A Simple Algorithm for Despiking Raman Spectra

2018 ◽  
Author(s):  
Darren Whitaker ◽  
Kevin Hayes

Raman Spectroscopy is a widely used analytical technique, favoured when molecular specificity with minimal sample preparation is required.<br>The majority of Raman instruments use charge-coupled device (CCD) detectors, these are susceptible to cosmic rays and as such multiple spurious spikes can occur in the measurement. These spikes are problematic as they may hinder subsequent analysis, particularly if multivariate data analysis is required. In this work we present a new algorithm to remove these spikes from spectra after acquisition. Specifically we use calculation of modified <i>Z</i> scores to locate spikes followed by a simple moving average filter to remove them. The algorithm is very simple and its execution is essentially instantaneous, resulting in spike-free spectra with minimal distortion of actual Raman data. The presented algorithm represents an improvement on existing spike removal methods by utilising simple, easy to understand mathematical concepts, making it ideal for experts and non-experts alike. <br>

2018 ◽  
Author(s):  
Darren Whitaker ◽  
Kevin Hayes

Raman Spectroscopy is a widely used analytical technique, favoured when molecular specificity with minimal sample preparation is required.<br>The majority of Raman instruments use charge-coupled device (CCD) detectors, these are susceptible to cosmic rays and as such multiple spurious spikes can occur in the measurement. These spikes are problematic as they may hinder subsequent analysis, particularly if multivariate data analysis is required. In this work we present a new algorithm to remove these spikes from spectra after acquisition. Specifically we use calculation of modified <i>Z</i> scores to locate spikes followed by a simple moving average filter to remove them. The algorithm is very simple and its execution is essentially instantaneous, resulting in spike-free spectra with minimal distortion of actual Raman data. The presented algorithm represents an improvement on existing spike removal methods by utilising simple, easy to understand mathematical concepts, making it ideal for experts and non-experts alike. <br>


2018 ◽  
Author(s):  
Darren Whitaker ◽  
Kevin Hayes

Raman Spectroscopy is a widely used analytical technique, favoured when molecular specificity with minimal sample preparation is required.<br>The majority of Raman instruments use charge-coupled device (CCD) detectors, these are susceptible to cosmic rays and as such multiple spurious spikes can occur in the measurement. These spikes are problematic as they may hinder subsequent analysis, particularly if multivariate data analysis is required. In this work we present a new algorithm to remove these spikes from spectra after acquisition. Specifically we use calculation of modified <i>Z</i> scores to locate spikes followed by a simple moving average filter to remove them. The algorithm is very simple and its execution is essentially instantaneous, resulting in spike-free spectra with minimal distortion of actual Raman data. The presented algorithm represents an improvement on existing spike removal methods by utilising simple, easy to understand mathematical concepts, making it ideal for experts and non-experts alike. <br>


2020 ◽  
Vol 65 (6) ◽  
pp. 705-720
Author(s):  
Aarti Sharma ◽  
Jaynendra Kumar Rai ◽  
Ravi Prakash Tewari

AbstractEpilepsy is characterized by uncontrollable seizure during which consciousness of patient is disturbed. Prediction of the seizure in advance will increase the remedial possibilities for the patients suffering from epilepsy. An automated system for seizure prediction is important for seizure enactment, prevention of sudden unexpected deaths and to avoid seizure related injuries. This paper proposes the prediction of an upcoming seizure by analyzing the 23 channel non-stationary EEG signal. EEG signal is divided into smaller segments to change it into quasi-stationary data using an overlapping moving window. Brain region is marked into four regions namely left hemisphere, right hemisphere, central region and temporal region to identify the epileptogenic region. The epileptogenic region shows significant variations during pre-ictal state in comparison to the other regions. So, seizure prediction is carried out by analyzing EEG signals from this region. Seizure prediction is proposed using features extracted from both time and frequency domain. Relative entropy and relative energy are extracted from wavelet transform and Pearson correlation coefficient is obtained from time domain EEG signal. Extracted features have been smoothened using moving average filter. First order derivative of relative features have been used to normalize the intervariability before deciding the threshold for marking the prediction of seizure. Isolated seizures where pre-ictal duration of more than 1 h is reported has been detected with an accuracy of 92.18% with precursory warning 18 min in advance and seizure confirmation 12 min in advance. An overall accuracy of 83.33% with false positive alarm rate of 0.01/h has been obtained for all seizure cases with average prediction time of 9.9 min.


