scholarly journals HELICHRYSUM CYMOSUM (L.) D.DON (ASTERACEAE): MEDICINAL USES, CHEMISTRY, AND BIOLOGICAL ACTIVITIES

Author(s):  
ALFRED MAROYI

Helichrysum cymosum is a valuable and well-known medicinal plant in tropical Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. cymosum. Information on medicinal uses, phytochemistry and biological activities of H. cymosum, was collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that H. cymosum is traditionally used as a purgative, ritual incense, and magical purposes and as herbal medicine for colds, cough, fever, headache, and wounds. Ethnopharmacological research revealed that H. cymosum extracts and compounds isolated from the species have antibacterial, antioxidant, antifungal, antiviral, anti-HIV, anti-inflammatory, antimalarial, and cytotoxicity activities. This research showed that H. cymosum is an integral part of indigenous pharmacopeia in tropical Africa, but there is lack of correlation between medicinal uses and existing pharmacological properties of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. cymosum extracts and compounds isolated from the species.

Author(s):  
ALFRED MAROYI

Helichrysum petiolare is a valuable and well-known medicinal herb in South Africa. A comprehensive review of phytochemical, medicinal uses, and biological activities of H. petiolare is presented in this study. Information on biological activities, medicinal uses, and phytochemistry of H. petiolare was gathered from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information on these aspects was sourced from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. The current study revealed that H. petiolare is mainly used as herbal medicine for respiratory infections, diabetes, fever, headache, heart problem, high blood pressure, pain, reproductive problems, and wounds. Phytochemical studies showed that H. petiolare extracts and compounds isolated from the species have antifungal, anti-inflammatory, antibacterial, antioxidant, antityrosinase, antigenotoxicity, and cytotoxicity activities. This research showed that H. petiolare is an integral part of indigenous pharmacopeia in South Africa, but there is the lack of alignment between the known medicinal applications, phytochemistry, and biological activities of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. petiolare extracts and compounds associated with the species.


Author(s):  
ALFRED MAROYI

Helichrysum odoratissimum is an important medicinal plant species in tropical Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. odoratissimum. Information on medicinal uses, phytochemistry and biological activities of H. odoratissimum were collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the university library. This study showed that H. odoratissimum is mainly used as an herbal medicine for insomnia, menstrual pain and sterility, and wounds and respiratory problems. Pharmacological research revealed that H. odoratissimum extracts and compounds isolated from the species have antibacterial, antimycobacterial, antifungal, anti-inflammatory, antioxidant, hepatoprotection, and hypoglycemic and cytotoxicity activities. There is a need to validate the documented ethnomedicinal uses of H. odoratissimum through phytochemical and pharmacological studies. Therefore, future studies should address these knowledge gaps through experimental animal studies, randomized clinical trials, and target-organ toxicity studies involving H. odoratissimum crude extracts and compounds isolated from the species.


Author(s):  
ALFRED MAROYI

Zantedeschia aethiopica is an evergreen monocotyledonous herb widely used as herbal medicine and ornamental plant. The current study is aimed at reviewing the medicinal uses, phytochemistry, and biological activities of Z. aethiopica. Information on biological activities, medicinal uses, and phytochemistry of Z. aethiopica was gathered from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information on these aspects was sourced from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University Library. The current study revealed that Z. aethiopica is mainly used as herbal medicine for boils, burns, gout, inflammation, insect bites, rheumatism, sores, and wounds. Phytochemical and pharmacological studies showed that Z. aethiopica extracts and compounds isolated from the species have antibacterial, antifungal, antioxidant, antihistaminic, antialgal, antithrombotic, and anticoagulant activities. This research showed that Z. aethiopica is an integral part of the traditional pharmacopeia in several countries where the species is indigenous or naturalized, but there is the lack of alignment between the known medicinal applications, phytochemistry, and biological activities of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of Z. aethiopica extracts and compounds associated with the species.


