A study of histopathological correlation of abnormal uterine bleeding with clinical symptoms

2020 ◽  
Vol 16 (2) ◽  
pp. 17-22
Author(s):  
Neha G Jagdale ◽  
Keyword(s):  
Clinical Symptoms ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Histopathological Correlation

scholarly journals Clinico-histopathological and ultrasonographic correlation of abnormal uterine bleeding in perimenopausal and postmenopausal women

2021 ◽  
Vol 10 (6) ◽  
pp. 2408
Author(s):  
Sharanya . ◽  
Julie Thomas
Keyword(s):  
Data Entry ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Common Finding ◽  
Ethical Review ◽  
Histopathological Correlation ◽  
Endometrial Pattern ◽  
Endometrial Hyperplasia With Atypia ◽  
Observational Group ◽  
A Prospective Study

Background: Abnormal uterine bleeding (AUB) accounts for one of the most common gynaecological problem, almost one third of total cases. The study was a prospective study done from December 2017 to November 2019. The histopathological reports of endometrial pattern as well as that of hysterectomy specimens were correlated with clinical diagnosis and ultrasonographic findings. The main objective was to study the correlation between clinical, ultrasonographic and histopathological correlation of AUB in perimenopausal, menopausal and postmenopausal women.Methods: Formal Permission was obtained from the administrator of St. Philomena’s hospital. Ethical clearance was obtained from institutional ethical review board of St. Philomena’s hospital. Informed consent was obtained from observational group and confidentiality was assured.  Data entry and analyses was done using the Statistical Package for Social Sciences (SPSS) for Windows software (version 20.0; SPSS Inc, Chicago).Results: A total number of 165 cases were studied. Maximum women were in the age group of 40-55 years 87.27%. Most common presentation of abnormal uterine bleeding is menorrhagia which accounts for 72.7% of women (120 women). The most common finding noted in USG was fibroid uterus which accounts for 44.2% of women (73 women). Most commonly observed histological pattern noted were proliferative (62.4%) followed by secretory endometrium (8.5%) and simple endometrial hyperplasia with atypia (8.5%).Conclusions: In conclusion, AUB is one of the most common condition for which patients seek advice in the gynaecological outpatient department. Analysis of histopathology of endometrium in abnormal uterine bleeding helps in management of patients and to know the pathological incidence of structural causes in AUB prior to surgery.

scholarly journals Chronic endometritis and endometriosis: is there an interrelationship?

2021 ◽  
Vol 10 (3) ◽  
pp. 83-91
Author(s):  
N.Y. Pedachenko ◽  
R.A. Tukhtarian ◽  
I.L. Avetis'yan ◽  
T.L. Shemelko
Keyword(s):  
Pelvic Pain ◽  
Medical Information ◽  
Clinical Symptoms ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Cochrane Library ◽  
Control Group ◽  
Chronic Endometritis ◽  
Timely Diagnosis ◽  
Inflammatory Processes

Background. Chronic endometritis and endometriosis have a lot in common. Both diseases are long-term inflammatory processes, with definitively unspecified etiological factors and pathogenetic mechanisms that negatively affect fertility and may cause pelvic pain or abnormal uterine bleeding. The issue of effective and timely diagnosis of chronic endometritis remains open due to the lack of specific clinical symptoms and clinical examination data. Assessment of current scientific evidence of the interrelationship between endometriosis and chronic endometritis. Materials and methods. A systematic search of scientific medical information has been conducted in English-language databases: MEDLINE, Scopus, Web of Science, Medline, The Cochrane Library, PubMed. Results. According to the review of various scientific studies that have recently been conducted, it has been found that patients with endometriosis statistically have a significantly higher risk of developing chronic endometritis by 1.3-2.5 times than women without endometriosis. Using a histological endometrial study and detection of CD138, chronic endometritis was found in 52.94 % of women in the endometriosis group and in 27.02 % of patients in the endometriosis-free group; the rate was significantly higher in the endometriosis group than in the control group (p = 0.0311). Moreover, 76% of women with endometriosis showed inflammatory processes of pelvic organs (compared to the control group, where inflammation was found in 38.4 % of women, p < 0.0001). Conclusions. Patients with endometritis demonstrate a positive correlation with development of endometriosis. Given the inability to establish a causal relationship between endometriosis and chronic endometritis, extended diagnosis is necessary to eliminate chronic endometritis, especially if women have abnormal uterine bleeding or chronic pelvic pain. The combination of histological and immunohistochemical endometrial examination methods has shown its effectiveness in timely diagnosis of chronic endometritis. Identifying and adequately treating this condition will help avoid unnecessary surgery.

