scholarly journals Gardenia ternifolia Schum. & Thonn. (Rubiaceae): Review of medicinal uses, phytochemistry and biological activities

2020 ◽  
Vol 11 (4) ◽  
pp. 5876-5885
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Democratic Republic Of Congo ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Tropical Africa ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information

Gardenia ternifolia Schum. & Thonn. is a shrub or small tree widely used as a traditional medicine throughout its distributional range in tropical Africa. Gardenia ternifolia is widespread in tropical Africa, extending from Senegal eastwards to Ethiopia and Kenya, through the Democratic Republic of Congo (DRC) southwards to Namibia, South Africa and Mozambique. This study was aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of G. ternifolia. Documented information on the medicinal uses, phytochemistry and biological activities of G. ternifolia was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study showed that the species is widely used as an aphrodisiac and protective charm, and traditional medicine for headache, migraine, respiratory infections, sore eyes, hypertension, diabetes, gastro-intestinal problems, erectile dysfunction, malaria, convulsions and epilepsy. Phytochemical compounds identified from the species include alkaloids, anthocyanins, coumarins, flavonoids, phenols, quinones, saponins, steroids, stereoisomeric neolignans, tannins and terpenoids. Pharmacological research revealed that G. ternifolia extracts and compounds isolated from the species have antibacterial, antiviral, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antisickling, antitheilerial, hepatotoxicity, larvicidal and cytotoxicity activities. Future research on G. ternifolia should focus on detailed phytochemical evaluations, including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.

Evaluation of Medicinal uses, Phytochemistry and Biological Activities of Adenia gummifera (Harv.) Harms -

2020 ◽  
Vol 10 (5) ◽  
pp. 280-286
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Democratic Republic Of Congo ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities

Adenia gummifera (Harv.) Harms is a climber or liane widely used as traditional medicine throughout its distributional range in tropical Africa. Adenia gummifera occurs naturally in the Democratic Republic of Congo (DRC), Eswatini, Ethiopia, Kenya, Malawi, Mozambique, Seychelles, Somalia, South Africa, Tanzania, Uganda, Zambia and Zimbabwe. This study is aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of A. gummifera. Documented information on the medicinal uses, phytochemistry and biological activities of A. gummifera was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications sourced from the university library. This study showed that the species is widely used as an emetic and a protective charm, and, as traditional medicine for infertility, sexually transmitted infections, gastro-intestinal infections, leprosy, respiratory infections, malaria and menstrual problems. Phytochemical compounds identified from the species include polyacetylenic diepoxide, alkaloids, flavonoids, flavonol, modeccin, proanthocyanidins, tetraphyllin, phenolics, polyphenol and tannins. Pharmacological research revealed that A. gummifera extracts and compounds isolated from the species have antibacterial, antifungal, acetylcholinesterase inhibitory (AChEI), anaesthetic, antioxidant, antiplasmodial and cytotoxicity activities. Future research on A. gummifera should focus on detailed phytochemical evaluations including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.

scholarly journals Gardenia volkensii K. Schum. (Rubiaceae): Review of Medicinal uses, Phytochemistry and Biological Activities -

2020 ◽  
Vol 10 (5) ◽  
pp. 175-181
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Sexually Transmitted ◽  
Additional Information ◽  
Cytotoxicity Activities

Gardenia volkensii K. Schum. is a shrub or small tree widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of G. volkensii. Documented information on the medicinal uses, phytochemistry and biological activities of G. volkensii was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications sourced from the university library. The articles published between 1972 and 2020 were used in this study. This study showed that the species is widely used as emetic and protective charm, and as traditional medicine for infertility, sore eyes, sexually transmitted infections, headache, gastro-intestinal infections, earache, convulsions, epilepsy and respiratory infections. Phytochemical compounds identified from the species include aldehydes, benzenoids, cinnamates, coumarins, essential oils, fatty acids, flavonoids, iridoids, phenolics, phytosterols and triterpenoids. Pharmacological research revealed that G. volkensii extracts and compounds isolated from the species have antibacterial, antifungal, antioxidant, mutagenic and antimutagenic and cytotoxicity activities. Future research on G. volkensii should focus on detailed phytochemical evaluations including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.