Author(s):  
ALFRED MAROYI

Helichrysum longifolium and Helichrysum pedunculatum have a long history of medicinal use, particularly managing wounds acquired during male circumcision rites in South Africa. There is a need to evaluate the existence of any correlation between the ethnomedicinal applications, the phytochemistry and pharmacological properties of the species. Therefore, in this review, analyses of the botanical, medicinal, and chemical and biological activities of H. longifolium and H. pedunculatum are presented as well as exploring the potential of the two species as important sources of health and pharmaceutical products. Information on the botany, medicinal uses, and phytochemistry and biological activities of H. longifolium and H. pedunculatum was assembled from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was sourced from journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that alkaloids, flavonoids, linoleic acid, oleic acid, phenol, proanthocyanidin, saponins, and tannins have been identified from the leaves of H. longifolium and H. pedunculatum. The pharmacological research showed that H. longifolium and H. pedunculatum extracts and compounds isolated from the species have antibacterial, antifungal, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, and cytotoxicity activities. For local communities to use H. longifolium and H. pedunculatum extracts with confidence as herbal medicines, there is a need for extensive phytochemical and pharmacological studies. Further research is required to establish the safety profiles of different H. longifolium and H. pedunculatum preparations.


Author(s):  
ALFRED MAROYI

Drimia elata is an important and well-known medicinal plant in tropical Africa. This study critically reviewed the medicinal applications, phytochemistry, and pharmacological activities of D. elata. Literature on medicinal applications, phytochemical, and pharmacological activities of D. elata was collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, PubMed, BMC, ScienceDirect, and Scopus. Complementary information was gathered from pre-electronic sources such as books, book chapters, theses, scientific reports, and journal articles obtained from the university library. This study showed that D. elata is used for treating several medical conditions, particularly general ailments, blood and cardiovascular system, reproductive system and sexual health, urinary system, infections and infestations, digestive system, respiratory system, and muscular-skeletal system disorders. Phytochemical compounds identified from the species include bufadienolides, alkaloids, aromatic acids, flavonoids, phlobatannins, saponins, steroids, tannins, and terpenoids. Ethnopharmacological research revealed that D. elata extracts have acetylcholinesterase enzyme inhibitory, antibacterial, antifungal, antimycobaceterial, anticancer, anti-inflammatory, antioxidant, hemagglutinating, and cytotoxicity activities. D. elata should be subjected to extensive in vivo experiments and also future studies should focus on how potential toxic components of the species can be managed when it is used as herbal medicine.


2020 ◽  
Vol 11 (4) ◽  
pp. 5876-5885
Author(s):  
Alfred Maroyi

Gardenia ternifolia Schum. & Thonn. is a shrub or small tree widely used as a traditional medicine throughout its distributional range in tropical Africa. Gardenia ternifolia is widespread in tropical Africa, extending from Senegal eastwards to Ethiopia and Kenya, through the Democratic Republic of Congo (DRC) southwards to Namibia, South Africa and Mozambique. This study was aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of G. ternifolia. Documented information on the medicinal uses, phytochemistry and biological activities of G. ternifolia was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study showed that the species is widely used as an aphrodisiac and protective charm, and traditional medicine for headache, migraine, respiratory infections, sore eyes, hypertension, diabetes, gastro-intestinal problems, erectile dysfunction, malaria, convulsions and epilepsy. Phytochemical compounds identified from the species include alkaloids, anthocyanins, coumarins, flavonoids, phenols, quinones, saponins, steroids, stereoisomeric neolignans, tannins and terpenoids. Pharmacological research revealed that G. ternifolia extracts and compounds isolated from the species have antibacterial, antiviral, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antisickling, antitheilerial, hepatotoxicity, larvicidal and cytotoxicity activities. Future research on G. ternifolia should focus on detailed phytochemical evaluations, including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.


2020 ◽  
Vol 10 (2) ◽  
pp. 46-50
Author(s):  
Alfred Maroyi

Background: Aristea ecklonii is a perennial herb widely used as herbal medicine in southern Africa. Plants used as traditional medicines to treat various human diseases and illnesses play an important role in the primary healthcare of local communities in developing countries.Purpose: The current study critically reviewed the medicinal uses, phytochemistry and pharmacological properties of A. ecklonii.Methods: Literature on medicinal uses, phytochemical and pharmacological properties of A. ecklonii was collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, Pubmed, BMC, Science Direct, and Scopus. Additional information was also obtained from pre-electronic sources such as books, book chapters, theses, scientific reports and journal articles obtained from the university library.Results: This study revealed that A. ecklonii is used as an ornamental plant, protective charm, and herbal medicine for internal sores, cough, fever, syphilis, shingles, and venereal diseases. Ethnopharmacological research identified quinones and sterols from leaves and rhizomes of A. ecklonii. The crude extracts of A. ecklonii and the compound plumbagin isolated from the species exhibited antibacterial and antifungal activities.Conclusion: Aristea ecklonii should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 10 (5) ◽  
pp. 280-286
Author(s):  
Alfred Maroyi

