scholarly journals Reabilitação oral conservadora em paciente juvenil com alterações orofaciais secundárias ao tratamento de rabdomiossarcoma em cabeça e pescoço: relato de caso / Conservative oral rehabilitation in a juvenile patient with orofacial alterations secondary to the treatment of rhabdomyosarcoma in the head and neck: case report

2020 ◽  
Vol 65 (1) ◽  
pp. 1
Author(s):  
Paula Guimarães Moreira ◽  
Regina Maria Holanda de Mendonça ◽  
Paulo Sérgio Da Silva Santos ◽  
Katia Maria Coutinho Cappellaro ◽  
Luis Cândido Pinto da Silva
Keyword(s):  
Head And Neck ◽  
Developmental Disorders ◽  
Therapeutic Modality ◽  
Facial Growth ◽  
Oral Rehabilitation ◽  
The Face ◽  
Antineoplastic Treatment ◽  
Bone Anomalies ◽  
Juvenile Patient

Introdução: O tratamento antineoplásico multimodal para tumores em cabeça e pescoço de crianças frequentemente acarreta distúrbios de desenvolvimento em dentes e estruturas faciais. Dentre as alterações observadas estão as anomalias ósseas, agenesias dentárias, microdontia, anomalias de esmalte e, sobretudo, malformações radiculares e coronárias.A frequência e intensidade dessas alterações estão relacionadas com a idade da criança durante o tratamento, a modalidade terapêutica, o tipo de quimioterápico, a dose de radiação e o campo irradiado. Objetivo/Relato de Caso: Este trabalho tem como objetivo descrever o tratamento reabilitador oral conservador, por meio de confecção de prótese total superior do tipo overdenture, em paciente juvenil com severos distúrbios de desenvolvimento dentário e ósseo, consequentes do tratamento de rabdomiossarcoma em nasofaringe realizado aos dois anos de idade. Conclusão: Este relato enfatiza a importância do acompanhamento odontológico regular de pacientes pediátricos irradiados em face, até que o crescimento facial se complete, permitindo a manutenção da função e estética.Palavras Chave: Reabilitação bucal, Pediatria, Rabdomiossarcoma, Face, NasofaringeABSTRACTIntroduction: Multimodal antineoplastic treatment for tumors in the head and neck of children often leads to developmental disorders in teeth and facial structures. Among the alterations observed are bone anomalies, dental agenesis, microdontia, enamel anomalies and, mainly, root and coronary malformations. The frequency and intensity of these changes are related to the age of the child during treatment, the therapeutic modality, the type of chemotherapy, the radiation dose and the irradiated field. Aim/Report Case: This work aims to describe the conservative oral rehabilitation treatment, by means of the construction of a superior overdenture, in a patient with severe dental and bone developmental disorders resulting from the treatment of nasopharyngeal rhabdomyosarcoma performed at two years of age. Conclusion: This report emphasizes the importance of regular dental follow-up of pediatric irradiated patients on the face, until facial growth is complete, allowing maintenance of function and aesthetics.Keywords: Mouth rehabilitation, Pediatrics, Rhabdomyosarcoma, Face, Nasopharynx

scholarly journals Overdenture on dental remaining in oncological patients: Case report

2020 ◽  
Vol 23 (4) ◽  
pp. 7p
Author(s):  
Victoria Garcia De Carvalho ◽  
Cláudio Moreira Júnior ◽  
Lucio Murilo Dos Santos ◽  
Tarcísio José de Arruda Paes Júnior
Keyword(s):  
Head And Neck ◽  
Clinical Success ◽  
Oral Rehabilitation ◽  
Surgical Interventions ◽  
Oncological Patients ◽  
Total Cancer ◽  
Edentulous Patients ◽  
And Function ◽  
Head And Neck Radiotherapy

Head and neck cancer occupy the seventh place among the most common neoplasms in the world, with an annual incidence of approximately 640,000 new cases. Radiotherapy treatment has been highlighted, because there is greater tissue preservation, possibility of regression of the disease, decreased tumor volume, prevention of possible tumor recurrences and metastases, and even total cancer cure, but patients undergoing radiotherapy are at high risk of osteoradionecrosis if they perform surgical interventions in the region, such as dental implants and dental extraction, making prosthetic rehabilitation of partially edentulous patients after treating oral cancer something complex and often omitted; although it is a crucial factor in restoring oral function. Thus, the aim of the present study was to describe the planning, treatment and follow-up of a twelve-month prosthetic approach to rehabilitate the lower arch shape and function of a partially edentulous patient undergoing head and neck radiotherapy with a full denture mucus supported and tooth retained. After twelve months of follow-up, it was possible to evidence the functional and aesthetic clinical success, with preserved occlusal pattern, soft and bone tissue around[ and dental roots.KEYWORDSRadiotherapy; Head and Neck Neoplasms; Overdentures; Oral Rehabilitation.  