Baccharoides lasiopus: Review of its Medicinal uses, Phytochemistry and Pharmacological Properties -

2020 ◽  
Vol 10 (5) ◽  
pp. 205-212
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Skin Diseases ◽  
Respiratory Infections ◽  
Sesquiterpene Lactones ◽  
Future Research ◽  
Pharmacological Properties ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Phytochemical Compounds

Baccharoides lasiopus is a woody shrub widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry, and medicinal uses of B. lasiopus. Documented information on the pharmacological properties, phytochemistry, and medicinal uses of B. lasiopus was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. The articles published between 1971 and 2020 were used in this study. This study showed that the leaves, roots, stems, whole plant parts, root and stem bark of B. lasiopus are widely used as galactagogue, purgative and anthelmintic, and traditional medicine for headache, liver diseases, skin diseases, respiratory infections, malaria, augment labour, convulsions, epilepsy, fainting, female reproductive problems, and gastro-intestinal problems. Phytochemical compounds identified from the species include elemanolide type sesquiterpene lactones, alkaloids, anthraquinones, cardiac glycosides, coumarins, flavonoids, phenolics, reducing sugars, saponins, steroids, tannins, terpenoids, and xanthines. Pharmacological research revealed that B. lasiopus extracts and compounds isolated from the species have anthelmintic, antibacterial, antifungal, antiviral, antihyperglycemic, antiplasmodial, antimalarial, antiprotozoal, haematological, hepatoprotective, hepatotoxicity, larvicidal, and cytotoxicity activities. Future research on B. lasiopus should focus on the possible biochemical mechanisms of action of both the crude extracts and identified phytochemical compounds including toxicological, in vivo, and clinical studies to corroborate the traditional medical applications of the species.

scholarly journals HELICHRYSUM CYMOSUM (L.) D.DON (ASTERACEAE): MEDICINAL USES, CHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 19-26
Author(s):  
ALFRED MAROYI
Keyword(s):  
Biological Activities ◽  
Future Research ◽  
Pharmacological Properties ◽  
Journal Articles ◽  
Tropical Africa ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities ◽  
The University ◽  
Anti Hiv

Helichrysum cymosum is a valuable and well-known medicinal plant in tropical Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. cymosum. Information on medicinal uses, phytochemistry and biological activities of H. cymosum, was collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that H. cymosum is traditionally used as a purgative, ritual incense, and magical purposes and as herbal medicine for colds, cough, fever, headache, and wounds. Ethnopharmacological research revealed that H. cymosum extracts and compounds isolated from the species have antibacterial, antioxidant, antifungal, antiviral, anti-HIV, anti-inflammatory, antimalarial, and cytotoxicity activities. This research showed that H. cymosum is an integral part of indigenous pharmacopeia in tropical Africa, but there is lack of correlation between medicinal uses and existing pharmacological properties of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. cymosum extracts and compounds isolated from the species.

scholarly journals HELICHRYSUM PETIOLARE HILLIARD AND B. L. BURTT: A REVIEW OF ITS MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 32-37 ◽  
Author(s):  
ALFRED MAROYI
Keyword(s):  
South Africa ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Journal Articles ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities ◽  
The University ◽  
Phytochemical Studies

Helichrysum petiolare is a valuable and well-known medicinal herb in South Africa. A comprehensive review of phytochemical, medicinal uses, and biological activities of H. petiolare is presented in this study. Information on biological activities, medicinal uses, and phytochemistry of H. petiolare was gathered from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information on these aspects was sourced from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. The current study revealed that H. petiolare is mainly used as herbal medicine for respiratory infections, diabetes, fever, headache, heart problem, high blood pressure, pain, reproductive problems, and wounds. Phytochemical studies showed that H. petiolare extracts and compounds isolated from the species have antifungal, anti-inflammatory, antibacterial, antioxidant, antityrosinase, antigenotoxicity, and cytotoxicity activities. This research showed that H. petiolare is an integral part of indigenous pharmacopeia in South Africa, but there is the lack of alignment between the known medicinal applications, phytochemistry, and biological activities of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. petiolare extracts and compounds associated with the species.

scholarly journals BALANITES MAUGHAMII SPRAGUE (ZYGOPHYLLACEAE) IN TROPICAL AFRICA: A SYNTHESIS AND REVIEW OF ITS CHEMISTRY, PHARMACOLOGY, AND MEDICINAL POTENTIAL