2014 ◽  
Vol 116 ◽  
pp. 276-283 ◽  
Author(s):  
Naji Rajai Nasri Ama ◽  
Wilson Komatsu ◽  
Lourenco Matakas Junior

Author(s):  
Jinshan Cao ◽  
Xiuxiao Yuan ◽  
Jianya Gong

Due to the large biases between the laboratory-calibrated values of the orientation parameters and their in-orbit true values, the initial direct georeferencing accuracy of the Ziyuan-3 (ZY-3) three-line camera (TLC) images can only reach the kilometre level. In this paper, a point-based geometric calibration model of the ZY-3 TLCs is firstly established by using the collinearity constraint, and then a line-based geometric calibration model is established by using the coplanarity constraint. With the help of both the point-based and the line-based models, a feasible in-orbit geometric calibration approach for the ZY-3 TLCs combining ground control points (GCPs) and ground control lines (GCLs) is presented. Experimental results show that like GCPs, GCLs can also provide effective ground control information for the geometric calibration of the ZY-3 TLCs. The calibration accuracy of the look angles of charge-coupled device (CCD) detectors achieved by using the presented approach reached up to about 1.0''. After the geometric calibration, the direct georeferencing accuracy of the ZY-3 TLC images without ground controls was significantly improved from the kilometre level to better than 11 m in planimetry and 9 m in height. A more satisfactory georeferencing accuracy of better than 3.5 m in planimetry and 3.0 m in height was achieved after the block adjustment with four GCPs.


2016 ◽  
Vol 71 (5) ◽  
pp. 988-995 ◽  
Author(s):  
Patrick D. Barnett ◽  
S. Michael Angel

A spatial heterodyne Raman spectrometer (SHRS) with millimeter-sized optics has been coupled with a standard cell phone camera as a detector for Raman measurements. The SHRS is a dispersive-based interferometer with no moving parts and the design is amenable to miniaturization while maintaining high resolution and large spectral range. In this paper, a SHRS with 2.5 mm diffraction gratings has been developed with 17.5 cm−1 theoretical spectral resolution. The footprint of the SHRS is orders of magnitude smaller than the footprint of charge-coupled device (CCD) detectors typically employed in Raman spectrometers, thus smaller detectors are being explored to shrink the entire spectrometer package. This paper describes the performance of a SHRS with 2.5 mm wide diffraction gratings and a cell phone camera detector, using only the cell phone’s built-in optics to couple the output of the SHRS to the sensor. Raman spectra of a variety of samples measured with the cell phone are compared to measurements made using the same miniature SHRS with high-quality imaging optics and a high-quality, scientific-grade, thermoelectrically cooled CCD.


Sensors ◽  
2019 ◽  
Vol 19 (18) ◽  
pp. 3997 ◽  
Author(s):  
Tam Nguyen ◽  
Xiaoli Qin ◽  
Anh Dinh ◽  
Francis Bui

A novel R-peak detection algorithm suitable for wearable electrocardiogram (ECG) devices is proposed with four objectives: robustness to noise, low latency processing, low resource complexity, and automatic tuning of parameters. The approach is a two-pronged algorithm comprising (1) triangle template matching to accentuate the slope information of the R-peaks and (2) a single moving average filter to define a dynamic threshold for peak detection. The proposed algorithm was validated on eight ECG public databases. The obtained results not only presented good accuracy, but also low resource complexity, all of which show great potential for detection R-peaks in ECG signals collected from wearable devices.


1991 ◽  
Vol 9 (1) ◽  
pp. 158-159 ◽  
Author(s):  
B. D. Carter ◽  
M. C. B. Ashley

AbstractWe describe the application of Peltier effect cooling to charge coupled device (CCD) detectors. We are developing this technique to produce a CCD camera which requires low maintenance, yet has sufficiently small dark-current for long exposure imaging. This camera will be used in an automated imaging telescope at Siding Spring Observatory. The design principles used to maximise cooling of the detector, and hence minimise dark-current, are discussed. A small dark-current can be obtained only if great care is taken to reduce or eliminate convective, conductive and radiative heating of the chip. In addition, a path of high thermal conductivity must be provided for the heat removed from the CCD. A recent laboratory test of our cooling system demonstrates that careful design can lead to sufficiently low CCD dark-current for many astronomical applications.


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