Adenia gummifera (Harv.) Harms is a climber or liane widely used as traditional medicine throughout its distributional range in tropical Africa. Adenia gummifera occurs naturally in the Democratic Republic of Congo (DRC), Eswatini, Ethiopia, Kenya, Malawi, Mozambique, Seychelles, Somalia, South Africa, Tanzania, Uganda, Zambia and Zimbabwe. This study is aimed at providing a critical review of the medicinal uses, phytochemistry and biological activities of A. gummifera. Documented information on the medicinal uses, phytochemistry and biological activities of A. gummifera was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct. Additional information was gathered from pre-electronic sources such as book chapters, books, journal articles and scientific publications sourced from the university library. This study showed that the species is widely used as an emetic and a protective charm, and, as traditional medicine for infertility, sexually transmitted infections, gastro-intestinal infections, leprosy, respiratory infections, malaria and menstrual problems. Phytochemical compounds identified from the species include polyacetylenic diepoxide, alkaloids, flavonoids, flavonol, modeccin, proanthocyanidins, tetraphyllin, phenolics, polyphenol and tannins. Pharmacological research revealed that A. gummifera extracts and compounds isolated from the species have antibacterial, antifungal, acetylcholinesterase inhibitory (AChEI), anaesthetic, antioxidant, antiplasmodial and cytotoxicity activities. Future research on A. gummifera should focus on detailed phytochemical evaluations including toxicological, in vivo and clinical studies to corroborate the traditional medical applications of the species.


Author(s):  
ALFRED MAROYI

Helichrysum foetidum is a medicinal plant species with various medicinal applications among different ethnic groups in Africa, Asia, and Europe. This review was aimed at providing a critical appraisal of the existing medicinal uses, biological activities, and phytochemical components of H. foetidum. Literature search for information on medicinal uses, biological activities, and phytochemical components of H. foetidum was conducted using various online search engines such as Scopus, Google Scholar, Mendeley, and Web of Science. Additional information on these aspects was sourced from the university library. Literature studies revealed that H. foetidum is mainly used to induce trances and as herbal medicine against wounds, sores, dysmenorrhea, eye infections, influenza, and as a sedative. Phytochemical compounds identified from the species include chalcones, diterpenoids, flavanols, flavonoids, phenolics, phenols, and proanthocyanidins. Pharmacological studies revealed that H. foetidum extracts and compounds have antibacterial, antifungal, antiviral, antioxidant, protease-inhibiting, and cytotoxicity activities. There is a need for advanced phytochemical and pharmacological evaluations and clinical trials aimed at evaluating the therapeutic potential of H. foetidum in Africa, Asia, and Europe.


Author(s):  
ALFRED MAROYI

Lannea schimperi is a well-known fruit tree and medicinal plant in tropical Africa. The current study critically reviewed the botany, medicinal uses, phytochemistry, and pharmacological activities of L. schimperi. Literature on botany, medicinal uses, phytochemical and biological activities of L. schimperi were collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, PubMed, BMC, ScienceDirect, and Scopus. Complementary information was gathered from pre-electronic sources such as books, book chapters, theses, scientific reports, and journal articles obtained from the University Library. This study revealed that the species is used as a source of fiber, edible fruits, and herbal medicine. Phytochemical compounds identified from the species include cyclohexenones, cardanols, alkaloids, anthocyanins, anthracene glycosides, carbohydrates, cardiac glycosides, carotenoids, condensed tannins, coumarins, flavonoids, phenolic glycosides, phenols, polyoses, polyuronoids, reducing sugars, saponins, steroids, tannins, triterpenoids, and volatile compounds. Pharmacological research revealed that extracts and phytochemical constituents isolated from L. schimperi have anesthetic, antibacterial, antifungal, anticoccidial, anti-inflammatory, antinociceptive, antioxidant, anti-trypanosoma, antiulcerogenic, cytotoxicity, and toxicity activities. L. schimperi should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities of the species.


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