scholarly journals Respiratory syncytial virus infection among young children with acute respiratory tract infection in Iraq

1999 ◽  
Vol 5 (5) ◽  
pp. 941-948
Author(s):  
K. A. Albargish ◽  
H. J. Hasony
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Respiratory Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Acute Respiratory Infection ◽  
Acute Respiratory Tract Infection ◽  
Control Group ◽  
Severe Acute Respiratory Infection ◽  
Syncytial Virus ◽  
Children Under 5

The incidence of respiratory syncytial virus infection was assessed among 516 children under 5 years with acute respiratory infection and 57 control children free of respiratory infection to determine its relation to epidemiological variables. Respiratory syncytial virus was detected in 188 [37.6%]children with acute respiratory infection and in none of the control group. The infection was highest in those with severe acute respiratory infection, particularly severe bronchiolitis and pneumonia and it precipitated acute bronchial asthma in children over 2 years. The infection was most common in the first 6 months and both sexes were equally affected. Socioeconomic factors and crowding played no significant role in the incidence and spread of the infection. Breastfeeding had no clear protective effect against the infection

scholarly journals Severe respiratory disease caused by human respiratory syncytial virus impairs language learning during early infancy

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Marcela Peña ◽  
Cristina Jara ◽  
Juan C. Flores ◽  
Rodrigo Hoyos-Bachiloglu ◽  
Carolina Iturriaga ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Language Learning ◽  
Respiratory Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Learning Difficulties ◽  
Human Respiratory Syncytial Virus ◽  
Severe Respiratory Infection ◽  
Syncytial Virus

AbstractHuman respiratory syncytial virus infection is a leading cause of pediatric morbidity and mortality. A previous murine study showed that during severe acute respiratory infections the virus invades the central nervous system, and that infected animals evolve with long-lasting learning difficulties associated with long-term potentiation impairment in their hippocampus. We hypothesized here that human infants who presented a severe episode of respiratory syncytial virus infection before 6 months of age would develop long-term learning difficulties. We measured the acquisition of the native phoneme repertoire during the first year, a milestone in early human development, comprising a reduction in the sensitivity to the irrelevant nonnative phonetic information and an increase in the sensitivity to the information relevant for the native one. We found that infants with a history of severe respiratory infection by the human respiratory syncytial virus presented poor distinction of native and nonnative phonetic contrasts at 6 months of age, and remained atypically sensitive to nonnative contrasts at 12 months, which associated with weak communicative abilities. Our results uncover previously unknown long-term language learning difficulties associated with a single episode of severe respiratory infection by the human respiratory syncytial virus, which could relate to memory impairments.

scholarly journals WHEEZE ASSOCIATED RESPIRATORY SYNCYTIAL VIRUS INFECTION AND ITS PREVENTION

2003 ◽  
Vol 40 (139) ◽  
pp. 156-161
Author(s):  
A Thaplial ◽  
U Ramachandran
Keyword(s):  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Respiratory Infection ◽  
Respiratory Syncytial Virus Infection ◽  
Lower Respiratory Infection ◽  
Syncytial Virus

Wheeze associated respiratory infection is an important cause of morbidity andmortality in both the developed and the developing worlds. The commonest causativeagent is the Respiratory Syncytial Virus (RSV). Lower respiratory infection with thisvirus is assuming great proportions and hence much work is being done to find a cureor at least a suitable vaccine that will be available to everyone even in the poorercountries. This article reviews the latest literature and attempts to set out someguidelines to help inreduction of the problems associated with lower respiratoryinfection caused by RSV in developing countries.Key Words : Lower respiratory infection, Respiratory Syncytial Virus.

scholarly journals Recommendations for respiratory syncytial virus surveillance at national level

2021 ◽  
pp. 2003766
Author(s):  
Anne C. Teirlinck ◽  
Eeva K. Broberg ◽  
Are Stuwitz Berg ◽  
Harry Campbell ◽  
Rachel M. Reeves ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Young Children ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Global Analysis ◽  
National Level ◽  
Common Cause ◽  
Severe Acute Respiratory Infection ◽  
Syncytial Virus ◽  
Tract Infections

Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infections (ALRI) and hospitalisations among young children and is globally responsible for many deaths in young children, especially in infants below 6 months of age. Furthermore, RSV is a common cause of severe respiratory disease and hospitalisation among the elderly. The development of new candidate vaccines and monoclonal antibodies highlights the need for reliable surveillance of RSV. In the European Union (EU), no up-to-date general recommendations on RSV surveillance are currently available. Based on outcomes of a workshop with 29 European experts in the field of RSV virology, epidemiology and public health, we provide recommendations to develop a feasible and sustainable national surveillance strategy for RSV that will enable harmonisation and data comparison at the European level. We discuss three surveillance components: active sentinel community surveillance, active sentinel hospital surveillance, and passive laboratory surveillance, using the EU acute respiratory infection (ARI) and WHO extended severe acute respiratory infection (SARI) case definitions. Furthermore, we recommend the use of quantitative reverse transcription polymerase chain reaction (qRT-PCR) based assays as the standard detection method for RSV and virus genetic characterisation, if possible, to monitor genetic evolution. These guidelines provide a basis for a good quality, feasible and affordable surveillance of RSV. Harmonisation of surveillance standards at European and global level will contribute to the wider availability of national level RSV surveillance data for regional and global analysis, and estimation of the RSV burden and impact of the future immunisation programmes.

scholarly journals Capturing respiratory syncytial virus season in Belgium using the influenza severe acute respiratory infection surveillance network, season 2018/19

2020 ◽  
Vol 25 (39) ◽  
Author(s):  
Lorenzo Subissi ◽  
Nathalie Bossuyt ◽  
Marijke Reynders ◽  
Michèle Gérard ◽  
Nicolas Dauby ◽  
...  
Keyword(s):  
Older Adults ◽  
Respiratory Syncytial Virus ◽  
Respiratory Infection ◽  
Acute Respiratory Infection ◽  
Case Definition ◽  
World Health ◽  
Surveillance Network ◽  
Severe Acute Respiratory Infection ◽  
Respiratory Syncytial Virus Season ◽  
Syncytial Virus

Background Respiratory syncytial virus (RSV) is a common cause of severe respiratory illness in young children (< 5 years old) and older adults (≥ 65 years old) leading the World Health Organization (WHO) to recommend the implementation of a dedicated surveillance in countries. Aim We tested the capacity of the severe acute respiratory infection (SARI) hospital network to contribute to RSV surveillance in Belgium. Methods During the 2018/19 influenza season, we started the SARI surveillance for influenza in Belgium in week 40, earlier than in the past, to follow RSV activity, which usually precedes influenza virus circulation. While the WHO SARI case definition for influenza normally used by the SARI hospital network was employed, flexibility over the fever criterion was allowed, so patients without fever but meeting the other case definition criteria could be included in the surveillance. Results Between weeks 40 2018 and 2 2019, we received 508 samples from SARI patients. We found an overall RSV detection rate of 62.4% (317/508), with rates varying depending on the age group: 77.6% in children aged < 5 years (253/326) and 34.4% in adults aged ≥ 65 years (44/128). Over 90% of the RSV-positive samples also positive for another tested respiratory virus (80/85) were from children aged < 5 years. Differences were also noted between age groups for symptoms, comorbidities and complications. Conclusion With only marginal modifications in the case definition and the period of surveillance, the Belgian SARI network would be able to substantially contribute to RSV surveillance and burden evaluation in children and older adults, the two groups of particular interest for WHO.

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