scholarly journals THE CYTOPROTECTIVE EFFECT OF INTERLEUKIN 4 ON FIBROBLASTS COCULTERED WITH THE MONONUCLEARS OF PATIENTS WITH TYPE 2 DIABETES MELLITUS AND THOSE WITH TYPE 2 DIABETES MELLITUS AND CHRONIC FOOT ULCERS IN A 3D CULTURE MODEL

2020 ◽  
Vol 18 (4) ◽  
pp. 410-416
Author(s):  
M. A. Mashkova ◽  
◽  
T. V. Mokhort ◽  
V. A. Goranov ◽  
◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
3D Culture ◽  
Interleukin 4 ◽  
Foot Ulcers ◽  
Cytoprotective Effect ◽  
Culture Model ◽  
3D Culture Model

scholarly journals Diabetic Foot Ulcers and Risk Fall in People with Type 2 Diabetes Mellitus in BLUD RSUD Dr. Ben Mboi Manggarai Regency, NTT

2021 ◽  
Vol 16 (3) ◽  
Author(s):  
Oliva Suyen Ningsih ◽  
Kornelia Romana Iwa ◽  
Maria Getrida Simon ◽  
Kataria Anastasia Sinar
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcers ◽  
P Value ◽  
Diabetic Foot Ulcers ◽  
Risk Of Falling ◽  
Risk Of Falls

The prevalence of diabetes mellitus in Manggarai Regency in 2019 is 535 people and some of them have diabetic foot ulcers. Patients with diabetic foot ulcers had a higher risk of falling than others.This study was to determine the risk factors for diabetic foot ulcers and the risk of falls in patients with type 2 diabetes mellitus. A quantitative study using a cross-sectional study was conducted at BLUD RSUD dr. Ben Mboi  in April-June 2020 (n = 51).The sampling technique used was purposive sampling with a questionnaire of diabetic foot screening and risk stratification form and Morse scale. Logistic regression results showed that there was a significant relationship between claudication (AOR: 8.409, 95% CI 1.664-42.500, p value 0.010), history of previous diabetic foot ulcers (AOR: 5,680, 95% CI 1,151-28,035, p value 0.033) with diabetic foot ulcers. There was a significant relationship between hypertension (AOR: 0.152, 95% CI 0.028-0.834, p value 0.030), diabetic foot ulcers (AOR: 11.392, 95% CI 1.277-101.651, p value 0.029) with the risk of falling for patients with type 2 diabetes mellitus.  Assessment of the risk of diabetic foot ulcers and the risk of falls should be done in patients with diabetes mellitus with or without neuropathy peripheral

scholarly journals Vitamin B12 Deficiency and Foot Ulcers in Type 2 Diabetes Mellitus: A Case–Control Study

2019 ◽  
Vol Volume 12 ◽  
pp. 2589-2596 ◽  
Author(s):  
Mohammed Badedi ◽  
Hussain Darraj ◽  
Abdulrahman Hummadi ◽  
Yahia Solan ◽  
Ibrahim Zakri ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Case Control Study ◽  
Case Control ◽  
Foot Ulcers ◽  
Vitamin B ◽  
Control Study

Motivation, effort and life circumstances as predictors of foot ulcers and amputations in people with Type 2 diabetes mellitus

2014 ◽  
Vol 31 (11) ◽  
pp. 1468-1476 ◽  
Author(s):  
C. Bruun ◽  
A. D. Guassora ◽  
A. B. S. Nielsen ◽  
V. Siersma ◽  
P. E. Holstein ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Foot Ulcers ◽  
Life Circumstances

scholarly journals Profile, Bacteriology and Antibiotic Susceptibility Pattern of Diabetic Foot Ulcers at Federal Medical Centre, Makurdi

2018 ◽  
Vol 1 (1) ◽  
pp. 53-60
Author(s):  
J E Ojobi ◽  
M O Ogiator ◽  
O B Anyim ◽  
M Abonyi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycaemic Control ◽  
Antibiotic Susceptibility ◽  
Foot Ulcers ◽  
Susceptibility Pattern ◽  
Poor Glycaemic Control ◽  
Antibiotic Susceptibility Pattern

The reported increase in the prevalence of diabetes mellitus is expected to be accompanied by a corresponding increase in associated complications. Foot problems are important public health complications of diabetes mellitus. A major obstacle in the management of foot ulcers in diabetes is the colonisation of wounds by virulent pathogens, increasing morbidity and mortality. This was a review of the profile, bacteriology and antibiotic susceptibility pattern of foot ulcers in type 2 diabetes mellitus to aid planning of services and provides a sensible approach to empirical antibiotic therapy while awaiting culture and sensitivity report. It was a hospital based retrospective study in individuals with type 2 diabetes mellitus admitted for foot ulcer(s) over a 3 year period (2012 - 2014) at the Federal Medical Centre. Approval for the study was obtained from the Ethics Committee of the institution. Relevant data (gender, age, residence, occupation, diabetes mellitus duration, ulcer duration, glycoslated haemoglobin status) were extracted from the files. One hundred and nine type 2 diabetes mellitus case files made up of 44 females and 65 males (1:1.5) with a mean age of 53.5±11.4 years were extracted. They were mostly farmers in their fifties with poor glycaemic control who had type 2 diabetes mellitus for more than a decade and foot ulcers for more than 6 months. Late presentation, poor glycaemic control, high rate of wound infection with Staphylococcus aureus, resistance to Penicillins and sensitivity to Quinolones were noted.

scholarly journals Interleukin-4 −33 C/T Gene Polymorphisms are not Associated with Type 2 Diabetes Mellitus

2020 ◽  
Vol 8 (A) ◽  
pp. 833-836
Author(s):  
Milahayati Daulay ◽  
Mutiara Indah Sari
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gene Polymorphism ◽  
Gene Polymorphisms ◽  
Interleukin 4 ◽  
Healthy Control ◽  
Different Populations

   BACKGROUND: Various studies have shown variations in the interleukin-4 (IL) gene associated with type 2 diabetes mellitus (T2DM) in different populations and ethnicities. AIM: The objective of this study was to determine the genetic variation of the IL-4 −33 C/T gene in some T2DM patients compared with healthy control in Medan, Sumatera Utara province, Indonesia. METHODS: DNA from T2DM patients and healthy control was isolated, then the determination of the IL-4 −33 C/T gene polymorphism was carried out using the polymerase chain reaction-restriction fragment length polymorphism technique. RESULTS: In all samples of this study, IL-4 −33 C/T gene polymorphisms were found in patients with T2DM and healthy control but were not statistically significant. CONCLUSION: The IL-4 −33 C/T gene polymorphism has no relationship with the incidence of T2DM in a portion of our population in Medan, Sumatera Utara province, Indonesia.

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