scholarly journals Role of fixed combinations in modern treatment of arterial hypertension: new or well overlooked old?

2019 ◽  
Vol 16 (4) ◽  
pp. 33-37
Author(s):  
Tatiana V Adasheva ◽  
Elena I Samorukova ◽  
Vladimir S Zadionchenko ◽  
Kristina A Laricheva
Keyword(s):  
Arterial Hypertension ◽  
Treatment Adherence ◽  
European Society ◽  
Fixed Combination ◽  
Combined Therapy ◽  
Rapid Change ◽  
Therapeutic Strategies ◽  
Treatment Algorithms ◽  
European Society Of Cardiology

The article discusses therapeutic tactics changes and arterial hypertension (AH) treatment algorithms stated in latest European Society of Hypertension and European Society of Cardiology guidelines (ESH/ESC 2018). Causes of therapeutic strategies ineffectiveness are analyzed: therapeutical persistency, insufficient use of combined therapy, treatment adherence problems, and “complexity” of therapeutic strategies used. Stages of combined AH therapy history and treatment with fixed combinations renaissance in the 1990s are described. Special attention is given to triple-component fixed combination for AH treatment. Therapeutic strategy of rapid change to triple-component antihypertensive therapy in case of double-component schemes non-effectiveness is explained. The latest expert consensus, mataanalyses, and studies explaining fundamental principles of AH control increase in population are presented. Mechanisms of AH treatment adherence increase are analyzed. Results of the latest study of amlodipine/indapamide/perindopril fixed combination use effectiveness, safety, and treatment adherence are analyzed independently.

scholarly journals Approaches to the Diagnosis and Treatment of Arterial Hypertension in the Light of European Recommendations

Kardiologiia ◽  
2019 ◽  
Vol 59 (9) ◽  
pp. 64-70
Author(s):  
V. N. Larina ◽  
B. Ya. Bart ◽  
E. A. Vartanian ◽  
E. V. Fedorova ◽  
M. P. Mikhailusova ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Drug Treatment ◽  
Arterial Hypertension ◽  
European Society ◽  
Initial Therapy ◽  
Ambulatory Bp Monitoring ◽  
Single Pill ◽  
European Society Of Cardiology

In this review we present analysis the European recommendations on hypertension – what’s new and what has changed in the tactics of managing patients with arterial hypertension (AH). We compared recommendations on hypertension of the European Society of Cardiology (ESC) and the European Society of hypertension (ESH) 2018 with European recommendations of previous years. In the updated version of guidelines, it is still recommended to determine AH as blood pressure (BP) ≥140 and / or ≥90 mm Hg; to subdivide BP levels into optimal, normal, and high normal, to classify severity of AH as 3 degrees, and to distinguish separately its isolated systolic form. Values for out-of-office BP remained unchanged, but recommendations emerged concerning wider use of ambulatory BP monitoring and self-measurement of BP. For initial therapy, it was recommended to use two drugs combinations preferably as single pill combinations. An increase of the role of nurses and pharmacists in teaching, supporting patients and controlling hypertension has been noted. This can improve the achievement of target BP and, as a result, reduce the cardiovascular risk. New European recommendations highlight the modern aspects of classification and diagnosis of AH, main stages of screening, and algorithm of drug treatment of AH.

scholarly journals GUIDELINES ON ARTERIAL HYPERTENSION MANAGEMENT OF THE EUROPEAN SOCIETY OF CARDIOLOGY AND EUROPEAN SOCIETY OF HYPERTENSION 2018: WHAT’S NEW?

The Clinician ◽  
2018 ◽  
Vol 12 (2) ◽  
pp. 10-15
Author(s):  
A. A. Klimenko ◽  
D. A. Anichkov ◽  
N. A. Demidova
Keyword(s):  
Arterial Hypertension ◽  
European Society ◽  
Beta Blockers ◽  
Ambulatory Monitoring ◽  
White Coat Hypertension ◽  
General Strategy ◽  
Masked Hypertension ◽  
Angiotensin Ii Receptor ◽  
European Society Of Cardiology ◽  
Selection Of

