scholarly journals Studies into Exfoliation and Coating of Egyptian Blue for Application to the Detection of Latent Fingermarks

2020 ◽  
Author(s):  
Sorour Shahbazi ◽  
John Goodpaster ◽  
Gregory Smith ◽  
Thomas Becker ◽  
Simon W. Lewis
Keyword(s):  
Proof Of Concept ◽  
Concept Study ◽  
Egyptian Blue ◽  
Porous Surfaces ◽  
Alternative Approaches ◽  
Potential Improvement ◽  
Cetrimonium Bromide ◽  
Comprehensive Studies

We have recently demonstrated that exfoliated Egyptian blue powder coated with cetrimonium bromide is effective for detecting latent fingermarks on a range of highly-patterned non-porous surfaces (see reference). In this extension of that work, we here present our preliminary studies into alternative approaches to preparing exfoliated Egyptian blue with a variety of different coatings. The various powders were then applied to the detection of latent fingermarks on non-porous surfaces. This proof of concept study demonstrated that there is potential improvement in performance compared to our previous work, however more comprehensive studies are required to compare the quality of the fingermarks developed with these powders against particles exfoliated in water.

scholarly journals Studies into Exfoliation and Coating of Egyptian Blue for Application to the Detection of Latent Fingermarks

2020 ◽  
Author(s):  
Sorour Shahbazi ◽  
John Goodpaster ◽  
Gregory Smith ◽  
Thomas Becker ◽  
Simon W. Lewis
Keyword(s):  
Proof Of Concept ◽  
Concept Study ◽  
Egyptian Blue ◽  
Porous Surfaces ◽  
Alternative Approaches ◽  
Potential Improvement ◽  
Cetrimonium Bromide ◽  
Comprehensive Studies

We have recently demonstrated that exfoliated Egyptian blue powder coated with cetrimonium bromide is effective for detecting latent fingermarks on a range of highly-patterned non-porous surfaces (see reference). In this extension of that work, we here present our preliminary studies into alternative approaches to preparing exfoliated Egyptian blue with a variety of different coatings. The various powders were then applied to the detection of latent fingermarks on non-porous surfaces. This proof of concept study demonstrated that there is potential improvement in performance compared to our previous work, however more comprehensive studies are required to compare the quality of the fingermarks developed with these powders against particles exfoliated in water.

scholarly journals Studies into exfoliation and coating of Egyptian blue in methanol for application to the detection of latent fingermarks

2021 ◽  
Author(s):  
Sorour Shahbazi ◽  
John Goodpaster ◽  
Gregory Smith ◽  
Thomas Becker ◽  
Simon W. Lewis
Keyword(s):  
Porous Glass ◽  
Egyptian Blue ◽  
Glass Slides ◽  
Alternative Approach ◽  
Wide Range ◽  
Porous Surfaces ◽  
Males And Females ◽  
Cetrimonium Bromide ◽  
Comprehensive Study

We have recently demonstrated that coated exfoliated Egyptian blue powder is effective for detecting latent fingermarks on a range of highly-patterned non-porous and semi-porous surfaces. In this extension of that work, we present our studies into an alternative approach to prepare exfoliated Egyptian blue coated with cetrimonium bromide and Tween® 20 using a simpler technique. The quality of the latent fingermarks developed with these exfoliated powders and the commercial powder were compared in a comprehensive study. Depletion series of natural fingermarks from a wide range of donors (12 males and females) deposited on non-porous (glass slides) and semi-porous (Australian banknotes) surfaces were used in this study. Enhancement in the performance of the coated exfoliated particles compared to the commercial powder was observed, particularly in the case of aged fingermarks and polymer banknotes as challenging substrates.

scholarly journals A prescribed walking regimen plus arginine supplementation improves function and quality of life for patients with pulmonary arterial hypertension: a pilot study

2017 ◽  
Vol 8 (1) ◽  
pp. 204589321774396 ◽  
Author(s):  
Mary Beth Brown ◽  
Attie Kempf ◽  
Catherine M. Collins ◽  
Gary M. Long ◽  
Matthew Owens ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Current Evidence ◽  
Proof Of Concept ◽  
Concept Study ◽  
Sf 36 ◽  
Pulmonary Arterial ◽  
Arginine Supplementation