scholarly journals A clinical study of diagnostic hysteroscopy in abnormal uterine bleeding and its histopathological correlation

2018 ◽  
Vol 7 (2) ◽  
pp. 396
Author(s):  
Shanmugapriya Kumaresan ◽  
Devika Perumal
Keyword(s):  
Tamil Nadu ◽  
Abnormal Uterine Bleeding ◽  
High Sensitivity ◽  
Clinical Problem ◽  
Uterine Bleeding ◽  
College Hospital ◽  
Histopathological Correlation ◽  
Diagnostic Hysteroscopy ◽  
Sensitivity Specificity ◽  
A Prospective Study

Background: Abnormal uterine bleeding is a common clinical problem with myriad of causes. The diagnosis and management of abnormal menstrual function must be based on an understanding of the physiologic mechanisms involved in the regulation of the normal cycles. Diagnostic hysteroscopy is a valuable tool in diagnosing structural intra-cavital pathology, very suitable for out-patient clinic.Methods: This is a prospective study which has been carried out in the Department of Obstetrics and Gynecology, Tirunelveli medical college hospital, Tirunelveli, Tamil Nadu from January 2011 to October 2011.Results: A total of 50 cases were analysed among the 50 patients tested. 26 patients had some pathology of which 24were accurately detected by hysteroscopy, missed 2 cases of irregular shedding endometrium which was reported by histopathology.Conclusions: Hysteroscopy is a safe, reliable and quick procedure in the diagnosis of cases with abnormal uterine bleeding with high sensitivity, specificity and negative predictive value.

scholarly journals Role of sonohysterography in evaluation of abnormally thickened endometrium causing abnormal uterine bleeding with histopathological correlation

2014 ◽  
Vol 40 (1) ◽  
pp. 10-14 ◽  
Author(s):  
S Parveen ◽  
SA Azad ◽  
J Mohammad ◽  
S Haque ◽  
RS Shanta ◽  
...  
Keyword(s):  
Predictive Value ◽  
Randomized Study ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Transvaginal Sonography ◽  
Histopathological Diagnosis ◽  
Initial Examination ◽  
College Hospital ◽  
Histopathological Correlation ◽  
Endometrial Pathology

This prospective randomized study was carried out in the department of Radiology and Imaging in collaboration with the department of Obstetrics and Gynecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag and Dhaka Medical College Hospital (DMCH) during the period of January 2003 to December 2004. The aim of this study was to establish sonohyterography as a sensitive tool and superior to Transvaginal Sonography (TVS) for detection of endometrial pathology in women with abnormal uterine bleeding (AUB) and its validity by determining sensitivity, specificity, accuracy, positive predictive value and negative predictive value. For this purpose, a total number of 40 patients who had thickened endometrium (cut off level <15 mm for pre menopausal and <5 mm for post menopausal patients) detected on transabdominal or transvaginal sonography were selected. TVS and TV-SH were done in all these patients and findings were then compared with the final histopathological diagnosis. In our study, we found TV-SH has sensitivity of 100%, specificity of 80% and accuracy of 97.5 % compared to TVS (94 %, 66.66 % and 90 % respectively) in detection of endometrial pathology in women with AUB. TV-SH can thus be regarded as one of the most sensitive, specific and accurate modality in detecting and excluding endoluminal masses as the cause of AUB. It can be considered as the initial examination in the evaluation of all women with AUB. DOI: http://dx.doi.org/10.3329/bmrcb.v40i1.20322 Bangladesh Med Res Counc Bull 2014; 40: 10-14

Sign in / Sign up

Export Citation Format

Share Document