The article considers the key points of the new 2018 guidelines of the European Society of Cardiology and European Society of Hypertension on management and treatment of patients with arterial hypertension (AH). The guidelines widen the possibilities for ambulatory monitoring of blood pressure (BP) and at-home measurement of BP in diagnosis of AH, especially for detection of hidden (“masked”) hypertension and white-coat hypertension. New target ranges for BP depending on age and concomitant pathology are established. For most patients, BP <140 mm Hg (primary target) is accepted, for patients under 65 years if therapy is well-tolerated BP <130 mm Hg should be achieved. Selection of treatment for elderly patients shouldn’t be based on chronological age but on biological age taking into account evaluation of senile asthenia, self-maintenance and therapy tolerability. For starting selection of drugs for AH, in most patients two-component therapy (one pill drug) is preferable. The latest guidelines contain simplified algorithms for management of patients with AH. It is shown that in most patients, a preference should be made for combinations of renin-angiotensin-aldosterone system blocker (inhibitors of angiotensin-converting enzyme or angiotensin II receptor blockers) with a slow calcium channels blocker and/or thiazide/thiazide-like diuretic. Beta-blockers should be prescribed only for specific clinical cases. Special emphasis is made on evaluation of patient’s treatment adherence as the main reason for insufficient BP control, as well as on increased role of nurses and pharmacists in education, monitoring, and support of patients with AH being an important part of general strategy of BP control.

scholarly journals Dart to the target: an alternative bull’s eye parametric display for European Society of Cardiology / European Respiratory Society goal-orientated risk reduction strategy in pulmonary arterial hypertension

2018 ◽  
Vol 8 (3) ◽  
pp. 204589401878052
Author(s):  
Cihangir Kaymaz ◽  
Ozgur Yasar Akbal ◽  
Aykun Hakgor ◽  
Hacer Ceren Tokgoz ◽  
Seda Tanyeri
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Risk Reduction ◽  
European Society ◽  
European Respiratory Society ◽  
Reduction Strategy ◽  
Risk Reduction Strategy ◽  
Pulmonary Arterial ◽  
European Society Of Cardiology ◽  
Bull's Eye

Despite the significant mortality and mobidity benefits being obtained with the targeted therapies in patients with pulmonary arterial hypertension (PAH), mid- to long-term survival of patients with this disease has remained unsatisfactory. For earlier and reliable risk stratification in PAH and tailoring the dynamic management strategies, various risk assessment models have been developed. Currently available risk reduction strategy recommended by the European Society of Cardiology (ESC)/European Respiratory Society (ERS) 2015 Pulmonary Hypertension Guidelines has been utilized in three recent registries. In this review, we evaluated the risk prediction models and management algorithms in this setting and propose an alternative parametric display, a bull’s eye, dart table scheme for ESC/ERS goal-orientated risk reduction strategy in patients with PAH.

Sport and arrhythmias: summary of an international symposium

2007 ◽  
Vol 14 (5) ◽  
pp. 707-714 ◽  
Author(s):  
Franco Giada ◽  
Serge S. Barold ◽  
Alessandro Biffi ◽  
Bruno De Piccoli ◽  
Pietro Delise ◽  
...  
Keyword(s):  
Sudden Death ◽  
Risk Stratification ◽  
International Symposium ◽  
European Society ◽  
Cardiac Arrhythmias ◽  
Exercise Prescription ◽  
International Workshop ◽  
Sport And Exercise ◽  
European Society Of Cardiology

This article is the report of an International Symposium endorsed by the European Society of Cardiology, held within the Venice Arrhythmias 2007: 10th International Workshop on Cardiac Arrhythmias (Venice, October 2007). The topics of the Symposium are the following: how to stratify the risk of sudden death in the athletes; the role of different diagnostic examinations in the risk stratification of sudden death in the athletes; controversies on arrhythmias and sport; and exercise prescription in patients with arrhythmias. Eur J Cardiovasc Prev Rehabil14:707-714 © 2007 The European Society of Cardiology

scholarly journals 2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC)

2013 ◽  
Vol 31 (10) ◽  
pp. 1925-1938 ◽  
Author(s):  
Giuseppe Mancia ◽  
Robert Fagard ◽  
Krzysztof Narkiewicz ◽  
Josep Redán ◽  
Alberto Zanchetti ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Practice Guidelines ◽  
European Society ◽  
European Society Of Cardiology
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