Antiretroviral Treatment-Associated Labia Majora Lipohypertrophy: A Rare Case and Plastic Surgical Treatment Options

2017 ◽  
Vol 2 (1) ◽  
pp. 43
Author(s):  
Akmal Hisham ◽  
Devananthan Ilenghoven ◽  
Wan Syazli Wan Ahmad Kamal ◽  
Salina Ibrahim ◽  
Shah Jumaat Mohd Yussof
Keyword(s):  
Highly Active Antiretroviral Therapy ◽  
Daily Living ◽  
Treatment Options ◽  
Hiv Positive ◽  
Highly Active ◽  
Labia Majora ◽  
The Face ◽  
Central Fat

The emergence of highly active antiretroviral therapy (HAART) has revolutionized the prognosis of HIV-infected patients. However, the extended use of HAART is associated with a disfiguring complication termed lipodystrophy, a disorder of body fat maldistribution causing peripheral fat loss (lipoatrophy) and central fat accumulation (lipohypertrophy). Lipoatrophy commonly affects the face, legs, buttocks and arm, whilst lipohypertrophy frequently favours the abdomen, breast and dorsocervical region. To our knowledge, we present only the second documented case in the literature of a labia majora lipohypertrophy in a HIV-positive patient receiving long-term HAART. The severity of labial abnormality caused significant physical and functional morbidities. Labiaplasty with dermolipectomy of the labia majora and excisional lipectomy of the mons pubis was successfully performed. At a 6-month follow-up, patient had no recurrence with resolution of symptoms and resumption of normal activities of daily living (ADL).

Long-Term Follow-up on an Intensified Treatment Regimen for Advanced Resectable Head and Neck Squamous Cell Carcinomas

2001 ◽  
Vol 19 (2) ◽  
pp. 127-136 ◽  
Author(s):  
John C. Grecula ◽  
David E. Schuller ◽  
Roy Smith ◽  
Chris A. Rhoades ◽  
Subir Nag ◽  
...  
Keyword(s):  
Head And Neck ◽  
Treatment Regimen ◽  
Squamous Cell ◽  
Squamous Cell Carcinomas ◽  
Long Term Follow Up

scholarly journals Control of Graves’ hyperthyroidism with very long-term methimazole treatment: a clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fereidoun Azizi ◽  
Hengameh Abdi ◽  
Atieh Amouzegar
Keyword(s):  
Low Dose ◽  
Reference Range ◽  
Antithyroid Drug ◽  
Therapeutic Modality ◽  
Thyroid Status ◽  
Antithyroid Drug Therapy ◽  
Daily Dose ◽  
Prevention Of Relapse

Abstract Background Long-term antithyroid drug therapy has become one of the options for treatment of Graves’ hyperthyroidism. The aim of this study was to compare thyroid status in those who discontinued methimazole (MMI) treatment after 12.8 years with those who continued MMI as long as 24 years. Methods Fifty nine patients with Graves’ disease on long-term MMI for 14.2 ± 2.9 years were recruited; 32 patients (54%) decided to discontinue MMI and 27 (46%) preferred additional years of MMI treatment. All patients were followed for a mean of 6 additional years. Results Of 27 patients who continued MMI up to 24 years, suppressed serum thyrotropin (TSH) was not observed in any patient after the seventh year of treatment. Serum free thyroxine, triiodothyronine, TSH and TSH receptor antibody concentrations remained normal up to the length of the study. Mean daily dose of MMI to maintain TSH in the reference range decreased gradually and reached to 2.8 ± 1.7 mg by 24 years of MMI treatment. No adverse reaction related to MMI occured during additional years of therapy. In 32 patients who discontinued MMI, hyperthyroidism relapsed in 6 patients (19%), one left follow-up and 25 (78%) remained euthyroid during the study. Conclusions Long-term low dose MMI treatment may be a lifelong effective and safe therapeutic modality in patients with Graves’ hyperthyroidism for prevention of relapse, if studies from other centers confirm findings of this research. Trial registration IRCT201009224794N1, 2010-10-25. Retrospectively registered. https://www.irct.ir/trial/5143.

Are voters too afraid to tackle corruption? Survey and experimental evidence from Mexico

2021 ◽  
pp. 1-19
Author(s):  
Omar García-Ponce ◽  
Thomas Zeitzoff ◽  
Leonard Wantchekon
Keyword(s):  
Political Behavior ◽  
Causal Effects ◽  
Willingness To Accept ◽  
Survey Experiment ◽  
Drug War ◽  
Mexican Drug War ◽  
The Face ◽  
Victims Of Crime ◽  
Nationally Representative

Abstract Are individuals in violent contexts reluctant to tackle corruption for fear of future violence? Or does violence mobilize them to fight corruption? We investigate these questions looking at the effects of fear and violence stemming from the Mexican Drug War on attitudes toward corruption. We conducted two surveys before the 2012 Mexican presidential election. First, as part of a nationally representative survey, we find a positive correlation between fear of violence and willingness to accept corruption in exchange for lower levels of violence. To disentangle causal effects, we conducted a follow-up survey experiment in Greater Mexico City where we manipulated fear over the Drug War. We find that individuals within this context are not easily scared. Those who received a common fear-inducing manipulation do not report higher levels of fear and are less willing to tolerate corruption. Conversely, we find strong evidence that individuals who have been victims of crime are more likely to report both higher levels of fear and willingness to accept corruption if it lowers violence. Our findings suggest that voters are more strategic and resilient in the face of violence than many extant theories of political behavior suggest.