Current evidence suggests that exercise training is beneficial in pulmonary arterial hypertension (PAH). Unfortunately, the standard supervised, hospital-based programs limit patient accessibility to this important intervention. Our proof-of-concept study aimed to provide insight into the usefulness of a prescribed walking regimen along with arginine supplementation to improve outcomes for patients with PAH. Twelve PAH patients (all women) in New York Heart Association (NYHA) functional class (FC) II (n = 7) or III (n = 5) and in stable condition for ≥ 3 months were enrolled. Patients performed home- and fitness-center- based walking at 65–75% heart rate (HR) reserve for 45 min, six sessions/week for 12 weeks. Concomitant L-arginine supplementation (6000 mg/day) was provided to maximize beneficial endothelial training adaptations. Cardiopulmonary exercise testing, 6-min walk testing (6MWT), echocardiography, laboratory studies, and quality of life (QoL) survey (SF-36) were performed at baseline and 12 weeks. Eleven patients completed the study (72 session adherence rate = 96 ± 3%). Objective improvement was demonstrated by the 6MWT distance (increased by 40 ± 13 m, P = 0.01), VO2max (increased by 2 ± 0.7 mL/kg/min, P = 0.02), time-to-VO2max (increased by 2.5 ± 0.6 min, P = 0.001), VO2 at anaerobic threshold (increased by 1.3 ± 0.5 mL/kg/min, P = 0.04), HR recovery (reduced by 68 ± 23% in slope, P = 0.01), and SF-36 subscales of Physical Functioning and Energy/Fatigue (increased by 70 ± 34% and 74 ± 34%, respectively, P < 0.05). No adverse events occurred, and right ventricular function and brain natriuretic peptide levels remained stable, suggesting safety of the intervention. This proof-of-concept study indicates that a simple walking regimen with arginine supplementation is a safe and efficacious intervention for clinically stable PAH patients, with gains in objective function and QoL measures. Further investigation in a randomized controlled trial is warranted.

scholarly journals Mapping drinking water and quality of life aspects in urban settings: an application of the urban exposome

2018 ◽  
Author(s):  
Xanthi D. Andrianou ◽  
Chava van der Lek ◽  
Pantelis Charisiadis ◽  
Solomon Ioannou ◽  
Kalliopi N. Fotopoulou ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Water Quality ◽  
Drinking Water ◽  
Health Status ◽  
Quality Parameters ◽  
Drinking Water Quality ◽  
Water Quality Parameters ◽  
Proof Of Concept ◽  
Concept Study

AbstractCities face rapid changes leading to increasing inequalities and emerging public health issues that require cost-effective interventions. The urban exposome framework constitutes a novel approach in tackling city-wide challenges, such as those of drinking water quality and quality of life. In this proof-of-concept study, we presented part of the urban exposome of Limassol (Cyprus) focusing on chemical and microbial drinking water quality parameters and their association with urban neighborhood indicators. A perceptions study and an urban population study was conducted. We mapped the water quality parameters and participants’ opinions on city life (i.e. neighborhood life, health care and green space access) using quarters (small administrative areas) as the reference unit of the city. In an exploratory environment-wide association study analysis, we used all variables (questionnaire responses and water quality metrics) to describe correlations between them accounting, also, for self-reported health status. Overall, urban drinking-water quality using conventional indicators of chemical (disinfection byproducts-trihalomethanes) and microbial (coliforms, E. coli, and Enterococci) quality did not raise particular concerns. The general health and chronic health status of the urban participants were significantly (all >FDR corrected p value of 0.1) associated with different health conditions such as hypertension and asthma, or having financial issues in access to dental care. Additionally, correlations between trihalomethanes and participant characteristics (e.g. household cleaning, drinking water habits) were documented. This proof-of-concept study showed the potential of using integrative approaches to develop urban exposomic profiles and identifying within-city differentiated environmental and health indicators. The characterization of the urban exposome of Limassol will be expanded via the inclusion of biomonitoring tools and untargeted metabolomics platforms.

scholarly journals Baduanjin Qigong Intervention by Telerehabilitation (TeleParkinson): A Proof-of-Concept Study in Parkinson’s Disease

2021 ◽  
Vol 18 (13) ◽  
pp. 6990
Author(s):  
Livia P. Carvalho ◽  
Simon Décary ◽  
Isabelle Beaulieu-Boire ◽  
Rosalie Dostie ◽  
Isabelle Lalonde ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Patient Satisfaction ◽  
Adverse Events ◽  
Proof Of Concept ◽  
Concept Study ◽  
Supervised Exercise ◽  
Patient Reported

Many people living with Parkinson’s Disease (PD) face issues with healthcare services, including delays in diagnosis and treatment, as well as limited access to specialized care, including rehabilitation programs. Non-motor and motor signs and symptoms typically observed in people with PD, such as tremor, rigidity, postural instability, bradykinesia, and freezing are particularly disabling and have been associated with falls, fractures, hospitalizations, and a worse quality of life. Baduanjin Qigong (BDJ) programs have been proven potentially effective in improving physical outcomes and reducing the incidence of falls in PD. The aim of this case report, proof-of-concept, study was to explore the adherence, feasibility, acceptability, and potential efficacy of a BDJ program offered via telerehabilitation in people with PD living in the community. Two participants performed semi-supervised exercise sessions at home, twice a week (over eight weeks) using the TeraPlus platform. Adherence, adverse events, and feasibility (technical implementability), acceptability (patient satisfaction), patient-reported, self-reported, and performance outcomes were measured. Results were based on single-subject descriptive data, minimal detectable change, and anchor-based minimally important difference. Our findings suggest that the intervention seems feasible with no major technical issues or adverse events, and high adherence; acceptable (patient satisfaction); and potentially effective to improve markers of walking performance (gait speed, balance), and quality of life (activities of daily living, mobility).

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