2019 ◽  
pp. 85-90
Author(s):  
ALFRED MAROYI
Keyword(s):  
Biological Activities ◽  
Future Research ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information ◽  
Fish Poison ◽  
Documented Information ◽  
Phytochemical Compounds ◽  
The University ◽  
Online Sources

Balanites maughamii is an important medicinal plant species in Southern Africa. This study is aimed at providing a critical review of the biological activities, phytochemistry, and medicinal uses of B. maughamii. Documented information on biological activities, medicinal uses, and phytochemistry of B. maughamii was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the biological activities, phytochemistry and medicinal uses of B. maughamii were collected from pre-electronic sources such as book chapters, books, journal articles, theses, and scientific publications sourced from the university library. This study showed that the bark, fruits, leaves, and roots of B. maughamii are traditionally used for magical purposes, as emetic, tonic, fish poison, insecticidal, and herbal medicine for bilharzia. Phytochemical compounds identified from the bark, fruits, and leaves of B. maughamii are aliphatic alcohols, aliphatic ketones, benzenoid compounds, aliphatic acids, amino acids, coumarin, aliphatic esters, flavonoids, aliphatic aldehydes, and sterol. Pharmacological research revealed that B. maughamii extracts have adulticidal, antibacterial, antiplasmodial, bitterness, molluscicidal, and mutagenic activities. Future research should focus on evaluating the phytochemical, pharmacological, and toxicological properties of B. maughamii crude extracts as well as compounds isolated from the species.

scholarly journals SCABIOSA COLUMBARIA: A REVIEW OF ITS MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 10-14
Author(s):  
ALFRED MAROYI
Keyword(s):  
Herbal Medicine ◽  
Biological Activities ◽  
Perennial Herb ◽  
Future Research ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Respiratory Problems ◽  
Plant Parts ◽  
Additional Information ◽  
Aerial Parts

Scabiosa columbaria is a perennial herb widely used as herbal medicine throughout its distributional range in tropical Africa, Asia, and Europe. This study is aimed at providing a critical review of the biological activities, phytochemistry, and medicinal uses of S. columbaria. Documented information on biological activities, medicinal uses, and phytochemistry of S. columbaria was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, ScienceDirect, Elsevier, PubMed, and Web of Science. Additional information on the biological activities, phytochemistry, and medicinal uses of S. columbaria was gathered from pre-electronic sources such as book chapters, books, journal articles, theses, and scientific publications sourced from the university library. This study showed that the aerial parts, leaves, roots, stems, and the whole plant parts of S. columbaria are used as colic, love charm and for magical purposes, and as herbal medicine for eye problems, heartburn, respiratory problems, wounds, female infertility, venereal diseases, skin infections, and menstrual problems. Phytochemical compounds identified from the aerial parts and roots of S. columbaria are glycoside scabiosin, loganin, sweroside, palmitic acid, phthalic acid, diisooctyl phthalate, bis-(ethylhexyl) phthalate, and dibutyl phthalate. Pharmacological research revealed that S. columbaria extracts and compounds have antibacterial, antifungal, and antiprotozoan activities. Future research should focus on evaluating the phytochemical, pharmacological, and toxicological properties of S. columbaria crude extracts as well as compounds isolated from the species.

scholarly journals Chemical properties, biological activities and ethnomedicinal uses of Maerua pseudopetalosa: A famine food species of tropical Africa

2020 ◽  
Vol 11 (4) ◽  
pp. 7889-7897
Author(s):  
Alfred Maroyi
Keyword(s):  
Traditional Medicine ◽  
Democratic Republic Of Congo ◽  
Biological Activities ◽  
Chemical Properties ◽  
Perennial Herb ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Physical Strength ◽  
Aerial Parts ◽  
Ethnomedicinal Uses