Neutrophilic Dermatosis of Hands as Oncological Finding: Importance of Follow-Up

ORL ◽  
2021 ◽  
pp. 1-3
Author(s):  
Jérôme R. Lechien ◽  
Daphné Delplace ◽  
Mohamad Khalife ◽  
Sven Saussez
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Paraneoplastic Syndrome ◽  
Tobacco Consumption ◽  
Neutrophilic Dermatosis ◽  
Pharyngeal Cancer ◽  
Head And Neck Malignancy ◽  
Neck Malignancy

Neutrophilic febrile dermatosis (NFD) is a rare paraneoplastic syndrome that may be found in patients with head and neck cancer. NFD may appear before the neoplasia and may only concern the dorsal faces of the hands. This article reports the NFD findings of a patient with pharyngeal cancer, which was developed 2 years after the occurrence of NFD. The development of NFD in patient with alcohol and tobacco consumption should lead otolaryngologists and dermatologists to suspect head and neck malignancy. In cases of normal otolaryngological examination, patients have to be followed.

scholarly journals Effect of head and neck radiotherapy on the Eustachian tube functions

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Ahmed Abdullah Hamd ◽  
Essam Abd El-Wanes Behiry ◽  
Adel Tharwat Atallah ◽  
Sherif Maher Elaini ◽  
Ahmed Hamdy Alshafai
Keyword(s):  
Head And Neck ◽  
Eustachian Tube ◽  
Contralateral Side ◽  
Head And Neck Tumors ◽  
Eustachian Tube Dysfunction ◽  
Middle Ear Effusion ◽  
Neck Tumors ◽  
Tube Dysfunction ◽  
Ear Effusion

Abstract Background Nowadays, radiotherapy is widely used in management of many types of tumors including head and neck tumors; in this study, we concerned with its reverse effects on the Eustachian tube functions and if this effect is temporary or permanent. Results The whole (30) patients have tympanogram at both ears before starting radiotherapy; all patients (100%) were normal. In the immediate post radiotherapy tympanogram at the contralateral side, 6.7% of patients had effusion, and 20% had Eustachian tube dysfunction, while at the ipsilateral side, 20% of patients had effusion, and 33.3% had ET dysfunction. In the follow-up tympanogram 12 weeks post radiotherapy, we found that 6.7% of patients had effusion, and (10%) had Eustachian tube dysfunction at the contralateral side, while 6.7% of patients had effusion, and only 20% had Eustachian tube dysfunction at the ipsilateral side. Conclusion From this study, we concluded that patients with head and neck tumors treated by radiotherapy (apart from the nasopharynx) have a high incidence of affection of Eustachian tube function namely middle ear effusion and Eustachian tube dysfunction. The possibility for development of middle ear effusion and Eustachian tube dysfunction increases with increased tumor stage. Eustachian tube functions immediately post radiotherapy and after 12 weeks of the end of radiotherapy was affected by different effects according to the tumor site. The Eustachian tube functions significantly improved within 12 weeks after the last dose of radiotherapy, and we recommend audiological follow-up for patients with head and neck tumors treated with radiotherapy.

scholarly journals Effect of coronavirus disease 2019 on recurrences and follow up of head and neck squamous cell carcinoma

2021 ◽  
pp. 1-4
Author(s):  
E Kytö ◽  
E Haapio ◽  
I Kinnunen ◽  
H Irjala
Keyword(s):  
Squamous Cell Carcinoma ◽  
Prospective Study ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
One Year ◽  
Diagnostic Delays

Abstract Objective This prospective study aimed to evaluate possible diagnostic delays in head and neck squamous cell carcinoma recurrences due to the changed follow-up protocol during the coronavirus disease 2019 pandemic. Methods The follow-up appointments of head and neck squamous cell carcinoma patients treated more than one year prior to the pandemic were changed to telephone appointments in order to reduce physical visits to the hospital. All contacts, reasons for contact and recurrent cancers were recorded. Results There were 17 recurrences during a seven-month study period among 178 patients treated in the previous year (10 per cent); 14 of these recurrences occurred in patients whose treatment had ended less than one year previously and 3 occurred more than one year after treatment had ended. There was no delay in diagnoses of recurrent tumours or treatment despite reduced visits because of the coronavirus disease 2019 pandemic. Conclusion According to our analyses, no delay was caused in the diagnoses of recurrent diseases. Follow up by telephone or telemedicine can be considered as part of the follow-up protocol one year after the treatment of head and neck squamous cell carcinoma when necessary.

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