SUPERCRITICAL CARBON DIOXIDE BRAYTON CYCLES ANALYSIS FOR HIGH CONCENTRATION LINEAR FRESNEL COLLECTOR APPLICATIONS

The studies of solubility of the paprika extract with a high concentration of carotenoids in carbon dioxide under the pressure of 20–50 MPa and at temperatures of 313.15–333.15 K were carried out using the static method. The highest solubility of paprika extract was achieved at the temperature of 333.15 K and under the pressure of 50 MPa. The obtained experimental data were correlated with five density-based models, applied for prediction of solubility in the supercritical carbon dioxide (the Chrastil, del Valle and Aguilera, Adachi and Lu, Sparks et al. and Bian et al. models). The accuracy of particular models with reference to measurement results was specified with the average absolute relative deviation (AARD) and coefficient of determination (R2). Results showed that solubility calculated based on the selected models was compliant with experimental data.

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Supercritical carbon dioxide Cannabis sativa L. and Humulus lupulus extracts and their influence on human macrophages inflammatory state*

Postępy Higieny i Medycyny Doświadczalnej ◽

10.5604/01.3001.0013.6827 ◽

2019 ◽

Vol 73 ◽

pp. 782-790

Author(s):

Aleksandra Gregorius ◽

Wojciech Krzyczkowski ◽

Marta Wierucka ◽

Julia Kupińska ◽

Agnieszka Dębczak ◽

...

Keyword(s):

Carbon Dioxide ◽

Supercritical Carbon Dioxide ◽

Inflammatory Cytokines ◽

Cannabis Sativa ◽

Humulus Lupulus ◽

High Concentration ◽

Inflammatory State ◽

Pro Inflammatory Cytokines ◽

Supercritical Carbon

Herbal extracts are promising immunomodulating compounds. Their standardization may improve clinical outcome in various conditions related to inflammatory state. The aim of this study was to assess the utility of Cannabis sativa L. and Humulus lupulus extracts obtained by supercritical carbon dioxide (scCO2) in the reduction of pro-inflammatory cytokines release after LPS stimulation in the in vitro model. After scCO2 extraction, the cytotoxic potential of the obtained compounds was determined. The highest non-cytotoxic concentrations were selected for further inflammatory testing. PMA-differentiated U937 cells were used as an LPS induced model of the inflammation to assess the extracts potential to decrease the level of the pro-inflammatory cytokines IL-1β, IL-6 and TNF-α. Either individually tested or in combination scCO2 extracts markedly reduced the level of released pro-inflammatory cytokines in comparison to LPS stimulated positive control. Our results show that the usage of standardized Cannabis sativa L. and Humulus lupulus extracts might be beneficial in reducing the inflammatory state. Application of the mixed extracts not only reduces the need for a high concentration of pure compounds, but also broadens the possible therapeutic effect. Moreover, scCO2 extraction may serve as the efficient method of obtaining functional anti-inflammatory extracts from either hop cones or cannabis.

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Extraction of β-sitosterol from Swietenia mahagoni seeds by using supercritical carbon dioxide (SC-CO2) extraction

Malaysian Journal of Fundamental and Applied Sciences ◽

10.11113/mjfas.v14n3.1082 ◽

2018 ◽

Vol 14 (3) ◽

pp. 411-417

Author(s):

Nur Salsabila Md Norodin ◽

Liza Md Salleh ◽

Siti Machmudah ◽

Nik Musaadah Mustafa ◽

Hartati Hartati ◽

...

Keyword(s):

Experimental Data ◽

Carbon Dioxide ◽

Response Surface Methodology ◽

Supercritical Carbon Dioxide ◽

Response Surface ◽

Oil Yield ◽

High Concentration ◽

Order Polynomial ◽

Swietenia Mahagoni ◽

Supercritical Carbon

This work investigates the effect of supercritical carbon dioxide (SC-CO2) extraction conditions (pressure and temperature) on the oil yield and β-sitosterol content extracted from Swietenia mahagoni seeds by using response surface methodology (RSM). The experimental data obtained were fitted to a second-order polynomial model and the obtained oil yields were 1.49-14.45%, while β-sitosterol content obtained were 3.12-9.20 mg/g. The best conditions within the ranges studied were 30 MPa and 40°C to extract β-sitosterol in the highest amount. The present findings show that S. mahagoni seeds extract has a high concentration of β-sitosterol.

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