Maerua pseudopetalosa (Gilg & Gilg-Ben.) DeWolf  is  a perennial herb or subshrub collected from the wild as a food plant or traditional medicine. Maerua pseudopetalosa occurs naturally from Senegal, east to Eritrea and Ethiopia, through South Sudan, Sudan, East Africa, south to the Democratic Republic of Congo (DRC). This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of M. pseudopetalosa. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the fruit, leaf and root infusion and/or decoction of M. pseudopetalosa are mainly used as a stimulant and to restore physical strength and vitality, and traditional medicine for chest pains, breast cancer and cough. Phytochemical compounds identified from aerial parts, fruits, roots, seeds and tubers of M. pseudopetalosa  include quaternary ammonium compounds, alkaloids, amino acids, betaines, cardiac glycosides, fatty acids, essential oils, flavonoids, phenolics, sterols and tannins. Preliminary ethnopharmacological research revealed that aerial parts, roots and tubers of M. pseudopetalosa have antibacterial, antifungal, antihyperglycemic, antioxidant, α-glucosidase inhibitory, pancreatic lipase inhibitory and cytotoxicity activities. Maerua pseudopetalosa should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.

scholarly journals A synthesis and review of medicinal uses, phytochemistry and biological activities of Markhamia zanzibarica

2020 ◽  
Vol 11 (4) ◽  
pp. 5985-5993
Author(s):  
Alfred Maroyi
Keyword(s):  
Respiratory Infections ◽  
Biological Activities ◽  
Clinical Effectiveness ◽  
Pharmaceutical Products ◽  
Future Research ◽  
Extensive Literature ◽  
Medicinal Uses ◽  
In Vivo Experiments

Markhamia zanzibarica (Bojer ex DC.) K. Schum.has been used in herbal medicine in tropical Africa since ancient times. Markhamia zanzibarica is indigenous to central, eastern and southern Africa. This extensive literature review synthesizes the information currently available on the medicinal uses, phytochemistry and biological activities of M. zanzibarica. The University library and electronic search engines Google Scholar, Scopus, Web of Science, ScienceDirect and PubMed were searched for pertinent information on the medicinal uses, phytochemistry and biological activities of M. zanzibarica. Traditionally, the species has been used as anthelmintic, and traditional medicine for backache, female reproductive problems, sexually transmitted infections, respiratory infections and gastro-intestinal problems. In vitro studies have confirmed the biological activities of M. zanzibarica which include antibacterial, antimycobacterial, antioxidant and cytotoxicity. Various phytochemicals such as alkaloids, anthraquinones, fatty acids, flavonoids, glycosides, phenolics, saponins, sterols, tannins and triterpenes have been isolated from M. zanzibarica. Documentation of the medicinal uses, phytochemistry and pharmacological properties of M. zanzibarica is essential as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. However, further pharmacological studies including phytochemical, toxicological, in vitro and in vivo experiments are needed to provide evidence for the clinical effectiveness of remedies prepared from the species.

scholarly journals MEDICINAL USES, BIOLOGICAL AND CHEMICAL PROPERTIES OF WILD GRAPE (LANNEA EDULIS): AN INDIGENOUS FRUIT PLANT OF TROPICAL AFRICA

2019 ◽  
pp. 16-20 ◽  
Author(s):  
ALFRED MAROYI
Keyword(s):  
Herbal Medicine ◽  
Biological Activities ◽  
Chemical Properties ◽  
Tropical Africa ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Birth Canal ◽  
Additional Information ◽  
Gastrointestinal Problems ◽  
Cytotoxicity Activities

Lannea edulis is a fruit plant widely used as herbal medicine throughout its distributional range in tropical Africa. This study was aimed at providing a critical review of the biological activities, phytochemistry, and medicinal uses of L. edulis. Documented information on the botany, biological activities, medicinal uses, and phytochemistry of L. edulis was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the botany, biological activities, phytochemistry, and medicinal uses of L. edulis was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the University library. This study showed that the bark, leaves, rootbark, and roots of L. edulis are used as antiabortifacient and herbal medicine to dilate birth canal, dizziness, sore eyes, sexually transmitted diseases, amenorrhea and dysmenorrhea, malaria, bilharzia, and gastrointestinal problems. Ethnopharmacological research revealed that L. edulis extracts and compounds have anthelmintic, anti-human immunodeficiency virus, antihyperglycemic, antihyperlipidemic, antimalarial, antimicrobial, antioxidant, and cytotoxicity activities. Future studies should focus on conducting detailed phytochemical, pharmacological, and toxicological evaluations of L. edulis crude extracts as well as compounds isolated from the species.

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