bones of the extremities in HIV-infected patients leads to a significant number of unsatisfactory treatment results (up to 31.1%). For HIV-infected patients, the most typical complications are postoperative wounds, impaired fracture consolidation processes and aseptic loosening of metal fixators, which can lead to the development of infectious complications without proper attention. Expansion of research in this area with an increase in the number of observed contingents will make it possible to develop a scientifically based scale for predicting the development of possible postoperative complications in this category of patients.


Although the irreversible proliferative complications of diabetes are less visible with anti-vascular endothelial growth factor (anti-VEGF) agents, surgical treatment is still important for these groups of patients; because of the high frequency of diabetes mellitus. The most common indications for vitreoretinal surgery for proliferative diabetic retinopathy are vitreous hemorrhages and tractional retinal detachments. This review summarized the surgical treatment of these two complications.


Author(s):  
K.I. Konovalova ◽  
◽  
M.M. Shishkin ◽  

Purpose. The aim is to estimate the content of pro- and anti-inflammatory cytokines (IL-1β, IL-8, IL-10, MCP-1, ICAM-1, VEGF) in tear of patients with advanced proliferative diabetic retinopathy and complicated primary cataract after phacoemulsification surgery and IOL implantation with vitreoretinal surgery accomplished at once in comparison with vitreoretinal surgery only. Material and methods. 34 cases of surgery treatment of patients with PDR and complicated primary cataract were enrolled. This patients were divided into two groups depending on the treatment tactics. In the 1st group patients were subjected to a two–step surgical procedure: vitreoretinal surgery (VRS) with silicone oil tamponade performed as the 1st step in their treatment; followed by the 2nd step, phacoemulsification surgery and silicone oil removal, and the IOL implantation, respectively. In the 2nd group phacoemulsification performed simultaneously with vitreoretinal surgery: phacoemulsification, IOL implantation, vitreoretinal surgery with silicone oil tamponade. The second step differed in the removal of silicone oil from the vitreous cavity. On the 2nd day after the 1st step surgery and before surgical treatment the tear samples of the patients of both groups have been examined. Results. A concentration of the following cytokines: IL-8, MCP-1, ICAM-1 in the 2nd group was 2,5-5 times higher than in the 1st group. Conclusion. The research revealed that the patients with advanced PDR are accurately determined by the increased concentration of IL-8, MCP-1, ICAM-1 in tear after phacoemulsification surgery and IOL implantation with vitreoretinal surgery accomplished at once in comparison with vitreoretinal surgery only. Keywords: cytokines, diabetic retinopathy, cataract, vitreoretinal surgery.


2011 ◽  
Vol 4 (1) ◽  
pp. 40-44
Author(s):  
Yuri Semenovich Vinnik ◽  
Dmitry Eduardovich Zdzitowiecki

This paper is devoted to the influence of constant transmembrane peritoneal dialysis during the systemic inflammatory response syndrome in patients with general purulent peritonitis (GPP). On the basis of comparative analysis of the results of staged surgical treatment of 67 patients with GPP the clinical efficacy of this method of the abdominal cavity was proved. As a result of constant transmembrane peritoneal dialysis has reduced the absolute risk of postoperative complications in the half-open run by BP at 23,0% and a relative on 27,1%


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